Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie最新文献

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Transduction of Amikacin, Gentamicin and Tobramycin Resistance in Pseudomonas aeruginosa 铜绿假单胞菌对阿米卡星、庆大霉素和妥布霉素耐药的转导
H. Knothe , V. Krčméry , S. Mitsuhashi
{"title":"Transduction of Amikacin, Gentamicin and Tobramycin Resistance in Pseudomonas aeruginosa","authors":"H. Knothe ,&nbsp;V. Krčméry ,&nbsp;S. Mitsuhashi","doi":"10.1016/S0172-5599(80)80075-7","DOIUrl":"https://doi.org/10.1016/S0172-5599(80)80075-7","url":null,"abstract":"<div><p>In a series of <em>Pseudomonas aeruginosa</em> strains resistant to gentamicin, tobramycin, amikacin and/or netilmicin (<em>Knothe</em> and <em>Krčméry</em>, 1979), wild-type phage lysates could be prepared and two of them were studied more in detail. Both lysates were shown to mediate transfer of gentamicin, amikacin and carbenicillin resistance by direct selection. In some instances also fertility function <em>(tra)</em> could be demonstrated in transductants by further cycles of transfer. It could be speculated that, once such wild-type phages from resistant or toxinogenic strains are liberated into the hospital environment, they could mediate these and other properties to <em>P. aeruginosa</em> strains in that environment.</p></div>","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"246 3","pages":"Pages 373-378"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80075-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91739752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Lipase- und Antilipasestudien mit Vertretern der Genera Serratia, Aeromonas und Vibrio 这是为聚会准备的研究报告
F. Caselitz, V. Freitag, H. Meyer
{"title":"Lipase- und Antilipasestudien mit Vertretern der Genera Serratia, Aeromonas und Vibrio","authors":"F. Caselitz, V. Freitag, H. Meyer","doi":"10.1016/S0172-5599(80)80071-X","DOIUrl":"https://doi.org/10.1016/S0172-5599(80)80071-X","url":null,"abstract":"","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"50 1","pages":"336-343"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90676260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Antioncogenic Activity of Influenza Virus on Polyoma Virus Induced Renal and Brain Tumors in Newborn Wistar Rats 流感病毒对新生Wistar大鼠多瘤病毒诱导的肾和脑肿瘤的抗逆性活性
G. Noss , G. Stauch
{"title":"Antioncogenic Activity of Influenza Virus on Polyoma Virus Induced Renal and Brain Tumors in Newborn Wistar Rats","authors":"G. Noss ,&nbsp;G. Stauch","doi":"10.1016/S0172-5599(80)80065-4","DOIUrl":"10.1016/S0172-5599(80)80065-4","url":null,"abstract":"<div><p>Simultaneous inoculation of newborn Wistar rats with intact A/PR 8/34 (HON1) influenza virus and the S.E. strain of polyoma virus resulted in significant reduction of the rates of both kidney sarcomas and brain tumors in comparison to controls given polyoma virus, only. This antioncogenic activity (AOA) of influenza virus was observed independently whether or not influenza and polyoma virus were injected on different sites or were inoculated as a combined vaccine. Ether-treated A/PR 8/34 influenza virus was found to have also AOA. However, in one experiment a significant AOA was demonstrated with respect to brain tumors, only, and not for the rate of renal sarcomas. In addition, the influenza strain A/Hong Kong/1/68 (H3N2) was found to have AOA.</p></div>","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"246 3","pages":"Pages 285-293"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80065-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75042459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Mechanized Technique for Phage Typing and Determination of Antibiograms 噬菌体分型及抗生素谱测定的机械化技术
P.A.M. GuinÉe , W.H. Jansen, A. van Schuylenburg, W.J. van Leeuwen
{"title":"Mechanized Technique for Phage Typing and Determination of Antibiograms","authors":"P.A.M. GuinÉe ,&nbsp;W.H. Jansen,&nbsp;A. van Schuylenburg,&nbsp;W.J. van Leeuwen","doi":"10.1016/S0172-5599(80)80118-0","DOIUrl":"10.1016/S0172-5599(80)80118-0","url":null,"abstract":"<div><p>A device for mechanical application of either drops of phage suspensions or antibiotic-containing tablets was developed. The device consists of a Transport Apparatus which transports petri dishes from one side of the apparatus to the other in such a way that the plate and the lid of a petri dish become entirely separated at a particular stage. Either a Phage Applicating System or an Antibiotic Tablet Dispenser can be connected to the apparatus. In this way a maximum of 27 phages or 7 antibiotic tablets per plate can be applied pneumatically.</p><p>Zusammenfassung</p><p>Ein Gerät für die mechanisierte Applikation von Bakteriophagentropfen oder Antibiotika enthaltende Tabletten ist entwickelt worden. Das Gerät umfaßt einen Transportapparat, der Petrischalen von einer Scite des Apparates nach der anderen Scite transportiert, wobei die Platte und der Deckel der Schalen in einer bestimmten Phase völlig voneinander getrennt sind. Das Phagen-Applikations-System oder der Antibiotika-Tabletten-Dispenser kann mit dem Transportapparat verbunden werden. Maximal 27 Phagen oder 7 Antibiotika- tabletten können gleichzeitig auf die Platten appliziert werden.</p></div>","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"246 2","pages":"Pages 276-284"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80118-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82740978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
O-Antigenbestimmung und Identifizierung von Pseudomonas aeruginosa 检测并识别伪龙葵素
R. Ansorg
{"title":"O-Antigenbestimmung und Identifizierung von Pseudomonas aeruginosa","authors":"R. Ansorg","doi":"10.1016/S0172-5599(80)80113-1","DOIUrl":"10.1016/S0172-5599(80)80113-1","url":null,"abstract":"<div><p>The quality of the morphological-biochemical identification of <em>P. aeruginosa</em> affects the results of group determination with anti-O-sera (Institute Pasteur Production) to a great extent. Out of 563 isolates classified as <em>P. aeruginosa</em> on the basis of colony morphology, haemolysis, pigment formation, odor, gramstaining and oxidase test, 84,2% react with one monovalent antiserum. Out of 498 strains which are more exactly identified by additional use of the Oxi/Ferm tube-system (Hoffmann-La Roche), 94,0% are clearly to be grouped. The O-antigen determination is not appropriate for inter-species differentiation of <em>P. aeruginosa</em>, due to common antigens with <em>P. aeruginosa</em> related species.</p><p>Zusammenfassung</p><p>Die Qualität der morphologisch-biochemischen Identifizierung von <em>P. aeruginosa</em> bestimmt in starkem Maße die Ergebnisse der Gruppenbestimmung mit Anti-O-Seren (Institut Pasteur Production). Von 563 auf Grund von Koloniemorphologie, Hämolyse, Pigmentbildung, Geruch, Gramverhalten und Oxidasereaktion als <em>P. aeruginosa</em> klassifizierten Isolaten reagieren 84,2% mit einem monovalenten Antiserum. Von 498 durch zusätzliche Verwendung des Oxi/Ferm Tube-Systems (Hoffmann-La Roche) präziser identifizierten Stämmen sind 94,0% eindeutig gruppierbar. Die O-Antigenbestimmung ist zur Inter-Species-Differenzierung von <em>P. aeruginosa</em> ungeeignet, da Antigengemeinschaften mit <em>P. aeruginosa</em>-ähnlichen Species bestehen.</p></div>","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"246 2","pages":"Pages 197-203"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80113-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82796473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Passiver Haemagglutinationstest für Semliki-Forest-Virus 检测赛姆利克灾难病毒
O.J.B. Hübschle , F. Weiland
{"title":"Passiver Haemagglutinationstest für Semliki-Forest-Virus","authors":"O.J.B. Hübschle ,&nbsp;F. Weiland","doi":"10.1016/S0172-5599(80)80107-6","DOIUrl":"10.1016/S0172-5599(80)80107-6","url":null,"abstract":"<div><p>Several methods of coupling immunoglobulins onto sheep erythrocytes have been examined with a view to demonstrate Semliki-Forest virus by use of a passive hemagglutination test. With the exception of the carbodiimid coupling reaction, most methods could be used to couple goat anti SFV IgG to erythrocytes. Best results were obtained when anti SFV goat IgG was coupled to sheep red blood cells by using 0.25% glutaraldehyde. Sheep red blood cells treated after that method could be used to identify as well as titrate SFV in any given solution. The actual mode of agglutination was made visible by electron microscopy in so far as SFV was found to form dimers of adjacent erythrocytes via a bridge formation. The passive hemagglutination offers considerable advantages compared to other methods such as the direct hemagglutination with goose erythrocytes, as formalin inactivated virus can be detected thereby. The described test therefore offers an additional approach to check the potency of inactivated togavirus vaccines.</p><p>Zusammenfassung</p><p>Verschiedene Methoden zur Kopplung von Anti-Semliki-Forest-Virus (SFV) Immunoglobulin an Hammelerythrozyten wurden im passiven Haemagglutinationstest geprüft. In der Mehrzahl der geprüften Systeme war eine wirkungsvolle Bindung an Hammelerythrozyten erreichbar. Beste Ergebnisse wurden jedoch erreicht, wenn Immunoglobuline mittels Glutaraldehyd (0,25%) an Erythrozyten gekoppelt wurden. Derart beladene Erythrozyten konnten sowohl zur Identifizierung als auch zur Titration von Semliki-Forest-Virus verwendet werden. Mit Hilfe elektronenoptischer Untersuchungen wurde die spezifische Bindung von SFV an Erythrozyten mit der Bildung von Brücken zwischen Erythrozyten sichtbar gemacht. Der passive HA-Test kann zur Erfassung von SFV aus Virussuspensionen ohne Vorbehandlung derselben Verwendung finden. Außerdem kann Formalin-inaktiviertes Virus quantitativ erfaßt werden, welches im aktiven HA-Test nicht nachweisbar ist. Dadurch eröffnet dieser Test möglicherweise einen neuen Weg zur Wirksamkeitsprüfung von Togavirusvakzinen aus inaktivierten Viren.</p></div>","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"246 2","pages":"Pages 141-150"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80107-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79971377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antikörper gegen Rotavirus in der Muttermilch 母乳有轮状病毒抗体
Günther Maass , Christa Barckhaus
{"title":"Antikörper gegen Rotavirus in der Muttermilch","authors":"Günther Maass ,&nbsp;Christa Barckhaus","doi":"10.1016/S0172-5599(80)80066-6","DOIUrl":"10.1016/S0172-5599(80)80066-6","url":null,"abstract":"<div><p>116 human milk specimens taken from 36 women during the first 10 days after delivery were investigated for antibodies against rotavirus by crossimmunoelectrophoresis. Antibodies were detected in 37 specimens from 24 women, the antibody titers proved to be lower than the serum antibody titers. Antibody concentrations in the colostral and transitory milk samples declined continuously during the 10 days after delivery. Women with high serum antibody titers against rotavirus possessed antibodies in their colostrum more frequently than women with low antibody titers. There was no difference between the antibody titers in the sera of the women and the corresponding cord blood.</p></div>","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"246 3","pages":"Pages 294-303"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80066-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91209458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Why are the Killed S. typhi Vaccines Ineffective 灭活的伤寒沙门氏菌疫苗为何无效
Cella Barber
{"title":"Why are the Killed S. typhi Vaccines Ineffective","authors":"Cella Barber","doi":"10.1016/S0172-5599(80)80111-8","DOIUrl":"10.1016/S0172-5599(80)80111-8","url":null,"abstract":"<div><p>The mosaic of proteins synthesized by <em>S. typhi, S. enteritidis</em> and <em>E. coli</em>, induced in immunized rabbits corresponding antibodies that precipitated almost indiscriminately numerous heterologous antigens.</p><p>Antibodies induced against eventual specific antigens could not be identified unless the sera were absorbed with heterologous proteins.</p><p>The comparative immunochemical analysis of the total and absorbed sera proved that the proteins from <em>E. coli</em> are mixed with proteins sharing <em>Salmonella</em> specificities while <em>E. coli</em> proteins are present in the mixtures of proteins isolated from <em>S. enteritidis</em> and <em>S. typhi</em>. The absorption of anti <em>S. typhi</em> sera with proteins from different <em>E. coli</em> serotypes, removed a large amount of antibodies, leaving free for reaction those induced against <em>Salmonellae</em> common proteins.</p><p>The absorption of the anti <em>S. typhi</em> sera with proteins from <em>S. enteritidis</em> eliminated the totality of precipitating antibodies meaning that no specific antibody was induced in the sera of animals immunized with <em>S. typhi</em> proteins.</p><p>In contrast, the <em>S. enteritidis</em> proteins induced antibodies against a specific <em>S. enteritidis</em> protein, in addition to numerous heterologous determinants; the existence of the specific antibody was evident in all the absorbed sera, notwithstanding the eventual relationship with the heterologous absorbing proteins.</p><p>Absorptions of the antisera to proteins from <em>E. coli</em> with proteins from either <em>S. typhi</em> or <em>S. enteritidis</em> removed the antibodies induced against the absorbing proteins leaving free for reactions antibodies for the specific <em>E. coli</em> proteins.</p><p>As the behaviour in vivo of the human pathogen is quite different from that of <em>E. coli</em> or <em>S. enteritidis</em>, the absence of a specific antigen in the material synthesized by <em>S. typhi</em> grown on artificial media provides an explanation for the inefficacy of vaccinations with killed <em>S. typhi</em>.</p><p>Zusammenfassung</p><p>Der Komplex der von <em>S. typhi, S. enteritidis</em> und <em>E. coli</em> synthetisierten Proteine induzierte bei immunisierten Kaninchen entsprechende Antikörper, die gegen zahlreiche heterologe Antigene eine fast unterschiedslose Präzipitation aufwiesen.</p><p>Gegen möglicherweise vorhandene spezifische Antigene induzierte Antikörper ließen sich erst identifizieren, wenn die Seren mit heterologen Proteinen absorbiert wurden.</p><p>Mittels vergleichender immunchemischer Analyse der gesamten und der absorbierten Seren konnte nachgewiesen werden, daß die <em>E. coli</em>-Proteine mit Proteinen gemischt sind, die Spezifitäten mit Salmonella gemeinsam haben, während in den aus <em>S. enteriüdis</em> und <em>S. typhi</em> isolierten Proteingemischen <em>E. coli</em>-Proteine vorhanden sind. Die Absorption von <em>S. typhi</em>-","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"246 2","pages":"Pages 184-190"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80111-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74127093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Untersuchungen über den Verlust von R-Plasmiden bei E. coli und Klebsiella pneumoniae im Verlauf von Bouillonpassagen 有一项研究,证明大肠杆菌和英杆菌有血样失联
N. Dickgiesser
{"title":"Untersuchungen über den Verlust von R-Plasmiden bei E. coli und Klebsiella pneumoniae im Verlauf von Bouillonpassagen","authors":"N. Dickgiesser","doi":"10.1016/S0172-5599(80)80069-1","DOIUrl":"10.1016/S0172-5599(80)80069-1","url":null,"abstract":"<div><p>Plasmid RP1 (= Carb<sup>r</sup>Neo<sup>r</sup>Kana<sup>r</sup>Tetra<sup>r</sup>Amp<sup>r</sup>) or Plasmid R100 (= Tetra<sup>r</sup>Strept<sup>r</sup>Sulf<sup>r</sup>) were transferred on 5 different strains of <em>E. coli</em> and on 3 strains of <em>Kl. pneumoniae</em>. Plasmid RK1 ( = Carb<sup>r</sup>Tet<sup>r</sup>Strept<sup>r</sup>Amp<sup>r</sup>) was transferred on 3 strains of <em>Kl. pneumoniae</em> also. The resulting strains were cultured in 7 passages of Standard-I-Nutrient-Broth (Merck) and Mueller-Hinton-Broth (Becton-Dickinson); 48 colonies were examined for resistance to antibiotics of the different R-Plasmids.</p><p>In <em>E. coli</em> and in <em>Kl. pneumoniae</em> with R-Plasmids RP1 and RK1 no more than 2 colonies without one of several antibiotic resistances after 7 nutrient broth passages were seen. Striking loss of R-Plasmids was seen in <em>Kl. pneumoniae</em> with R-Plasmid R100 after the third passage. The behaviour of strains in Standard-I-Nutrient-Broth and Mueller-Hinton-Broth was not different.</p><p>In conclusion for sensitivity test colonies should be taken only from primary cultures. Furthermore it is recommended to pick up several colonies from one isolated strain for sensitivity test.</p></div>","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"246 3","pages":"Pages 318-328"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80069-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83025629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Antistreptococcal Antibodies, Rheumatoid Factors and Haptoglobin in Apes and Monkeys 类人猿和猴子的抗链球菌抗体、类风湿因子和触珠蛋白
W. Köhler , Eteri K. Djikidse , W.W. Socha , O. Prokop , D. Gerlach , Rosemarie Otto , Elisabeth Balaeva
{"title":"Antistreptococcal Antibodies, Rheumatoid Factors and Haptoglobin in Apes and Monkeys","authors":"W. Köhler ,&nbsp;Eteri K. Djikidse ,&nbsp;W.W. Socha ,&nbsp;O. Prokop ,&nbsp;D. Gerlach ,&nbsp;Rosemarie Otto ,&nbsp;Elisabeth Balaeva","doi":"10.1016/S0172-5599(80)80068-X","DOIUrl":"10.1016/S0172-5599(80)80068-X","url":null,"abstract":"<div><p>Sera of 157 baboons <em>(Papio hamadryas</em> and <em>P. anubis)</em> 21 chimpanzees <em>(Pan troglodytes)</em> five orang utans <em>(Pongo pygmaeus)</em> three mountain gorillas <em>(Gorilla gorilla beringei)</em> and three gibbons <em>(Hylobates lar lar)</em> were examined for the content of antistreptolysin O, antidesoxyribonuclease B, for the presence of rheumatoid factors as well as for the level and type of haptoglobin.</p><p>The mean antistreptolysin O titer (AST) in baboons was 106 ASU ± 18 in dextransulfate absorbed sera (“real” AST) and 182 ASU ± 34 in non-absorbed sera. The mean decrease after absorption was 20% (i.e., 20% inhibitor + 80% antistreptolysin O), a value that is lower than previously found in rhesus monkeys (55%) or in man (40%). Raised values of anti-DNase B were found in two baboons only, and none of the sera of that species displayed presence of rheumatoid factors.</p><p>In chimpanzees, the mean AST was 68 ± 29 in absorbed and 87 ASU ± 57 in non-absorbed sera. Anti-DNase B was raised in three animals, and in two cases the increase was correlated with raised AST. Of 19 chimpanzee sera examined, 13 were found to contain antigammaglobulins (“rheumatoid factors”) the titers of which reached 1:64 or more.</p><p>All primate sera tested so far showed haptoglobin type 1-1 or Hp 1-1-like patterns. The haptoglobin level in chimpanzees and baboons was comparable to that established in man; in rhesus monkey, on the other hand, much lower values (40–62 mg/100ml) or ahaptoglobinemia were observed. The sera of all monkeys and apes tested so far showed a very low (undiluted, or up to 1:10 titer at most) agglutinating activity against T4-antigencarrying streptococci. This is in agreement with our observations made previously which indicated that human or animal sera of haptoglobin type 1-1 agglutinated streptococci to a much lower degree than type Hp 2-2 or type Hp 2-1 sera.</p></div>","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"246 3","pages":"Pages 308-317"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80068-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75673468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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