{"title":"流感病毒对新生Wistar大鼠多瘤病毒诱导的肾和脑肿瘤的抗逆性活性","authors":"G. Noss , G. Stauch","doi":"10.1016/S0172-5599(80)80065-4","DOIUrl":null,"url":null,"abstract":"<div><p>Simultaneous inoculation of newborn Wistar rats with intact A/PR 8/34 (HON1) influenza virus and the S.E. strain of polyoma virus resulted in significant reduction of the rates of both kidney sarcomas and brain tumors in comparison to controls given polyoma virus, only. This antioncogenic activity (AOA) of influenza virus was observed independently whether or not influenza and polyoma virus were injected on different sites or were inoculated as a combined vaccine. Ether-treated A/PR 8/34 influenza virus was found to have also AOA. However, in one experiment a significant AOA was demonstrated with respect to brain tumors, only, and not for the rate of renal sarcomas. In addition, the influenza strain A/Hong Kong/1/68 (H3N2) was found to have AOA.</p></div>","PeriodicalId":101293,"journal":{"name":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","volume":"246 3","pages":"Pages 285-293"},"PeriodicalIF":0.0000,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80065-4","citationCount":"2","resultStr":"{\"title\":\"Antioncogenic Activity of Influenza Virus on Polyoma Virus Induced Renal and Brain Tumors in Newborn Wistar Rats\",\"authors\":\"G. Noss , G. Stauch\",\"doi\":\"10.1016/S0172-5599(80)80065-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Simultaneous inoculation of newborn Wistar rats with intact A/PR 8/34 (HON1) influenza virus and the S.E. strain of polyoma virus resulted in significant reduction of the rates of both kidney sarcomas and brain tumors in comparison to controls given polyoma virus, only. This antioncogenic activity (AOA) of influenza virus was observed independently whether or not influenza and polyoma virus were injected on different sites or were inoculated as a combined vaccine. Ether-treated A/PR 8/34 influenza virus was found to have also AOA. However, in one experiment a significant AOA was demonstrated with respect to brain tumors, only, and not for the rate of renal sarcomas. In addition, the influenza strain A/Hong Kong/1/68 (H3N2) was found to have AOA.</p></div>\",\"PeriodicalId\":101293,\"journal\":{\"name\":\"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie\",\"volume\":\"246 3\",\"pages\":\"Pages 285-293\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1980-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0172-5599(80)80065-4\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0172559980800654\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0172559980800654","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Antioncogenic Activity of Influenza Virus on Polyoma Virus Induced Renal and Brain Tumors in Newborn Wistar Rats
Simultaneous inoculation of newborn Wistar rats with intact A/PR 8/34 (HON1) influenza virus and the S.E. strain of polyoma virus resulted in significant reduction of the rates of both kidney sarcomas and brain tumors in comparison to controls given polyoma virus, only. This antioncogenic activity (AOA) of influenza virus was observed independently whether or not influenza and polyoma virus were injected on different sites or were inoculated as a combined vaccine. Ether-treated A/PR 8/34 influenza virus was found to have also AOA. However, in one experiment a significant AOA was demonstrated with respect to brain tumors, only, and not for the rate of renal sarcomas. In addition, the influenza strain A/Hong Kong/1/68 (H3N2) was found to have AOA.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
