IF 3.7 4区心理学

Stress-The International Journal on the Biology of Stress Pub Date : 2026-12-31 Epub Date: 2026-06-24 DOI: 10.1080/10253890.2026.2684153

Margherita Barbetti, Luca Carnevali, Andrea Sgoifo

{"title":"Transcutaneous auricular vagus nerve stimulation and stress regulation: preclinical insights and unresolved challenges.","authors":"Margherita Barbetti, Luca Carnevali, Andrea Sgoifo","doi":"10.1080/10253890.2026.2684153","DOIUrl":"10.1080/10253890.2026.2684153","url":null,"abstract":"Chronic stress exposure contributes to the onset and maintenance of a wide range of mental and physical disorders. Non-invasive modulation of vagal pathways has received increasing attention as a potential strategy for the prevention and treatment of stress-related conditions, given the central role of the vagus nerve in brain-body communication. By stimulating auricular vagal afferents, transcutaneous auricular vagal nerve stimulation (taVNS) is proposed to engage stress regulatory circuits, with downstream effects that may modulate stress-related physiology. Consistent with this mechanistic rationale, preclinical rodent research has begun investigating the effectiveness of taVNS as a non-invasive approach to mitigate stress-related outcomes. The aim of this narrative review is to summarize this emerging preclinical evidence, focusing on potential mechanisms involving central neural circuits implicated in stress regulation, as well as downstream autonomic function, inflammatory signaling pathways, and gut microbiota composition. Collectively, available studies support taVNS as a multi-system modulator of stress responses acting through interconnected neural, autonomic, immune, and gut-brain pathways. However, preclinical taVNS research remains at an early stage. Major unresolved challenges include the lack of standardized stimulation parameters and insufficient consideration of biological sex as a critical experimental variable. Addressing these limitations will be essential to improve reproducibility and strengthen translational relevance.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"29 1","pages":"2684153"},"PeriodicalIF":3.7,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148310524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interpreting cortisol and testosterone: are they markers of readiness to perform? 解读皮质醇和睾酮：它们是表现准备的标志吗？

IF 3.7 4区心理学

Stress-The International Journal on the Biology of Stress Pub Date : 2026-12-31 Epub Date: 2026-08-31 DOI: 10.1080/10253890.2026.2723347

Benjamin G Serpell, Christian J Cook

{"title":"Interpreting cortisol and testosterone: are they markers of readiness to perform?","authors":"Benjamin G Serpell, Christian J Cook","doi":"10.1080/10253890.2026.2723347","DOIUrl":"10.1080/10253890.2026.2723347","url":null,"abstract":"Readiness in sport is a topic of interest for many coaches, athletes, and performance support staff alike. In the context of hormones, it has been viewed as a response to stress (i.e. increasing free cortisol and testosterone). However, whether a causal relationship exists for cortisol and testosterone with performance remains unclear. Free cortisol and testosterone possibly remain best viewed as relevant biomarkers of the stress response, with this response also being, in part, a proxy measure of readiness. The priming of cortisol and testosterone through exercise, warm-up, or other stimuli to prepare for performance has been a recurring theme amongst research; however, the results in terms of both the magnitude of hormone change and influence on subsequent performance are highly variable. In fact, cortisol and testosterone change in the context of readiness appears individual in nature and are affected by physiology, training status, age, sex, trained state, and individuals' perceptions of both their liking and the magnitude of the stressor. The importance of individuality in this context is poorly understood, and an opportunity exists to undertake research to increase the understanding and application of strategies that may enhance readiness to perform in females and males.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"29 1","pages":"2723347"},"PeriodicalIF":3.7,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148867624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of genes and pathways associated with chronic restraint stress-induced anxiodepressive-like behaviors in female mice by transcriptomic and genome-wide DNA methylation combinational-analysis. 通过转录组学和全基因组DNA甲基化组合分析鉴定雌性小鼠慢性约束应激诱导的焦虑抑郁样行为相关的基因和途径。

IF 3.7 4区心理学

Stress-The International Journal on the Biology of Stress Pub Date : 2026-12-31 Epub Date: 2026-08-31 DOI: 10.1080/10253890.2026.2723356

Ming-Lian Luo, Yi-Heng Li, Yuan-Jian Yang, Xue-Mei Gao

{"title":"Identification of genes and pathways associated with chronic restraint stress-induced anxiodepressive-like behaviors in female mice by transcriptomic and genome-wide DNA methylation combinational-analysis.","authors":"Ming-Lian Luo, Yi-Heng Li, Yuan-Jian Yang, Xue-Mei Gao","doi":"10.1080/10253890.2026.2723356","DOIUrl":"https://doi.org/10.1080/10253890.2026.2723356","url":null,"abstract":"Women are at a higher risk for depression and anxiety than men, yet research into the biological mechanisms and pharmacological treatments for female-specific mental disorders, such as perinatal and perimenopausal depression, remains insufficient. DNA methylation, a key epigenetic modification, has been implicated in the pathogenesis of depression. In this study, we exposed female mice to chronic restraint stress (CRS) for 2 weeks, which induced both depression-like and anxiety-like behaviors. We then collected genomic DNA and total RNA from the medial prefrontal cortex (mPFC), a brain region critically involved in depression pathophysiology, and performed RNA sequencing (RNA-Seq) and whole-genome enzymatic methylation sequencing (EM-seq) to investigate stress-related transcriptional and epigenetic changes. Transcriptomic analysis identified 105 upregulated and 71 downregulated genes in the mPFC of CRS-exposed mice. Notably, CRS increased the expression of genes associated with the complement and coagulation cascades, while downregulating the expression of genes encoding neurotransmitter receptors, their downstream signaling regulators, and markers of neuronal activity. Epigenetic profiling revealed 6,848 hypermethylated and 4,530 hypomethylated regions, with CRS altering both CG- and CHH-type DNA methylation. Integrative analysis uncovered 13 downregulated genes with significant hypermethylation, most of which were implicated in neuronal activity regulation, and 8 upregulated genes with hypomethylation. Our findings suggest that CRS-induced DNA hypermethylation at CG and CHH sites in the female mPFC may contribute to stress-induced transcriptional dysregulation, potentially driving anxiodepressive-like behaviors. These results provide new insights into the epigenetic mechanisms underlying sex-specific stress responses.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"29 1","pages":"2723356"},"PeriodicalIF":3.7,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148867590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differential effects of stress by sex and stress model: the source matters. 性别和压力模型对压力的差异影响：来源问题。

IF 3.7 4区心理学

Stress-The International Journal on the Biology of Stress Pub Date : 2026-12-31 Epub Date: 2026-08-05 DOI: 10.1080/10253890.2026.2712384

P Torres-Carrillo, Y B Vidal-de-la-O, D B Paz-Trejo, L D Ochoa-de-la-Paz, N Trujillo-Gutiérrez, F Sánchez-Flores, H Sánchez-Castillo

{"title":"Differential effects of stress by sex and stress model: the source matters.","authors":"P Torres-Carrillo, Y B Vidal-de-la-O, D B Paz-Trejo, L D Ochoa-de-la-Paz, N Trujillo-Gutiérrez, F Sánchez-Flores, H Sánchez-Castillo","doi":"10.1080/10253890.2026.2712384","DOIUrl":"10.1080/10253890.2026.2712384","url":null,"abstract":"It has been shown that stress is related to survival and adaptation. However, the same adaptive response can become noxious and produce disruptions that are related to the development of different disorders, such as anxiety, depression, post-traumatic stress disorder, etc. These dual effects of stress (positive/negative) could be related to the type of stress, intensity, and recently it has been shown that sex has a major role in the behavioral output. The goal of this study was to characterize the effects of the type of stressor on anxiety-like behaviors, depressive-like behaviors, and spatial and recognition memory. Male and female Wistar rats, 12 weeks old and weighing 200-340 g at the beginning of the experiment were used. The subjects were divided into control, Chronic Unpredictable Stress Battery (CUSB), and Predator Scent Stress (PSS) groups. They were evaluated using the following tests: open field, forced swim, elevated zero maze, saccharin preference, Barnes maze, and novel object recognition tests. The results revealed sex- and stressor-specific behavioral and neuroendocrine profiles, indicating that stress outcomes cannot be generalized without carefully considering the source of stress, the sex/gender of the subject, and other variables relevant to the pathophysiology of stress-related mental illnesses.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"29 1","pages":"2712384"},"PeriodicalIF":3.7,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148674625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of transcutaneous cervical vagus nerve stimulation on autonomic function in posttraumatic stress disorder and opioid use disorder. 经皮颈迷走神经刺激对创伤后应激障碍和阿片类药物使用障碍患者自主神经功能的影响。

IF 3.7 4区心理学

Stress-The International Journal on the Biology of Stress Pub Date : 2026-12-31 Epub Date: 2026-09-04 DOI: 10.1080/10253890.2026.2726826

J Douglas Bremner, Asim H Gazi, Nil Z Gurel, Tamara P Lambert, Matthew T Wittbrodt, Justine W Welsh, Bradley D Pearce, Viola Vaccarino, Amit J Shah, Omer T Inan

{"title":"Effects of transcutaneous cervical vagus nerve stimulation on autonomic function in posttraumatic stress disorder and opioid use disorder.","authors":"J Douglas Bremner, Asim H Gazi, Nil Z Gurel, Tamara P Lambert, Matthew T Wittbrodt, Justine W Welsh, Bradley D Pearce, Viola Vaccarino, Amit J Shah, Omer T Inan","doi":"10.1080/10253890.2026.2726826","DOIUrl":"https://doi.org/10.1080/10253890.2026.2726826","url":null,"abstract":"The vagus nerve has branches that extend to the brain and a number of peripheral organs. Vagus nerve stimulation (VNS) affects autonomic function through enhancement of parasympathetic activity and suppression of sympathetic activity. Because of these effects VNS has a number of potential therapeutic applications. This review focuses on the effects of transcutaneous cervical VNS (tcVNS) on autonomic function in two stress-related psychiatric disorders that are characterized by increased sympathetic function, posttraumatic stress disorder (PTSD) and opioid use disorder (OUD). We have studied the effects of tcVNS on physiology in patients with PTSD and OUD with brain imaging, blood biomarkers, and wearable sensing devices. These studies demonstrated that tcVNS has effects on autonomic tone, cardiovascular function, inflammatory responses, and central brain areas involved in the modulation of emotion, that are favorable in terms of promoting recovery for patients with PTSD and OUD, in particular through effects that mitigate autonomic system dysregulation that underlies the symptomatology of these disorders. The effects of tcVNS on autonomic function and other stress-related circuits and systems show promise for development of interventions for these stress-related disorders that are related to the underlying neurobiology.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"29 1","pages":"2726826"},"PeriodicalIF":3.7,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148892827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allostatic load in psychiatry: a systematic review and meta-analysis. 精神病学中的适应负荷：一项系统回顾和荟萃分析。

IF 3.7 4区心理学

Stress-The International Journal on the Biology of Stress Pub Date : 2026-12-31 Epub Date: 2026-02-21 DOI: 10.1080/10253890.2026.2635367

Sabine Finlay, Riana Marie, Donna Rudd, Brett McDermott, Blazej Misiak, Robert-Paul Juster, Zoltán Sarnyai

{"title":"Allostatic load in psychiatry: a systematic review and meta-analysis.","authors":"Sabine Finlay, Riana Marie, Donna Rudd, Brett McDermott, Blazej Misiak, Robert-Paul Juster, Zoltán Sarnyai","doi":"10.1080/10253890.2026.2635367","DOIUrl":"10.1080/10253890.2026.2635367","url":null,"abstract":"The pathophysiology of psychiatric disorders is complex and involves multiple biological systems. The allostatic load (AL) model offers a framework to capture this multisystem dysregulation by assessing biomarkers that reflect the activity of different physiological systems. This systematic review aimed to summarise current literature on the association between AL and psychiatric disorders. The databases Medline (Ovid), PsycINFO, Ovid Emcare, CINAHL, Cochrane, and Scopus were systematically searched from inception to July 2025. A total of twenty-eight studies were included in the systematic review, and sixteen were eligible for meta-analysis. We found that individuals with a psychiatric disorder demonstrated elevated AL compared to healthy controls (HCs). Furthermore, the meta-analyses revealed an overall standardised mean difference of the between-group meta-analysis, which demonstrated higher AL in individuals with schizophrenia and first-episode psychosis (SMD: 0.97; 95% CI: 0.76, 1.18; p < .0001) compared to HCs. In contrast, no significant difference in AL was observed for individuals with major depressive disorder (SMD: 0.07; 95% CI: -0.23; 0.37; p = 0.67). In conclusion, the AL model may offer a valuable tool for evaluating the impact of chronic stress across various biological systems. This approach can be applied to the early intervention of the core pathophysiology as well as systemic comorbidities that are common among those with psychiatric symptoms.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"29 1","pages":"2635367"},"PeriodicalIF":3.7,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146777111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrodermal signatures of stress during tactical law enforcement training. 战术执法训练中压力的皮肤电特征。

IF 3.7 4区心理学

Stress-The International Journal on the Biology of Stress Pub Date : 2026-12-31 Epub Date: 2026-08-25 DOI: 10.1080/10253890.2026.2723354

Marcelo Bigliassi, Jesse Curtis, Vivian Vu Yasutake, Kevin Acosta, Dawna Bagherian, Robert Laing, Melis Yilmaz Balban

{"title":"Electrodermal signatures of stress during tactical law enforcement training.","authors":"Marcelo Bigliassi, Jesse Curtis, Vivian Vu Yasutake, Kevin Acosta, Dawna Bagherian, Robert Laing, Melis Yilmaz Balban","doi":"10.1080/10253890.2026.2723354","DOIUrl":"10.1080/10253890.2026.2723354","url":null,"abstract":"Law enforcement tactical training places sustained cognitive and emotional demands on recruits, making stress regulation a critical determinant of learning and performance. This study examined EDA as an objective index of stress regulation during standardized law enforcement scenarios. Objectives were to 1) predict individual change in tactical performance from electrodermal dynamics, 2) test whether a breathing-based intervention produces different pre- to post-physiological change than standard training across the full scenario periods, and 3) quantify peri-threat EDA dynamics during threat recognition. Fifty-three recruits completed repeated pre- and post-training evaluations. Continuous EDA was recorded via wearable sensors across four scenarios. Performance change was defined as post-training minus baseline performance scores and modeled using machine learning with repeated 5-fold cross-validation. Random forest models explained 30% of the variance in performance change, and improvers versus non-improvers were classified with 77.1% accuracy, driven primarily by sympathetic energy and phasic amplitude. Whole-scenario analyses showed robust Time effects but no reliable Group or Time × Group effects. In the peri-threat window, onset latency showed a Time × Group interaction (p = .031, d = 0.86), with shorter post-training latency in Controls and stable latency in Experimental. Findings indicate that officer recruit tactical performance can be predicted from electrodermal dynamics measured during scenario-based training, and that performance improvement can be predicted from stress regulation dynamics. Finally, a brief biofeedback-based breathing intervention significantly slowed down the threat-triggered sympathetic arousal. The results support the use of biofeedback-based stress interventions in recruit training to shape autonomic responses and improve tactical performance.","PeriodicalId":51173,"journal":{"name":"Stress-The International Journal on the Biology of Stress","volume":"29 1","pages":"2723354"},"PeriodicalIF":3.7,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148820210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Establishing Normative Anxiety and Depression Levels With PROMIS Parent Proxy Measures. 用PROMIS家长代理量表建立规范的焦虑和抑郁水平。

IF 3 2区心理学

Assessment Pub Date : 2026-12-01 Epub Date: 2025-11-20 DOI: 10.1177/10731911251385766

Zoë Mermin, Kristina R Olson, Natalie M Gallagher

{"title":"Establishing Normative Anxiety and Depression Levels With PROMIS Parent Proxy Measures.","authors":"Zoë Mermin, Kristina R Olson, Natalie M Gallagher","doi":"10.1177/10731911251385766","DOIUrl":"10.1177/10731911251385766","url":null,"abstract":"The PROMIS Parent Proxy Measures for anxiety and depression are brief, validated, and freely available tools for assessing childhood anxiety and depressive symptoms. To improve their interpretability, we recruited a nationally representative sample of U.S. parents of children aged 5-17 (N = 1,213) to report on their child's anxiety and depressive symptoms using the PROMIS v3.0 measures. Our findings largely validate the PROMIS v3.0 scoring system, with means and medians close to 50. However, we observed narrower standard deviations than the published measure, meaning that some youth not flagged by the existing cutoffs could be experiencing meaningful dysfunction (relative to their peers). We also observed strong floor effects, suggesting that these measures do not differentiate among a large group of youth who are not showing anxiety and depression symptoms. In addition, we present norms by age group and gender, noting that differences emerge in adolescence. We recommend the use of the normative values we present in this study, allowing researchers and clinicians to better understand where a given youth falls within the full distribution of American youth.","PeriodicalId":8577,"journal":{"name":"Assessment","volume":" ","pages":"1387-1400"},"PeriodicalIF":3.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145562441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Norming of the NIH Toolbox Cognition Battery Version 3. 规范NIH工具箱认知电池版本3。

IF 3 2区心理学

Assessment Pub Date : 2026-12-01 Epub Date: 2025-11-15 DOI: 10.1177/10731911251386277

Emily H Ho, Y Catherine Han, Erica M LaForte, Aaron J Kaat, Elizabeth M Dworak, Berivan Ece, Lihua Yao, James B Olsen, Richard C Gershon

{"title":"Norming of the NIH Toolbox Cognition Battery Version 3.","authors":"Emily H Ho, Y Catherine Han, Erica M LaForte, Aaron J Kaat, Elizabeth M Dworak, Berivan Ece, Lihua Yao, James B Olsen, Richard C Gershon","doi":"10.1177/10731911251386277","DOIUrl":"10.1177/10731911251386277","url":null,"abstract":"The NIH Toolbox® for Assessment of Neurological and Behavioral Function Cognition Battery (NIHTB-CB) is a brief neuropsychological assessment tool created as part of the NIH Neuroscience Blueprint. Since its inception, NIHTB-CB has been widely used in a variety of clinical and research settings, including large-scale epidemiological studies. The NIHTB-CB was recently updated and re-normed to Version 3 (V3). We describe the approach to establish normative reference values. The NIHTB-CB tests were administered to a large English-speaking sample of n = 3,904 (average age = 25.7 years, 52.1% female) individuals from the U.S. population, stratified by age, race and ethnicity, sex assigned at birth, and education level within the four U.S. census regions. Normative data were raked via iterative proportional fitting (e.g., by sex assigned at birth, race, ethnicity, and educational attainment nested within geographic region) to derive sampling weights that match the demographic proportions from the U.S. Census targets. Through regression-based continuous norming and bootstrap techniques, age-adjusted and age-and-education-adjusted normative scores were created for individual measure-level and composite scores.","PeriodicalId":8577,"journal":{"name":"Assessment","volume":" ","pages":"1401-1411"},"PeriodicalIF":3.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12879375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145522933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the Best Structure to Conceptualize and Assess Multidimensional Schizotypy. 探讨概念化和评估多维分裂型的最佳结构。

IF 3 2区心理学

Assessment Pub Date : 2026-12-01 Epub Date: 2025-10-24 DOI: 10.1177/10731911251381600

Alysia M Berglund, Laura M Hernández, Kathryn C Kemp, George M Gross, Jessica A Kaczorowski, Christopher J Burgin, Neus Barrantes-Vidal, Thomas R Kwapil

{"title":"Investigating the Best Structure to Conceptualize and Assess Multidimensional Schizotypy.","authors":"Alysia M Berglund, Laura M Hernández, Kathryn C Kemp, George M Gross, Jessica A Kaczorowski, Christopher J Burgin, Neus Barrantes-Vidal, Thomas R Kwapil","doi":"10.1177/10731911251381600","DOIUrl":"10.1177/10731911251381600","url":null,"abstract":"Schizotypy offers a useful and unifying construct for understanding schizophrenia-spectrum psychopathology. Current conceptualizations and findings support a three-factor model of schizotypy consisting of positive, negative, and disorganized dimensions. However, recent studies have suggested four- and five-factor structures. The present study compared and examined the extent to which each factor model predicted interview and questionnaire outcome measures. Confirmatory factor analysis (CFA) and exploratory structural equation models (ESEM) were employed to compare the three-factor model with five competing models using the items from the Multidimensional Schizotypy Scale (MSS) in 10,814 adults. We subsequently compared the supported models in terms of the prediction of interview (n = 339) and questionnaire assessed symptoms (n of 1,342 to 1,430) using hierarchical linear regressions. The three-, four-, and five-factor models provided the best fit. However, the four-and five-factor models generally did not improve the prediction of outcome measures, although exploratory analyses suggest some potential value for the negative schizotypy subfactor model. The present findings, along with previous validation studies, support positive, negative, and disorganized factors. Ultimately, we recommend that alternative factor and subfactor models of schizotypy should be developed from conceptual, not atheoretical-exploratory approaches.","PeriodicalId":8577,"journal":{"name":"Assessment","volume":" ","pages":"1266-1281"},"PeriodicalIF":3.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145353702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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