Neuropsychologia最新文献

Functional neural oscillatory activities reveal the impact of attentional instructions on speech auditory feedback control 功能性神经振荡活动揭示了注意指令对言语听觉反馈控制的影响

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-06-10 DOI: 10.1016/j.neuropsychologia.2025.109202

Yilun Zhang , Kimaya Sarmukadam , Vahid Nejati , Roozbeh Behroozmand

{"title":"Functional neural oscillatory activities reveal the impact of attentional instructions on speech auditory feedback control","authors":"Yilun Zhang , Kimaya Sarmukadam , Vahid Nejati , Roozbeh Behroozmand","doi":"10.1016/j.neuropsychologia.2025.109202","DOIUrl":"10.1016/j.neuropsychologia.2025.109202","url":null,"abstract":"<div><div>Speech production relies on precise integrations between vocal and auditory feedback mechanisms for fluent verbal communication. This study investigated how explicit attentional instructions influence speech auditory feedback control. A total of forty-three participants performed speech vowel vocalizations while receiving brief (200 ms) and randomized pitch shifts at ±100 cents magnitude in their auditory feedback during concurrent electroencephalography (EEG) recordings. Twenty-one participants were randomly assigned to an attentional-instruction group and were instructed to focus their attention on detecting pitch-shift stimuli via pressing a button whereas no such instructions were provided for the remaining twenty-two participants in the no-instruction group. Behavioral data revealed a significantly smaller peak magnitude of vocal compensation responses to auditory feedback alterations in the attentional-instruction compared with no-instruction group, suggesting an attentional modulation of the speech motor control mechanisms. Time-frequency analyses of EEG data showed a significantly stronger desynchronization of the high-beta band (20–30 Hz) neural activities for the attentional-instruction group, indicating enhanced audio-vocal integration when participants attentively monitored their speech feedback. In addition, we found that the accuracy of button-press responses for detecting pitch shifts positively correlated with the alpha and beta band power (8–30 Hz) while compensation magnitude positively correlated only with the gamma band power (30–80 Hz). These findings provide new insights into the effects of attentional instruction on the neural and behavioral correlates of speech motor control, emphasizing its application as a viable tool for targeted treatment of speech disorders in clinical populations.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"216 ","pages":"Article 109202"},"PeriodicalIF":2.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144262394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemispheric laterality in neural processing of speech and non-speech temporal information on multiple timescales 多时间尺度上言语和非言语时间信息的神经加工中的半球偏侧性

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-06-05 DOI: 10.1016/j.neuropsychologia.2025.109199

Shunsuke Tamura , Hidehiko Okamoto

{"title":"Hemispheric laterality in neural processing of speech and non-speech temporal information on multiple timescales","authors":"Shunsuke Tamura , Hidehiko Okamoto","doi":"10.1016/j.neuropsychologia.2025.109199","DOIUrl":"10.1016/j.neuropsychologia.2025.109199","url":null,"abstract":"<div><div>Numerous studies have investigated hemispheric laterality of multi-band neural oscillatory activities in response to speech temporal information, but their speech- and language-specificity remain elusive. In the present study, using magnetoencephalography, we examined laterality patterns of theta (4–8 Hz) and high gamma-band (more than 80 Hz) activities phase-locked to temporal envelope and fine structure, respectively, of speech and non-speech stimuli. Monotone speech (MS) with a fundamental frequency of 80 Hz and its backward sound (bMS) were used as speech stimuli. We also used noise-vocoded speech (NVS), which has the same temporal envelope as MS, but no fine structure, and its backward sound (bNVS) to investigate the effects of temporal fine structure on multi-band oscillatory activities. A 5 Hz amplitude-modulated 80 Hz click-train (AMC) and noise (AMN) were used as non-speech stimuli. We confirmed that speech and non-speech stimuli with fine structure (MS, bMS, and AMC) caused stronger 5 Hz and 80 Hz activities in the right than in the left hemisphere. Regarding the language specificity, we found that the 5 Hz power in the right hemisphere decreased in backward compared to forward speech conditions (MS > bMS and NVS > bNVS). These results suggest that the right hemisphere plays an important role in auditory processing of temporal fine structure through high gamma-band activity in common with speech and non-speech sounds. In addition, theta-band activity phase-locked to the temporal envelope in the right hemisphere contributes to recognition of speech signals.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"216 ","pages":"Article 109199"},"PeriodicalIF":2.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144231626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conflict resolution and response inhibition: A simultaneous EEG-EMG-pupillometry study 冲突解决和反应抑制：同时进行的脑电图-肌电-瞳孔测量研究。

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-06-04 DOI: 10.1016/j.neuropsychologia.2025.109192

Carsten Bundt , Liisa Raud , Christina Thunberg , René J. Huster

{"title":"Conflict resolution and response inhibition: A simultaneous EEG-EMG-pupillometry study","authors":"Carsten Bundt , Liisa Raud , Christina Thunberg , René J. Huster","doi":"10.1016/j.neuropsychologia.2025.109192","DOIUrl":"10.1016/j.neuropsychologia.2025.109192","url":null,"abstract":"<div><div>Inhibition in cognitive control has many implications. Behaviorally, the stop signal task is supposedly capturing inhibition of already initiated responses (response inhibition). In contrast, the flanker paradigm supposedly captures the inhibition of several competing responses (competitive inhibition). As the neural mechanisms for these behavioral phenomena are not clear, it begs the question of whether both response inhibition and competitive inhibition draw from a similar inhibitory resource pool and to what extent they might interact.</div><div>In the current study, the potential interplay between inhibitory mechanisms was investigated in a combined stop-signal flanker task where (in-)congruent flankers were occasionally followed by stop signals. A multimodal task-setup was implemented allowing for examination of behavior, electromyography (EMG), electroencephalography (EEG), and pupillometry to assess different inhibition-related outcome measures.</div><div>Estimates of response inhibition speed (stop-signal reaction times; SSRTs) indicated an interaction with competitive inhibition, where stopping was faster in incongruent compared to congruent stop conditions. However, this was likely driven by differences at the short stop signal delays, which are susceptible to horse race model violations. Moreover, this interaction was not evident in physiological measures: neither stop-related EMG, EEG nor pupillometry measures showed such congruency modulations. Exploratory analyses showed that a larger pupillometry congruency effect was negatively associated with the congruency effect in SSRTs, suggesting that pupil dilation as a proxy for NE-LC activity might be linked to increased allocation of cognitive control. Taken together, our results do not provide clear evidence for an interaction between response inhibition and competitive inhibition.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"216 ","pages":"Article 109192"},"PeriodicalIF":2.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A new behavioural intervention to enhance memory in older people-evening autobiographical recall. 一种增强老年人记忆的新行为干预——夜间自传体回忆。

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-06-04 DOI: 10.1016/j.neuropsychologia.2025.109191

J Blackman, V Gabb, D Woodstoke, H Morrison, M Taylor, N Turner, H Li, B Biswas, A Heslegrave, A Whone, L Mickes, E Coulthard

{"title":"A new behavioural intervention to enhance memory in older people-evening autobiographical recall.","authors":"J Blackman, V Gabb, D Woodstoke, H Morrison, M Taylor, N Turner, H Li, B Biswas, A Heslegrave, A Whone, L Mickes, E Coulthard","doi":"10.1016/j.neuropsychologia.2025.109191","DOIUrl":"https://doi.org/10.1016/j.neuropsychologia.2025.109191","url":null,"abstract":"<p><p>Episodic memory deteriorates with age and in Alzheimer's Disease (AD). Interventions to enhance memory in these cohorts are limited and associated with disadvantages inherent in pharmaceuticals and in the cost/availability of formal cognitive enhancement programmes. Here we tested whether an autobiographical retrieval task could enhance performance in a separate word-list recognition task. The RESTED-AD Study (Remote Evaluation of Sleep To enhance understanding in Early Dementia) was a cohort study comprising individuals with AD MCI/early dementia and age-matched healthy controls (HC). Participants completed a word recognition task twice, with learning and test phases separated by sleep. On one occasion, participants wrote down 5 autobiographical events occurring in their day before bedtime (Autobiographical Condition). Episodic memory accuracy was compared in the Autobiographical vs Standard Condition. Sleep was recorded utilising a home-based EEG headband. Twenty-six participants (AD = 8, HC = 18, 5 Female) had mean (SD) age of 70.0 (6.6), and Montreal Cognitive Assessment Score of 26.1 (2.4). Full cohort accuracy score increased in the Autobiographical Condition [% Mean (SD) Standard = 82.0 (11.0), Autobiographical = 86.4 (8.1), Cohen's D = 0.452, p = 0.024]. This relationship maintained after correction for confounding variables and task order. After False Discovery correction, no evidence was found to support sleep-mediated mechanisms. Autobiographical memory evocation was positively associated with recognition memory performance in older adults and individuals with AD. As an intervention with no foreseeable risks, replication of this finding and further work to establish underlying mechanisms is warranted.</p>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":" ","pages":"109191"},"PeriodicalIF":2.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retrieving the spatial layout of medium-scale geographical maps through distributional semantics. 基于分布语义的中比例尺地形图空间布局检索。

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-06-02 DOI: 10.1016/j.neuropsychologia.2025.109190

Giorgia Anceresi, Daniele Gatti, Tomaso Vecchi, Marco Marelli, Luca Rinaldi

{"title":"Retrieving the spatial layout of medium-scale geographical maps through distributional semantics.","authors":"Giorgia Anceresi, Daniele Gatti, Tomaso Vecchi, Marco Marelli, Luca Rinaldi","doi":"10.1016/j.neuropsychologia.2025.109190","DOIUrl":"https://doi.org/10.1016/j.neuropsychologia.2025.109190","url":null,"abstract":"<p><p>Recent evidence has indicated that spatial representations, such as large-scale geographical maps, can be retrieved from natural language alone through cognitively plausible distributional-semantic models, which capture word meanings through contextual relationship (i.e., non-spatial associative-learning mechanisms) in large linguistic corpora. Here, we demonstrate that spatial information can be extracted from purely linguistic data even at the medium-scale level (e.g., landmarks within a city). Our results indeed show that different spatial representations (i.e., with information encoded either in terms of relative spatial distances or absolute locations defined by coordinate axes) of the underground maps of five European cities can be retrieved from natural language. Furthermore, by selectively focusing on the London tube, we show that linguistic data align effectively with both geographical and schematic visual maps. These findings contribute to a growing body of research that challenges the traditional view of cognitive maps as primarily relying on specialized spatial computations and highlight the importance of non-spatial associative-learning mechanisms within the linguistic environment in the setting of spatial representations.</p>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":" ","pages":"109190"},"PeriodicalIF":2.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of neuromodulation with tDCS on developmental dyslexia: A randomized, double-blind, controlled clinical trial 神经调节与tDCS对发展性阅读障碍的有效性：一项随机、双盲、对照临床试验

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-06-02 DOI: 10.1016/j.neuropsychologia.2025.109189

Mehdi Rezaei, Fatemeh Peigodari, Mohammad Reza Asadi Younesi

{"title":"Effectiveness of neuromodulation with tDCS on developmental dyslexia: A randomized, double-blind, controlled clinical trial","authors":"Mehdi Rezaei, Fatemeh Peigodari, Mohammad Reza Asadi Younesi","doi":"10.1016/j.neuropsychologia.2025.109189","DOIUrl":"10.1016/j.neuropsychologia.2025.109189","url":null,"abstract":"<div><div>Regarding the utility of transcranial direct current stimulation (tDCS) in dyslexic children, the results are promising but also ambiguous. The present study aimed to investigate whether tDCS would enhance the reading skills of dyslexic children and whether the effect is long-lasting.</div><div>A randomized, double-blind, sham-controlled clinical trial was used. Forty children with developmental dyslexia received twelve 20-min left anodal right cathodal tDCS set at 1 mA over the temporo-parietal cortex. Reading tasks (low and high-frequency words, non-words, irregular words, and text reading errors) were used as outcome measures and collected before treatment, after treatment, and one month after intervention. The safety of tDCS was also evaluated. In the active tDCS, the mean scores of low-frequency and non-word reading, and text reading errors were significantly improved immediately and one month after the treatment, compared to the sham tDCS. Concerning high-frequency and irregular word reading, there were no significant differences between the active and sham tDCS at post-test and follow-up. Our findings might provide a framework to facilitate behavioral rehabilitation in children with developmental dyslexia.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"216 ","pages":"Article 109189"},"PeriodicalIF":2.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144204458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The optimisation of functional brain network dynamics when learning to perform complex tasks 学习执行复杂任务时功能性脑网络动力学的优化。

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-30 DOI: 10.1016/j.neuropsychologia.2025.109188

Beth L. Parkin , Richard E. Daws , Gregory Scott , Eyal Soreq , Robert Leech , Peter J. Hellyer , Adam Hampshire

{"title":"The optimisation of functional brain network dynamics when learning to perform complex tasks","authors":"Beth L. Parkin , Richard E. Daws , Gregory Scott , Eyal Soreq , Robert Leech , Peter J. Hellyer , Adam Hampshire","doi":"10.1016/j.neuropsychologia.2025.109188","DOIUrl":"10.1016/j.neuropsychologia.2025.109188","url":null,"abstract":"<div><div>We present two novel self-ordered switching (SOS) fMRI paradigms designed to investigate how brain networks facilitate the establishment of structured human behaviour during the learning of complex tasks with multiple goals. In study 1, SOS was performed with minimal pretraining and detailed feedback to capture the learning process, while in study 2 substantial pretraining and minimal feedback were used as a control where the potential for ongoing optimisation of behaviour is reduced. Study 1 revealed changes in the learning process characterised by a decrease in task-switching frequency, resulting in superior task performance for individuals who minimised switch frequency and ordered their behaviour in simple structured routines. Additionally, with practice, multiple-demand cortex activation became less responsive, and the default mode network became more responsive when performing discrimination trials. Strikingly, the opposite pattern was observed for SOS events, with multiple-demand cortex activation becoming more responsive and default mode network activation becoming less responsive with practice. These neural changes correlated with the degree of structure of behavioural routines. The neural signatures of learning were less evident in study 2, where the task was practiced prior to entering the scanner. Our studies demonstrate that the default mode network and multiple demand cortex complement each other when people learn to perform complex tasks by becoming differentially fine-tuned to routine trial demands vs. executive-switching demands.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"216 ","pages":"Article 109188"},"PeriodicalIF":2.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

To predict or not to predict: The role of context constraint and truth-value in negation processing. 预测与不预测：情境约束与真值在否定加工中的作用。

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-29 DOI: 10.1016/j.neuropsychologia.2025.109167

Maria Spychalska, Viviana Haase, Markus Werning

{"title":"To predict or not to predict: The role of context constraint and truth-value in negation processing.","authors":"Maria Spychalska, Viviana Haase, Markus Werning","doi":"10.1016/j.neuropsychologia.2025.109167","DOIUrl":"https://doi.org/10.1016/j.neuropsychologia.2025.109167","url":null,"abstract":"<p><p>Studies on negation processing often report a Polarity by Truth interaction: False affirmative sentences show longer response times and larger N400 ERPs relative to true affirmative sentences, while for negative sentences the effect of truth-value is typically reversed. This interaction has repeatedly been linked to variations in lexical associations, predictability, or to the need of constructing two subsequent mental representations during the comprehension of negative sentences. In five ERP experiments, employing a picture-sentence verification paradigm, we investigate how negation, truth and predictability interact in sentence processing. Predictability was manipulated by varying the number of alternative sentence continuations provided by the context to make it equivalent for both sentence polarities. For both sentence polarities, true sentences yielded a smaller N400 response in the strongly constraining context, where the processor could form a unique prediction, relative to the weakly constraining context, where no clear prediction could be made. For false sentences, the effect of context was reversed for both sentence polarities. Furthermore, the effect of Truth was dependent on the predictability rather than sentence polarity: Both affirmative and negative sentences showed the same direction of the effect of Truth, i.e., a larger N400 for false rather than true sentences in the strongly constraining context, and a reversed effect in the in the weakly constraining context, although differences in the size of these effects between the two polarities were apparent. In addition, we observe a long lasting positivity effect for negation, in both context conditions, for both truth-values and across all five experiments, which is discussed in terms of inhibition mechanisms caused by negation.</p>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":" ","pages":"109167"},"PeriodicalIF":2.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatial and feature-selective attention interact to drive selective coding in frontoparietal cortex 空间和特征选择性注意相互作用，驱动选择性编码在额顶叶皮层。

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-21 DOI: 10.1016/j.neuropsychologia.2025.109172

Nadene Dermody , Romy Lorenz , Erin Goddard , Arno Villringer , Alexandra Woolgar

{"title":"Spatial and feature-selective attention interact to drive selective coding in frontoparietal cortex","authors":"Nadene Dermody , Romy Lorenz , Erin Goddard , Arno Villringer , Alexandra Woolgar","doi":"10.1016/j.neuropsychologia.2025.109172","DOIUrl":"10.1016/j.neuropsychologia.2025.109172","url":null,"abstract":"<div><div>Attention enables the selective processing of relevant information. Two types of selective attention, spatial and feature-selective attention, have separable neural effects but in real life are often used together. Here, we asked how these types of attention interact to affect information coding in a frontoparietal ‘multiple-demand’ (MD) network, essential for attentional control. Using functional magnetic resonance imaging (fMRI) with multivariate pattern analysis, we examined how covert attention to object features (colour or shape) and spatial locations (left or right) influences coding of task-related stimulus information. We found that spatial and feature-selective attention interacted multiplicatively on information coding in MD and visual regions, such that there was above-chance decoding of the attended feature of the attended object and no detectable coding of visually equivalent but behaviourally irrelevant aspects of the visual display. The attended information had a multidimensional neural representation, with stimulus information (e.g., colour) and discrimination difficulty (distance from the categorical decision boundary) reflected in separate dimensions. Rather than boosting processing of whole objects or relevant features across space, our results suggest neural activity reflects precise tuning to relevant information, indicating a highly selective control process that codes behaviourally relevant information across multiple dimensions.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"216 ","pages":"Article 109172"},"PeriodicalIF":2.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cortical visual processing differences in myopia and blur 近视和模糊的皮层视觉加工差异

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-20 DOI: 10.1016/j.neuropsychologia.2025.109180

Katia Steinfeld , Micah M. Murray

{"title":"Cortical visual processing differences in myopia and blur","authors":"Katia Steinfeld , Micah M. Murray","doi":"10.1016/j.neuropsychologia.2025.109180","DOIUrl":"10.1016/j.neuropsychologia.2025.109180","url":null,"abstract":"<div><div>Myopia is projected to impact over 50 % of the global population by 2050. Despite links to long-lasting anatomical changes in visual cortices, little is known of potential consequences of myopia on visual brain functions, such as visual completion. We hypothesized that adults suffering from moderate myopia process attentionally demanding visual stimuli under optical blur differently than emmetropic adults. Non myopes (<em>N</em> = 12) and low-to-mild myopes <em>(N</em> = 13) were tested under −3 diopters of lens-induced blur. Participants performed an illusory contour discrimination task while 128-channel EEG was recorded. Each trial also included an intervening, task-irrelevant dartboard stimulus. Visual evoked potentials (VEPs) to the illusory contour (IC), no contour (NC), and dartboard stimuli were analyzed using an electrical neuroimaging framework. We provide evidence for cortical processing differences between non myopes and mild myopes at 218–280ms post-stimulus during visual completion, but not during viewing of dartboards. These differences stemmed from topographic modulations, indicative of the engagement of distinct networks of brain regions that were localized to medial portions of the occipital pole. Moreover, the predominant VEP topography during this time period both correlated with extent of refractive error, and also was an excellent classifier of myopia vs. emmetropia. By contrast, our analyses provided no evidence for differences in visual completion processes between groups. To our knowledge, this is the first study of myopia pairing high-density EEG and a behavioral task. Collectively, this pattern of findings supports a model of myopia wherein low-level visual cortices are impacted at relatively late post-stimulus processing stages.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"215 ","pages":"Article 109180"},"PeriodicalIF":2.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144115387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0