Neuropsychologia最新文献

Emotion recognition, symptoms of depression, and fluid intelligence after frontal lobe lesions. 额叶损伤后的情绪识别、抑郁症状和流体智力。

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-13 DOI: 10.1016/j.neuropsychologia.2025.109170

Fionnuala C Murphy, Nadene Dermody, Peter Watson, Sophie K Scott, Andrew J Calder, Polly V Peers, Tom Manly

{"title":"Emotion recognition, symptoms of depression, and fluid intelligence after frontal lobe lesions.","authors":"Fionnuala C Murphy, Nadene Dermody, Peter Watson, Sophie K Scott, Andrew J Calder, Polly V Peers, Tom Manly","doi":"10.1016/j.neuropsychologia.2025.109170","DOIUrl":"https://doi.org/10.1016/j.neuropsychologia.2025.109170","url":null,"abstract":"<p><p>Frontal lobe lesions have been associated with executive impairments and changes in emotional/social function. Empirical studies using emotion recognition tasks in people with frontal lesions have indeed reported impairments that are predominantly associated with medial lesions. However, work has also identified a fronto-parietal 'multiple demand' (MD) network that is engaged in a wide variety of cognitive tasks. Previous studies have shown that fluid intelligence (IQ) scores, treated as a marker of MD function, completely account for deficits in some, but not all, tests of putatively separate executive functions. Here, a group of 39 participants with frontal lesions showed significant impairments (relative to age, sex and premorbid IQ-matched controls) on a measure of fluid IQ and 4 emotion recognition tasks. They also had higher levels of depression symptoms. Depression symptoms did not account for emotion task impairment. Fluid IQ completely accounted for the impairments in one 'emotion task' of inferring the emotion likely to be experienced in each of a series of vignettes. However, whilst fluid IQ was correlated with the other emotion measures (tests of categorising emotional expression from faces, eyes, and non-verbal vocalisations), significant variance was left unexplained. The significant intercorrelations between these residual scores was suggestive of a common 'non-fluid IQ' factor that may have an association with left lateral frontal lesions. The results are discussed in terms of the importance of identifying common general cognitive influences on tests of ostensibly specific functions in clinical assessments and research studies.</p>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":" ","pages":"109170"},"PeriodicalIF":2.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Do eye movements in REM sleep play a role in overnight emotional processing? 快速眼动睡眠中的眼动在夜间情绪处理中起作用吗？

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-12 DOI: 10.1016/j.neuropsychologia.2025.109169

Kyrillos M. Meshreky, Penelope A. Lewis

{"title":"Do eye movements in REM sleep play a role in overnight emotional processing?","authors":"Kyrillos M. Meshreky, Penelope A. Lewis","doi":"10.1016/j.neuropsychologia.2025.109169","DOIUrl":"10.1016/j.neuropsychologia.2025.109169","url":null,"abstract":"<div><div>Eye movements (EMs) are a defining feature of rapid eye movement (REM) sleep, yet we are still not clear why they happen. A few hypotheses attempt to explain the possible underlying mechanisms. However, a clear understanding of their functional significance remains lacking. Interestingly, there is an EM component in Eye Movement Desensitization and Reprocessing (EMDR) therapy, that is approved for post-traumatic stress disorder (PTSD). The developer of EMDR, Francine Shapiro described the technique as mimicry of REM. Robert Stickgold built on this by proposing a putative neurobiological model in which the repeated eye movements in EMDR initiate brainstem REM-like mechanisms. In this article, we combine Stickgold's model with the results of a study which showed that alternating bilateral visual stimulation in mice yielded sustained increases in the activities of the Superior Colliculus (SC) and mediodorsal thalamus (MD) which suppressed the activity of basolateral amygdala. We pose a hypothetical question: could EMs during REM sleep similarly inhibit amygdala activity through the SC-MD pathway? And could this be part of the affective modulation mechanisms characteristic of REM sleep?</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"215 ","pages":"Article 109169"},"PeriodicalIF":2.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143947399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reduced mind-wandering and fewer depressive symptoms associated with damage to the medial prefrontal cortex and default mode network 减少走神和减少抑郁症状与内侧前额叶皮层和默认模式网络的损伤有关

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-09 DOI: 10.1016/j.neuropsychologia.2025.109168

Carissa L. Philippi , Joel Bruss , Carrie Brandauer , Nicholas T. Trapp , Daniel Tranel , Aaron D. Boes

{"title":"Reduced mind-wandering and fewer depressive symptoms associated with damage to the medial prefrontal cortex and default mode network","authors":"Carissa L. Philippi , Joel Bruss , Carrie Brandauer , Nicholas T. Trapp , Daniel Tranel , Aaron D. Boes","doi":"10.1016/j.neuropsychologia.2025.109168","DOIUrl":"10.1016/j.neuropsychologia.2025.109168","url":null,"abstract":"<div><div>Depressive disorders have been consistently associated with elevated levels of mind-wandering and self-focused negative rumination. Separate tracks of research have implicated brain structures within the default mode network (DMN) in both mind-wandering and depression. In this study, we hypothesized that diminished mind-wandering and fewer depressive symptoms would co-occur in individuals with damage to the DMN. To test this hypothesis, we used a k-means clustering algorithm to identify a target group of patients with reduced mind-wandering and fewer depressive symptoms relative to brain-damaged comparison subjects (<em>n</em> = 37 of 68; <em>ps</em> < .001). The anatomical localization of lesions for this target group was predominantly within the medial prefrontal cortex (mPFC). Structural and functional lesion network mapping results revealed that lesions of the target group had significantly greater connectivity with DMN and limbic regions. Taken together, these results suggest that brain injury affecting the mPFC and DMN is associated with both reduced mind-wandering and fewer depressive symptoms. Further investigation of neuroanatomical substrates that mediate a causal relationship between mind-wandering and mood may facilitate the identification of new therapeutic targets for neuromodulation in patients with disorders characterized by maladaptive mind-wandering, such as rumination.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"214 ","pages":"Article 109168"},"PeriodicalIF":2.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shared neural correlates of interference control and response inhibition in adolescence and young adulthood. 青春期和青年期干扰控制和反应抑制的共享神经关联。

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-08 DOI: 10.1016/j.neuropsychologia.2025.109166

Lucy R J Palmer, Denis Mareschal, Iroise Dumontheil

{"title":"Shared neural correlates of interference control and response inhibition in adolescence and young adulthood.","authors":"Lucy R J Palmer, Denis Mareschal, Iroise Dumontheil","doi":"10.1016/j.neuropsychologia.2025.109166","DOIUrl":"https://doi.org/10.1016/j.neuropsychologia.2025.109166","url":null,"abstract":"<p><p>Inhibitory control (IC) is the ability to inhibit dominant or automatic behaviours, responses or thoughts, to allow for the selection of appropriate goal-directed responses. IC is a core executive function and has been associated with specific brain regions, such as the right inferior frontal gyrus (IFG) but also with a broader fronto-parietal network similar to the multi-demand network, which is thought to support the elaboration and maintenance of structured mental programs across a range of tasks. Here, functional magnetic resonance imaging data were collected from different IC tasks within the same participants to investigate similarities and differences in brain activation between tasks and age groups. Adolescents (11-15 years-old, n = 34) and adults (18-26, n = 33) completed a numerical Stroop task and simple and complex Go/No-go (GNG) block-design tasks. Univariate analyses showed large overlapping fronto-parietal activation in the Stroop and complex GNG tasks, with more limited activation in the simple GNG task. When compared to adolescents, adults showed greater increases in activation in the right IFG in the Stroop task and in temporo-parietal and precentral clusters in the complex GNG task. High multivariate similarity was observed across fronto-parietal regions between complex GNG and Stroop tasks, and between simple and complex GNG tasks, but was much lower between Stroop and simple GNG tasks. Adults showed greater similarity between complex GNG and Stroop tasks, suggesting increased reliance on shared neural processes across tasks, rather than increased specialisation of brain networks to specific aspects of IC over development.</p>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":" ","pages":"109166"},"PeriodicalIF":2.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neural and Perceptual Adaptations in Bilateral Macular Degeneration: An Integrative Review. 双侧黄斑变性的神经和知觉适应：综合综述。

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-07 DOI: 10.1016/j.neuropsychologia.2025.109165

Giulio Contemori, Jade Guenot, Benoit R Cottereau, Yves Trotter, Luca Battaglini, Marco Bertamini

{"title":"Neural and Perceptual Adaptations in Bilateral Macular Degeneration: An Integrative Review.","authors":"Giulio Contemori, Jade Guenot, Benoit R Cottereau, Yves Trotter, Luca Battaglini, Marco Bertamini","doi":"10.1016/j.neuropsychologia.2025.109165","DOIUrl":"https://doi.org/10.1016/j.neuropsychologia.2025.109165","url":null,"abstract":"<p><p>Bilateral age-related macular degeneration (AMD) results in central vision loss, affecting the fovea-associated cortical regions. This review examines neuroimaging and psychophysical evidence of spontaneous neural adaptation in acquired bilateral central scotoma. Early visual brain areas show reduced cortical thickness and axonal integrity due to postsynaptic (anterograde) degeneration. Contrary to animal models, evidence for spontaneous adaptation in the primary visual cortex (V1) is limited. Activity in the lesion projection zone (LPZ), previously seen as extensive cortical remapping, may result from non-retinotopic peripheral-to-foveal feedback, sharing substrates with healthy retinal feedforward processes. Preferred retinal loci (PRLs) are influenced more by location and task than by residual vision quality. Reduced lateral masking in the PRL may reflect decreased contrast sensitivity from retinal damage, rather than genuine adaptive mechanisms. Weakened crowding in the PRL is explained by transient adaptation in healthy subjects to artificial scotomas, not by long-term plasticity. Higher visual areas may show compensatory mechanisms enhancing complex tasks like symmetry, face, and motion discrimination. Leveraging spontaneous adaptation through perceptual learning-based treatments can preserve residual visual abilities. Because of limited evidence for spontaneous reorganization in AMD, behavioural training and emerging techniques are crucial for optimal treatment efficacy.</p>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":" ","pages":"109165"},"PeriodicalIF":2.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Category-biased patches encircle core domain-general regions in the human lateral prefrontal cortex 类别偏倚斑块环绕核心域一般区域在人类外侧前额皮质

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-07 DOI: 10.1016/j.neuropsychologia.2025.109164

Moataz Assem , Sneha Shashidhara , Matthew Glasser , John Duncan

{"title":"Category-biased patches encircle core domain-general regions in the human lateral prefrontal cortex","authors":"Moataz Assem , Sneha Shashidhara , Matthew Glasser , John Duncan","doi":"10.1016/j.neuropsychologia.2025.109164","DOIUrl":"10.1016/j.neuropsychologia.2025.109164","url":null,"abstract":"<div><div>The fine-grained functional organization of the human lateral prefrontal cortex (PFC) remains poorly understood. Previous fMRI studies delineated focal domain-general, or multiple-demand (MD), PFC areas that co-activate during diverse cognitively demanding tasks. While there is some evidence for category-selective (face and scene) patches, in human and non-human primate PFC, these have not been systematically assessed. Recent precision fMRI studies have also revealed sensory-biased PFC patches adjacent to MD regions. To investigate if this topographic arrangement extends to other domains, we analyzed two independent fMRI datasets (n = 449 and n = 37) utilizing the high-resolution multimodal MRI approaches of the Human Connectome Project (HCP). Both datasets included cognitive control tasks and stimuli spanning different categories: faces, places, tools and body parts. Contrasting each stimulus category against the remaining ones revealed focal interdigitated patches of activity located adjacent to core MD regions. The face and place results were robust, replicating across different executive tasks, experimental designs (block and event-related) and at the single subject level. In one dataset, where participants performed both category and sensory tasks, place patches overlapped with visually biased regions, while face patches were positioned between visual and auditory biases. Our results paint a refined view of the fine-grained functional organization of the PFC, revealing a recurring motif of interdigitated domain-specific and domain-general circuits. This organization offers new constraints for models of cognitive control, cortical specialization and development.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"214 ","pages":"Article 109164"},"PeriodicalIF":2.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143924244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Linking behavioral deficits with underlying neural property changes in amblyopia 弱视的行为缺陷与潜在神经特性改变的联系

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-05-03 DOI: 10.1016/j.neuropsychologia.2025.109156

Jinli Zhu , Yijin Han , Xiaolin Huang , Yufan Feng , Xiaowei Ruan , Wenman Lin , Jiawei Zhou , Fang Hou

{"title":"Linking behavioral deficits with underlying neural property changes in amblyopia","authors":"Jinli Zhu , Yijin Han , Xiaolin Huang , Yufan Feng , Xiaowei Ruan , Wenman Lin , Jiawei Zhou , Fang Hou","doi":"10.1016/j.neuropsychologia.2025.109156","DOIUrl":"10.1016/j.neuropsychologia.2025.109156","url":null,"abstract":"<div><div>While it is widely accepted that abnormal visual experience during critical period can lead to significant functional deficits and altered neural property, the quantitative link between behavioral visual losses and underlying neural changes remains elusive. To address this gap, we systematically varied stimulus orientation and contrast to measure 2D psychometric functions of amblyopic and normally sighted participants at two different spatial frequencies. A biologically-interpretable neural population model explicitly incorporated with neural contrast response function (CRF) and orientation tuning property accounted for the complex performance data for both groups. Our results revealed that the poor performance in the amblyopic group can be excellently explained by a rightward-shifted CRF at higher spatial frequency and reduced population Fisher information for coding orientation. Moreover, regression analysis revealed that the behavior contrast threshold from an independent measurement significantly depended on the neural properties estimated by the model. This study demonstrates the potential of biologically-interpretable models to quantitatively bridge the gap between behavioral deficits and underlying neural changes, offering a promising tool for understanding normal and abnormal visual systems.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"214 ","pages":"Article 109156"},"PeriodicalIF":2.0,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143916150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disrupted flexible use of context-dependent relational memory in adults following moderate-severe traumatic brain injury 成人中重度创伤性脑损伤后情境依赖关系记忆的灵活使用中断

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-04-30 DOI: 10.1016/j.neuropsychologia.2025.109157

Hillary Schwarb , Michael Dulas , Nirav Patel , Nathaniel A. Bouton , Neal J. Cohen , Melissa C. Duff

{"title":"Disrupted flexible use of context-dependent relational memory in adults following moderate-severe traumatic brain injury","authors":"Hillary Schwarb , Michael Dulas , Nirav Patel , Nathaniel A. Bouton , Neal J. Cohen , Melissa C. Duff","doi":"10.1016/j.neuropsychologia.2025.109157","DOIUrl":"10.1016/j.neuropsychologia.2025.109157","url":null,"abstract":"<div><div>Learning associative information and extracting regularities from that remembered information to adaptively meet goals is a hallmark of navigating life. Adaptive goal-directive behavior has been historically attributed to prefrontal functions, and more recently to hippocampal relational memory. Disruptions in either of these systems, both frequently seen in Traumatic Brain Injury (TBI), have far reaching consequences in everyday life. In the current study, we investigate the impact of chronic, moderate-to-severe TBI on both relational memory processes as well as the ability to use regularities or rules extracted from that remembered information to guide behavior via both overt responses and eye-tracking. Individuals with and without TBI completed a context-dependent relational memory task designed to assess both 1) the formation and organization of overlapping relational associations (hippocampal-dependent); and 2) the acquisition and flexible use of learned, context-dependent rules (ventromedial prefrontal-dependent). Behavioral measures revealed that relative to neurotypical matched comparison participants, participants with TBI were significantly impaired on context-dependent relational memory measures, but showed spared memory guided rule-use. Eye-tracking data indicated largely intact information gathering at study for participants with TBI, but impaired flexibility at test leading to poor behavioral outcomes. Critically, these data suggest that relational memory impairment is a significant source of behavioral dysfunction in TBI, which likely contributes to poor outcomes in both laboratory testing and real-life, long-term trajectories following injury. Furthermore, this study highlights the feasibility and strength of incorporating eye-tracking into studies of TBI to gain novel insights into information gathering and use across time.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"214 ","pages":"Article 109157"},"PeriodicalIF":2.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The use of F0 in speech segmentation by adults with dyslexia and skilled readers 有阅读障碍和熟练读者的成人使用F0进行语音分割

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-04-28 DOI: 10.1016/j.neuropsychologia.2025.109155

Mar Cordero-Rull , Ambre Denis-Noël , Elsa Spinelli , Fanny Meunier

引用次数: 0

Decoding of lexical items and grammatical features in EEG: A cross-linguistic study 脑电词汇项目解码与语法特征的跨语言研究

IF 2 3区心理学

Neuropsychologia Pub Date : 2025-04-23 DOI: 10.1016/j.neuropsychologia.2025.109150

Jeonghwa Cho , Jonathan R. Brennan

{"title":"Decoding of lexical items and grammatical features in EEG: A cross-linguistic study","authors":"Jeonghwa Cho , Jonathan R. Brennan","doi":"10.1016/j.neuropsychologia.2025.109150","DOIUrl":"10.1016/j.neuropsychologia.2025.109150","url":null,"abstract":"<div><div>Diverse evidence supports the theory that bilingual language users have language-invariant representations of concepts and grammatical forms such as argument structure. Here we extend that work to test the representation of morphosyntactic features and lexical concepts in typologically different languages. Specifically, we deploy machine learning techniques with EEG data collected from eighteen Korean-English bilinguals while they read singular and plural nouns and present and past tense verbs in English and Korean. Whereas event-related potentials (ERPs) analyses show limited sensitivity to discriminate lexical, number, and tense information, neural decoding revealed robust within-language classification of lexical and morphosyntactic information in both languages. In contrast, between-languages decoding was possible only for number information; decoding of lexical items and tense did not generalize between the two languages, even when accounting for temporal differences. These results indicate stable within-language EEG representations for lexical items and morphosyntactic features but suggest that only the number feature show evidence for shared EEG response patterns between the two languages studied.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"213 ","pages":"Article 109150"},"PeriodicalIF":2.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143887307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0