Neuropsychologia最新文献

{"title":"Transformation but not generation of motor images is disrupted following stimulation over the left inferior parietal lobe","authors":"Alisha D. Davis ,&nbsp;Matthew W. Scott ,&nbsp;AnnaMae K. Pond ,&nbsp;Austin J. Hurst ,&nbsp;Tareq Yousef ,&nbsp;Sarah N. Kraeutner","doi":"10.1016/j.neuropsychologia.2024.109013","DOIUrl":"10.1016/j.neuropsychologia.2024.109013","url":null,"abstract":"<div><div>Motor imagery (MI) involves the generation, maintenance, and transformation of motor images; yet, the neural underpinnings of each stage are not well understood. Here, we investigated the role of the left inferior parietal lobe (IPL) in the stages of MI. Healthy participants (N = 20) engaged in a MI task (making judgments about hands presented on a screen; hand laterality judgment task) over two days. Past literature demonstrates the mental rotation of hands in this task involves implicit MI (i.e., where MI occurs spontaneously in the absence of explicit instructions). During the task, active (Day A; 120% resting motor threshold) or sham (Day B; placebo) neuronavigated transcranial magnetic stimulation (TMS) was applied to the left IPL (location determined from past neuroimaging work) on 50% of trials at 250, 500, or 750ms post-stimulus onset, corresponding to different stages of MI. A/B days were randomized across participants. Linear mixed effects (LME) modelling conducted on reaction time and accuracy revealed that longer reaction times were observed when TMS was delivered at 750ms after trial onset, and more greatly for active vs. sham stimulation. This effect was exacerbated for palm-vs. back-view stimuli and for left vs. right hands. Accuracy overall was decreased for active vs. sham stimulation, and to a greater extent for palm-vs. back-view stimuli. Findings suggest that the left IPL is involved in image transformation. Overall this work informs on the neural underpinnings of the stages of MI.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142444655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What guides the judgment of learning: Memory or heuristics? An event-related potential study","authors":"Soner Yücetepe,&nbsp;Metehan Irak","doi":"10.1016/j.neuropsychologia.2024.109011","DOIUrl":"10.1016/j.neuropsychologia.2024.109011","url":null,"abstract":"<div><div>Memory monitoring ability is essential for the effectiveness of learning processes. Judgment of Learning (JOL), a metacognitive judgment, is commonly used to measure this ability. An ongoing debate questions whether JOL is an outcome of an inferential or recollective experience, as suggested by different hypotheses regarding the underlying cognitive mechanisms of this judgment. To address this question through a neuroscientific perspective, we aimed to investigate the temporal dynamic of JOL adopting event-related potential (ERP) methodology. Seventy-two young adults participated in an episodic memory task involving word-pairs as stimuli. Their JOLs were obtained through categorical choices in a delayed condition. Additionally, their memory performance was tested in the recognition phase. ERP components were compared for different JOL levels, as well as for the hit responses in the recognition test according to their JOL levels. The analyses showed that JOL processes are observable within an early time window after stimulus presentation, as evidenced by elicitation of the P100, N100, P200, N200, and P300 components across all JOL levels. However, only the amplitude of the N100 varied among these levels. A negative ERP component with 330–500 ms latency was also evident for all JOL levels in the central and parietal electrodes, which did not differ in amplitude. The analyses of the recognition phase ERPs showed that the hit responses did not exhibit a significant difference in the familiarity-related mid-frontal old/new effect (FN400) amplitude; however, those with high level of JOL elicited recollection-related parietal old-new effect with a smaller amplitude. These findings support both hypotheses suggesting that JOL is influenced by heuristics and the retrievability of information.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term retention of real-world experiences in a patient with profound amnesia","authors":"Adrian W. Gilmore ,&nbsp;Sam Audrain ,&nbsp;Joseph Snow ,&nbsp;Elyse Gollomp ,&nbsp;Jenna M. Wilson ,&nbsp;Anna M. Agron ,&nbsp;Dima A. Hammoud ,&nbsp;John A. Butman ,&nbsp;Alex Martin","doi":"10.1016/j.neuropsychologia.2024.109010","DOIUrl":"10.1016/j.neuropsychologia.2024.109010","url":null,"abstract":"<div><div>The medial temporal lobe (MTL) is known to be critical for healthy memory function, but patients with MTL damage can, under certain circumstances, demonstrate successful learning of novel information encountered outside the laboratory. Here, we describe a patient, D.C., with extensive but focal bilateral MTL damage centering primarily on his hippocampus, whose memory for real-world experiences was assessed. Tests of remote memory indicated at least some capacity to retrieve specific details. To test his anterograde memory, he was taken on a tour of the NIH Clinical Center, with unique events occurring at each of ten specific locations. His memory for these events was tested after 1 h, and again after fifteen months. Initially, D.C. could not recall having participated in the tour, even when cued with photographs of specific places he had visited. However, he achieved 90% accuracy on a forced choice recognition test of old and new objects he encountered on the tour, and his recognition of these objects remained intact over a year later when he was tested once again. Subsequent recognition memory tests using novel picture stimuli in a standard laboratory-style computer task resulted in chance-level performance across multiple test formats and stimulus categories. These findings suggest a potentially privileged role for natural learning for long-term retention in a patient with severely damaged medial temporal lobes.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Different plasticity patterns of schematic and dynamic expectations in musical pitch prediction","authors":"Kai Ishida ,&nbsp;Hiroshi Nittono","doi":"10.1016/j.neuropsychologia.2024.109012","DOIUrl":"10.1016/j.neuropsychologia.2024.109012","url":null,"abstract":"","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibitory control and working memory predict rhythm production abilities in patients with neurocognitive deficits","authors":"Alina S. Löser ,&nbsp;Simone Dalla Bella ,&nbsp;Peter E. Keller ,&nbsp;Arno Villringer ,&nbsp;Hellmuth Obrig ,&nbsp;Annerose Engel","doi":"10.1016/j.neuropsychologia.2024.109009","DOIUrl":"10.1016/j.neuropsychologia.2024.109009","url":null,"abstract":"<div><div>Deficits in rhythm perception and production have been reported in a variety of psychiatric, neurodevelopmental and neurologic disorders. Since correlations between rhythmic abilities and cognitive functions have been demonstrated in neurotypical individuals, we here investigate whether and how rhythmic abilities are associated with cognitive functions in 35 participants with neurocognitive deficits due to acquired brain lesions. We systematically assessed a diverse set of rhythm perception and production abilities including time and beat perception and finger-tapping tasks. Neuropsychological tests were applied to assess separable cognitive functions. Using multiple regression analyses we show that lower variability in aligning movements to a pacing sequence was predicted by better inhibitory control and better working memory performance. Working memory performance also predicted lower variability of rhythmic movements in the absence of an external pacing sequence and better anticipatory timing to sequences with gradual tempo changes. Importantly, these predictors remained significant for all regression models when controlling for other cognitive variables (i.e., cognitive flexibility, information processing speed, and verbal learning ability) and potential confounders (i.e., age, symptom strength of depression, manual dexterity, duration of illness, severity of cognitive impairment, and musical experience). Thus, all rhythm production abilities were significantly predicted by measures of executive functions. In contrast, rhythm perception abilities (time perception/beat perception) were not predicted by executive functions in this study. Our results, enhancing the understanding of cognitive underpinnings of rhythmic abilities in individuals with neurocognitive deficits, may be a first mandatory step to further potential therapeutic implications of rhythm-based interventions in neuropsychological rehabilitation.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to 'The human brain deals with violating general color or depth knowledge in different time courses' [201 (2024) 1-9/ NSY_108941].","authors":"Xiaoyu Tang, Shilong Yu, Shigeko Takahashi, Jiajia Yang, Yoshimichi Ejima, Yulin Gao, Qiong Wu, Jinglong Wu","doi":"10.1016/j.neuropsychologia.2024.109001","DOIUrl":"10.1016/j.neuropsychologia.2024.109001","url":null,"abstract":"","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142375756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increasing mind wandering with accelerated intermittent theta burst stimulation over the left dorsolateral prefrontal cortex","authors":"Steffen Rygg Aasen,&nbsp;Ragnhild Nicolaisen Drevland,&nbsp;Gábor Csifcsák,&nbsp;Matthias Mittner","doi":"10.1016/j.neuropsychologia.2024.109008","DOIUrl":"10.1016/j.neuropsychologia.2024.109008","url":null,"abstract":"<div><div>Mind wandering (MW) is the intentional or unintentional experience of attending to internal task-unrelated thoughts while being occupied with an external task. Even though maintaining task focus is assumed to require executive functions (EF), it is not clear how and to what extent MW and EF interact. Research has found that activity in the dorsolateral prefrontal cortex (DLPFC) is associated with EF and MW. To understand the causal role of the DLPFC in relation to MW and EF, researchers have turned to non-invasive brain stimulation. Thus far, most studies have used transcranial direct current stimulation, but the results have been inconclusive. To further elucidate the relationship between the DLPFC, EF and MW, we conducted a pre-registered, sham-controlled, triple-blinded within-subject experiment by combining intermittent theta burst stimulation (iTBS) interleaved with a recently developed MW-EF task. In contrast to our expectations, participants reported significantly more MW following real iTBS as compared to sham stimulation. However, at the same time, psychomotor precision and EF improved, indicating that participants were able to engage in resource-intensive MW while simultaneously performing well on the task. We argue that iTBS enhanced the underlying executive resources that could be used to increase both MW and task performance in line with the resource-control view of MW. This finding opens exciting avenues for studying the complex interplay between MW and EF and provides empirical support for the utility of iTBS in improving executive performance during a demanding cognitive task.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multivariate and network lesion mapping reveals distinct architectures of domain-specific post-stroke cognitive impairments","authors":"Margaret Jane Moore ,&nbsp;Jason B. Mattingley ,&nbsp;Nele Demeyere","doi":"10.1016/j.neuropsychologia.2024.109007","DOIUrl":"10.1016/j.neuropsychologia.2024.109007","url":null,"abstract":"<div><h3>Background</h3><div>The purpose of this study was to identify patterns of structural disconnection and multivariate lesion-behaviour relationships associated with post-stroke deficits across six commonly impacted cognitive domains: executive function, language, memory, numerical processing, praxis, and visuospatial attention.</div></div><div><h3>Methods</h3><div>Stroke survivors (n = 593) completed a brief domain-specific cognitive assessment (the Oxford Cognitive Screen (OCS)) during acute hospitalisation. Network-level and multivariate (sparce canonical correlation) lesion mapping analyses were conducted to identify focal neural correlates and distributed patterns of structural disconnection associated with impairment on each of the 16 OCS measures.</div></div><div><h3>Results</h3><div>Network-level and multivariate lesion mapping analyses identified significant correlates for 12/16 and 10/16 OCS measures, respectively which were largely consistent with correlates reported in past work. Language impairments were reliably localised to network- and voxel-level correlates centred in left fronto-temporal regions. Memory impairments were associated with disconnection in a large network of left hemisphere regions. Number processing deficits were associated with damage to voxels centred in the left insular/opercular cortex, as well as disconnection within the surrounding white matter tracts. Within the domain of attention, different subtypes of visuospatial neglect were linked to distinct but partially overlapping patterns of disconnection and voxel-level damage. Praxis impairment was not linked to any voxel-level regions but was significantly associated with disconnection within the left hemisphere dorsal attention network.</div></div><div><h3>Conclusion</h3><div>These results highlight the utility of routine, domain-specific cognitive assessment and imaging data for theoretically-driven lesion mapping analyses, while providing novel insight into the complex anatomical correlates of common and debilitating post-stroke cognitive impairments.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142372427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroanatomical correlates and predictors of psychotic symptoms in Alzheimer's disease: A systematic review and meta-analysis","authors":"Sara Scarfo ,&nbsp;Antonella M.A. Marsella ,&nbsp;Loulouda Grigoriadou ,&nbsp;Yashar Moshfeghi ,&nbsp;William J. McGeown","doi":"10.1016/j.neuropsychologia.2024.109006","DOIUrl":"10.1016/j.neuropsychologia.2024.109006","url":null,"abstract":"<div><h3>Background</h3><div>Psychotic symptoms (hallucinations and delusions) are a type of neuropsychiatric symptom found during Alzheimer's Disease (AD).</div></div><div><h3>Objective</h3><div>This systematic review aims to comprehensively capture, analyse, and evaluate the body of evidence that has investigated associations between brain regions/networks and psychotic symptoms in AD.</div></div><div><h3>Methods</h3><div>The protocol, created according to the PRISMA guidelines, was pre-registered on OSF (<span><span>https://osf.io/tg8xp/</span><svg><path></path></svg></span>). Searches were performed using PubMed, Web of Science and PsycInfo. A partial coordinate-based meta-analysis (CBMA) was performed based on data availability.</div></div><div><h3>Results</h3><div>Eighty-two papers were selected: delusions were found to be associated mainly with right fronto-temporal brain regions and the insula; hallucinations mainly with fronto-occipital areas; both were frequently associated with the anterior cingulate cortex. The CBMA, performed on the findings of fourteen papers on delusions, identified a cluster in the frontal lobe, one in the putamen, and a smaller one in the insula.</div></div><div><h3>Conclusions</h3><div>The available evidence highlights that key brain regions, predominantly in the right frontal lobe, the anterior cingulate cortex, and temporo-occipital areas, appear to underpin the different manifestations of psychotic symptoms in AD and MCI. The fronto-temporal areas identified in relation to delusions may underpin a failure to assimilate correct information and consider alternative possibilities (which might generate and maintain the delusional belief), and dysfunction within the salience network (anterior cingulate cortex and insula) may suggest a contribution for how internal and external stimuli are identified; the fronto-occipital areas linked to hallucinations may indicate diminished sensory processing and non-optimal predictive processing, that together contribute to misinterpretation of stimuli and misperceptions; the fronto-temporal and occipital areas, as well as the anterior cingulate cortex were linked to the psychotic cluster.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142350908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On the lasting impact of mild traumatic brain injury on working memory: Behavioural and electrophysiological evidence","authors":"Amaya J. Fox ,&nbsp;Natasha Matthews ,&nbsp;Zeguo Qiu ,&nbsp;Hannah L. Filmer ,&nbsp;Paul E. Dux","doi":"10.1016/j.neuropsychologia.2024.109005","DOIUrl":"10.1016/j.neuropsychologia.2024.109005","url":null,"abstract":"<div><div>Despite increasing recognition of the significance of mild traumatic brain injury (mTBI), the long-term cognitive consequences of the injury remain unclear. More sensitive measures that can detect subtle cognitive changes and consideration of individual variability are needed to properly characterise cognitive outcomes following mTBI. Here, we used complex behavioural tasks, individual differences approaches, and electrophysiology to investigate the long-term cognitive effects of a history of mTBI. In Experiment 1, participants with self-reported mTBI history (<em>n=</em>82) showed poorer verbal working memory performance on the operation span task compared to control participants (<em>n</em>=88), but there were no group differences in visual working memory, multitasking, cognitive flexibility, attentional control, visuospatial ability, or information processing speed. Individual differences analyses revealed that time since injury and presence of memory loss predicted visual working memory capacity and visuospatial ability, respectively, in those with mTBI history. In Experiment 2, participants with mTBI history (<em>n</em>=20) again demonstrated poorer verbal working memory on the operation span task compared to control participants (<em>n</em>=38), but no group differences were revealed on a visuospatial complex span task or simpler visual working memory measures. We also explored the electrophysiological indices of visual working memory using EEG during a change detection task. No differences were observed in early sensory event-related potentials (P1, N1) or the later negative slow wave associated with visual working memory capacity. Together, these findings suggest that mTBI history may be associated with a lasting, isolated disruption in the subsystem underlying verbal working memory storage. The results emphasise the importance of sensitive cognitive measures and accounting for individual variability in injury characteristics when assessing mTBI outcomes.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}