Neuropsychologia最新文献

{"title":"Early audiovisual integration in target processing under continuous noise: Behavioral and EEG evidence","authors":"Junjie Wang ,&nbsp;Mingkun Guo ,&nbsp;Jie Zhang ,&nbsp;Yanru Bai ,&nbsp;Guangjian Ni","doi":"10.1016/j.neuropsychologia.2025.109128","DOIUrl":"10.1016/j.neuropsychologia.2025.109128","url":null,"abstract":"<div><div>Multisensory integration is interconnected across various information reception. The stage and mechanism of brain response to audiovisual integration have not been fully understood. In this study, we designed audiovisual and unisensory experiments to investigate task performance and electrophysiological characteristics associated with audiovisual integration in a continuous background interference environment using materials collected from the underwater environment. Behavioral results showed that the reaction time (RT) was shorter, and the accuracy was higher in the audiovisual experiment. The cumulative distribution function (CDF) results of RT indicated that audiovisual integration supported the co-activation model. Event-related potential (ERP) results revealed shorter latency of the P1 and N1 components in the audiovisual experiment. Microstate analysis indicated that the parietal-occipital area may play a key role in audiovisual integration. Moreover, event-related spectral perturbation (ERSP) results demonstrated the critical role of low-frequency oscillation in audiovisual integration at the early stage. Our findings support the view that the beneficial effect of audiovisual integration is predominantly upon the early stage of neural information processing, including task-independent information.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"211 ","pages":"Article 109128"},"PeriodicalIF":2.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total recall: Detecting autobiographical memory retrieval in the absence of behaviour","authors":"Matthew Kolisnyk ,&nbsp;Geoffrey Laforge ,&nbsp;Marie-Ève Gagnon ,&nbsp;Jonathan Erez ,&nbsp;Adrian M. Owen","doi":"10.1016/j.neuropsychologia.2025.109129","DOIUrl":"10.1016/j.neuropsychologia.2025.109129","url":null,"abstract":"<div><div>Functional neuroimaging has fundamentally changed our understanding of disorders of consciousness (DoC). While many DoC patients exhibit minimal to no <em>behavioural</em> responsiveness, a significant minority show <em>neural</em> evidence of awareness and preserved cognitive functioning. Although several cognitive functions have been explored in DoC patients, autobiographical memory -- the ability to form and retrieve personal memories -- has yet to be investigated. To address this gap, we used functional magnetic resonance imaging (fMRI) to investigate autobiographical memory in one DoC patient. The patient viewed video clips across three conditions: (1) <em>Own -</em> clips recorded from their perspective during a recent mall visit; (2) <em>Other</em> - clips from a healthy control’s visit to the same mall; and (3) <em>Bookstore</em> - novel clips from an entirely different store that had not been visited. We trained a linear support vector classifier to associate fMRI activity in canonical autobiographical memory regions with each condition using data from twelve healthy participants. We then applied the trained model to the patient’s data to ’decode’ which condition their fMRI activity predicted. The model accurately distinguished between <em>Own</em>, <em>Other</em>, and <em>Bookstore</em> conditions in the patient (<em>Balanced Accuracy</em> = 0.448, <em>p</em> = .032), with performance within the control group range (<em>p</em> = .068). Similarly, the model distinguished between the <em>Own</em> and <em>Other</em> conditions above chance (<em>Balanced Accuracy</em> = 0.609, <em>p</em> = .032) and within the control group’s distribution (<em>p</em> = .620), suggesting that the patient was still able to differentiate personal experiences from visually similar scenes, despite being behaviourally unable to report that this was the case. These findings provide preliminary evidence that autobiographical memory processes, critical to conscious awareness and identity, remain intact in some DoC patients, shedding further light on their covert capabilities and inner experiences.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"211 ","pages":"Article 109129"},"PeriodicalIF":2.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the semantic organization of animal fluency in mild Alzheimer's disease through time-course analysis and LDA topic modelling","authors":"Y. Itaguchi ,&nbsp;K. Waterloo ,&nbsp;S.H. Johnsen ,&nbsp;C. Rodríguez-Aranda","doi":"10.1016/j.neuropsychologia.2025.109126","DOIUrl":"10.1016/j.neuropsychologia.2025.109126","url":null,"abstract":"<div><div>Deterioration of semantic memory represents an important feature of Alzheimer's disease (AD), which has been widely addressed in neuropsychological research. A way to understand semantic integrity in AD patients is through a detailed analysis of verbal fluency (VF) performance. In the present study, we used an innovative methodology that combines measures of between-words latencies together with automatized identification of semantic clusters via Latent Dirichlet Analysis (LDA) to acquire a more precise understanding of the dynamics and semantic organization of VF in patients at early stages of AD. Importantly, and diverging from customary procedures, we included VF errors (i.e., repetitions and intrusions) across analyses. For comparison, a group of healthy older adults and young individuals were also examined. Standard parameters including total correct answers, number of clusters, mean cluster size (MCS), cluster duration, and within and out-of-cluster intervals were calculated. These parameters were expressed as mean values in 1-min VF trials and by calculating mean values in four 15-s time windows. Results for the 1-min trial demonstrated significantly larger mean cluster sizes (MCS) and fewer generated answers in AD patients compared to the healthy groups. No additional group differences were found neither on time intervals (both within and out-of-clusters), nor on the 15-s time windows analyses. These data suggest that the clustering ability of mild AD patients might be affected by executive impairments promoting larger MCS. At the same time, we found similar semantic processes and timings in patients and healthy participants. The main difference resides in the structure of the patients' clusters, which encompassed erroneous answers. We advance the idea that production of errors might not only be a consequence of executive dysfunction or working memory deterioration, but also a sign that associative semantic mechanisms are still active early in the disease, despite an evident loss of information.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"211 ","pages":"Article 109126"},"PeriodicalIF":2.0,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Self-Awareness after Severe Acquired Brain Injury: Systematic Review and Recommendations for a new Classification of Offline Self-Awareness.","authors":"Umberto Bivona, Dolores Villalobos","doi":"10.1016/j.neuropsychologia.2025.109123","DOIUrl":"https://doi.org/10.1016/j.neuropsychologia.2025.109123","url":null,"abstract":"<p><p>Impairment in self-awareness (SA) is an important obstacle in neurorehabilitation of severe acquired brain injury (ABI) patients since it can cause failure in adopting adequate compensatory strategies, or the implementation of ineffective or dangerous behaviors. Accordingly, it should be assessed as early and accurately as possible, even if, to date, no consensus exists on how best to measure SA, and on its explanatory models. The present systematic review aimed to address: (a) to which extent ISA has been assessed in studies enrolling severe ABI patients; (b) whether studies on assessment of SA after severe ABI considered any explanatory models of SA and which measures have been utilized accordingly; (c) possible gaps or criticism in the extant research on severe ABI patients; and (d) to provide a novel proposal for SA assessment/classification based on the results and discussion from the systematic review conducted in this well selected population of patients. A systematic review was carried out in the databases PubMed, Web of Science and PsycINFO; 701 studies were retrieved and finally 54 met the inclusion criteria. Our review evidenced the paucity of studies on assessment of SA in patients with severe ABI that specified the model and the level of SA. Only a few measures of SA went beyond its intellectual and declarative aspects, thus hindering an exhaustive assessment and a full comprehension of SA. Accordingly, we propose a more comprehensive classification of offline anticipatory SA, with some important implications in the neurorehabilitation field. The review demonstrated the need of measuring SA beyond its declarative level, differentiating between declarative and real anticipatory SA, as well as of assessing SA at both offline and online levels.</p>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":" ","pages":"109123"},"PeriodicalIF":2.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioral and neuroanatomical effects of soccer heading training in virtual reality: A longitudinal fMRI case study","authors":"Fabio Richlan","doi":"10.1016/j.neuropsychologia.2025.109124","DOIUrl":"10.1016/j.neuropsychologia.2025.109124","url":null,"abstract":"<div><div>Virtual reality (VR) technology has received considerable attention over the last few years, with applications in many performance domains including training of sports-related mental and motor skills. The exact psychological and neurobiological mechanisms underlying potential VR training effects in athletes, however, remain largely unknown.</div><div>The present longitudinal functional magnetic resonance imaging (fMRI) case study reports behavioral and neuroanatomical effects of VR soccer (a.k.a. football) heading training in a male adult amateur player. The study was conducted over 8 weeks, starting with a pre-test, followed by a 4-week VR training phase, during which weekly fMRI assessments and the first behavioral post-test were conducted. After an additional 4-week retention phase, the final fMRI assessment and the second behavioral post-test were conducted.</div><div>Substantial improvement in real-life heading performance was accompanied by both structural and functional neuroanatomical changes. The comparison of the T1-weighted images revealed an increase in GM volume in the left thalamus and an increase in WM volume in the bilateral cerebellum. Furthermore, the analysis of the surface images showed an increase in cortical thickness in the right insula, left inferior temporal gyrus, left parahippocampal gyrus, left lingual gyrus, left posterior cingulate cortex, and bilateral anterior cingulate and medial prefrontal cortex. The seed-based correlation analyses of the resting-state fMRI data revealed manifold increases in functional connectivity within and between important brain networks.</div><div>This study contributes to the growing literature on VR training in athletes and provides the world's first evidence on fundamental neurobiological mechanisms underlying neuroplasticity related to VR training effects in sports.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"211 ","pages":"Article 109124"},"PeriodicalIF":2.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring implicit line orientation discrimination using fast periodic visual stimulation","authors":"Oliver Hermann ,&nbsp;Carla Leonardi ,&nbsp;Karin Petrini ,&nbsp;Elizabeth Coulthard ,&nbsp;George Stothart","doi":"10.1016/j.neuropsychologia.2025.109122","DOIUrl":"10.1016/j.neuropsychologia.2025.109122","url":null,"abstract":"<div><div>The fast periodic visual stimulation oddball paradigm (FPVS-oddball) is an electroencephalography (EEG) marker of discrimination between two classes of frequency tagged stimuli (standards and oddballs). Here, we probe low-level visual function using FPVS-oddball, with a view to its future use as a sensitive diagnostic marker of visuoperceptual cognitive impairment. Thirty participants (21 (±5) years, 7 males) completed five FPVS-oddball conditions that implicitly measured their ability to discriminate an oddball line orientation (1°,5°,10°,30°,80°), from a standard vertical line, as well as an equiprobable control condition. Twenty-four participants (24 (±5) years, 5 males) completed a retest session around one month later. Following 100s of recording, activity at the oddball presentation frequency, a neural signal of discrimination between standard and oddball stimuli, was observed in response to lines of 5° and above. The magnitude of this oddball response increased as oddball lines deviated more from vertical. Demonstrating consistency in individual participants, oddball responses were present in 30/30 participants in response to a deviation of 30° and 29/30 in response to a deviation of 80°. At larger deviations, oddball responses were highly reliable between sessions, measured using intraclass correlations. Overall, this study showed that FPVS-oddball can consistently and reliably measure line orientation discrimination in individual participants. The consistency and reliability of oddball responses in the cognitively healthy, could provide a strong baseline that clinical group's performance could be compared to, guiding neurocognitive assessment.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"211 ","pages":"Article 109122"},"PeriodicalIF":2.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motor markers of congenital cerebellar hypoplasia","authors":"Elisa Straulino ,&nbsp;Maria Devita ,&nbsp;Luisa Sartori ,&nbsp;Adele Ravelli ,&nbsp;Marina De Rui ,&nbsp;Matteo Bendini ,&nbsp;Lorenzo Pini ,&nbsp;Andrea Spoto ,&nbsp;Sonia Betti ,&nbsp;Erika Marinuzzi ,&nbsp;Daniela Mapelli ,&nbsp;Umberto Castiello ,&nbsp;Chiara Begliomini","doi":"10.1016/j.neuropsychologia.2025.109121","DOIUrl":"10.1016/j.neuropsychologia.2025.109121","url":null,"abstract":"<div><div>The Reach-to-Grasp (RtG) movement is a fundamental feature of human competence and a widely adopted model for the study of functional movements in both healthy and disease-affected individuals. In particular, 3-D kinematic analysis of RtG allows the study of fine hand movements and submovements, described as secondary fluctuations of the main movement. The aim of this study was to use a RtG movement to test upper limb motor performance in a patient with ataxic syndrome due to cerebellar hypoplasia. 3-D kinematical recording and MRI-based structural measures were combined to provide a comprehensive characterization of the movement and its neural underpinnings at the baseline and after a 2 years follow-up. In terms of kinematics, a dissociation between reaching and grasping performance was observed over time: while grasping appeared to be characterized by an improvement at the 2 years follow-up, reaching showed a significant increase of jerk submovements, suggesting a loss of functionality in feedback mechanisms allowing for smoothness of the movement. At the neural level, an increase of gray matter volume of the anterior right cerebellar hemisphere, alongside with an increased structural connectivity within the sensorimotor network were observed at the 2 years follow up, presumably mirroring the improvement observed for the grasping component.</div><div>These results highlight the potential of the jerk submovements as a motor biomarker in contexts where feedback mechanisms may be compromised, such as in the case of cerebellar dysfunctions, contributing to the development of new methods for the motor assessment of patients in clinical settings.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"211 ","pages":"Article 109121"},"PeriodicalIF":2.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reward prediction-error promotes the neural encoding of episodic learning","authors":"Fangfang Liu ,&nbsp;Yingjie Jiang ,&nbsp;Bin Du","doi":"10.1016/j.neuropsychologia.2025.109120","DOIUrl":"10.1016/j.neuropsychologia.2025.109120","url":null,"abstract":"<div><div>Reward prediction-error carries significant implications for learning, facilitating the process by influencing prior knowledge and shaping future expectations and decisions. However, the electrophysiological mechanism through which reward prediction-error impacts learning remains incompletely understood. This study aimed to investigate the neural characteristics of reward prediction-error and its effect on recognition memory using Event-Related Potentials (ERPs). Behavioral results indicate that unsigned reward prediction-error indeed enhances recognition performance, with reaction times being slower in “remember” responses compared to correct predictions. The ERP findings conform to a three-stage model of reward prediction-error, suggesting that physical salience is swiftly detected (N1), followed by the processing of positive reward prediction-error (Feedback-Related Negativity, FRN), and ultimately, unsigned reward prediction-error or outcome evaluation (P300). Moreover, early physical salience signals were associated with subsequent “know” responses, while later unsigned reward prediction-error signals predicted subsequent recognition performance. This study not only revealed the neural processing mechanisms of reward prediction-error but also explored its impact on recognition performance, particularly familiarity or recollection processing.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"211 ","pages":"Article 109120"},"PeriodicalIF":2.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Memories or decisions? Bridging accounts of frontopolar function","authors":"Erica A. Boschin,&nbsp;Matthew Ainsworth,&nbsp;Juan M. Galeazzi,&nbsp;Mark J. Buckley","doi":"10.1016/j.neuropsychologia.2025.109119","DOIUrl":"10.1016/j.neuropsychologia.2025.109119","url":null,"abstract":"<div><div>Frontopolar cortex (FPC), for a long time elusive to functional description, is now associated with a wide range of cognitive processes. Prominent accounts of FPC function emerged from studies of memory (e.g., episodic and prospective memory; EM and PM, respectively) and of executive function (e.g., planning, multi-tasking, relational reasoning, cognitive branching, etc). In recent years, FPC function has begun to be described within the context of value-based decision making in terms of monitoring the value of alternatives and optimizing cognitive resources to balance the explore/exploit dilemma in the face of volatile environments. In this perspective, we propose that the broad counterfactual inference and behavioural flexibility account can help re-interpret findings from EM and PM studies and offer an explanatory bridge between the memory and executive function accounts. More specifically, we propose that counterfactual value monitoring in FPC modulates the reallocation of cognitive resources between present and past information and contributes to efficient episodic and prospective retrieval by concurrently assessing the value of competing memories in relation to the decision at hand and proactively evaluating future potential scenarios to anticipate optimal engagement of intentions.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"211 ","pages":"Article 109119"},"PeriodicalIF":2.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of representations is key to the enactment benefit: Insights from individuals with stroke lesions","authors":"Yadurshana Sivashankar ,&nbsp;Brady R. Roberts ,&nbsp;Myra A. Fernandes","doi":"10.1016/j.neuropsychologia.2025.109118","DOIUrl":"10.1016/j.neuropsychologia.2025.109118","url":null,"abstract":"<div><div>Previous research has suggested that performing an action during encoding, related to the meaning of a target word (known as ‘enactment’), benefits later memory retrieval relative to when the word is simply read. It has been suggested that enactment confers this memory benefit by promoting the formation of a multimodal memory trace through the integration of verbal and motoric representations, facilitated by the parietal lobe. More recent work has proposed that cognitive planning preceding the execution of enactment, via engagement of frontal lobe-based processes, is most critical for the memory benefit. Here, evidence for these two accounts was assessed by comparing memory in healthy controls relative to individuals with lesions to parietal or frontal brain areas. Frontal stroke participants and controls both showed significant enactment effects: Recall was better for words enacted at encoding relative to those that were silently read. In contrast, participants with parietal lesions did not show the effect. Results suggest that the integration of multimodal representations by parietal lobe-based processes is a critical step necessary to evoke the benefit of enactment on memory performance.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"211 ","pages":"Article 109118"},"PeriodicalIF":2.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}