Nature Human Behaviour最新文献

Human motor cortex encodes complex handwriting through a sequence of stable neural states 人类运动皮层通过一系列稳定的神经状态编码复杂的笔迹

IF 29.9 1区心理学

Nature Human Behaviour Pub Date : 2025-04-02 DOI: 10.1038/s41562-025-02157-x

Yu Qi, Xinyun Zhu, Xinzhu Xiong, Xiaomeng Yang, Nai Ding, Hemmings Wu, Kedi Xu, Junming Zhu, Jianmin Zhang, Yueming Wang

引用次数: 0

A neural geometry approach comprehensively explains apparently conflicting models of visual perceptual learning

IF 29.9 1区心理学

Nature Human Behaviour Pub Date : 2025-03-31 DOI: 10.1038/s41562-025-02149-x

Yu-Ang Cheng, Mehdi Sanayei, Xing Chen, Ke Jia, Sheng Li, Fang Fang, Takeo Watanabe, Alexander Thiele, Ru-Yuan Zhang

{"title":"A neural geometry approach comprehensively explains apparently conflicting models of visual perceptual learning","authors":"Yu-Ang Cheng, Mehdi Sanayei, Xing Chen, Ke Jia, Sheng Li, Fang Fang, Takeo Watanabe, Alexander Thiele, Ru-Yuan Zhang","doi":"10.1038/s41562-025-02149-x","DOIUrl":"https://doi.org/10.1038/s41562-025-02149-x","url":null,"abstract":"Visual perceptual learning (VPL), defined as long-term improvement in a visual task, is considered a crucial tool for elucidating underlying visual and brain plasticity. Previous studies have proposed several neural models of VPL, including changes in neural tuning or in noise correlations. Here, to adjudicate different models, we propose that all neural changes at single units can be conceptualized as geometric transformations of population response manifolds in a high-dimensional neural space. Following this neural geometry approach, we identified neural manifold shrinkage due to reduced trial-by-trial population response variability, rather than tuning or correlation changes, as the primary mechanism of VPL. Furthermore, manifold shrinkage successfully explains VPL effects across artificial neural responses in deep neural networks, multivariate blood-oxygenation-level-dependent signals in humans and multiunit activities in monkeys. These converging results suggest that our neural geometry approach comprehensively explains a wide range of empirical results and reconciles previously conflicting models of VPL.","PeriodicalId":19074,"journal":{"name":"Nature Human Behaviour","volume":"38 1","pages":""},"PeriodicalIF":29.9,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Women shaping behavioural science

IF 29.9 1区心理学

Nature Human Behaviour Pub Date : 2025-03-31 DOI: 10.1038/s41562-025-02161-1

Qing Cai, Mar Hicks, Emilia Huerta-Sanchez, Samara Klar, Misaki N. Natsuaki, Tanja van der Lippe

引用次数: 0

How growing up without siblings affects the adult brain and behaviour in the CHIMGEN cohort

IF 29.9 1区心理学

Nature Human Behaviour Pub Date : 2025-03-31 DOI: 10.1038/s41562-025-02142-4

Jie Tang, Jing Zhang, Wei Li, Meiyun Wang, Jingliang Cheng, Bing Zhang, Wenzhen Zhu, Shijun Qiu, Guangbin Cui, Yongqiang Yu, Weihua Liao, Hui Zhang, Bo Gao, Xiaojun Xu, Yunjun Yang, Tong Han, Zhenwei Yao, Quan Zhang, Wen Qin, Feng Liu, Meng Liang, Sijia Wang, Qiang Xu, Jiayuan Xu, Jilian Fu, Yuan Ji, Nana Liu, Peng Zhang, Dapeng Shi, Caihong Wang, Su Lui, Zhihan Yan, Feng Chen, Wen Shen, Yanwei Miao, Dawei Wang, Junfang Xian, Xiaochu Zhang, Kai Xu, Xi-Nian Zuo, Longjiang Zhang, Zhaoxiang Ye, Zuojun Geng, Jia-Hong Gao, Chunshui Yu

{"title":"How growing up without siblings affects the adult brain and behaviour in the CHIMGEN cohort","authors":"Jie Tang, Jing Zhang, Wei Li, Meiyun Wang, Jingliang Cheng, Bing Zhang, Wenzhen Zhu, Shijun Qiu, Guangbin Cui, Yongqiang Yu, Weihua Liao, Hui Zhang, Bo Gao, Xiaojun Xu, Yunjun Yang, Tong Han, Zhenwei Yao, Quan Zhang, Wen Qin, Feng Liu, Meng Liang, Sijia Wang, Qiang Xu, Jiayuan Xu, Jilian Fu, Yuan Ji, Nana Liu, Peng Zhang, Dapeng Shi, Caihong Wang, Su Lui, Zhihan Yan, Feng Chen, Wen Shen, Yanwei Miao, Dawei Wang, Junfang Xian, Xiaochu Zhang, Kai Xu, Xi-Nian Zuo, Longjiang Zhang, Zhaoxiang Ye, Zuojun Geng, Jia-Hong Gao, Chunshui Yu","doi":"10.1038/s41562-025-02142-4","DOIUrl":"https://doi.org/10.1038/s41562-025-02142-4","url":null,"abstract":"With the worldwide increase in only-child families, it is crucial to understand the effects of growing up without siblings (GWS) on the adult brain, behaviour and the underlying pathways. Using the CHIMGEN cohort, we investigated the associations of GWS with adult brain structure, function, connectivity, cognition, personality and mental health, as well as the pathway from GWS to GWS-related growth environments to brain and to behaviour development, in 2,397 pairs of individuals with and without siblings well matched in covariates. We found associations linking GWS to higher language fibre integrity, lower motor fibre integrity, larger cerebellar volume, smaller cerebral volume and lower frontotemporal spontaneous brain activity. Contrary to the stereotypical impression of associations between GWS and problem behaviours, we found positive correlations of GWS with neurocognition and mental health. Despite direct effects, GWS affects most brain and behavioural outcomes through modifiable environments, such as socioeconomic status, maternal care and family support, suggesting targets for interventions to enhance children’s healthy growth.","PeriodicalId":19074,"journal":{"name":"Nature Human Behaviour","volume":"36 1","pages":""},"PeriodicalIF":29.9,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The next generation of experimental research with LLMs

IF 29.9 1区心理学

Nature Human Behaviour Pub Date : 2025-03-31 DOI: 10.1038/s41562-025-02137-1

Gary Charness, Brian Jabarian, John A. List

引用次数: 0

Alcohol use disorder and body mass index show genetic pleiotropy and shared neural associations

IF 29.9 1区心理学

Nature Human Behaviour Pub Date : 2025-03-31 DOI: 10.1038/s41562-025-02148-y

Samantha G. Malone, Christal N. Davis, Zachary Piserchia, Michael R. Setzer, Sylvanus Toikumo, Hang Zhou, Emma L. Winterlind, Joel Gelernter, Amy Justice, Lorenzo Leggio, Christopher T. Rentsch, Henry R. Kranzler, Joshua C. Gray

{"title":"Alcohol use disorder and body mass index show genetic pleiotropy and shared neural associations","authors":"Samantha G. Malone, Christal N. Davis, Zachary Piserchia, Michael R. Setzer, Sylvanus Toikumo, Hang Zhou, Emma L. Winterlind, Joel Gelernter, Amy Justice, Lorenzo Leggio, Christopher T. Rentsch, Henry R. Kranzler, Joshua C. Gray","doi":"10.1038/s41562-025-02148-y","DOIUrl":"https://doi.org/10.1038/s41562-025-02148-y","url":null,"abstract":"Despite neurobiological overlap, alcohol use disorder (AUD) and body mass index (BMI) show minimal genetic correlation (rg), possibly due to mixed directions of shared variants. Here we applied MiXeR to investigate shared genetic architecture between AUD and BMI, conjunctional false discovery rate to detect shared loci and their directional effect, local analysis of (co)variant association for local rg, functional mapping and annotation to identify lead single-nucleotide polymorphisms, Genotype-Tissue Expression (GTEx) to examine tissue enrichment and BrainXcan to assess associations with brain phenotypes. MiXeR indicated 82.2% polygenic overlap, despite an rg of −0.03. The conjuctional false discovery rate method identified 132 shared lead single-nucleotide polymorphisms, with 53 novel, showing both concordant and discordant effects. GTEx analyses identified overexpression in multiple brain regions. Amygdala and caudate nucleus volumes were associated with AUD and BMI. Opposing variant effects explain the minimal rg between AUD and BMI, with implicated brain regions involved in executive function and reward, clarifying their polygenic overlap and neurobiological mechanisms.","PeriodicalId":19074,"journal":{"name":"Nature Human Behaviour","volume":"69 1","pages":""},"PeriodicalIF":29.9,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Socio-economic status is a social construct with heritable components and genetic consequences

IF 29.9 1区心理学

Nature Human Behaviour Pub Date : 2025-03-26 DOI: 10.1038/s41562-025-02150-4

Abdel Abdellaoui, Hilary C. Martin, Martin Kolk, Adam Rutherford, Michael Muthukrishna, Felix C. Tropf, Melinda C. Mills, Brendan P. Zietsch, Karin J. H. Verweij, Peter M. Visscher

{"title":"Socio-economic status is a social construct with heritable components and genetic consequences","authors":"Abdel Abdellaoui, Hilary C. Martin, Martin Kolk, Adam Rutherford, Michael Muthukrishna, Felix C. Tropf, Melinda C. Mills, Brendan P. Zietsch, Karin J. H. Verweij, Peter M. Visscher","doi":"10.1038/s41562-025-02150-4","DOIUrl":"https://doi.org/10.1038/s41562-025-02150-4","url":null,"abstract":"In civilizations, individuals are born into or sorted into different levels of socio-economic status (SES). SES clusters in families and geographically, and is robustly associated with genetic effects. Here we first review the history of scientific research on the relationship between SES and heredity. We then discuss recent findings in genomics research in light of the hypothesis that SES is a dynamic social construct that involves genetically influenced traits that help in achieving or retaining a socio-economic position, and can affect the distribution of genes associated with such traits. Social stratification results in people with differing traits being sorted into strata with different environmental exposures, which can result in evolutionary selection pressures through differences in mortality, reproduction and non-random mating. Genomics research is revealing previously concealed genetic consequences of the way society is organized, yielding insights that should be approached with caution in pursuit of a fair and functional society.","PeriodicalId":19074,"journal":{"name":"Nature Human Behaviour","volume":"1 1","pages":""},"PeriodicalIF":29.9,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143703115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

General anaesthesia decreases the uniqueness of brain functional connectivity across individuals and species

IF 29.9 1区心理学

Nature Human Behaviour Pub Date : 2025-03-24 DOI: 10.1038/s41562-025-02121-9

Andrea I. Luppi, Daniel Golkowski, Andreas Ranft, Rudiger Ilg, Denis Jordan, Danilo Bzdok, Adrian M. Owen, Lorina Naci, Emmanuel A. Stamatakis, Enrico Amico, Bratislav Misic

{"title":"General anaesthesia decreases the uniqueness of brain functional connectivity across individuals and species","authors":"Andrea I. Luppi, Daniel Golkowski, Andreas Ranft, Rudiger Ilg, Denis Jordan, Danilo Bzdok, Adrian M. Owen, Lorina Naci, Emmanuel A. Stamatakis, Enrico Amico, Bratislav Misic","doi":"10.1038/s41562-025-02121-9","DOIUrl":"https://doi.org/10.1038/s41562-025-02121-9","url":null,"abstract":"The human brain is characterized by idiosyncratic patterns of spontaneous thought, rendering each brain uniquely identifiable from its neural activity. However, deep general anaesthesia suppresses subjective experience. Does it also suppress what makes each brain unique? Here we used functional MRI scans acquired under the effects of the general anaesthetics sevoflurane and propofol to determine whether anaesthetic-induced unconsciousness diminishes the uniqueness of the human brain, both with respect to the brains of other individuals and the brains of another species. Using functional connectivity, we report that under anaesthesia individual brains become less self-similar and less distinguishable from each other. Loss of distinctiveness is highly organized: it co-localizes with the archetypal sensory–association axis, correlating with genetic and morphometric markers of phylogenetic differences between humans and other primates. This effect is more evident at greater anaesthetic depths, reproducible across sevoflurane and propofol and reversed upon recovery. Providing convergent evidence, we show that anaesthesia shifts the functional connectivity of the human brain closer to the functional connectivity of the macaque brain in a low-dimensional space. Finally, anaesthesia diminishes the match between spontaneous brain activity and cognitive brain patterns aggregated from the Neurosynth meta-analytic engine. Collectively, the present results reveal that anaesthetized human brains are not only less distinguishable from each other, but also less distinguishable from the brains of other primates, with specifically human-expanded regions being the most affected by anaesthesia.","PeriodicalId":19074,"journal":{"name":"Nature Human Behaviour","volume":"26 1","pages":""},"PeriodicalIF":29.9,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving mobility data for infectious disease research

IF 29.9 1区心理学

Nature Human Behaviour Pub Date : 2025-03-24 DOI: 10.1038/s41562-025-02151-3

Natalya Kostandova, Ronan Corgel, Shweta Bansal, Sophie Bérubé, Eimear Cleary, Chelsea Hansen, Matt D. T. Hitchings, Bernardo García-Carreras, Lauren Gardner, Moritz U. G. Kraemer, Shengjie Lai, Yao Li, Amanda C. Perofsky, Giulia Pullano, Jonathan M. Read, Gabriel Ribeiro dos Santos, Henrik Salje, Saki Takahashi, Cécile Viboud, Jasmine Wang, Derek A. T. Cummings, Amy Wesolowski

引用次数: 0

The synergy of embodied cognition and cognitive load theory for optimized learning

IF 29.9 1区心理学

Nature Human Behaviour Pub Date : 2025-03-21 DOI: 10.1038/s41562-025-02152-2

Liye Zou, Zhihao Zhang, Myrto Mavilidi, Yanxia Chen, Fabian Herold, Kim Ouwehand, Fred Paas

{"title":"The synergy of embodied cognition and cognitive load theory for optimized learning","authors":"Liye Zou, Zhihao Zhang, Myrto Mavilidi, Yanxia Chen, Fabian Herold, Kim Ouwehand, Fred Paas","doi":"10.1038/s41562-025-02152-2","DOIUrl":"https://doi.org/10.1038/s41562-025-02152-2","url":null,"abstract":"The integration of embodied cognition and cognitive load theory offers a promising framework for advancing educational practices. Cognitive load theory emphasizes the constraints of working memory and the importance of managing cognitive load through effective instructional design. Embodied cognition highlights the role of physical actions, such as gestures, object manipulation and whole-body activities, in enhancing cognitive processes. This Review highlights the importance of bridging these frameworks by exploring their theoretical foundations and synthesizing empirical evidence on the benefits of physical actions in learning. Here we present the introduction of the relevance–integration taxonomy as a transformative advancement in embodied cognition research, offering new perspectives for educational interventions. Additionally, we identify current gaps in cognitive load theory applications and propose future research directions to unify these approaches, aiming to optimize learning outcomes across diverse educational settings. This work has broad implications for advancing evidence-based instructional design.","PeriodicalId":19074,"journal":{"name":"Nature Human Behaviour","volume":"27 1","pages":""},"PeriodicalIF":29.9,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0