Chemical Senses最新文献

Olfaction and Diabetes Among Older Adults. 老年人的嗅觉和糖尿病。

IF 2.8 4区心理学

Chemical Senses Pub Date : 2025-06-18 DOI: 10.1093/chemse/bjaf020

Jingjing Xia, Yaqun Yuan, Chenxi Li, Anna Kucharska-Newton, Qu Tian, Jayant M Pinto, Jiantao Ma, Eleanor M Simonsick, Honglei Chen

{"title":"Olfaction and Diabetes Among Older Adults.","authors":"Jingjing Xia, Yaqun Yuan, Chenxi Li, Anna Kucharska-Newton, Qu Tian, Jayant M Pinto, Jiantao Ma, Eleanor M Simonsick, Honglei Chen","doi":"10.1093/chemse/bjaf020","DOIUrl":"https://doi.org/10.1093/chemse/bjaf020","url":null,"abstract":"Both poor olfaction and diabetes are common in older adults. It is biologically plausible that they may be related and interact to affect the health of older adults. We examined the association between poor olfaction and diabetes and their joint associations with mortality among 2416 older adults from the Health, Aging, and Body Composition Study. Olfaction was assessed at year 3 (1999-2000) using the Brief Smell Identification Test (B-SIT). We used year 4 (2000-2001) as study baseline and followed participants to year 11 (2007-2008) to identify incident diabetes and year 14 (2010-2011) to assess mortality. We used logistic regression to analyze the association of poor olfaction with prevalent diabetes and Cox proportional hazard models to assess its relationship to incident diabetes and its joint association with diabetes on mortality. Of the 2416 participants, 611 (25.3%) had diabetes at baseline and 138 (7.6%) developed incident diabetes during 6.4±1.7 years of follow-up. Compared to those with good olfaction, the odds ratio of prevalent diabetes was 1.11 (95% confidence interval/CI: 0.87-1.42) for those with poor olfaction, and the corresponding hazard ratio (HR) for incident diabetes was 1.01 (95%CI: 0.66-1.57). During 8.2±2.8 years of follow-up, 1007 (41.7%) participants died. Compared with participants without poor olfaction and diabetes, those with both were twice likely to die during the follow-up (HR=2.16, 95%CI: 1.71-2.73). However, we found no evidence for synergistic interaction (p=0.97). In conclusion, poor olfaction is not associated with the risk of diabetes, and these two conditions independently predict mortality in older adults.","PeriodicalId":9771,"journal":{"name":"Chemical Senses","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Common Scents? A review of potentially shared chemical signals in the Order Carnivora. 共同的气味吗?食肉目潜在的共同化学信号的综述。

IF 2.8 4区心理学

Chemical Senses Pub Date : 2025-06-09 DOI: 10.1093/chemse/bjaf019

Holly Root-Gutteridge, Neil de Kock, Madeleine Young, Andrew C Gill, Jake A Penny, Thomas W Pike, Daniel S Mills

{"title":"Common Scents? A review of potentially shared chemical signals in the Order Carnivora.","authors":"Holly Root-Gutteridge, Neil de Kock, Madeleine Young, Andrew C Gill, Jake A Penny, Thomas W Pike, Daniel S Mills","doi":"10.1093/chemse/bjaf019","DOIUrl":"https://doi.org/10.1093/chemse/bjaf019","url":null,"abstract":"Many animals transmit information in the form of chemical signals to modify behaviour or induce physiological change in receivers. For some taxa, such as species in the order Carnivora, chemical signals are known to provide a critical mode of communication, although they are still poorly understood compared to other signal modalities. Here, we review the literature to identify and categorise potential chemical signals within the Carnivora with a view to determining commonalities based on sex, taxon, and function. Data were drawn from 112 publications, dating from 1896-2021. Of the 1,532 discrete chemicals identified, 169 were detected in >5 species, with 58 found in ≥10 species. However, multiple different names were often used to report the same compound, reducing the transparency of the literature. 252 chemicals were identified as biomarkers, i.e., associated with specific behavioural contexts (dominance hierarchy, appeasement, agonistic, etc.) or specific demographic traits (age, sex, etc.). Few studies established a causal link between these biomarkers and behavioural or physiological changes, so only a few could be definitively described as behaviourally functional bioactive signals. We found high variability concerning which species, chemicals, and sources were represented in the literature, which could potentially lead to a perceptual bias in the relative importance of certain chemicals. Finally, we propose a method for standardised reporting of chemical signals and suggest that future work should focus on more consistent expansion of the range of species, products, and chemical types analysed, so that the phylogenetic relationship of chemical signals across taxa can be determined.","PeriodicalId":9771,"journal":{"name":"Chemical Senses","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The taste of trigeminal sensations: relation between taste, lingual tactile acuity, and spicy perception in patients with taste dysfunction. 三叉神经感觉的味觉：味觉功能障碍患者味觉、舌触觉敏锐度与辛辣感知的关系。

IF 2.8 4区心理学

Chemical Senses Pub Date : 2025-05-28 DOI: 10.1093/chemse/bjaf016

Mariano Mastinu, Max-Vincent Schönherr, Thomas Hummel

{"title":"The taste of trigeminal sensations: relation between taste, lingual tactile acuity, and spicy perception in patients with taste dysfunction.","authors":"Mariano Mastinu, Max-Vincent Schönherr, Thomas Hummel","doi":"10.1093/chemse/bjaf016","DOIUrl":"https://doi.org/10.1093/chemse/bjaf016","url":null,"abstract":"In the oral cavity, oral stereognosis and chemesthesis refer to the abilities to recognize shapes and detect noxious substances, respectively, through various receptors distributed on the tongue. The absence of standardized methods to assess oral somatosensory perception has led to a lack of consensus regarding the relationship between taste and trigeminal sensations. While some studies reported lower trigeminal perception in taste disorders, others did not confirm this correlation. In order to analyze somatosensation in quantitative and qualitative taste problems, 28 patients (21 females, mean age 59.2 years) with taste disturbance and 32 participants (20 females, mean age 42.3 years) with normogeusia identified 3D shapes and letters, sized from 2 to 18 mm, with the anterior part of their tongue, in a threshold test. Additionally, participants rated the intensity of increasing amounts of chili. Gustatory and olfactory functions were also tested. Analyses revealed that patients with taste dysfunction had significantly higher thresholds for lingual tactile sensitivity compared to controls (p < 0.001). Moreover, patients rated the intensity of chili significantly lower than controls (p < 0.001), particularly at higher concentrations. Oral stereognosis threshold scores were negatively correlated with gustatory and olfactory functions, and decreased with increasing age, while intensity for chili correlated with taste scores (p ≤ 0.009). The findings of this study suggest that taste dysfunction is associated with low oral mechanosensory and chemesthetic functions. The testing methods used in this study could be valuable in clinical practice for assessing and monitoring sensory impairments.","PeriodicalId":9771,"journal":{"name":"Chemical Senses","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of physical exercise and olfactory training with pleasant and unpleasant odors on verbal fluency and depression. 愉快气味和不愉快气味的体育锻炼和嗅觉训练对语言流畅性和抑郁的影响。

IF 2.8 4区心理学

Chemical Senses Pub Date : 2025-05-03 DOI: 10.1093/chemse/bjaf013

Agnieszka Sabiniewicz, Aleksandra Reichert, Anna Oleszkiewicz, Antje Hähner, Thomas Hummel

{"title":"Effects of physical exercise and olfactory training with pleasant and unpleasant odors on verbal fluency and depression.","authors":"Agnieszka Sabiniewicz, Aleksandra Reichert, Anna Oleszkiewicz, Antje Hähner, Thomas Hummel","doi":"10.1093/chemse/bjaf013","DOIUrl":"https://doi.org/10.1093/chemse/bjaf013","url":null,"abstract":"Mechanisms of olfactory training (OT) in older adults require a more thorough investigation, considering its potential beneficial effects in age-related olfactory, cognitive, and affective decline. To address this question, we examined the role of OT odor hedonics in 128 participants aged between 50 and 85 years (Mage = 68.2 ± 7.4; 105 women and 23 men). Additionally, we explored the role of physical activity in olfactory function, depression scores, and verbal fluency. Participants were randomly assigned to one of four groups, of which two performed OT with either a) pleasant or b) unpleasant odors, or c) performed physical exercises and no OT or d) a control group without OT or physical exercises. Results indicate a beneficial effect of OT, both with pleasant and unpleasant odors, on one key domain of cognitive function, namely verbal fluency. Furthermore, physical exercise alone also caused an increase in verbal fluency. Finally, a significant beneficial effect of OT on depression score was noted, but only in the group that displayed relatively robust depression symptoms in the pre-training session. OT may be of particular use for older people due to their risk of age-related cognitive decline and depression.","PeriodicalId":9771,"journal":{"name":"Chemical Senses","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Worldwide study of the taste of bitter medicines and their modifiers. 世界范围内对苦药及其改进剂味道的研究。

IF 2.8 4区心理学

Chemical Senses Pub Date : 2025-01-22 DOI: 10.1093/chemse/bjaf003

Ha Nguyen, Cailu Lin, Katherine Bell, Amy Huang, Mackenzie Hannum, Vicente Ramirez, Carol Christensen, Nancy E Rawson, Lauren Colquitt, Paul Domanico, Ivona Sasimovich, Riley Herriman, Paule Joseph, Oghogho Braimah, Danielle R Reed

{"title":"Worldwide study of the taste of bitter medicines and their modifiers.","authors":"Ha Nguyen, Cailu Lin, Katherine Bell, Amy Huang, Mackenzie Hannum, Vicente Ramirez, Carol Christensen, Nancy E Rawson, Lauren Colquitt, Paul Domanico, Ivona Sasimovich, Riley Herriman, Paule Joseph, Oghogho Braimah, Danielle R Reed","doi":"10.1093/chemse/bjaf003","DOIUrl":"10.1093/chemse/bjaf003","url":null,"abstract":"The bitter taste of medicines hinders patient compliance, but not everyone experiences these difficulties because people worldwide differ in their bitterness perception. To better understand how people from diverse ancestries perceive medicines and taste modifiers, 338 adults, European and recent US and Canadian immigrants from Asia, South Asia, and Africa, rated the bitterness intensity of taste solutions on a 100-point generalized visual analog scale and provided a saliva sample for genotyping. The taste solutions were 5 medicines, tenofovir alafenamide (TAF), moxifloxacin, praziquantel, amodiaquine, and propylthiouracil (PROP), and 4 other solutions, TAF mixed with sucralose (sweet, reduces bitterness) or 6-methylflavone (tasteless, reduces bitterness), sucralose alone, and sodium chloride alone. Bitterness ratings differed by ancestry for 2 of the 5 drugs (amodiaquine and PROP) and for TAF mixed with sucralose. Genetic analysis showed that people with variants in 1 bitter receptor variant gene (TAS2R38) reported PROP was more bitter than did those with a different variant (P = 7.6e-19) and that people with either an RIMS2 or a THSD4 genotype found sucralose more bitter than did others (P = 2.6e-8, P = 7.9e-11, respectively). Our findings may help guide the formulation of bad-tasting medicines to meet the needs of those most sensitive to them.","PeriodicalId":9771,"journal":{"name":"Chemical Senses","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innate liking and disgust reactions elicited by intraoral capsaicin in male mice. 雄性小鼠口服辣椒素引起的先天喜爱和厌恶反应。

IF 2.8 4区心理学

Chemical Senses Pub Date : 2025-01-22 DOI: 10.1093/chemse/bjaf006

Yibin Han, Daisuke H Tanaka, Naofumi Uesaka

{"title":"Innate liking and disgust reactions elicited by intraoral capsaicin in male mice.","authors":"Yibin Han, Daisuke H Tanaka, Naofumi Uesaka","doi":"10.1093/chemse/bjaf006","DOIUrl":"10.1093/chemse/bjaf006","url":null,"abstract":"Liking and disgust are the primary positive and negative emotions, respectively, and are crucial for nutrient intake and toxin avoidance. These emotions are induced by multimodal stimuli, such as taste, olfactory, and somatosensory inputs, and their dysregulation is evident in various psychiatric disorders. To understand the biological basis of liking and disgust, it is crucial to establish an animal model that allows for quantitative estimation of liking and disgust in response to multimodal stimuli. The only readout shared by many species, including humans, for liking and disgust, has been taste reactivity. However, readouts of non-taste stimuli-induced emotions remain unestablished. Here, we show that intraoral administration of capsaicin, a chemosomatosensory stimulus, elicits orofacial and bodily reactions in male mice similar to those observed in taste reactivity. Capsaicin-induced liking reactions at low concentrations and disgust reactions at high concentrations. Capsaicin-induced disgust reactions consisted of various reactions, including gape and forelimb flail, with the proportion of each reaction among the disgust reactions being similar to that induced by bitter and sour stimuli. These findings indicate that orofacial and bodily reactions, defined as taste reactivity, are elicited not only by taste stimuli but also by intraoral chemosomatosensory stimuli. Understanding the biological basis of capsaicin-induced orofacial and bodily reactions will advance our understanding of the fundamental mechanisms underlying liking and disgust across sensory modalities.","PeriodicalId":9771,"journal":{"name":"Chemical Senses","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical features of taste disorders in Cronkhite-Canada syndrome: a report of 10 cases. cronkite - canada综合征味觉障碍的临床特征（附10例报告）

IF 2.8 4区心理学

Chemical Senses Pub Date : 2025-01-22 DOI: 10.1093/chemse/bjae044

Tomomi Nin, Koji Kamikozuru, Tetsuya Takagawa, Shinichiro Shinzaki, Kenzo Tsuzuki

{"title":"Clinical features of taste disorders in Cronkhite-Canada syndrome: a report of 10 cases.","authors":"Tomomi Nin, Koji Kamikozuru, Tetsuya Takagawa, Shinichiro Shinzaki, Kenzo Tsuzuki","doi":"10.1093/chemse/bjae044","DOIUrl":"10.1093/chemse/bjae044","url":null,"abstract":"Cronkhite-Canada syndrome (CCS) is a very rare gastrointestinal disorder with ectodermal abnormalities. Taste abnormalities appear in more than 80% of cases. Our objective was to investigate the characteristics of CCS. Ten patients with taste abnormalities who were diagnosed with CCS were included. A medical interview, examination of the tongue findings, and blood tests were performed, and taste functions were assessed using an electrogustometry (EGM) and a filter paper disc (FPD) before and after treatment. There was nail atrophy in all cases, weight loss in 8 cases, hair loss in 6 cases, skin hyperpigmentation in 5 cases, gastrointestinal symptoms in 4 cases, and atrophy of the lingual papillae in at least 8 cases. Zinc therapy for taste disorders by the previous physicians was ineffective in all cases. The results of the FPD at the first examination showed a severe decrease in taste function of the anterior tongue, whereas taste function tended to be preserved in the posterior tongue (P < 0.01, Wilcoxon). In all cases, subjective symptoms improved within 3 mo after treatment of CCS. Taste function improved significantly after treatment (FPD in anterior tongue, P < 0.05, EGM in posterior tongue, P < 0.01, Wilcoxon). Taste disorder in CCS tended to be severe in the anterior tongue with findings of tongue papillary atrophy, which appears to be an ectodermal abnormality. Their taste function improved along with symptoms after treatment. The taste tests were useful for determining the effect of treatment for CCS.","PeriodicalId":9771,"journal":{"name":"Chemical Senses","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gustatory dysfunction in multiple sclerosis: a systematic review and meta-analysis. 多发性硬化症的味觉功能障碍：系统回顾和荟萃分析。

IF 2.8 4区心理学

Chemical Senses Pub Date : 2025-01-22 DOI: 10.1093/chemse/bjae046

Shahryar Rajai Firouzabadi, Ida Mohammadi, Mohammadreza Alinejadfard, Mohammad Yazdan Panah, Saeed Vaheb, Vahid Shaygannejad, Omid Mirmosayyeb

{"title":"Gustatory dysfunction in multiple sclerosis: a systematic review and meta-analysis.","authors":"Shahryar Rajai Firouzabadi, Ida Mohammadi, Mohammadreza Alinejadfard, Mohammad Yazdan Panah, Saeed Vaheb, Vahid Shaygannejad, Omid Mirmosayyeb","doi":"10.1093/chemse/bjae046","DOIUrl":"10.1093/chemse/bjae046","url":null,"abstract":"Gustatory dysfunction is an often overlooked symptom in people with multiple sclerosis (PwMS), potentially leading to poor appetite, malnutrition, weight loss, and decreased quality of life. This systematic review and meta-analysis aimed to assess the pooled prevalence of gustatory dysfunction in PwMS and compare their gustatory test scores with healthy controls. An online database search of PubMed, Embase, Scopus, and Web of Science was conducted on 2024 June 29. Observational studies reporting gustatory dysfunction or gustatory test scores in PwMS were included. Pooled prevalence rates were calculated using a random-effects model, with subgroup analyses based on the type of gustatory test used. Standardized mean differences (SMD) were calculated for comparisons between PwMS and healthy controls. A total of 9 studies encompassing 1385 PwMS were included. The pooled prevalence of gustatory dysfunction among PwMS was 16.4% (95% confidence intervals [95% CI]: 8.7% to 24.1%, I² = 90%, P < 0.01). Subgroup analysis showed a prevalence of 18.8% (95% CI: 10.5% to 27.2%, I² = 0%) in 4 studies using the Taste Strip Test (TST), while 3 non-TST studies using liquid tastants or self-reports reported a prevalence of 20.2% (95% CI: 7.2% to 33.3%, I² = 86%). PwMS had significantly lower gustatory test scores compared to healthy controls (SMD: -0.93, 95% CI: -1.20 to -0.65, I² = 0%, P = 0.48). Gustatory dysfunction affects a notable proportion of PwMS, with prevalence rates varying by assessment method. Future studies should assess the possible causes of gustatory dysfunction in PwMS using validated gustatory assessment scales.","PeriodicalId":9771,"journal":{"name":"Chemical Senses","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensory responses of olfactory and vomeronasal neurons in does are influenced by buck odors and their reproductive status. 雄鹿气味及其生殖状态影响雄鹿嗅觉神经元和犁鼻神经元的感觉反应。

IF 2.8 4区心理学

Chemical Senses Pub Date : 2025-01-22 DOI: 10.1093/chemse/bjaf012

Maxime A Meunier, Elliott Trives, Emma Gerardin, Chantal Porte, Adrien Acquistapace, Philippe Chemineau, Pablo Chamero, Hélène Vacher, Matthieu Keller

{"title":"Sensory responses of olfactory and vomeronasal neurons in does are influenced by buck odors and their reproductive status.","authors":"Maxime A Meunier, Elliott Trives, Emma Gerardin, Chantal Porte, Adrien Acquistapace, Philippe Chemineau, Pablo Chamero, Hélène Vacher, Matthieu Keller","doi":"10.1093/chemse/bjaf012","DOIUrl":"10.1093/chemse/bjaf012","url":null,"abstract":"In mammals, olfactory communication between conspecifics is crucial in modulating reproductive function. In anestrous does (i.e. female goats), exposure to hair from sexually active bucks (SAB, i.e. male goats) triggers a luteinizing hormone response that may induce ovulation, the \"male effect.\" However, the chemicals in buck hair responsible for this effect and the sensory pathways used by the females to detect this information remain insufficiently understood. In this study, we investigated whether sensory cells from the main olfactory epithelium (MOE) and the vomeronasal organ (VNO) of does respond differently to olfactory stimuli from SAB versus wethers (CAS, i.e. castrated bucks) and how this response is influenced by the female reproductive status (breeding season, anestrous, or ovariectomized (OVX)). To explore this possibility, we stimulated freshly dissociated cells of MOE and VNO cells with chloroform/methanol and aqueous extractions from buck hair, and we assessed cell activation using calcium imaging. Regardless of the extraction method, we observed more cells activated by SAB hair compounds than by those from CAS males. More MOE cells from anestrous were activated by both chloroform and aqueous extracts from SAB than MOE cells from breeding season, or OVX does. Most of these responses originated from non-mature olfactory neurons. These findings suggest that females can discriminate buck sexual activity through sensory detection by the MOE and VNO. The increased response in the MOE to SAB hair compounds during the anestrous period suggests that the MOE may play a more significant role in the \"male effect\" during this period.","PeriodicalId":9771,"journal":{"name":"Chemical Senses","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A cognitive nose? Evaluating working memory benchmarks in the olfactory domain. 认知鼻子？评估嗅觉领域的工作记忆基准。

IF 2.8 4区心理学

Chemical Senses Pub Date : 2025-01-22 DOI: 10.1093/chemse/bjaf008

Theresa L White, Nira Cedres, Jonas K Olofsson

{"title":"A cognitive nose? Evaluating working memory benchmarks in the olfactory domain.","authors":"Theresa L White, Nira Cedres, Jonas K Olofsson","doi":"10.1093/chemse/bjaf008","DOIUrl":"10.1093/chemse/bjaf008","url":null,"abstract":"Working memory (WM) processes are assumed to operate on a wide variety of sensory materials, yet WM research rarely extends beyond sight and hearing. In this systematic review, we integrate research from studies that address WM in olfaction, the sense of smell, spanning the last 50 yr (N = 44). We assessed whether 21 proposed \"benchmarks\" for WM generalize to olfactory WM. Seven benchmarks generalized to olfaction, whereas 2 failed to generalize. Evidence was insufficient to address the remaining 12 benchmarks (4 had mixed support and 8 were yet unaddressed). We conclude that the available evidence indicates that the sense of smell has a short-term memory system that mostly resembles WM processes in \"higher\" senses, although there are exceptions related to how olfactory WM performance is associated with other functions. We argue that researchers studying WM should explicitly consider evidence outside of the audio-visual senses when establishing theoretical frameworks. Further, we point out avenues for future research that may help close the remaining gaps in knowledge on this neglected topic.","PeriodicalId":9771,"journal":{"name":"Chemical Senses","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11985691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143584864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0