Psychophysiology最新文献

Causal Contributions and Interhemispheric Interactions of the Left and Right Supramarginal Gyri in Vocal Feedback Control: Insights From Dual-Site Transcranial Magnetic Stimulation. 声音反馈控制中左右边缘上回的因果贡献和半球间相互作用：来自双点经颅磁刺激的见解。

IF 2.9 2区心理学

Psychophysiology Pub Date : 2025-04-01 DOI: 10.1111/psyp.70054

Bo Peng, Ke Dong, Qingqing Liu, Jiating Li, Yan Zhao, Xin Huang, Mingyun Chen, Xiuqin Wu, Guangyan Dai, Dongxu Liu, Yongxue Li, Jingting Li, Xi Chen, Peng Liu, Tingni Li, Hanjun Liu

{"title":"Causal Contributions and Interhemispheric Interactions of the Left and Right Supramarginal Gyri in Vocal Feedback Control: Insights From Dual-Site Transcranial Magnetic Stimulation.","authors":"Bo Peng, Ke Dong, Qingqing Liu, Jiating Li, Yan Zhao, Xin Huang, Mingyun Chen, Xiuqin Wu, Guangyan Dai, Dongxu Liu, Yongxue Li, Jingting Li, Xi Chen, Peng Liu, Tingni Li, Hanjun Liu","doi":"10.1111/psyp.70054","DOIUrl":"10.1111/psyp.70054","url":null,"abstract":"The bilateral supramarginal gyri (SMGs) have been implicated in sensorimotor control of speech production, yet their precise roles and interhemispheric interactions are poorly understood. This event-related potential study employed dual-site continuous theta burst stimulation (c-TBS) over the bilateral SMGs simultaneously to investigate their functional dynamics in vocal motor control. Following unilateral and bilateral c-TBS over the SMG as well as sham stimulation, participants vocalized the vowel sounds while exposed to unexpected pitch perturbations in auditory feedback. Unilateral real c-TBS paired with contralateral sham stimulation led to reduced vocal compensation magnitudes and latencies and decreased P2 responses compared to bilateral sham stimulation, with no differences between left and right SMG stimulation. Source localization revealed that decreased P2 responses following left SMG stimulation localized to left-lateralized dorsolateral prefrontal cortex, supplementary motor area, SMG, middle temporal gyrus, and temporo-parietal junction, whereas such decreases following right SMG stimulation involved left-lateralized primary motor cortex, premotor cortex, and middle temporal gyrus. These findings suggest that both SMGs are causally involved in vocal feedback control through distinct but interconnected networks. Surprisingly, dual-site c-TBS over the bilateral SMG did not alter vocal compensation or cortical activity, suggesting an interhemispheric balancing mechanism for fine-tuning vocal production. Our results offer novel insights into the bihemispheric coordination of auditory-vocal integration, highlighting potential treatment for speech disorders by modulating interhemispheric interactions.","PeriodicalId":20913,"journal":{"name":"Psychophysiology","volume":"62 4","pages":"e70054"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Fronto-Central Theta Oscillations in Inter-Sensory Selective Attention. 前额-中央θ波振荡在感觉间选择性注意中的作用。

IF 2.9 2区心理学

Psychophysiology Pub Date : 2025-04-01 DOI: 10.1111/psyp.70055

Audrey Murray, Yasmine Zerroug, Isabelle Soulières, Dave Saint-Amour

{"title":"The Role of Fronto-Central Theta Oscillations in Inter-Sensory Selective Attention.","authors":"Audrey Murray, Yasmine Zerroug, Isabelle Soulières, Dave Saint-Amour","doi":"10.1111/psyp.70055","DOIUrl":"https://doi.org/10.1111/psyp.70055","url":null,"abstract":"Selective attention supports top-down control by biasing information processing toward stimuli that are potentially relevant to the immediate goal. It has been recently proposed that theta band oscillations (~4-8 Hz) in the frontal midline regions are a key mechanism of endogenous selective attention. The current electroencephalography study investigated theta oscillatory dynamics using an inter-sensory cueing paradigm in which a symbolic cue indicated, on a trial-by-trial basis, the modality (visual or auditory) of the upcoming discrimination task. Time-frequency analyses were used to quantify phase- (evoked) and non-phase-locked (induced) fronto-central theta activity during preparatory attentional states. In a sample of 20 young adult participants, we found that those who relied on the cues to selectively attend to the sensory modality of the discrimination task performed more efficiently (i.e., faster and with greater accuracy) and presented greater non-phase-locked fronto-central theta power 200-400 ms post-cue onset. Moreover, greater non-phase-locked theta oscillations were associated with better behavioral performance. Secondary analyses on alpha oscillations revealed concomitant brain activity to theta with a pronounced decrease in alpha power in fronto-central regions, without significant effect on task performance. These findings suggest that increased non-phase-locked fronto-central theta oscillations are a neuronal correlate of preparatory attentional control and that the interplay of theta-alpha rhythms differentially contributes to attentional and perceptual aspects.","PeriodicalId":20913,"journal":{"name":"Psychophysiology","volume":"62 4","pages":"e70055"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Interoceptive Brain: Confidence Ratings and Accuracy Scores are Independently and Differently Associated With Task-Related Alpha Power During the Heartbeat Tracking Task. 内感受性大脑：在心跳追踪任务中，信心评级和准确性得分与任务相关的阿尔法能量独立且不同地相关。

IF 2.9 2区心理学

Psychophysiology Pub Date : 2025-04-01 DOI: 10.1111/psyp.70051

Christian Rominger, Andreas Fink, Corinna M Perchtold-Stefan, Laurenz Schlögl, Andreas R Schwerdtfeger

{"title":"The Interoceptive Brain: Confidence Ratings and Accuracy Scores are Independently and Differently Associated With Task-Related Alpha Power During the Heartbeat Tracking Task.","authors":"Christian Rominger, Andreas Fink, Corinna M Perchtold-Stefan, Laurenz Schlögl, Andreas R Schwerdtfeger","doi":"10.1111/psyp.70051","DOIUrl":"10.1111/psyp.70051","url":null,"abstract":"Cardiac interoception is important for health and can be assessed in terms of accuracy (IAcc) and sensibility (IS), at least. While IAcc measures the correspondence between recorded and perceived heartbeats, IS means the confidence in interoceptive perceptions during the task. The present study investigated if brain activity during the heartbeat tracking task is associated with IAcc as well as IS. Specifically, we were interested if task-related power (TRP) in the alpha band (8-12 Hz), known to indicate task-specific cognitive functions such as semantic, attentional, and sensory processes, is associated with IAcc and IS, respectively. In a sample of 30 participants, we found relatively higher TRP in the alpha band over left temporal and parietal areas (vs. right) during the interoception task. Furthermore, we observed a negative association between TRP in the alpha band and IS. Lower TRP in the alpha band might indicate that more pronounced cognitive and sensory processes are linked to higher IS. Furthermore, we found a positive effect for IAcc (independent from IS), which might indicate that more internal attention during the interoception task is beneficial for IAcc. We further discuss the findings in the context of methodological issues of the heartbeat tracking task. Taken together, the pattern of findings favors the investigation of task-related IS (i.e., confidence ratings) in combination with IAcc to gain a better access to interoceptive processes and to improve our understanding of the neural underpinnings of (cardiac) interoception.","PeriodicalId":20913,"journal":{"name":"Psychophysiology","volume":"62 4","pages":"e70051"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11962349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic and Environmental Influences on Fear Learning and Generalization. 遗传和环境对恐惧学习和泛化的影响。

IF 2.9 2区心理学

Psychophysiology Pub Date : 2025-04-01 DOI: 10.1111/psyp.70052

Christina M Sheerin, Ashlee A Moore, Chelsea Sawyers, Robert Kirkpatrick, John M Hettema, Roxann Roberson-Nay

{"title":"Genetic and Environmental Influences on Fear Learning and Generalization.","authors":"Christina M Sheerin, Ashlee A Moore, Chelsea Sawyers, Robert Kirkpatrick, John M Hettema, Roxann Roberson-Nay","doi":"10.1111/psyp.70052","DOIUrl":"10.1111/psyp.70052","url":null,"abstract":"Understanding how excessive fear responses develop and persist is critical. Research using laboratory models of fear learning offers valuable insights on etiology. In this study, the influence of genetic and environmental etiology of baseline startle response and fear learning was examined, focusing on fear acquisition and generalization processes using the fear conditioning paradigm measuring fear-potentiated startle (FPS) in a sample of adolescents and young adult twins (15-20 years old). Participants (N = 794) completed fear acquisition and generalization training that consisted of quasi-randomly presented rings of gradually increasing size. The extreme sizes served as conditioned danger cues (CS+) paired with electric shock as the unconditioned stimulus and conditioned safety cues (CS-), with rings of intermediary size serving as generalization stimuli. As an index of fear learning, FPS was measured using the magnitude of eyeblink startle reflex to a sound probe. Twin model estimates indicated that both pre-acquisition startle (startle probe responses to stimuli prior to conditioning) and FPS (startle probe responses after conditioning during acquisition and generalization) exhibited modest to moderate heritability (26%-43%), aligning with previous studies on FPS. We also observed that the genetic influences on FPS were highly correlated with pre-acquisition startle, indicating minimal genetic innovation on FPS. This finding implies that fear responses might be regulated, from a genetic perspective, by general startle response as opposed to specific fear-learning-related factors. We discuss the resulting implications for measurement of biomarkers for fear and anxiety disorders.","PeriodicalId":20913,"journal":{"name":"Psychophysiology","volume":"62 4","pages":"e70052"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anxiety Sensitivity and Intolerance of Uncertainty Uniquely Explain the Association of the Late Positive Potential With Generalized Anxiety Disorder Symptoms. 焦虑敏感性和不确定性耐受独特地解释了晚期阳性电位与广泛性焦虑障碍症状的关联。

IF 2.9 2区心理学

Psychophysiology Pub Date : 2025-04-01 DOI: 10.1111/psyp.70044

Matt R Judah, Hannah C Hamrick, Benjamin Swanson, Morgan S Middlebrooks, Grant S Shields

{"title":"Anxiety Sensitivity and Intolerance of Uncertainty Uniquely Explain the Association of the Late Positive Potential With Generalized Anxiety Disorder Symptoms.","authors":"Matt R Judah, Hannah C Hamrick, Benjamin Swanson, Morgan S Middlebrooks, Grant S Shields","doi":"10.1111/psyp.70044","DOIUrl":"10.1111/psyp.70044","url":null,"abstract":"Studies suggest that generalized anxiety disorder (GAD) symptoms are related to late positive potential (LPP) responses to negative images, suggesting greater attention. Anxiety sensitivity (AS) and intolerance of uncertainty (IU) are cognitive factors in GAD vulnerability that may be activated by negative stimuli, thereby explaining why the LPP and GAD symptoms are related. We examined whether AS and IU explain the association of the LPP with GAD symptoms. Eighty-seven (77% women) young adults viewed 60 negative and 60 neutral images. The LPP was examined using both frequentist and Bayesian approaches. This revealed unique indirect effects of the LPP on GAD symptoms through AS and IU. Neither indirect effect was stronger, and the indirect effects were present regardless of using frequentist or Bayesian analyses or quantifying the LPP using residual-based scores or difference scores. The indirect effects predicted not only GAD symptoms but social anxiety and depression as well, consistent with the role of AS and IU in transdiagnostic vulnerability. The findings support AS and IU as links that explain how attention to negative stimuli is related not only to GAD symptoms but to other internalizing symptoms as well.","PeriodicalId":20913,"journal":{"name":"Psychophysiology","volume":"62 4","pages":"e70044"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interpersonal Conversations Are Characterized by Increases in Respiratory Sinus Arrhythmia. 人际交谈以呼吸性窦性心律失常增加为特征。

IF 2.9 2区心理学

Psychophysiology Pub Date : 2025-03-01 DOI: 10.1111/psyp.70043

Nathan C Stuart, Brett J Peters, Peggy M Zoccola, Ashley Tudder, Jeremy P Jamieson

{"title":"Interpersonal Conversations Are Characterized by Increases in Respiratory Sinus Arrhythmia.","authors":"Nathan C Stuart, Brett J Peters, Peggy M Zoccola, Ashley Tudder, Jeremy P Jamieson","doi":"10.1111/psyp.70043","DOIUrl":"10.1111/psyp.70043","url":null,"abstract":"Multiple theoretical perspectives connect vagally mediated heart rate variability, or respiratory sinus arrhythmia (RSA), and self-regulatory and interpersonal processes. Together they suggest that self-regulatory effort and positive social experiences may lead to short-term increases in RSA, which in turn are related to adaptive emotional, social, and physical functioning. However, the extant literature on adult social interactions does not clearly support this premise. To study the connections between dyadic social interactions and phasic changes in RSA, the current research examined 356 dyads (712 adults between 18 and 36 years; 50% males, 50% females) across three studies in which participants engaged in face-to-face social interactions in a laboratory setting. Relationship type and conversation context varied across studies, and high-frequency power was used to estimate RSA across resting baseline, anticipatory periods, and conversation tasks. Analyses indicated that anticipation of and engagement in dyadic social interactions were associated with an increase in RSA from a resting baseline. The mean estimated effect size for anticipation was r = 0.50, and the mean estimated effect size for conversation was r = 0.34. Associations were robust across relationship types, including strangers and romantic couples, conversation context, including topic and valence, and across speaking and listening roles. The present research provides consistent evidence for increased RSA in anticipation of and during in-person social interactions among adults, prompting the need for further investigation into potential underlying mechanisms.","PeriodicalId":20913,"journal":{"name":"Psychophysiology","volume":"62 3","pages":"e70043"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11946932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of Adolescents With Major Depressive Disorder Using Random Forest Based on Nocturnal Heart Rate Variability. 基于夜间心率变异性的随机森林识别青少年重度抑郁症。

IF 2.9 2区心理学

Psychophysiology Pub Date : 2025-03-01 DOI: 10.1111/psyp.70049

Wanlin Chen, Haisi Chen, Haoxuan Ruan, Wenchen Jiang, Cheng Chen, Moya Xu, Yifei Xu, Hang Chen, Zhenghe Yu, Shulin Chen

{"title":"Identification of Adolescents With Major Depressive Disorder Using Random Forest Based on Nocturnal Heart Rate Variability.","authors":"Wanlin Chen, Haisi Chen, Haoxuan Ruan, Wenchen Jiang, Cheng Chen, Moya Xu, Yifei Xu, Hang Chen, Zhenghe Yu, Shulin Chen","doi":"10.1111/psyp.70049","DOIUrl":"https://doi.org/10.1111/psyp.70049","url":null,"abstract":"Major depressive disorder (MDD) in adolescents is often underdiagnosed, with the current diagnosis predominantly relying on subjective assessment. Sleep disturbance and reduced heart rate variability (HRV) have been typically observed in adolescents with MDD. This study aimed to develop an automatic classification model based on nocturnal HRV features to identify adolescent MDD. Sixty-three subjects, including depressed adolescents and healthy controls, participated in the study and completed a three-night sleep electrocardiogram (ECG) monitoring, yielding 160 overnight RR interval time series and 7520 5-min short-term segments for analysis. Nineteen HRV features were extracted from the time domain, frequency domain, and nonlinear dynamics. The Bayesian-optimized random forest (BO-RF) algorithm was applied as the classifier, with performance evaluated using ten-fold cross-validation. The impact of data accumulation on the reliability of identification using short-term data and the importance of features were also examined. The BO-RF classifier based on long-term features achieved a noteworthy predictive accuracy of 80.6%, and the performance of the classifier using short-term data showed a significant improvement when more segment outcomes from the same night were included, ultimately achieving an accuracy of 75.0%. The Poincaré plot-derived features, especially heart rate asymmetry (HRA) features such as C1d, significantly contributed to distinguishing depressed adolescents from healthy subjects. Nocturnal HRV features can effectively differentiate adolescents with MDD from healthy controls. This study provides a promising diagnostic approach for adolescent MDD, with the potential to be integrated into wearable devices for broader application.","PeriodicalId":20913,"journal":{"name":"Psychophysiology","volume":"62 3","pages":"e70049"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Amygdala Structure and Function: Association With Transdiagnostic Trauma Severity in Anxiety and Mood Disorder Patients. 杏仁核结构和功能：与焦虑和情绪障碍患者的跨诊断性创伤严重程度相关。

IF 2.9 2区心理学

Psychophysiology Pub Date : 2025-03-01 DOI: 10.1111/psyp.70027

Nicola Sambuco, Margaret M Bradley, Peter J Lang

{"title":"Amygdala Structure and Function: Association With Transdiagnostic Trauma Severity in Anxiety and Mood Disorder Patients.","authors":"Nicola Sambuco, Margaret M Bradley, Peter J Lang","doi":"10.1111/psyp.70027","DOIUrl":"10.1111/psyp.70027","url":null,"abstract":"Reductions in both the size of the amygdala and functional activity during emotional processing have been independently associated with trauma exposure and severity, raising the question of whether reduced volume prompts reduced functional activation. In this multimodal assessment, the relationship between amygdala structure and function was investigated in mood and anxiety patients to determine their covariation and their relationship to trauma magnitude. Overall, amygdala volume and functional emotional reactivity were unrelated, with smaller volumes and reduced emotional reactivity each independently predicting trauma magnitude for women, and mediation analysis did not support a hypothesis that the relationship between reduced functional activity and trauma severity depends on amygdala volume. Structural and functional differences were instead separately related to different facets of trauma experience, highlighting the need for longitudinal and multimodal analyses to further elucidate the relationship between brain structure, function, and psychopathology.","PeriodicalId":20913,"journal":{"name":"Psychophysiology","volume":"62 3","pages":"e70027"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Interplay of Spontaneous Pupil-Size Fluctuations and EEG Power in Near-Threshold Detection. 近阈值检测中瞳孔大小波动与脑电功率的相互作用。

IF 2.9 2区心理学

Psychophysiology Pub Date : 2025-03-01 DOI: 10.1111/psyp.70035

Veera Ruuskanen, C Nico Boehler, Sebastiaan Mathôt

引用次数: 0

Continuous Transcutaneous Auricular Vagus Nerve Stimulation Increases Long-Latency Neural Processing in Multiple Sensory Modalities. 连续经皮耳迷走神经刺激增加多种感觉模式的长潜伏期神经加工。

IF 2.9 2区心理学

Psychophysiology Pub Date : 2025-03-01 DOI: 10.1111/psyp.70048

Valentina Jelinčić, Martina D'Agostini, Carlos Ventura-Bort, Loriss Cascio, Ekaterina Gorianskaia, Mathias Weymar, Diana M Torta, Ilse Van Diest, Andreas von Leupoldt

{"title":"Continuous Transcutaneous Auricular Vagus Nerve Stimulation Increases Long-Latency Neural Processing in Multiple Sensory Modalities.","authors":"Valentina Jelinčić, Martina D'Agostini, Carlos Ventura-Bort, Loriss Cascio, Ekaterina Gorianskaia, Mathias Weymar, Diana M Torta, Ilse Van Diest, Andreas von Leupoldt","doi":"10.1111/psyp.70048","DOIUrl":"https://doi.org/10.1111/psyp.70048","url":null,"abstract":"Transcutaneous auricular vagus nerve stimulation (taVNS) is a noninvasive technique stimulating vagal afferent fibers, showing promise in treating neurological and mental disorders. taVNS is believed to activate the locus coeruleus (LC), promoting noradrenergic activation (NA), which enhances arousal and attention. However, evidence for the LC-NA hypothesis is mixed, and investigations in different sensory modalities are lacking. This study investigated whether continuous taVNS enhances standard NA markers along with neural processing in three sensory modalities (auditory, respiratory, and somatosensory). In a 2-day Sham-controlled crossover protocol, 45 healthy adults received taVNS at the cymba concha and Sham stimulation at the earlobe. During stimulation, participants experienced paired auditory clicks, inspiratory occlusions, and electrocutaneous stimuli, while EEG was acquired. Salivary alpha-amylase (sAA) and subjective experienced arousal were measured at pre-/end-stimulation. Resting-state EEG was measured pre-/poststimulation to assess alpha-band (8-13 Hz) oscillation power, and participants rated the intensity and unpleasantness of all stimuli. Auditory-, respiratory-related-, and somatosensory evoked potentials were measured, specifically P50, N1, and P2 components, as well as the P50/N1 amplitude difference of the second and the first stimulus in the pair (neural gating; S2-S1). Although no effects in P50 or N1 amplitudes were observed, P2 amplitudes in auditory and somatosensory blocks increased during taVNS. Self-reported arousal increased in the taVNS condition, with no effects on neural gating, sAA concentration, or resting-state alpha power. taVNS had no effect on self-reported intensity/unpleasantness of stimuli. These results highlight certain limitations posed by combining taVNS and EEG and underline the need for further mechanistic taVNS research.","PeriodicalId":20913,"journal":{"name":"Psychophysiology","volume":"62 3","pages":"e70048"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0