Journal of clinical and experimental neuropsychology最新文献

{"title":"Usability of the Mayo Test Drive remote self-administered web-based cognitive screening battery in adults aged 35-100 with and without cognitive impairment.","authors":"Jay S Patel, Teresa J Christianson, Logan T Monahan, Ryan D Frank, Winnie Z Fan, John L Stricker, Walter K Kremers, Aimee J Karstens, Mary M Machulda, Julie A Fields, Jason Hassenstab, Clifford R Jack, Hugo Botha, Jonathan Graff-Radford, Ronald C Petersen, Nikki H Stricker","doi":"10.1080/13803395.2025.2464633","DOIUrl":"10.1080/13803395.2025.2464633","url":null,"abstract":"<p><strong>Background: </strong>Mayo Test Drive (MTD): Mayo Test Development through Rapid Iteration, Validation and Expansion, is a web-based remote cognitive assessment platform for self-administered neuropsychological measures with previously demonstrated validity and reliability. We examined the usability of MTD and hypothesized that completion rates would be greater than 90%. We explored whether completion and participation rates differed by cognitive status and demographic factors.</p><p><strong>Methods: </strong>A total of 1,950 Mayo Clinic Study of Aging and Mayo Alzheimer's Disease Research Center participants (97% White, 99% Non-Hispanic) were invited to participate in this ancillary, uncompensated remote study. Most invitees were cognitively unimpaired (CU; <i>n</i> = 1,769; 90.7%) and 9.3% were cognitively impaired (CI; <i>n</i> = 181). Usability was objectively defined as the percentage of participants who completed a session after initiating a session for a given timepoint (i.e. completion rates).</p><p><strong>Results: </strong>Baseline session completion rates were 98.5% (<i>n</i> = 1199/1217 participants, mean age 71, SD = 12, range 35-100) and were comparable between CU (98.7%) and CI (95.0%) groups (<i>p</i> = .23). Completion rates did not significantly differ by age groups (<i>p</i> > .10) and remained high in individuals 80+ (<i>n</i> = 251, 97.3%). Participation rates were higher in the CU (<i>n</i> = 1142, 65.4%) versus CI (<i>n</i> = 57, 33.1%) group (<i>p</i> < .001); participants were younger and had more years of education (p's < .001). Adherence (i.e. retention) rate for a 7.5-month follow-up session was 89%. Average session duration was 16 min. Most participants used a personal computer (62.7%), followed by a smartphone (22.2%) or tablet (14.8%). Comments entered by 36.4% of participants reflected several themes including acceptability, face validity, usability, and comments informative for session context.</p><p><strong>Conclusions: </strong>MTD demonstrated high usability as defined by completion rates in this research sample that includes a broad age range, though participation rates are lower in individuals with cognitive impairment. Results support good adherence at follow-up, feasibility through mean session duration, and acceptability based on qualitative analysis of participant comments.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":" ","pages":"1-23"},"PeriodicalIF":1.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An embedded, event-based prospective memory task administered via telephone is associated with everyday functioning in healthy younger and older adults.","authors":"Jennifer L Thompson Kamar, Michelle A Babicz Boston, Troy A Webber, Luis D Medina, Steven Paul Woods","doi":"10.1080/13803395.2025.2469867","DOIUrl":"https://doi.org/10.1080/13803395.2025.2469867","url":null,"abstract":"<p><strong>Introduction: </strong>Prospective memory (PM) is a higher-order cognitive function that involves the ability to execute a future intention. PM is a clinically relevant construct for the neuropsychological assessment of older adults given its importance in everyday functioning and quality of life. However, there is a paucity of reliable and ecologically relevant PM tasks that are amenable to a telehealth environment. The current study examined whether an event-based PM task embedded throughout a psychological battery administered via telephone was associated with everyday functioning in healthy older and younger adults.</p><p><strong>Method: </strong>The study included 60 older (i.e. ages 50+) and 46 younger (i.e. ages 18-35) adults who completed a 90-minute telephone-based evaluation that included clinical measures of cognition, subjective cognitive symptoms, instrumental activities of daily living (ADL), and performance-based functional capacity. PM was measured by a four-trial task with focal, event-based cues embedded within the broader test battery.</p><p><strong>Results: </strong>Lower PM showed medium-to-large univariable associations with all three measures of everyday functioning in the full sample. Multiple regressions covarying for global cognitive functioning showed that PM was uniquely associated with instrumental ADL in older adults and with performance-based functional capacity in the full sample.</p><p><strong>Conclusions: </strong>These data provide preliminary support for the incremental, criterion validity of an embedded, telephone-based task of PM in relation to everyday functioning. Measurement of PM via telephone is feasible and may add value to standard neuropsychological assessment.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":" ","pages":"1-15"},"PeriodicalIF":1.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and reliability of the online useful field of view test among community-dwelling older adults.","authors":"Shannon K Runge, Elizabeth M Hudak, Jade A Sutfin, Victor R Dobrovolskiy, Jerri D Edwards","doi":"10.1080/13803395.2025.2461518","DOIUrl":"https://doi.org/10.1080/13803395.2025.2461518","url":null,"abstract":"<p><strong>Background: </strong>The Useful Field of View Test (UFOV®) is a widely used measure of processing speed and visual attention that predicts driving performance and other functional abilities among older adults. We examined the reliability and validity of a new UFOV® version adapted for online administration.</p><p><strong>Method: </strong>Community-dwelling older adults (<i>N</i> = 69, <i>M</i> = 73 years of age) completed the personal computer (PC) and online versions of the UFOV® at baseline and approximately 4 months later (registered at https://osf.io/7utgw). Participants also completed baseline measures of cognitive, motor, and visual function (i.e. Flanker, Timed Up and Go Test, and near visual acuity). Pearson correlations were used to examine the validity and reliability for the total and subtest scores of the online UFOV® version relative to the PC version. Convergent and divergent validity was examined by comparing correlations between both the UFOV® versions and measures of cognitive, motor, and visual function.</p><p><strong>Results: </strong>UFOV® total, divided attention, and selective attention subtest scores of the online and PC versions were significantly correlated with moderate to strong effect sizes, <i>r</i>s = 0.39-0.54, <i>p</i>s < .001, supporting evidence for the validity of the online version. The online and PC versions of UFOV® were similarly related to gait speed, indicating convergent validity. Both versions of the UFOV® were distinct from near visual acuity, indicating divergent validity. The online UFOV® total and selective attention subtest scores from baseline to posttest were significantly correlated, indicating test-retest reliability, <i>r</i>s = 0.64-0.72, <i>p</i>s ≤ .006. Lack of variability among processing speed subtest scores restricted analyses, as performance was highly consistent across time.</p><p><strong>Discussion: </strong>These data support the validity and reliability of the online UFOV®, particularly for the total and selective attention subtest scores. Future research should confirm the online UFOV® similarly predicts driving and other aspects of functional performance among older adults.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":" ","pages":"1-12"},"PeriodicalIF":1.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges and opportunities for a new era of neuropsychology training: a trainee survey study.","authors":"Joshua T Fox-Fuller, Amanda M Wisinger, Jacob W Koudys, Libby A DesRuisseaux, Brian Cerny, Taylor Rose Schmitt, Annalise Rahman-Filipiak, Kristen L Votruba","doi":"10.1080/13803395.2025.2464654","DOIUrl":"https://doi.org/10.1080/13803395.2025.2464654","url":null,"abstract":"<p><strong>Introduction: </strong>The field of neuropsychology is undergoing notable changes, especially in the context of the Minnesota Update Conference (MNC) guidelines draft development. In late 2023, a group of neuropsychology trainee-leaders, united through the Clinical Neuropsychology Trainee Forum (CNTF), surveyed neuropsychology trainees in the United States and Canada to better understand their needs and their perception of the current training climate.</p><p><strong>Method: </strong>Survey items were drafted by a CNTF task force consisting of trainee-leaders from major neuropsychology organizations before being refined by four independent neuropsychologists. The survey was distributed via listservs and social media. Survey results were analyzed using frequency descriptives and analyses of variance to compare differences in responses based on demographic and training-related factors.</p><p><strong>Results: </strong>Respondents who completed a majority of the survey (<i>n</i> = 220) were primarily female (86%), White (71%), and training in the United States (92%). More than 75% of respondents reported satisfaction with their doctoral program, internship, and/or fellowship. Similarly, 90% and 73% of the respondents, respectively, felt their opinions on the future of the field listened to and/or valued in discussions with peers and supervisors/mentors. However, only 57% of the respondents felt their opinions were valued by neuropsychology organizational leadership, and approximately 30% of the respondents agreed that trainees' opinions were valued during the MNC draft development review period. Another 40% of the respondents were uncertain about trainee perspectives being valued during the MNC process.</p><p><strong>Conclusions: </strong>Most neuropsychology trainees are satisfied with their training, yet they expressed concerns about their opinions on the future of the field being heard by neuropsychology leadership. Trainee stakeholder engagement will be important to the vitality of neuropsychology in light of anticipated MNC Guidelines. Recommendations for the field of neuropsychology to support trainees will be discussed.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":" ","pages":"1-14"},"PeriodicalIF":1.8,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trail making test - part B discontinuation is associated with worse performance across multiple cognitive domains, but not with psychological distress.","authors":"Ashley Heywood, Anna C Cichocki, Justin D Numerick, Madison M Dykins, Genevieve E Roth, Devin M Ulrich, Matthew S Phillips, Brian M Cerny, Gabriel P Ovsiew, Anthony D Robinson, Jason R Soble, Woojin Song, Neil H Pliskin, Kyle J Jennette","doi":"10.1080/13803395.2025.2464642","DOIUrl":"https://doi.org/10.1080/13803395.2025.2464642","url":null,"abstract":"<p><strong>Objective: </strong>Individuals unable to complete neuropsychological tests within designated time limits (i.e. discontinue) are often excluded from statistical analysis. However, discontinuation may represent a meaningful clinical consideration. The present study investigated the clinical utility of discontinuation on the Trail Making Test Part B (TMT-B) as an indicator of cognitive functioning.</p><p><strong>Method: </strong>The sample included 137 patients (<i>n</i> = 90 completers; <i>n</i> = 47 non-completers) referred for comprehensive outpatient neuropsychological evaluation for primary memory complaints. Mann-Whitney U tests and chi-square tests compared the characteristics of patients who did complete the TMT-B to patients who did not by social demographics, neuropsychological test performance, health literacy/numeracy, and self-report measures of psychological symptoms and functional impairment.</p><p><strong>Results: </strong>TMT-B discontinuation was associated with significant differences across nearly all cognitive domains (p-adj <.01), including worse performance on measures of language, processing speed, verbal and visual learning and memory, executive functions, nondominant hand fine motor speed/dexterity, and visuoconstruction. Differences between individuals who discontinued TMT-B based on social demographics, psychological symptoms, functional abilities, performance validity measures, dominant hand fine motor speed/dexterity, and basic auditory working memory were nonsignificant.</p><p><strong>Conclusions: </strong>Discontinuation on TMT-B is associated with significantly worse cognitive performance across nearly all domains of neuropsychological performance. Discontinuation was not associated with any specific clinical diagnosis. Discontinuation could be an indicator of cognitive impairment and may reflect the unique value of the TMT-B as a screening tool for determining appropriate clinical assessment batteries.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":" ","pages":"1-13"},"PeriodicalIF":1.8,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance invalidity in traumatic brain injury litigants with poor quality of education: a South African cross-cultural study.","authors":"Sharon Truter","doi":"10.1080/13803395.2025.2456045","DOIUrl":"https://doi.org/10.1080/13803395.2025.2456045","url":null,"abstract":"<p><p><b>Introduction:</b> Performance invalidity is under-studied in countries outside of the United States of America (US), with non-English examinees and with those who have low levels or poor quality of education.<b>Method:</b> This cross-cultural neuropsychological study explored performance invalidity in South African adult traumatic brain injury (TBI) litigants (N = 100) who had 7‒12 years of poor quality of education and who spoke Afrikaans (n = 35), English (n = 9) or one of the indigenous African languages of Xhosa (n = 52), Swahili (n = 1), Pedi (n = 1), Sotho (n = 1) and Chichewa (n = 1) as first languages.<b>Results:</b> Using demographically appropriate cutoff scores for seven performance validity tests (PVTs), the prevalence of performance invalidity was calculated as being close to 30% for this group. Participants who failed zero or one PVT were categorized as performing validly, while those who failed ≥ 2 PVTs were categorized as performing invalidly, raising suspicion of feigned cognitive impairment. Only 9% of the participants failed three or more PVTs. Severity of brain injury and the demographic factors of age and level of education did not play a significant role in PVT failure.<b>Conclusion:</b> Considering the prevalence rate and that South African psychologists now have access to PVTs with demographically appropriated cutoff scores, South African psychologists no longer have an excuse not to include PVTs in their test batteries, even with examinees who have severe TBI.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":" ","pages":"1-14"},"PeriodicalIF":1.8,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the cognitive bias scale and cognitive bias scale of scales to other personality assessment inventory validity scales for detecting noncredible memory dysfunction in a clinical veteran sample.","authors":"Ryan W Schroeder, Rachel K Bieu, Makenna Snodgrass","doi":"10.1080/13803395.2025.2464635","DOIUrl":"https://doi.org/10.1080/13803395.2025.2464635","url":null,"abstract":"<p><strong>Introduction: </strong>The Cognitive Bias Scale (CBS) and the three Cognitive Bias Scale of Scales (CB-SOS) were developed for the Personality Assessment Inventory (PAI) to assess for cognitive response bias in neuropsychological settings and populations. While cross-validation research to date has been supportive, the scales have yet to be validated in a clinically referred veteran sample.</p><p><strong>Method: </strong>Patients (<i>N</i> = 235) were clinically referred veterans who underwent neuropsychological evaluations. Individuals were classified into valid or invalid memory performance groups based on a criterion performance validity test. The CBS, the three CB-SOS, and multiple core and supplemental PAI symptom validity indices were examined.</p><p><strong>Results: </strong>Both the CBS and the three CB-SOS had large correlations with multiple over-report validity scales, and high concurrent elevation rates were observed across many of the over-report validity scales. The greatest area under the curve rates (i.e. .70 or above) were seen for the CBS, two of the CB-SOS, and one psychiatrically focused validity index. When maintaining specificity at ≥90%, the CBS and two of the CB-SOS demonstrated the best sensitivity rates (i.e. 28-29%).</p><p><strong>Conclusions: </strong>While the CBS and the three CB-SOS have strong positive relationships with psychiatrically-focused over-report validity indices, the CBS and two of the CB-SOS demonstrated the best classification accuracy rates for identifying noncredible memory impairment. The cutoff scores and classification accuracy findings are in line with other published research results, suggesting good generalization to a clinically referred veteran sample. Additional conclusions regarding other findings are drawn and discussed.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":" ","pages":"1-14"},"PeriodicalIF":1.8,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of self-rated resilience following traumatic brain injury.","authors":"Jacobus Donders, Acacia Redman, Ashley Trainor","doi":"10.1080/13803395.2025.2464638","DOIUrl":"https://doi.org/10.1080/13803395.2025.2464638","url":null,"abstract":"<p><strong>Introduction: </strong>Resilience reflects the capacity of persons to continue to function in a positive way in the context of adverse conditions. Prior research has suggested that resilience may affect emotional adjustment and quality of life after traumatic brain injury (TBI). The purpose of this investigation was to determine to what extent self-rated resilience influences cognitive test performance after TBI.</p><p><strong>Method: </strong>We conducted a retrospective analysis of data collected during routine clinical care over a period of about 3 years at a regional rehabilitation facility. Participants included 100 adult persons with TBI (46% uncomplicated mild injury, 32% complicated mild injury and 22% severe injury). They had been clinically referred and seen for an outpatient neuropsychological evaluation within 1-36 months post injury. Main measures included the Connor-Davidson Resilience Scale-10 (CD - RISC-10), Patient Health Questionnaire-9 (PHQ-9), General Anxiety Disorder-7 (GAD-7), and Trail MakingTest (TMT).</p><p><strong>Results: </strong>Self-rated resilience, as reflected in CD - RISC-10 ratings, had strong negative correlations with symptoms of depression (PHQ-9) and anxiety (GAD-7). As expected, worse injury severity, older age and lower education level were associated with worse performance on both parts of the TMT (all <i>p</i>'s< .03). Importantly, beyond those influences, self-rated resilience was also positively associated with TMT performance. However, this was the case only in those who had threshold levels of normal resilience.</p><p><strong>Conclusions: </strong>Across the range of TBI severity, resilience as self-rated on the CD - RISC-10 is strongly related to subjective symptoms of anxiety and depression. It does not have a linear relationship with objective cognitive test performance. Instead, a minimum level of normal resilience is needed in order for it to support cognition after TBI. Findings of sub-threshold levels of resilience would support interventions to boost it and thereby potentially improve outcomes.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":" ","pages":"1-13"},"PeriodicalIF":1.8,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The time has come: discussing the clinical neuropsychology provider's role in cultural respect and inclusion.","authors":"Veronica Bordes Edgar, Beatriz MacDonald, April D Thames, Shawn M McClintock","doi":"10.1080/13803395.2025.2455126","DOIUrl":"https://doi.org/10.1080/13803395.2025.2455126","url":null,"abstract":"<p><p>There has been both a national and global emphasis within the past 3 years to promote diversity, equity, inclusion (DEI), and cultural respect in healthcare and academia. One discipline and healthcare arena where this has been evident is the psychology field. Indeed, there has been rampant and widespread adoption and advancement of DEI and cultural respect across most of psychology. Unfortunately, not all psychology specialties have fully embraced DEI or focused on provider factors, one of which is clinical neuropsychology. Regarding DEI efforts and emphasis in clinical neuropsychology, the majority of research and education has primarily focused on patient demographic and neuropsychological test factors. While such patient demographic and test factors are important and merit significant attention, so too does the focus on the clinical neuropsychological provider. Unfortunately, the clinical neuropsychology specialty has provided little to no focus on the provider's role in DEI and cultural respect. The purpose of this critical review is to focus on the role of the clinical neuropsychologist and how it impacts DEI and cultural respect. Specifically, the review will inform the factors that impact the practice of clinical neuropsychology on the part of the provider including unconscious/implicit bias, diagnostic threat, and microaggressions. Also, the review will inform strategies to create a DEI responsive and culturally respectful clinical neuropsychological practice with the overarching goal to uncover the clinical neuropsychological role to advance and evolve the specialty through a DEI and culturally respectful lens. With considerable work completed in other aspects of DEI and cultural respect, the clinical neuropsychology specialty is well poised to now focus on the role of the provider. This focus can provide a constructive path forward to create new knowledge to advance the role of the provider to optimize overall clinical, research, and training practices.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":" ","pages":"1-18"},"PeriodicalIF":1.8,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-traumatic stress, sleep, and neurocognitive problems in children newly diagnosed with a pediatric brain tumor.","authors":"Eva A B Kremer-Hooft van Huijsduijnen, Juliette E M Greidanus-Jongejan, Martha A Grootenhuis, Raphaele R L van Litsenburg, Femke K Aarsen, Niels E Franke, Evelien de Vos-Kerkhof, Marita Partanen","doi":"10.1080/13803395.2024.2426621","DOIUrl":"10.1080/13803395.2024.2426621","url":null,"abstract":"<p><strong>Background: </strong>Children diagnosed with brain tumors are at risk to develop neurocognitive problems. Post-traumatic stress and sleep have been associated with poorer neurocognitive outcomes in the general population, and could be potential targets for intervention in brain tumor patients. Therefore, this study examined neurocognitive functioning in children newly diagnosed with a brain tumor and the associations between posttraumatic stress and sleep with neurocognitive outcomes.</p><p><strong>Methods: </strong>Children 6-16 years old who were newly diagnosed with a brain tumor completed questionnaires on post-traumatic stress and sleep, actigraphy for sleep, and tests for neurocognitive outcomes. One-sample <i>t</i>-tests and chi-square tests were used to compare neurocognitive scores with age norms. Multivariable regression examined associations between post-traumatic stress, sleep, demographics, and medical factors associated with neurocognitive functioning.</p><p><strong>Results: </strong>Of all eligible children, 60 patients with newly diagnosed brain tumors were included, at an average of 51 days after diagnosis (67% male, mean = 11.5 years at diagnosis). Compared to age norms, patients with brain tumors scored lower on measures of attention, inhibition, and verbal memory (meanZ = -0.40 to -0.98, <i>p</i> < .05). History of obstructive hydrocephalus was associated with poorer attention (<i>p</i> < .05) and processing speed (<i>p</i> < .05), posterior fossa tumor location was associated with poorer working memory (<i>p</i> < .01), and starting chemotherapy or radiotherapy treatment before the assessment was associated with poorer verbal memory (<i>p</i> < .05). Post-traumatic stress and sleep were not associated with neurocognitive outcomes at this phase (<i>p</i> > .20).</p><p><strong>Conclusion: </strong>A subgroup of children with newly diagnosed brain tumors shows deficits in neurocognitive functioning, which highlights the importance of early monitoring to identify children at-risk for problems. Hydrocephalus, posterior fossa tumor location, and starting treatment, but not post-traumatic stress and sleep, are associated with poorer neurocognitive performance at this phase. Longitudinal research will be important for identifying biopsychosocial factors that may be associated with cognition over time.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":" ","pages":"1-13"},"PeriodicalIF":1.8,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}