Journal of clinical and experimental neuropsychology最新文献

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A case of severe anterograde amnesia in the era of smartphone technology. 智能手机技术时代的一例严重顺行性健忘症。
IF 2.2 4区 心理学
Journal of clinical and experimental neuropsychology Pub Date : 2023-08-01 Epub Date: 2023-11-09 DOI: 10.1080/13803395.2023.2254911
Jacopo Annese, Ruth Klaming, Lori Haase Alasantro, Justin S Feinstein
{"title":"A case of severe anterograde amnesia in the era of smartphone technology.","authors":"Jacopo Annese, Ruth Klaming, Lori Haase Alasantro, Justin S Feinstein","doi":"10.1080/13803395.2023.2254911","DOIUrl":"10.1080/13803395.2023.2254911","url":null,"abstract":"<p><p>A.V. is a young herpes simplex encephalitis (HSE) survivor who suffered extensive bilateral damage to the medial temporal lobe (MTL) leading to a severe and pervasive form of anterograde amnesia. Structural Magnetic Resonance Imaging (MRI) revealed lesions that encompass the hippocampus and amygdala in both hemispheres and that extend more laterally in the right temporal lobe. At the same time, detailed neuropsychological testing showed that the disparity between A.V.'s preserved intellectual functioning (Full Scale IQ: 115) and severe memory deficit (Delayed Memory Index: 42) is one of the largest on record. Despite this deficit, A.V. has regained a higher level of functioning and autonomy compared to previously documented amnesic cases with major bilateral MTL lesions. As a millennial, one advantage which A.V. has over prior amnesic cases is fluency with digital technology - particularly the smartphone. The analysis of his phone and specific app usage showed a pattern that is consistent with the strategy to offload cognitive tasks that would normally be supported by the MTL. A.V.'s behavior is significant in terms of rehabilitation and may have broader implications at the societal level and for public health given the ubiquity of smartphone technology and its potential to become integrated with neural mnemonic functions.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71424020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurocognitive and self-reported psychosocial and behavioral functioning in siblings of individuals with neurodevelopmental conditions: a study using remote self-administered testing. 患有神经发育疾病的个体的兄弟姐妹的神经认知和自我报告的心理社会和行为功能:一项使用远程自我管理测试的研究。
IF 2.2 4区 心理学
Journal of clinical and experimental neuropsychology Pub Date : 2023-08-01 Epub Date: 2023-11-09 DOI: 10.1080/13803395.2023.2259042
Brittany Wolff, Vithor Rosa Franco, Iliana Magiati, Carmela F Pestell, Emma J Glasson
{"title":"Neurocognitive and self-reported psychosocial and behavioral functioning in siblings of individuals with neurodevelopmental conditions: a study using remote self-administered testing.","authors":"Brittany Wolff, Vithor Rosa Franco, Iliana Magiati, Carmela F Pestell, Emma J Glasson","doi":"10.1080/13803395.2023.2259042","DOIUrl":"10.1080/13803395.2023.2259042","url":null,"abstract":"<p><strong>Objective: </strong>This study compared and explored the neurocognitive profiles of siblings of persons with and without neurodevelopmental conditions (NDCs) and associations between objective test performance and self-reported psychosocial functioning.</p><p><strong>Methods: </strong>Siblings of persons with and without NDCs (64 NDC and 64 control siblings; mean age 19.88 years, range 11-27 years, 73.44% female, 75.78% White Caucasian) completed self-report questionnaires and self-administered computerized neurocognitive tests of executive functioning (EF). Using Bayesian analyses, we examined cross-sectional associations between self-reported psychosocial functioning and cognitive test performance, and predictors of EF over 15 months.</p><p><strong>Results: </strong>NDC siblings had poorer working memory, inhibition, attention, and shifting compared to controls, as measured by experimental paradigms on the backward Corsi span, N-Back 2-back task, Stop Signal Task, Sustained Attention to Response Task, and the Wisconsin Card Sorting Test (effect size δ ranging 0.49 to 0.64). Bayesian cross-sectional networks revealed negative emotion reactivity and working memory difficulties were central to the NDC sibling network. Over 15 months, poorer EF (<i>k</i> low test scores) was predicted by negative emotion reactivity, sleep problems, and anxiety, over and above effects of age and subclinical autistic and ADHD traits. Siblings of autistic individuals and persons with fetal alcohol spectrum disorder had higher rates of neurocognitive and psychiatric difficulties than other NDCs and controls (Bayes factors >20).</p><p><strong>Conclusions: </strong>Neurocognitive difficulties were associated with transdiagnostic vulnerability to poorer wellbeing in NDC siblings. These findings demonstrate the feasibility of remote online cognitive testing and highlight the importance of individualized prevention and intervention for NDC siblings.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41121762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methadone maintenance treatment and impulsivity: premature responding. 美沙酮维持治疗和冲动:过早反应。
IF 2.2 4区 心理学
Journal of clinical and experimental neuropsychology Pub Date : 2023-08-01 Epub Date: 2023-12-29 DOI: 10.1080/13803395.2023.2276483
Kathrin Weidacker, Yijie Zhao, Yingying Zhang, Seb Whiteford, Qihuan Ren, Chencheng Zhang, Valerie Voon
{"title":"Methadone maintenance treatment and impulsivity: premature responding.","authors":"Kathrin Weidacker, Yijie Zhao, Yingying Zhang, Seb Whiteford, Qihuan Ren, Chencheng Zhang, Valerie Voon","doi":"10.1080/13803395.2023.2276483","DOIUrl":"10.1080/13803395.2023.2276483","url":null,"abstract":"<p><strong>Introduction: </strong>Previous research showed that methadone maintenance treatment (MMT) is linked to impulsivity, with higher impulsivity levels being associated with for example, increased drug use. One aspect of impulsivity, most commonly studied in rodent research, is premature responding, the failure to wait for a starting signal. Premature responding is of high translational significance since it predicts the development of addiction-like behaviors in rodents.</p><p><strong>Methods: </strong>We assessed 45 MMT patients and 46 demographically matched (age, sex, education, and handedness) healthy volunteers (HVs) on premature responding alongside action and inhibition of instructed and intentional trials using the Intentional Hand Task (IHT).</p><p><strong>Results: </strong>The results showed markedly enhanced premature responses in the MMT vs. the HV group, which correlated positively with methadone dosage in the MMT patients. Throughout the task, MMT patients were faster across all trial parts and less accurate in response to instructed trials compared to HVs.</p><p><strong>Conclusions: </strong>The increase in premature motor reactions during variable waiting periods alongside increased motion speed and lower accuracy might reflect a specific motor inhibition deficit in MMT, a subcomponent of impulsivity not previously assessed in MMT. Incorporating an experimentally defined measure of impulsivity, such as premature responding, into existing test batteries used by clinicians might enable more tailored treatments addressing the increased impulsivity levels and associated dysfunctional behaviors in MMT.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71424021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring expected reward and efficacy in enhancing cognitive control in patients with depression. 探讨预期奖励在增强抑郁症患者认知控制中的作用。
IF 2.2 4区 心理学
Journal of clinical and experimental neuropsychology Pub Date : 2023-08-01 Epub Date: 2023-12-29 DOI: 10.1080/13803395.2023.2287782
Mostafa Toobaei, Mohammadreza Taghavi, Mohammad Ali Goodarzi, Mehdireza Sarafraz, Laura Jobson
{"title":"Exploring expected reward and efficacy in enhancing cognitive control in patients with depression.","authors":"Mostafa Toobaei, Mohammadreza Taghavi, Mohammad Ali Goodarzi, Mehdireza Sarafraz, Laura Jobson","doi":"10.1080/13803395.2023.2287782","DOIUrl":"10.1080/13803395.2023.2287782","url":null,"abstract":"<p><strong>Background: </strong>Depression is associated with impairments in cognitive control. Considering the lack of mechanistic models accounting for cognitive control deficits in depression, the expected value of control (EVC) theory offers a mechanistic view for allocating cognitive control emphasizing motivational components (efficacy, value). Efficacy refers to the possibility that an effort leads to a special outcome and reward refers to the value (amount) associated with the outcome. This study aimed to examine the role of the EVC in depression.</p><p><strong>Method: </strong>This study used a within-between-subject design. Participants with depression (<i>n</i> = 36) and healthy controls (<i>n</i> = 31) completed a clinical diagnostic interview, the Beck Depression Inventory-II, the General Health Questionnaire-12, and a computer-based incentivized Stroop Color-Word Paradigm in which levels of efficacy (high vs. low) and the amount of rewards (high vs. low) were presented as cues before target stimuli.</p><p><strong>Results: </strong>We found significant interaction effects of group × efficacy and efficacy × reward in terms of reaction time in the Stroop Paradigm. Follow-up analyses indicated the Depressed group were significantly slower than Controls on high efficacy trials, but the two groups did not differ significantly on low efficacy trials. Additionally, on high efficacy trials, reward did not influence performance, but on low efficacy trials, high reward improved performance in both groups.</p><p><strong>Limitation: </strong>Lack of neurological measures and eye tracking techniques.</p><p><strong>Conclusion: </strong>Overall, our findings suggest that reward and efficacy may jointly improve cognitive control allocation and highlight the need for further research examining EVC theory as a mechanistic account of cognitive control deficits in depression.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138498525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimising verbal fluency analysis in neurological patients with dysarthria: examples from Parkinson's disease and hereditary ataxia. 优化神经系统构音障碍患者的语言流畅性分析:来自帕金森病和遗传性共济失调的例子。
IF 2.2 4区 心理学
Journal of clinical and experimental neuropsychology Pub Date : 2023-08-01 Epub Date: 2023-09-01 DOI: 10.1080/13803395.2023.2249172
Yanjun Li, Jihyun Yang, Kristine Evans, Jasmine Bow-Wah Wong, Nadeeka N Dissanayaka, Adam P Vogel
{"title":"Optimising verbal fluency analysis in neurological patients with dysarthria: examples from Parkinson's disease and hereditary ataxia.","authors":"Yanjun Li, Jihyun Yang, Kristine Evans, Jasmine Bow-Wah Wong, Nadeeka N Dissanayaka, Adam P Vogel","doi":"10.1080/13803395.2023.2249172","DOIUrl":"10.1080/13803395.2023.2249172","url":null,"abstract":"<p><strong>Background: </strong>Verbal fluency tests (VFTs) are widely used to assess cognitive-linguistic performance in neurological diseases. However, the influence of dysarthria on performance in tests requiring oral responses is unclear in ataxia and Parkinson's disease.</p><p><strong>Objectives: </strong>To determine the impact of dysarthria on VFT performance and evaluate the validity and reliability of alternative methods for analyzing VFT data.</p><p><strong>Method: </strong>Trained raters evaluated dysarthria using VFT recordings in people with ataxia (N = 61) or Parkinson's disease (PD; N = 69). Total Correct Items scores and qualitative parameters (intrusions, ambiguous verbalizations, perseverations, and interjections) were compared across semantic, phonemic, and alternating fluency tasks. Disease severity was considered as a covariate in the regression model.</p><p><strong>Results: </strong>VFT dysarthria ratings correlated with the benchmark (ground truth) dysarthria scores derived from a monologue. Ambiguous responses resulting from unclear speech impeded the rater's ability to determine if a response was correct. Regression analysis indicated that more severe dysarthria ratings predicted diminished scores in all three tasks (semantic fluency, phonemic fluency and alternating fluency) in the ataxia group. The contribution of disease severity to semantic, phonemic and alternating fluency was reduced substantially in the ataxia group after accounting for dysarthria severity in the model in both groups.</p><p><strong>Conclusions: </strong>Dysarthria severity can be estimated based on speech samples derived from VFT. Dysarthria can lead to lower total correct items and is associated with more ambiguous verbalizations in VFT. Dysarthria severity should be considered when interpreting VFT performance in common movement disorders.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10132601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance on a virtual environment shopping task and adaptive functioning among older adults. 老年人在虚拟环境购物任务中的表现和适应功能。
IF 2.2 4区 心理学
Journal of clinical and experimental neuropsychology Pub Date : 2023-08-01 Epub Date: 2023-08-28 DOI: 10.1080/13803395.2023.2249175
Michael D Barnett, Danielle R Hardesty, Rebekah A Griffin, Thomas D Parsons
{"title":"Performance on a virtual environment shopping task and adaptive functioning among older adults.","authors":"Michael D Barnett, Danielle R Hardesty, Rebekah A Griffin, Thomas D Parsons","doi":"10.1080/13803395.2023.2249175","DOIUrl":"10.1080/13803395.2023.2249175","url":null,"abstract":"<p><p>Neuropsychologists are often asked to evaluate patients' functional capacities, yet traditional neuropsychological tests have limited correspondence with real-world outcomes. The Virtual Environment Grocery Store (VEGS) is a virtual environment that simulates shopping tasks. The purpose of this study was to investigate the relationship between older adults' performance on the VEGS in relation to their self-reported adaptive functioning as well as performance on a performance-based adaptive functioning measure. Older adults (<i>n</i> = 98; age 65-90, <i>M</i> = 75.82, <i>SD </i>= 6.27) were administered the VEGS, the Instrumental Activities of Daily Living Scale (IADLS), and the Texas Functional Living Scale (TFLS). Neither premorbid functioning nor the VEGS variables were associated with self-rated adaptive functioning. However, all three VEGS variables were associated with performance-based adaptive functioning (i.e., the TFLS). Performance on the VEGS measure of correct items in the shopping cart explained 13.9% of the variance in performance on the performance-based adaptive functioning task. Whether the participant picked up the VEGS prescription explained 12.6% of the variance in performance on the performance-based adaptive functioning task. Performance on VEGS long delay free recall explained 35.1% of the variance in performance on the performance-based adaptive functioning task. These results suggest that the VEGS demonstrates value in predicting older adults' functional capacities.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10139791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Creative thinking in Tourette's syndrome: A comparative study of patients and healthy controls. 图雷特综合征患者与健康对照的创造性思维比较研究
IF 2.2 4区 心理学
Journal of clinical and experimental neuropsychology Pub Date : 2023-08-01 Epub Date: 2023-09-05 DOI: 10.1080/13803395.2023.2251644
Laura Colautti, Sara Magenes, Sabrina Rago, Stefania Camerin, Carlotta Zanaboni Dina, Alessandro Antonietti, Alice Cancer
{"title":"Creative thinking in Tourette's syndrome: A comparative study of patients and healthy controls.","authors":"Laura Colautti, Sara Magenes, Sabrina Rago, Stefania Camerin, Carlotta Zanaboni Dina, Alessandro Antonietti, Alice Cancer","doi":"10.1080/13803395.2023.2251644","DOIUrl":"10.1080/13803395.2023.2251644","url":null,"abstract":"<p><strong>Introduction: </strong>Tourette's syndrome is a neurological disorder characterized by tics, that may interfere with patients' everyday life. Research suggested that creative thinking (namely, divergent and convergent thinking) could help patients cope with their symptoms, and therefore it can be a resource in non-pharmacological interventions. The present study aimed at investigating (i) possible differences in creative thinking between Tourette's syndrome patients and healthy controls and (ii) whether creative thinking can support patients in coping with their symptomatology.</p><p><strong>Methods: </strong>A group of 25 Tourette's syndrome patients and 25 matched healthy controls underwent an assessment of creative thinking, fluid intelligence, and depressive symptoms. Creative thinking was compared between patients and healthy controls after controlling for fluid intelligence and depressive symptoms. Moreover, the moderating role of divergent and convergent thinking on the subjective impact of tics was tested in a group of 30 patients.</p><p><strong>Results: </strong>Tourette's syndrome patients outperformed healthy controls in convergent thinking. Moreover, divergent thinking was found as a significant moderator of the relationship between tics severity and the subjective impact in Tourette's syndrome patients.</p><p><strong>Conclusions: </strong>Findings highlighted the specific impact of convergent and divergent thinking on Tourette's syndrome patients. Considering the supportive role of creative thinking in Tourette's syndrome, our results confirm that higher levels of divergent thinking may reduce the tic-related discomfort. These findings suggest the potential positive implications of creative thinking in non-pharmacological interventions for Tourette's syndrome.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10153486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A pilot examination of the validity of stylus and finger drawing on visuomotor-mediated tests on ACEmobile. 手写笔和手指绘图在ACEmobile视觉运动介导测试中有效性的试点检验。
IF 2.2 4区 心理学
Journal of clinical and experimental neuropsychology Pub Date : 2023-08-01 Epub Date: 2023-08-24 DOI: 10.1080/13803395.2023.2249167
Rupert Noad, Craig Newman, Jade Chynoweth, Jacob Mayers, Stephen Hall, Donnchadh Murphy
{"title":"A pilot examination of the validity of stylus and finger drawing on visuomotor-mediated tests on ACEmobile.","authors":"Rupert Noad, Craig Newman, Jade Chynoweth, Jacob Mayers, Stephen Hall, Donnchadh Murphy","doi":"10.1080/13803395.2023.2249167","DOIUrl":"10.1080/13803395.2023.2249167","url":null,"abstract":"<p><strong>Introduction: </strong>Cognitive assessments, such as the Addenbrooke's Cognitive Examination (ACE-III) and Montreal Cognitive Assessment (MoCA), have been modified for administration using tablet computers. While this offers important advantages for practice, it may also threaten the test validity. The current study sought to test whether administering visuospatial and writing tests using a tablet (finger or stylus drawing), would demonstrate equivalence to traditional pencil and paper administration on ACEmobile.</p><p><strong>Method: </strong>This study recruited 26 participants with Alzheimer's disease and 23 healthy older adults. Most participants had low familiarity with using a tablet computer. Participants completed ACEmobile in its entirety, after which they repeated the infinity loops, cube, and clock drawing and sentence writing tests by drawing with a stylus and their finger onto an iPad. Performance on the drawing and writing tests using a stylus, finger, and pencil were compared.</p><p><strong>Results: </strong>Statistically significant differences were observed between the finger and pencil administration on the ACEmobile, with participants performing worse on the finger drawing trials. Differences in scores were most apparent on the sentence writing task. In contrast, no statistical differences were observed between the pencil and stylus administration.</p><p><strong>Discussion: </strong>The findings of this pilot study have important implications for clinical neuropsychology and demonstrate that administering ACEmobile drawing tests with finger drawing is invalid. However, due to the small sample size, a lack of counterbalancing and the narrow range of scores of the dependent variable, we are unable to confidently interpret the validity of stylus drawing. This is an important consideration for future research.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10423143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of the Spanish English Neuropsychological Assessment Scale in older adult Latines and those at risk for autosomal dominant Alzheimer's disease. 西班牙-英语神经心理评估量表在老年拉丁人和常染色体显性阿尔茨海默病高危人群中的应用
IF 2.2 4区 心理学
Journal of clinical and experimental neuropsychology Pub Date : 2023-08-01 Epub Date: 2023-12-29 DOI: 10.1080/13803395.2023.2284971
Kayla N Tureson, Christopher R Beam, Luis D Medina, Freddi Segal-Gidan, Lina M D'Orazio, Helena Chui, Mina Torres, Rohit Varma, John M Ringman
{"title":"Use of the Spanish English Neuropsychological Assessment Scale in older adult Latines and those at risk for autosomal dominant Alzheimer's disease.","authors":"Kayla N Tureson, Christopher R Beam, Luis D Medina, Freddi Segal-Gidan, Lina M D'Orazio, Helena Chui, Mina Torres, Rohit Varma, John M Ringman","doi":"10.1080/13803395.2023.2284971","DOIUrl":"10.1080/13803395.2023.2284971","url":null,"abstract":"<p><strong>Objective: </strong>The Spanish English Neuropsychological Assessment Scale (SENAS) is a cognitive battery with English and Spanish versions for use with persons for whom either language is predominant. Few studies have examined its utility outside the normative sample. The current study examined SENAS performance in samples of older adult Latines and Latines with or at risk for autosomal dominant Alzheimer's disease (ADAD) mutations.</p><p><strong>Method: </strong>The SENAS was administered to 202 older adults from the Los Angeles Latino Eye Study (LALES) and 29 adults with (carriers) or without (non-carriers) mutations causing ADAD. We examined associations between SENAS, age, education, and language (LALES) and between SENAS, estimated years from familial age of dementia diagnosis, education, language, and acculturation (ADAD). Partial correlations were used to examine differences in correlational strength between estimated years from familial age of dementia diagnosis and SENAS scores among ADAD carriers compared to chronological age and SENAS in the LALES sample. Exploratory t-tests were performed to examine SENAS performance differences between ADAD carriers and non-carriers.</p><p><strong>Results: </strong>In an older adult sample (LALES), increased age correlated with worse verbal delayed recall; English fluency and higher education correlated with better naming and visuospatial subtest performance. Among ADAD carriers, verbal and nonverbal delayed recall and object naming subtest performance worsened as they approached their familial age of dementia diagnosis. English fluency and higher U.S.-acculturation were related to better SENAS performance among carriers and non-carriers. Tests of verbal delayed recall and object naming best distinguished ADAD carriers from their familial non-carrier counterparts.</p><p><strong>Conclusions: </strong>Verbal delayed recall and object naming measures appear to be most sensitive to age-related changes in older adult samples and mutation-related changes in distinguishing ADAD carriers from non-carriers. Future research should examine the sensitivity of SENAS in other samples, such as larger samples of symptomatic ADAD carriers and other AD subtypes.</p>","PeriodicalId":15382,"journal":{"name":"Journal of clinical and experimental neuropsychology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10926998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138291073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visuoconstructional impairment in DM1: exploring underlying cognitive processes through the Rey complex figure. DM1视觉结构损伤:通过Rey复杂图形探索潜在的认知过程。
IF 2.2 4区 心理学
Journal of clinical and experimental neuropsychology Pub Date : 2023-08-01 Epub Date: 2023-12-29 DOI: 10.1080/13803395.2023.2274623
Joana Garmendia, Andone Sistiaga, Garazi Labayru
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