Journal of Neuropsychology最新文献

Dopamine genetic risk scores and psychiatric symptoms: Interacting risk factors for impulse control behaviours in de novo Parkinson's disease.

IF 2 4区心理学

Journal of Neuropsychology Pub Date : 2025-01-28 DOI: 10.1111/jnp.12415

Emma Whooley, Vincent Koppelmans, Hayley J MacDonald, Alison Hall, Marit F L Ruitenberg

{"title":"Dopamine genetic risk scores and psychiatric symptoms: Interacting risk factors for impulse control behaviours in de novo Parkinson's disease.","authors":"Emma Whooley, Vincent Koppelmans, Hayley J MacDonald, Alison Hall, Marit F L Ruitenberg","doi":"10.1111/jnp.12415","DOIUrl":"10.1111/jnp.12415","url":null,"abstract":"Up to 45% of patients with Parkinson's disease (PD) experience impulse control disorders (ICDs), characterized by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development of ICDs in PD. A total of 278 de novo PD patients (ICD-free at enrollment) were selected from the Parkinson's Progression Markers Initiative database. ICD presence at baseline and yearly follow-up assessments were evaluated via the Questionnaire for Impulsive-Compulsive Disorders. Symptoms of anxiety and depression at baseline were measured via the State-Trait-Anxiety Inventory and Geriatric Depression Scale, respectively. Furthermore, an individual dopamine genetic risk score was calculated according to polymorphisms in genes coding for dopamine (D1, D2 and D3 receptors and catechol-O-methyltransferase), with higher scores reflecting higher central dopamine neurotransmission. In total, 146 participants (47.5%) developed an ICD with an average onset time of 36 months (range 3-96) from baseline. Results from a Cox proportional hazards model showed a trait anxiety × genetics interaction, suggesting that individuals with both higher baseline trait anxiety scores and higher dopamine genetic risk scores were at increased risk of ICD development. This interaction remained significant after controlling for age, sex and motor symptom severity. Our findings suggest that genetic and psychiatric predictors of impulsivity in PD interact and jointly yield increased ICD risk during the course of the disorder. This implies that early screening of anxiety symptoms in combination with genotyping can be useful to identify those at risk for ICD.","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reimagining André Rey's method for recording the copy process of the Rey Complex Figure Test: A commentary.

IF 2 4区心理学

Journal of Neuropsychology Pub Date : 2025-01-24 DOI: 10.1111/jnp.12414

Maneesh V Kuruvilla, Angela Blazely

{"title":"Reimagining André Rey's method for recording the copy process of the Rey Complex Figure Test: A commentary.","authors":"Maneesh V Kuruvilla, Angela Blazely","doi":"10.1111/jnp.12414","DOIUrl":"https://doi.org/10.1111/jnp.12414","url":null,"abstract":"In 1941, André Rey published the Rey Complex Figure, a widely used test for assessing visual-constructional ability and visual memory. It consists of two parts: copy and recall. Evaluating the copy portion presents challenges, as it requires the administrator to focus on both the process and outcome. The assessor must systematically track how the patient copies the figure in real-time to evaluate their planning, organisation and executive abilities. This 'clinician's copy' serves as a record of the patient's approach, aiding later judgements about their cognitive skills. To ensure accuracy, clinicians need a method to record this process for later review or colleague consultation. This paper revisits Rey's suggestion of using different coloured pencils to observe the copy sequence, proposing an alternative. Instead of providing coloured pencils to the patient, we recommend that the administrator use them to record the copy sequence. This method aligns with test norms, reducing potential distractions for the patient while enabling both experienced and novice administrators to easily track and document the sequence of copying.","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143031804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Time to align sensitive cognitive assessment with protein biomarkers in Alzheimer's disease. 是时候将阿尔茨海默病的敏感认知评估与蛋白质生物标志物结合起来了。

IF 2 4区心理学

Journal of Neuropsychology Pub Date : 2025-01-19 DOI: 10.1111/jnp.12413

Jet M J Vonk

引用次数: 0

Comparison of children and adolescents diagnosed with attention deficit hyperactivity disorder with and without autism traits in terms of emotion regulation, clinical characteristics and functionality. 儿童青少年注意缺陷多动障碍伴与不伴自闭症特征的情绪调节、临床特征和功能比较

IF 2 4区心理学

Journal of Neuropsychology Pub Date : 2025-01-08 DOI: 10.1111/jnp.12411

Buket Kılıç, Sadriye E Ç Kültür

{"title":"Comparison of children and adolescents diagnosed with attention deficit hyperactivity disorder with and without autism traits in terms of emotion regulation, clinical characteristics and functionality.","authors":"Buket Kılıç, Sadriye E Ç Kültür","doi":"10.1111/jnp.12411","DOIUrl":"https://doi.org/10.1111/jnp.12411","url":null,"abstract":"This study aims to demonstrate that children and adolescents diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) who exhibit autism traits have a more severe clinical profile in terms of emotion regulation, clinical features related to ADHD, and functionality, compared to those diagnosed with ADHD without these traits. 50 patients with and 64 patients without autism traits between the ages of 8-16 were recruited for the study among the children and adolescents diagnosed with ADHD. The Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version, DSM-5-2016-Turkish Adaptation (K-SADS-PL-DSM-5-T) was used to exclude the diagnosis of Autism Spectrum Disorder (ASD) and detect comorbid psychiatric diagnosis. The Social Reciprocity Scale (SRS) was completed by parents to determine groups based on autism traits. Children completed the Childhood Anxiety Sensitivity Index (CASI) and the Affective Reactivity Index (ARI). The Strengths and Difficulties Questionnaire (SDQ), Affective Reactivity Index-Parent Report (ARI-P) and Weiss Functional Impairment Rating Scale-Parent Report (WFIRS-P) were completed by the parents. We found that the group with autism traits had significantly more hyperactivity/inattention, conduct problems, emotional problems, and peer problems and significantly more irritability and frequent separation anxiety disorder. Although there was no significant impairment in functionality in either group, the level of impairment was significantly higher in the group with autism traits. Children diagnosed with Attention Deficit Hyperactivity Disorder who exhibit autism traits experience higher levels of irritability and separation anxiety disorder, as well as greater impairment in functionality, compared to those without these traits.","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are patients with Parkinson's disease impaired in the recognition of emotion's authenticity? 帕金森氏症患者对情绪真实性的认知是否受损？

IF 2 4区心理学

Journal of Neuropsychology Pub Date : 2024-12-26 DOI: 10.1111/jnp.12410

Agnese Anzani, Stefano Zago, Teresa Difonzo, Cristina Scarpazza, Nadia Bolognini, Giulia Franco, Alessio Difonzo, Maria Cristina Saetti

{"title":"Are patients with Parkinson's disease impaired in the recognition of emotion's authenticity?","authors":"Agnese Anzani, Stefano Zago, Teresa Difonzo, Cristina Scarpazza, Nadia Bolognini, Giulia Franco, Alessio Difonzo, Maria Cristina Saetti","doi":"10.1111/jnp.12410","DOIUrl":"https://doi.org/10.1111/jnp.12410","url":null,"abstract":"In recognising emotions expressed by others, one can make use of both embodied cognition and mechanisms that do not necessarily require activation of the limbic system, such as evoking from memory the meaning of morphological features of the observed face. Instead, we believe that the recognition of the authenticity of an emotional expression is primarily based on embodied cognition, for which the mirror system would play a significant role. To verify this hypothesis, we submitted 20 parkinsonian patients and 20 healthy control subjects to the Emotional Authenticity Recognition test, a novel test using dynamic stimuli to evaluate the ability to recognise emotions and their authenticity. Analysis of variance of the test scores shows that Parkinsonian patients perform worse than controls when they had to recognise the authenticity of emotions, although they are able to identify them. Our results confirm a deficit in the recognition of the authenticity of emotions in patients with Parkinson's disease attributable to the disruption of extrapiramidal limbic circuit between ventral striatum and orbitomesial-prefrontal cortex.","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multifactorial interplay on language recovery following left-hemispheric stroke: A retrospective study. 多因素相互作用对左半球中风后语言恢复的影响：一项回顾性研究。

IF 2 4区心理学

Journal of Neuropsychology Pub Date : 2024-12-23 DOI: 10.1111/jnp.12406

Célise Haldin, Shenhao Dai, Céline Piscicelli, Valérie Marcon, Hélène Lœvenbruck, Dominic Pérennou, Monica Baciu

{"title":"Multifactorial interplay on language recovery following left-hemispheric stroke: A retrospective study.","authors":"Célise Haldin, Shenhao Dai, Céline Piscicelli, Valérie Marcon, Hélène Lœvenbruck, Dominic Pérennou, Monica Baciu","doi":"10.1111/jnp.12406","DOIUrl":"https://doi.org/10.1111/jnp.12406","url":null,"abstract":"Understanding the relative contribution of various factors influencing initial severity of aphasia and recovery after a stroke is essential for optimising neurorehabilitation programmes. We investigated how various significant sociodemographic, cognitive, clinical, stroke-related and rehabilitation-related factors modulate aphasia severity and language recovery following left-hemispheric stroke. Employing an innovative method, we conducted a retrospective analysis of 96 stroke participants to explore the combined impact of these factors. The initial severity of aphasia was categorised into severe, mild/moderate and no aphasia based on the severity of their language deficits in the subacute phase (Aphasia Severity Rating Scale, ASRS). To assess speech-and-language recovery, we classified 53/96 patients with aphasia into high and poor recovery categories using a gain score formula (ASRS_discharge-ASRS_admission)/ASRS_admission. Subsequently, we performed statistical analyses (univariate analyses and forward stepwise logistic regression combined with bootstrap) to identify the determinants of the initial severity of aphasia and the degree of recovery. Our analyses unveiled that more severe aphasia initially was correlated with a more severe stroke (Odds Ratio, OR = .90, p = .041), moderate/severe executive dysfunction (OR = .068, p < .001) and larger lesion size (OR = .068, p < .001). Furthermore, the degree of recovery was associated with the intensity of speech-and-language therapy (OR = 1.47, p = .043). These findings enrich our understanding of the determinants of aphasia severity and language recovery, employing an original methodology to scrutinise the collective effect of multiple variables in a retrospective analysis of stroke participants. A better knowledge of these factors may help implement personalised language rehabilitation programmes to maximise speech-and-language recovery.","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early neuropsychological screening and long-term functional outcome in a sample of patients affected by mild stroke: The ReSCog Project. 轻度中风患者样本的早期神经心理学筛查和长期功能结局：ReSCog项目

IF 2 4区心理学

Journal of Neuropsychology Pub Date : 2024-12-22 DOI: 10.1111/jnp.12408

Elisa Pini, Fulvio Pepe, Veronica Laini, Nicoletta Ciccarelli, Eugenio Magni

{"title":"Early neuropsychological screening and long-term functional outcome in a sample of patients affected by mild stroke: The ReSCog Project.","authors":"Elisa Pini, Fulvio Pepe, Veronica Laini, Nicoletta Ciccarelli, Eugenio Magni","doi":"10.1111/jnp.12408","DOIUrl":"https://doi.org/10.1111/jnp.12408","url":null,"abstract":"Stroke causes severe long-term disabilities with a significant reduction in quality of life. This study aims to explore the predictive value of cognitive screening in the acute phase of mild stroke on patients' functional outcome after discharge. A total of 110 patients with mild stroke were recruited. Patients were included in the study if they were discharged directly home from the acute units. The cognitive profile of patients was assessed with the Oxford Cognitive Screen (OCS). The OCS was administered 3-10 days after stroke, providing a five domain-specific cognitive profile. Long-term functional outcomes were evaluated by the Stroke Impact Scale 3.0 (SIS 3.0), a self-reported questionnaire that includes physical, cognitive, emotional and social participation dimensions. All patients completed the survey online on average 10 months after stroke. Our results show that OCS is positively associated with physical and cognitive dimensions, after adjusting for age and stroke severity measured by NIHSS at admission. In conclusion, OCS in acute mild stroke seems to be an independent predictor of long-term functional outcomes and could help clinicians in the long-term management of patients.","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can machine learning assist us in the classification of older patients suffering from dementia based on classic neuropsychological tests and a new financial capacity test performance? 机器学习能否根据经典的神经心理学测试和一项新的财务能力测试表现，帮助我们对老年痴呆症患者进行分类？

IF 2 4区心理学

Journal of Neuropsychology Pub Date : 2024-12-18 DOI: 10.1111/jnp.12409

Vaitsa Giannouli, Stylianos Kampakis

{"title":"Can machine learning assist us in the classification of older patients suffering from dementia based on classic neuropsychological tests and a new financial capacity test performance?","authors":"Vaitsa Giannouli, Stylianos Kampakis","doi":"10.1111/jnp.12409","DOIUrl":"https://doi.org/10.1111/jnp.12409","url":null,"abstract":"Aims: Predicting the diagnosis of an older adult solely based on their financial capacity performance or other neuropsychological test performance is still an open question. The aim of this study is to highlight which tests are of importance in diagnostic protocols by using recent advancements in machine learning.Methods: For this reason, a neuropsychological battery was administered in 543 older Greek patients already diagnosed with different types of neurocognitive disorders along with a test specifically measuring financial capacity, that is, Legal Capacity for Property Law Transactions Assessment Scale (LCPLTAS). The battery was analysed using a random forest algorithm. The objective was to predict whether an older person suffers from dementia. The algorithm's performance was tested through cross-validation.Results: Machine learning was applied for the first time in data analysis regarding financial capacity and three factors-tests were revealed as the best predictors: two subscales from the LCPLTAS measuring 'financial decision making' and 'cash transactions', and the widely used MMSE which measures general cognition. The algorithm demonstrated good performance as measured by the F1-score, which is a measure of the harmonic mean of precision and recall. This evaluation metric in binary and multi-class classification integrates precision and recall into a single metric to gain a better understanding of model performance.Conclusions: These findings reveal the importance of focusing on these scales and tests in neuropsychological assessment protocols. Future research may clarify in other cultural settings if the same variables are of importance.","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decision-making using the Iowa gambling test in unaffected first-degree relatives of obsessive-compulsive disorder: Comparison with healthy controls and patients with obsessive-compulsive disorder. 在未受影响的强迫症一级亲属中使用爱荷华赌博测试的决策：与健康对照和强迫症患者的比较。

IF 2 4区心理学

Journal of Neuropsychology Pub Date : 2024-12-17 DOI: 10.1111/jnp.12407

Keitaro Murayama, Hirofumi Tomiyama, Aikana Ohono, Kenta Kato, Akira Matsuo, Mingi Kang, Tomohiro Nakao

引用次数: 0

IF 2 4区心理学

Journal of Neuropsychology Pub Date : 2024-12-16 DOI: 10.1111/jnp.12405

Logan A Gaudet, Lena Rybka, Emmanuel Mandonnet, Emmanuelle Volle, Marion Barberis, Roel Jonkers, Adrià Rofes

{"title":"Leveraging relatedness-based measures in people with language disorders: A scoping review.","authors":"Logan A Gaudet, Lena Rybka, Emmanuel Mandonnet, Emmanuelle Volle, Marion Barberis, Roel Jonkers, Adrià Rofes","doi":"10.1111/jnp.12405","DOIUrl":"https://doi.org/10.1111/jnp.12405","url":null,"abstract":"Understanding lexico-semantic processing is crucial for dissecting the complexities of language and its disorders. Relatedness-based measures, or those which investigate the degree of relatedness in meaning between either task items or items produced by participants, offer the opportunity to harness novel computational and analytical techniques from cognitive network science. Recognizing the need to deepen our understanding of lexico-semantic deficits through diverse experimental and analytical approaches, this review explores the use of such measures in research into language disorders. A comprehensive search of four electronic databases covering publications from the last 11 years (October 2013-September 2024) identified 38 original experimental studies employing relatedness-based measures in populations with language disorders or other neurological conditions. Articles were examined for the types of tasks used, populations studied, item selection methods and analytical approaches. The predominant use of category fluency tasks emerged across studies, with a notable absence of relatedness judgement tasks or comparable paradigms. Commonly discussed populations included individuals with post-stroke aphasia, mild cognitive impairment and schizophrenia. Analytical methods varied significantly, ranging from more traditional approaches of clustering and switching to more sophisticated computational techniques. Despite the evident utility of category fluency tasks in research and clinical settings, the review underscores a critical need to diversify experimental paradigms and probe lexico-semantic processing in a more multifaceted manner. A broadened approach in future language disorder research should incorporate innovative analytical techniques, investigations of neural correlates and a wider array of tasks employing relatedness-based measures already present in healthy populations.","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0