Case Reports in Nephrology and Dialysis最新文献_第2页

Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage - A Case Series Analysis. 揭露风险隐患：中药所致肾损害-个案系列分析。

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Case Reports in Nephrology and Dialysis Pub Date : 2025-03-21 eCollection Date: 2025-01-01 DOI: 10.1159/000545186

Ashok Bhat, Rohan Desai, Mahesha Vankalakunti

{"title":"Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage - A Case Series Analysis.","authors":"Ashok Bhat, Rohan Desai, Mahesha Vankalakunti","doi":"10.1159/000545186","DOIUrl":"https://doi.org/10.1159/000545186","url":null,"abstract":"Introduction: Herbal medications have been utilized for centuries to treat various ailments, yet their potential to induce renal damage is often underestimated. The popularity of herbal remedies, especially in rural India, stems from cultural beliefs in their holistic healing properties.Case presentations: This case series comprises 4 patients exhibiting varied renal presentations linked to herbal medication usage. Notably, oxalate nephropathy emerged as a predominant finding. Through comprehensive clinical assessments and renal biopsies, we elucidated the pathophysiological mechanisms underlying herbal nephrotoxicity. Timely recognition and discontinuation of the offending herb, alongside tailored therapeutic interventions like corticosteroid administration, facilitated favourable patient outcomes.Conclusion: These cases underscore the importance of considering herbal remedies as potential culprits in renal dysfunction, particularly in regions where their usage is prevalent. Our findings emphasize the imperative for healthcare practitioners to proactively inquire about herbal medication use in patients with renal failure. Heightened awareness and further research into the safety and mechanisms of herbal nephrotoxicity are essential for optimizing patient care and preventing herb-induced kidney injury.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"15 1","pages":"60-69"},"PeriodicalIF":0.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12021384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Visual Loss and Mesenteric Nodules: Two Case Reports of Atypical Presentations of Calciphylaxis. 急性视力丧失和肠系膜结节：2例钙化反应的不典型表现。

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Case Reports in Nephrology and Dialysis Pub Date : 2025-03-17 eCollection Date: 2025-01-01 DOI: 10.1159/000545309

Wu Tzen Lim, Rajiv Juneja, Rachel Yi Ping Tan

{"title":"Acute Visual Loss and Mesenteric Nodules: Two Case Reports of Atypical Presentations of Calciphylaxis.","authors":"Wu Tzen Lim, Rajiv Juneja, Rachel Yi Ping Tan","doi":"10.1159/000545309","DOIUrl":"https://doi.org/10.1159/000545309","url":null,"abstract":"Introduction: Calciphylaxis is a systemic disease that predominantly affects individuals with chronic kidney disease, particularly in the advanced stages. It is a potentially life-threatening condition with significant morbidity. The exact underlying mechanisms leading to calciphylaxis are not fully understood. Cutaneous manifestations are the typical presentation of calciphylaxis, where patients develop painful skin ulcers affecting their extremities. However, calciphylaxis involving visceral organs are rare.Case presentations: We present 2 cases where the initial clinical picture of calciphylaxis was atypical. The first case is a haemodialysis patient presenting with unilateral acute vision loss, mimicking giant cell arteritis. The second case is a failed transplant graft recipient on peritoneal dialysis with incidental radiological findings of heavily calcified mesenteric nodules.Conclusion: These cases highlight the importance of a high clinical suspicion of calciphylaxis as it can masquerade other clinical conditions.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"15 1","pages":"70-77"},"PeriodicalIF":0.7,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemodialysis Treatment for High-Dose Quetiapine Fumarate Poisoning: A Case Report. 高剂量富马酸奎硫平中毒的血液透析治疗1例。

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Case Reports in Nephrology and Dialysis Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1159/000545048

Jiaoyang Li, Zhiqin Chen, Shuran Qian, Xuemei Liu

{"title":"Hemodialysis Treatment for High-Dose Quetiapine Fumarate Poisoning: A Case Report.","authors":"Jiaoyang Li, Zhiqin Chen, Shuran Qian, Xuemei Liu","doi":"10.1159/000545048","DOIUrl":"https://doi.org/10.1159/000545048","url":null,"abstract":"Introduction: Quetiapine is a new atypical antipsychotic with minor side effects. There have been few reports of rhabdomyolysis and acute kidney injury associated with quetiapine overdose.Case presentation: This article presents a rare case of high-dose quetiapine poisoning that improved after treatment. The patient experienced rhabdomyolysis, acute kidney injury, long QT syndrome, and peripheral neuropathy, all of which are typical complications of quetiapine poisoning. Moreover, a kidney biopsy verified the patient's acute tubulointerstitial injury, and immunohistochemical staining demonstrated that myoglobin cast nephropathy was the cause of the injury. This patient's kidney function and associated complications recovered after receiving hemodialysis, rehabilitation, heart rate regulation, and further symptomatic interventions. Consequently, hemodialysis was discontinued.Conclusion: Our case showed that myoglobin cast nephropathy was the cause of the acute kidney injury associated with quetiapine poisoning. The kidney biopsy is essential for accurate diagnosis and treatment.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"15 1","pages":"41-46"},"PeriodicalIF":0.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Collaborative Management of Hyperkalemia in Patients with Complex Heart Failure. 复杂心力衰竭患者高钾血症的协同管理。

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Case Reports in Nephrology and Dialysis Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1159/000543931

Ellie Kelepouris, Nihar Desai, Katherine A A Clark, Mikhail N Kosiborod, Jeffrey Budden, Sandra Waechter, Michael Böhm

{"title":"Collaborative Management of Hyperkalemia in Patients with Complex Heart Failure.","authors":"Ellie Kelepouris, Nihar Desai, Katherine A A Clark, Mikhail N Kosiborod, Jeffrey Budden, Sandra Waechter, Michael Böhm","doi":"10.1159/000543931","DOIUrl":"https://doi.org/10.1159/000543931","url":null,"abstract":"Introduction: The aim of this study was to highlight the benefits and provide a framework for integrated multispecialty team involvement in the management of hyperkalemia in patients with heart failure (HF) and kidney disease and to ensure that patients receive optimal medical therapy to improve their clinical outcomes.Case presentation: This report highlights a hypothetical \"complex\" case of a patient with an acute HF decompensation who experiences hyperkalemia following up-titration of renin-angiotensin-aldosterone system inhibitor (RAASi) therapy. Two hypothetical scenarios for treatment management are discussed; in the first, providers down-titrate guideline-directed RAASi to avoid hyperkalemia, whereas in the second, providers take a collaborative interdisciplinary approach to manage hyperkalemia directly with the aim of avoiding RAASi down-titration. In the first typical management scenario, down-titration of guideline-directed RAASi to prevent increases in serum potassium (serum K+) levels leads to the reoccurrence of symptoms and rehospitalization of the patient. In the second proposed management scenario, interdisciplinary team discussions around differing tolerances and approaches to raised serum K+ levels lead to maintenance of guideline-directed RAASi doses with the help of close monitoring of the patient, introduction of a low potassium diet, and prescription of potassium binder therapy.Conclusion: Collaborative multispecialty team management of HF patients may enable successful management of hyperkalemia without the need for discontinuation of guideline-directed RAASi therapy. Collaboration could extend to regular virtual or face-to-face cardiorenal clinics, where complex cases can be discussed, and local guidelines and processes can be developed.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"15 1","pages":"47-52"},"PeriodicalIF":0.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11999659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cyclosporine A Combined with Rituximab Successfully Treated Erythropoietin-Induced Pure Red Blood Cell Aplastic Anemia. 环孢素A联合利妥昔单抗成功治疗促红细胞生成素诱导的纯红细胞再生障碍性贫血。

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Case Reports in Nephrology and Dialysis Pub Date : 2025-03-04 eCollection Date: 2025-01-01 DOI: 10.1159/000543844

Honghui Zeng, Hong He, Xintian Shi, Ying Wang, Xin Wei

{"title":"Cyclosporine A Combined with Rituximab Successfully Treated Erythropoietin-Induced Pure Red Blood Cell Aplastic Anemia.","authors":"Honghui Zeng, Hong He, Xintian Shi, Ying Wang, Xin Wei","doi":"10.1159/000543844","DOIUrl":"https://doi.org/10.1159/000543844","url":null,"abstract":"Introduction: Erythropoietin-induced pure red blood cell aplastic anemia (EPO-PRCA) is a rare anemia, which presents a significant treatment challenge, often necessitating the cessation of erythropoiesis-stimulating agents and the adoption of immunosuppressive therapies or renal transplantation.Case presentation: In the present case, the patient developed severe anemia after 2-year EPO treatment and was diagnosed with EPO-PRCA. The treatment with the full dose of corticosteroids and testosterone for 1 month failed to increase his hemoglobin level significantly. Therefore, the patient received the combination therapy of cyclosporine A (CsA) with rituximab, which effectively cleared the anti-EPO antibody. Then, roxadustat was given to improve renal anemia. As Hb level increased gradually, the patient was recovered from EPO-PRCA.Conclusion: This case reported an EPO-PRCA patient was successfully cured by the combination of CsA with rituximab and provided another choice for the treatment of EPO-PRCA in the future.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"15 1","pages":"53-59"},"PeriodicalIF":0.7,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12021380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Constrictive Pericarditis in a Hemodialysis Patient Who Presented with Rapidly Progressive Pericardial Calcification: A Diagnostic Challenge - A Case Report. 缩窄性心包炎在血液透析患者表现为快速进展心包钙化：一个诊断挑战-一个病例报告。

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Case Reports in Nephrology and Dialysis Pub Date : 2025-02-11 eCollection Date: 2025-01-01 DOI: 10.1159/000543999

Oho Tsunematsu, Shin-Ichi Takeda, Mitsutaka Yamaguchi, Miwa Kaneko, Kazuho Oe, Yoshiaki Murakami, Daisuke Nagata

{"title":"Constrictive Pericarditis in a Hemodialysis Patient Who Presented with Rapidly Progressive Pericardial Calcification: A Diagnostic Challenge - A Case Report.","authors":"Oho Tsunematsu, Shin-Ichi Takeda, Mitsutaka Yamaguchi, Miwa Kaneko, Kazuho Oe, Yoshiaki Murakami, Daisuke Nagata","doi":"10.1159/000543999","DOIUrl":"https://doi.org/10.1159/000543999","url":null,"abstract":"Introduction: Constrictive pericarditis (CP) is characterized by impaired diastolic filling of the ventricles, which typically causes right heart failure. Its diagnosis may be challenging because it mimics other disorders. Furthermore, prompt diagnosis and treatment are more crucial in cases of hemodialysis; otherwise, maintenance dialysis would be hampered by severe hypotension.Case presentation: We report the case of a 53-year-old man on hemodialysis who developed CP with shock. His blood pressure was 55/30 mm Hg at the time of hospitalization due to presyncope. He continued hemodialysis but with some difficulty. However, right pleural effusion persisted because of impaired fluid removal by hemodialysis. Despite such severe manifestations, the distinctive clinical features of CP were lacking. By carefully evaluating the time course of computed tomography images, progressive calcification in the pericardium emerged as a significant clue. Cardiac catheterization subsequently revealed a dip-and-plateau pattern of right ventricular pressure, which led to a definitive diagnosis of CP. Soon after the diagnosis, he underwent successful surgery.Conclusion: An important finding was that, unlike calcific lesions in the general dialysis population, the patient's calcific lesions were mostly confined to the pericardium and progressed on a monthly basis. Thus, the present case may provide deep insight into the diagnosis of CP and the management of hemodialysis patients with severe hypotension.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"15 1","pages":"33-40"},"PeriodicalIF":0.7,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11908808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Manual Dilution of Continuous Renal Replacement Therapy Fluids in Anuric Patients with Severe Hyponatremia: A Case Report and Systematic Review. 手工稀释持续肾替代治疗液治疗无尿严重低钠血症患者：一例报告和系统评价。

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Case Reports in Nephrology and Dialysis Pub Date : 2025-01-29 eCollection Date: 2025-01-01 DOI: 10.1159/000543718

Mark V Koning, Lassima Reijnen, Femy Kemperman, Eugenie Schipper-Reintjes

{"title":"Manual Dilution of Continuous Renal Replacement Therapy Fluids in Anuric Patients with Severe Hyponatremia: A Case Report and Systematic Review.","authors":"Mark V Koning, Lassima Reijnen, Femy Kemperman, Eugenie Schipper-Reintjes","doi":"10.1159/000543718","DOIUrl":"https://doi.org/10.1159/000543718","url":null,"abstract":"Introduction: When a patient with severe hyponatremia requires renal replacement therapy, a too rapid correction of sodium levels may occur. Manual dilution of the fluids during continuous renal replacement therapy (CRRT) is a method that can lead to a controlled correction of sodium. We present a case and add a systematic review to determine the feasibility of this method.Case presentation: A female was admitted to the intensive care unit with acute kidney failure due to anti-glomerular basement membrane antibody glomerulonephritis, anuria, and an initial sodium level of 100 mmol/L. She received CRRT with manually diluted fluids for 6 days, in which sodium levels increased from 108 mmol/L to 130 mmol/L. A search in Medline, Web of Science, and Google Scholar was added for the systematic review. The search yielded 49 cases, including the current report, of which 47 were anuric or oliguric, in which the fluids were diluted to a median of 8 mmol/L (interquartile range 5-11) (range 0-17) above the serum sodium, the median CRRT dose was 27 mL/kg/h (22-30) (13-77.5). This led to an increase in serum sodium of 0.2 mmol/L/h (0.1-0.3) (0-0.7).Conclusion: CRRT with manually diluted fluids in patients with severe hyponatremia and anuria can lead to a controlled increase serum sodium, while allowing sufficient RRT dose and fluid removal. Still, errors in dilution may occur and we recommend 4 hourly monitoring of serum sodium levels to timely detect an inadvertent increase in sodium.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"15 1","pages":"26-32"},"PeriodicalIF":0.7,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11857161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Forearm's Subcutaneous Venous Network to Accelerate Maturation of Native Arteriovenous Fistula: A Case Report. 前臂皮下静脉网络加速原生动静脉瘘成熟：1例报告。

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Case Reports in Nephrology and Dialysis Pub Date : 2024-12-21 eCollection Date: 2025-01-01 DOI: 10.1159/000542903

Maciej Gołębiowski, Mariia Chumadevska, Mariusz Kusztal, Mirosław Banasik, Tomasz Gołębiowski

{"title":"The Forearm's Subcutaneous Venous Network to Accelerate Maturation of Native Arteriovenous Fistula: A Case Report.","authors":"Maciej Gołębiowski, Mariia Chumadevska, Mariusz Kusztal, Mirosław Banasik, Tomasz Gołębiowski","doi":"10.1159/000542903","DOIUrl":"10.1159/000542903","url":null,"abstract":"Introduction: A common complication of arteriovenous fistula (AVF) is thrombosis in the venous segment, which can impair vascular access unless a successful thrombectomy is performed.Case presentation: In this manuscript, we describe the case of a diabetic patient who had primary AVF in a snuff-box with subsequent superficialization of the medial vein of the forearm. Unfortunately, this section of the vein was occluded, although the fistula was patent through the cephalic vein (CV). Due to insufficient flow, this vascular access was unsuitable for hemodialysis. Using a vein from the subcutaneous venous network (SVN), additional AVF was performed. Our goal was to accelerate maturation by doubling arteriovenous flow, which then increased the size of the CV in the arm. After maturation, a second superficialization was performed on the arm, which allowed for successful cannulation.Conclusion: SNV may be considered for the creation of a new AVF to improve the maturation of the primary fistula.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"15 1","pages":"9-14"},"PeriodicalIF":0.7,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of Pediatric Colchicine Poisoning with Single-Pass Albumin Dialysis: A Case Report. 单次白蛋白透析治疗小儿秋水仙碱中毒1例。

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Case Reports in Nephrology and Dialysis Pub Date : 2024-12-11 eCollection Date: 2025-01-01 DOI: 10.1159/000543020

Atessa Bahadori, Rishil Patel, Cal Robinson, Steve Balgobin, Michael Zappitelli, Nithiakishna Selvathesan

{"title":"Treatment of Pediatric Colchicine Poisoning with Single-Pass Albumin Dialysis: A Case Report.","authors":"Atessa Bahadori, Rishil Patel, Cal Robinson, Steve Balgobin, Michael Zappitelli, Nithiakishna Selvathesan","doi":"10.1159/000543020","DOIUrl":"10.1159/000543020","url":null,"abstract":"Introduction: Colchicine has a narrow therapeutic index, and doses >0.5 mg/kg are considered toxic with a high mortality rate.Case presentation: A previously healthy 15-year-old presents to the emergency department with abdominal pain and vomiting following intentional ingestion of colchicine (0.56 mg/kg) 12 h prior. By 24 h post-ingestion, they developed a multi-organ injury with hepatic dysfunction, coagulopathy, lactic acidemia, and pancytopenia, which prompted consideration of extracorporeal therapy (ECT). Considering the characteristics of colchicine, they were treated with continuous venovenous hemodiafiltration (CVVHDF) with single-pass albumin dialysis (SPAD) for 42 h. They were subsequently discharged from the intensive care unit 48 h after stopping CVVHDF with normal kidney function, resolved coagulopathy, and resolving pancytopenia and hepatic dysfunction. The rationale for CVVHDF with SPAD was based on the high protein binding, variably high volume of distribution, previous reports showing a sieving coefficient of 0.2 with CVVH, and the high mortality risk. We anticipated a high potential for rebound. Thus, continuous clearance would facilitate redistribution from the extravascular to intravascular space. SPAD was used to enhance the elimination of protein-bound fractions; the principle is that adding albumin to dialysate creates a protein-binding disequilibrium where the drug from the blood side may bind to albumin on the dialysate side.Conclusion: Colchicine ingestion of >0.5 mg/kg is highly toxic, and in addition to supportive management, continuous kidney replacement therapy with SPAD may be considered.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"15 1","pages":"1-8"},"PeriodicalIF":0.7,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling a Rarity: First Instance of Urinary Tract Infection Caused by Corynebacterium tuberculostearicum in India. 揭示罕见：第一例尿路感染由结核棒状杆菌引起的硬脂质在印度。

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Case Reports in Nephrology and Dialysis Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.1159/000542203

Aditya Kundu, Nirmalya Ghosh, Mallika Sengupta, Shiv Sekhar Chatterjee

{"title":"Unveiling a Rarity: First Instance of Urinary Tract Infection Caused by Corynebacterium tuberculostearicum in India.","authors":"Aditya Kundu, Nirmalya Ghosh, Mallika Sengupta, Shiv Sekhar Chatterjee","doi":"10.1159/000542203","DOIUrl":"10.1159/000542203","url":null,"abstract":"Introduction: Corynebacterium species other than C. diphtheriae are being continuously reported as pathogens.Case presentation: A patient visited the Urology Outpatient Department of a tertiary care centre in India reporting lower abdominal pain, urinary incontinence, and intermittent weak urine flow persisting for 12 years, intensifying over the last 15 days. She also experienced urgency, straining, weak stream, and incomplete voiding, along with a previous fever episode. The patient had a medical record of multiple urethral dilations and surgeries since 2014, with the most recent urethral dilatation in July 2023. Diagnostic tests revealed a thickened bladder with notable post-void residual urine. Uroflowmetry indicated obstructive uropathy. Urine analysis exhibited elevated leucocytes, epithelial cells, red blood cells, and abundant bacilli. Corynebacterium tuberculostearicum was identified through matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) following three pure growths of Gram-positive bacilli in urine cultures. The organism showed sensitivity to cotrimoxazole and tetracyclines. Treatment with doxycycline significantly improved the symptoms.Conclusion: The organism Corynebacterium tuberculostearicum is a very rare cause of UTI and the patient responded well to treatment.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"14 1","pages":"185-189"},"PeriodicalIF":0.7,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11614444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0