Nigerian medical journal : journal of the Nigeria Medical Association最新文献

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Spontaneous subgaleal haematoma with severe headache in two children during acute painful sickle cell crisis. 急性疼痛镰状细胞危像期间自发性无骨下血肿伴严重头痛二例。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.71480/nmj.v66i1.615
Francis Akor, Toby Thenat, Sajjad Hussain, Suresh Kumar
{"title":"Spontaneous subgaleal haematoma with severe headache in two children during acute painful sickle cell crisis.","authors":"Francis Akor, Toby Thenat, Sajjad Hussain, Suresh Kumar","doi":"10.71480/nmj.v66i1.615","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.615","url":null,"abstract":"<p><p>Sickle cell disease is an inherited disorder of haemoglobin formation, predominantly affecting individuals of African, Indian, or Mediterranean descent. Acute painful episodes frequently occur in these patients due to the blockage of small blood vessels by sickled cells, leading to tissue infarction. Two children of Nigerian descent, presented with severe headaches during a painful crisis episode with associated swelling on their scalps. CT imaging in both cases showed subgaleal haematoma which was managed conservatively in addition to managing the painful crisis with a good outcome. This report highlights the clinical presentation, diagnostic approach, and management of this uncommon complication of sickle cell anaemia.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"379-384"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Call to Action: Insights into Hypertension Prevalence and Management in an Urban Sub-Saharan African Population. 行动呼吁:对撒哈拉以南非洲城市人口高血压患病率和管理的见解。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.71480/nmj.v66i1.712
Teko Blaise Mbah, Bernadette Sandrine Lema, Armand Boris Rikam, Jacques Merci Baning Baning, Serge's Bruno Ngon, Georgette Merveille Kilama, Divine GoufanA Ngon, Odile Israelle Meto A Ngon, Fabrice Peguy Thome Ebango, Suzanne Adolphine Soppi Ebango, Emmanuel Eroume A Egom
{"title":"A Call to Action: Insights into Hypertension Prevalence and Management in an Urban Sub-Saharan African Population.","authors":"Teko Blaise Mbah, Bernadette Sandrine Lema, Armand Boris Rikam, Jacques Merci Baning Baning, Serge's Bruno Ngon, Georgette Merveille Kilama, Divine GoufanA Ngon, Odile Israelle Meto A Ngon, Fabrice Peguy Thome Ebango, Suzanne Adolphine Soppi Ebango, Emmanuel Eroume A Egom","doi":"10.71480/nmj.v66i1.712","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.712","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a global health challenge, with a disproportionate burden in low- and middle-income countries like Cameroon. Urban centers, such as Yaoundé, face increasing prevalence driven by rapid urbanization and healthcare disparities. The study objective is to assess hypertension prevalence, associated risk factors, and barriers to effective management in an urban Cameroonian population.</p><p><strong>Methodology: </strong>A cross-sectional study was conducted in 2024 as part of the HEAVEN-CIEL Hypertension Awareness Campaign. Data from 181 adults were collected through structured questionnaires and physical assessments, including blood pressure measurements. Associations with demographic, socioeconomic, and lifestyle factors were analyzed using chi-square tests and logistic regression.</p><p><strong>Results: </strong>Hypertension prevalence was 59.67%, with rates peaking at 75.56% among individuals aged 46-60 years (p = 0.0019). Medium-income participants showed the highest prevalence at 75.56% (p = 0.043). Obesity (p = 0.0024) and high-fat diets (p = 0.0212) were significant risk factors. Alarmingly, 87.04% of hypertensive individuals were untreated, highlighting gaps in medication access and adherence.</p><p><strong>Conclusion: </strong>Hypertension in Yaoundé represents a major public health concern, driven by age, socioeconomic disparities, and unhealthy lifestyle factors. The low treatment rates reflect systemic healthcare barriers. Comprehensive, culturally sensitive interventions are urgently needed to improve awareness, prevention, and management. Future research should focus on the longitudinal impacts of targeted public health strategies.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"290-302"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emotional and Behavioural Problems of HIV-infected Children: Findings from a Southeastern Nigeria Tertiary Healthcare Facility. 感染艾滋病毒儿童的情绪和行为问题:来自尼日利亚东南部三级医疗机构的调查结果。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.71480/nmj.v66i1.639
Ikechukwu Frank Ogbonna, Nwaonu Chijioke Nwakanma, Joseph Ezeogu, Kelechi Kenneth Odinaka
{"title":"Emotional and Behavioural Problems of HIV-infected Children: Findings from a Southeastern Nigeria Tertiary Healthcare Facility.","authors":"Ikechukwu Frank Ogbonna, Nwaonu Chijioke Nwakanma, Joseph Ezeogu, Kelechi Kenneth Odinaka","doi":"10.71480/nmj.v66i1.639","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.639","url":null,"abstract":"<p><strong>Background: </strong>In children, HIV infection presents with grave consequences, including a predisposition to emotional and behavioural problems (EBP). These are mental health problems affecting thoughts, emotions, behaviours and relationships, and may be categorised into emotional problems (EP) and behavioural problems (BP). Studies have shown a high burden of EBP in children; however, knowledge gaps still exist regarding the burden of EBP on HIV-infected children. Our study seeks to address these gaps by determining the prevalence and type of EBP among HIV-infected children.</p><p><strong>Methodology: </strong>This cross-sectional and comparative study enrolled 386 participants (193 subjects and 193 controls). The subjects were HIV-infected children aged 2-15 years attending the Paediatric HIV Clinic of Federal Medical Centre, Umuahia. The controls were age and sex-matched HIV-negative children attending primary or secondary schools in Umuahia. Sociodemographic characteristics were assessed, and EBP was determined using the strengths and difficulties questionnaire.</p><p><strong>Results: </strong>Sixty-one subjects (31.6%) had EBP compared to 15 controls (7.8%) and this difference was significant (<i>p</i><0.001). The subjects were three times more likely to have EBP than the controls (aOR=3.03; CI=1.17-7.82). The EBP type showed that, while there was no significant difference in the multivariate analysis of the behavioural problems, emotional problems were significantly higher in the subjects than in the controls (<i>p</i> = 0.001). The subjects were six times more likely to have emotional problems than the controls (aOR=6.26; CI=2.80-13.97).</p><p><strong>Conclusion: </strong>There is a high burden of EBP among HIV-infected children in Umuahia with emotional problems as the common type.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"117-126"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
B-Mode Ultrasound Grading of Cryptogenic Steatotic Liver Disease and Association with the Level of Sun Exposure in Zaria, Nigeria: A Case-Control Study. 尼日利亚Zaria地区隐源性脂肪变性肝病的b超分级及其与阳光照射水平的关系:一项病例对照研究
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.71480/nmj-v66i1.723
Philip Oluleke Ibinaiye, Benjamin Egbo, Adebanke Olarinoye-Akorede, Bako Joseph Igashi, Tokan Silas Baduku, Bello Omuya Usman, Manko Muhammad, Abdurrahman El-Fulaty Ahmad, Musa Abdulkadir Tabari, Mustapha Kagu Shettima, Muhammed Shakir Balogun, Mohammed Kabir Saleh
{"title":"B-Mode Ultrasound Grading of Cryptogenic Steatotic Liver Disease and Association with the Level of Sun Exposure in Zaria, Nigeria: A Case-Control Study.","authors":"Philip Oluleke Ibinaiye, Benjamin Egbo, Adebanke Olarinoye-Akorede, Bako Joseph Igashi, Tokan Silas Baduku, Bello Omuya Usman, Manko Muhammad, Abdurrahman El-Fulaty Ahmad, Musa Abdulkadir Tabari, Mustapha Kagu Shettima, Muhammed Shakir Balogun, Mohammed Kabir Saleh","doi":"10.71480/nmj-v66i1.723","DOIUrl":"https://doi.org/10.71480/nmj-v66i1.723","url":null,"abstract":"<p><strong>Background: </strong>Cryptogenic Steatotic Liver Disease (CSLD) is a novel subject where the liver has significant steatosis but without a known cause or abnormal cardiometabolic risk factors. Its aetiology and associations with sunlight exposure remain underexplored, particularly in Nigeria. CSLD is a growing public health concern in Nigeria, characterized by its potential progression to severe liver complications such as cirrhosis and liver cancer, posing significant health risks. This study aimed to determine the association between CSLD and the level of sun exposure.</p><p><strong>Methodology: </strong>This case-control study involved 181 healthy subjects with CSLD and an equal number of normal subjects without CSLD as controls. This made for a total number of 362 subjects. They were recruited into the study consecutively as they emerged after clinical, laboratory, and imaging screenings. A liver ultrasound scan was done using a 3.5MHz frequency transducer to screen for the steatotic liver. The severity of liver steatosis was evaluated by ultrasound bright liver scores (BLS). A daily sun exposure score based on our local pattern was calculated using the information from the administered questionnaire. The data were analyzed with GraphPad Prism software version 6.</p><p><strong>Results: </strong>the median (IQR) age of CSLD and control groups were 44.0 (28.5 - 54.0) and 44.0 (30.0 - 55.0) years. Wilcoxon matched pairs signed rank comparison test showed no significant difference in the ages of the two study groups (<i>p</i> = 0.5578), indicating age matching of the study participants. There was a significant association (χ<sup>2</sup> = 59.03, df = 18, <i>p</i>< 0.0001) between age and development of CSLD. One hundred and eighty-one study subjects with CSLD comprised 83 (45.8%) males and 98 (54.1%) females.The median (IQR) values of the control group's sun exposure score differed significantly from those of the CSLD groups (<i>p</i> = 0.0001) for all categories (mild, moderate, severe steatosis). A multivariate logistic regression analysis model, weighted by years of age and sex, revealed that low sunlight exposure is a significant independent risk factor.</p><p><strong>Conclusion: </strong>The study shows that limited sun exposure is significantly associated with developing CSLD among Nigerians in Zaria. There is also a significant independent risk factor.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"319-326"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between Maternal Diseases and Placental Morphology among Parturient's in Port Harcourt, River State: A Multi-Centre Study. 河州哈科特港产妇疾病与胎盘形态的关系:一项多中心研究
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.71480/nmj.v66i1.571
Alerechi Emeka-Ogbugo, Simeon Chijioke Amadi, Jane Dumle Gbobie, Abbey Mkpe, Paul Ledee Kua, Ada Nkemagu Okocha, Oluwagbemiga Adewale
{"title":"Relationship between Maternal Diseases and Placental Morphology among Parturient's in Port Harcourt, River State: A Multi-Centre Study.","authors":"Alerechi Emeka-Ogbugo, Simeon Chijioke Amadi, Jane Dumle Gbobie, Abbey Mkpe, Paul Ledee Kua, Ada Nkemagu Okocha, Oluwagbemiga Adewale","doi":"10.71480/nmj.v66i1.571","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.571","url":null,"abstract":"<p><strong>Background: </strong>Maternal diseases that complicate pregnancies such as Pregnancy induced hypertension (PIH) or Gestational Diabetes Mellitus (GDM) etc are markedly impressed on the placenta microscopically and macroscopically resulting in in defective placental development and perinatal morbidity and mortality. This study aimed to study the gross anatomy of the placenta and its relationship with maternal medical illnesses.</p><p><strong>Methodology: </strong>This study was a multi-centre hospital-based prospective cross-sectional study of 250 parturient who had term deliveries in Port Harcourt. The socio-demographic data and the medical history of the parturient were collected using a proforma. The placenta was collected after delivery and examined, and the morphometric features were noted. Data analysis was done with SPSS IBM version 23. Correlation and Regression analysis were employed in investigating the relationship between maternal/neonatal characteristics and placental morphology. Statistical significance was at a p-level of less than 0.05.</p><p><strong>Results: </strong>The mean age of the women ± SD = 30.44±4.1years and the median parity was para-2. Gestational Hypertension was the most common medical condition among participants. There was a statistically significant association between the maternal medical conditions and the placental shape with a preponderance of the oval shape among the women with hypertensive disorders. There was also, a statistically significant association between maternal medical conditions in pregnancy and other placental measurements such as weight, number of cotyledons, diameter, thickness, and cord insertion.</p><p><strong>Conclusion: </strong>Maternal medical conditions in pregnancy was found to have significant macroscopic imprints on the placental morphology and these can help in the diagnosis and management of medical illnesses that complicate pregnancies in our environment. More research is needed to establish causation.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"70-81"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Gut-Microbiome and mental health and effects of probiotics on psychiatric disorders: A Meta-analysis and systematic review. 肠道微生物组与心理健康的关系以及益生菌对精神疾病的影响:荟萃分析和系统综述。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.71480/nmj.v66i1.601
Ramita Goel, Bhupesh Gupta, Vimal Naranbhai Satodiya, Ashok Ukabhai Vala, Hetal Dabhi, Anshu Mittal
{"title":"Association of Gut-Microbiome and mental health and effects of probiotics on psychiatric disorders: A Meta-analysis and systematic review.","authors":"Ramita Goel, Bhupesh Gupta, Vimal Naranbhai Satodiya, Ashok Ukabhai Vala, Hetal Dabhi, Anshu Mittal","doi":"10.71480/nmj.v66i1.601","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.601","url":null,"abstract":"<p><strong>Background: </strong>A correlation between gut microbiome and mental health has drawn significant attention lately. The effects of microbiome microorganisms and their byproducts on disease states represent a complex and dynamic field of study. The objective of this article is to review the association of gut microbes and mental health and the effects of probiotics on psychiatric disorders, if any.</p><p><strong>Methodology: </strong>This meta-analysis was conducted using the PRISMA standards. We have compiled the most recent advancements in the field according to human research published in this Systematic review and meta-analysis.</p><p><strong>Results: </strong>The forest plot analysis revealed that probiotics or probiotics combined with other intervention modalities did significantly reduce some extent of mental disorders in comparison to the control group (Standardized mean difference) SMD = 0.95, 95% Confidence Interval (CI): -6.52 to 8.42, P value< 0.01.</p><p><strong>Conclusion: </strong>Overall, the reviewed literature supports the importance of gut microbiota-brain interaction in human mental illnesses, including the impact of probiotics on mental health outcomes and brain connection.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"13-25"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and diagnostic dilemma of chromosomal abnormalities in the Niger Delta area of Nigeria; Is prenatal diagnosis worthwhile? 尼日利亚尼日尔三角洲地区染色体异常的患病率及诊断困境产前诊断值得吗?
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.71480/nmj.v66i1.561
Mkpe Abbey, Boma Awoala West, Simeon Chijioke Amadi, Olufemi Adebari Oloyede, Faithwin Horsfall, Esther Ijeoma Nonye-Enyidah, Kenneth Eghuan Okagua, Ngozi Joseph Kwosah, Paul Ledee Kua, Rose Sitonma Iwo-Amah, Uduak Solomon Ocheche, Chidiebere Nwakanma Ononuju, Nimi Ngo Briggs, Basil Omiebi Altraide, Leesi Sapira-Ordu, Nestor Inimgba
{"title":"Prevalence and diagnostic dilemma of chromosomal abnormalities in the Niger Delta area of Nigeria; Is prenatal diagnosis worthwhile?","authors":"Mkpe Abbey, Boma Awoala West, Simeon Chijioke Amadi, Olufemi Adebari Oloyede, Faithwin Horsfall, Esther Ijeoma Nonye-Enyidah, Kenneth Eghuan Okagua, Ngozi Joseph Kwosah, Paul Ledee Kua, Rose Sitonma Iwo-Amah, Uduak Solomon Ocheche, Chidiebere Nwakanma Ononuju, Nimi Ngo Briggs, Basil Omiebi Altraide, Leesi Sapira-Ordu, Nestor Inimgba","doi":"10.71480/nmj.v66i1.561","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.561","url":null,"abstract":"<p><strong>Background: </strong>Early detection of increasing numbers of cases of chromosomal abnormalities (aneuploides) at the Rivers State University Teaching Hospital (RSUTH) in the Niger Delta will enhance appropriate counseling of patients and early termination of the affected pregnancies. The study aimed to ascertain the prevalence of aneuploides at the RSUTH and to determine the necessity for early prenatal diagnosis in the Niger Delta.</p><p><strong>Methodology: </strong>This was a prospective cross-sectional study carried out over a three-year period (01/01/2018 - 01/01/2021) at the RSUTH, Nigeria. Newborn babies delivered at 28 weeks and above were assessed at birth for the phenotypes of aneuploidy and associated birth defects. A convenient sampling method was used to recruit all the babies with chromosomal abnormalities and their mothers. Data including that of socio-demographic, obstetric characteristics, and the fetuses were taken and analyzed using Statistical Package for Social Sciences Version 23 (SPSS version 23). Quantitative variables were summarized using means and standard deviation while qualitative variables were expressed as frequencies and proportions.</p><p><strong>Results: </strong>The total number of babies that were delivered by the 5868 participants in the study was 6078, out of which 10 cases of aneuploides were identified - 3 cases of trisomy 18 and 7 cases of Trisomy 21. The prevalence of chromosomal abnormalities at birth at the RSUTH was 0.165% of the total births, 1:2000 and 1:654 for T18 and T21 respectively. 1:654 mothers had babies with chromosomal abnormalities, 1:2000 and 1:833 for T18 and T21 respectively.Conclusion: The prevalence of chromosomal abnormalities at birth at the RSUTH of 0.165% represented a gross underestimation because the diagnosis was based on the outward phenotypical appearance of the neonates and it was made not from babies delivered at 20 weeks and above as practiced in Europe and other countries, but from 28 weeks. Prenatal diagnosis was therefore highly recommended in the Niger Delta.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"60-69"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiation proctitis as a differential of lower GIT bleeding in Nigeria: A case series. 放射性直肠炎作为尼日利亚下GIT出血的鉴别诊断:一个病例系列。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.71480/nmj.v66i1.556
Evaristus Sunday Chukwudike, Nyam Paul David, Emmanuel Obasi, John John Ogan, Chinenye Unoma Nwoko, Chinwe Philomena Onyia, Kenechukwu Chukwuemeka Okonkwo, Lukman Olaitan Abdulkareem, Winnifred Njideka Adiri, Stella-Maris Chinma Egbo, Egbo Oziegbe, Pantong Mark Davwar
{"title":"Radiation proctitis as a differential of lower GIT bleeding in Nigeria: A case series.","authors":"Evaristus Sunday Chukwudike, Nyam Paul David, Emmanuel Obasi, John John Ogan, Chinenye Unoma Nwoko, Chinwe Philomena Onyia, Kenechukwu Chukwuemeka Okonkwo, Lukman Olaitan Abdulkareem, Winnifred Njideka Adiri, Stella-Maris Chinma Egbo, Egbo Oziegbe, Pantong Mark Davwar","doi":"10.71480/nmj.v66i1.556","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.556","url":null,"abstract":"<p><p>Pelvic radiotherapy is an acceptable and promising treatment modality for various pelvic malignancies. However, it is associated with radiation-induced injury on surrounding structures with a preference for the rectum, which is characteristically fixed in the pelvic region. Acute radiation proctitis is usually self-limiting, but in its chronic form, it can be debilitating. Recent advances in radiation therapy have significantly reduced the prevalence of radiation proctitis (RP) in high-income countries, contrary to the findings in low and middle-income countries witnessing an increasing burden of radiation proctitis. This observation can be attributed to the increased availability of radiation therapies with limited use of novel technologies designed to reduce the detrimental effects of radiotherapy and improve the detection of RP owing to improvements in endoscopic services in developing countries. This is a highlight of the trends in the presentation of RP, management modalities in various tertiary centers in Nigeria, and the limitations in care occasioned by the non-availability of argon plasma coagulation (APC) as an effective treatment modality in most tertiary health facilities in Nigeria.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"370-378"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Prevalent Hypertension by Aortic versus Brachial Blood Pressure Criteria for - A Pulse Wave Analysis Based Study from Adults of a City of West India. 基于脉搏波分析的西印度某城市成人主动脉和肱动脉血压标准对高血压的比较
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.71480/nmj.v66i1.616
Jayesh D Solanki, Pearl K Sajan, Bansi J Trivedi, Param J Kakadia, Sunil J Panjwani, Krishnapriya Mohandas
{"title":"Comparison of Prevalent Hypertension by Aortic versus Brachial Blood Pressure Criteria for - A Pulse Wave Analysis Based Study from Adults of a City of West India.","authors":"Jayesh D Solanki, Pearl K Sajan, Bansi J Trivedi, Param J Kakadia, Sunil J Panjwani, Krishnapriya Mohandas","doi":"10.71480/nmj.v66i1.616","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.616","url":null,"abstract":"<p><strong>Background: </strong>Disparities exist in aortic blood pressure (aBP) and brachial blood pressure (bBP) and between aortic (AH) versus brachial hypertension (BH). While the former is superior, it is studied scarcely. Pulse wave analysis (PWA) provides objective and simultaneous measurement of both blood pressures to determine AH and BH. Using PWA, we compared prevalent AH and BH in a sample adult population.</p><p><strong>Methodology: </strong>By oscillometric PWA (Mobilograph, IEM, Stolberg, Germany), 1187 participants with age >18 years were evaluated. Simultaneous aBP and bBP were recorded by standard PWA protocol and prevalence of AH and BH was estimated. Age and gender-based subgroups were compared for aortic versus brachial BP differences. Prevalence of Hypertension, Isolated Systolic Hypertension, and Pulse Pressure ≥40 was compared between aortic versus brachial criteria.</p><p><strong>Results: </strong>Significant differences were seen between bBP and aBP across all age groups and in both genders, especially for the younger age groups. As compared to bBP, aBP gave a higher fetch for prevalent hypertension and a lower fetch for prevalent Isolated Systolic Hypertension (ISH). bPP ≥40 was sensitive but not specific as a surrogate for aPP ≥ 40.</p><p><strong>Conclusion: </strong>Across ages 18-65 in either sex, disparities exist between bBP and aBP mostly for SBP and PP with significant differences in prevalent Hypertension, Isolated Systemic Hypertension, and high pulse pressure. It reaffirms disparities of aBP and bBP and diagnosed brachial or central hypertension based on them with the need for further work.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"109-116"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Mid-Palatal Suture Maturation Stage in Adolescents and Adults Using Cone Beam Computed Tomography (CBCT)- A Comparative Study. 锥形束计算机断层扫描(CBCT)评价青少年和成人中腭缝合成熟阶段的比较研究。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.71480/nmj.v66i1.744
Ravinder Singh, Deepak Gupta, Aashna Garg, Veenu Dahiya, Paras Gupta, Ramandeep Singh Gambhir
{"title":"Evaluation of Mid-Palatal Suture Maturation Stage in Adolescents and Adults Using Cone Beam Computed Tomography (CBCT)- A Comparative Study.","authors":"Ravinder Singh, Deepak Gupta, Aashna Garg, Veenu Dahiya, Paras Gupta, Ramandeep Singh Gambhir","doi":"10.71480/nmj.v66i1.744","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.744","url":null,"abstract":"<p><strong>Background: </strong>Several methods have been described in orthodontics for the evaluation of the skeletal age. These include hand-wrist radiography and cervical vertebral maturation (CVM) based on lateral cephalogram. Computed tomography (CT) scan has emerged as an effective tool for image diagnosis in situ. The present study was done to assess the stages of the mid-palatal suture in adolescents and adults utilizing cone beam computed tomography (CBCT).</p><p><strong>Methodology: </strong>A descriptive and prospective study was done on 110 CBCT scans of individuals aged between 10-30 years, who visited the Department of Oral Medicine and Radiology, MMCDSR, Ambala, Haryana. The visualization and classification of the stage of maturation of the mid-palatine suture was done as per Angelieri's method using a cross-sectional axial slice.</p><p><strong>Results: </strong>Stage C was found to be the most prevalent (29.1%) with the majority of cases occurring in the 16-20 age range. Males were more likely to have Stage B, while females had Stage C. In 60 cases (54.5 percent of the overall sample), the mid-palatine suture was found to be open. The Chi-Square test results for each examiner were highly significant (p< 0.01), indicating a statistically significant association between age group and Stage distribution.</p><p><strong>Conclusion: </strong>There is a higher chance that post-adolescents and adults will have an open mid-palatal suture. When maxillary expansion is necessary, orthodontists may take these consequences into account. Furthermore, the middle palatal suture's ossification varies, hence using CBCT to rule out this possibility may be advised.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"347-356"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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