Nigerian medical journal : journal of the Nigeria Medical Association最新文献

{"title":"Ovarian Cancers in a Northern Nigerian Hospital: Epidemiology, Clinicopathology and Treatment Options.","authors":"Akwaowo Etukudo, Aisha Mustapha, Zainab Ali Adamu, Shehu Salihu Umar, Yusuf Tukur, Anisah Yahya, Murtala Abubakar, Adekunle Olanrewaju Oguntayo, Bala Mohammed Audu","doi":"10.71480/nmj.v66i1.604","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.604","url":null,"abstract":"<p><strong>Background: </strong>In Nigeria, Ovarian cancer is the most lethal gynaecologic cancer. The management of disease in developing countries poses a huge challenge due to late presentation and/or diagnosis, poverty, poor health insurance coverage, and the dearth of specialists in the region amongst others. Record keeping is poor. Treatment options are limited with high default rates and mortality. This was a five-year review of clinicopathology and treatment strategies for ovarian cancers in Ahmadu Bello University Teaching Hospital, Zaria.</p><p><strong>Methodology: </strong>A retrospective study of all primary ovarian cancers diagnosed and or treated in ABUTH Zaria from 1st January 2016 to 31st December 2020 was carried out. A total of 38 cases were retrieved and relevant data was extracted. The data collected were entered into Open Data Kit (ODK) and analysed using descriptive statistics.</p><p><strong>Results: </strong>Most patients were aged 35 to 54 years with an overall mean age of 51.2 ±13.8 years. Only 34% of patients were nulliparous and 63.2% were post-menopausal. The commonest symptoms were abdominal swelling (94.7%), and abdominal pain (68.4%). Epithelial carcinomas (81.8%) were the commonest histotype of which serous adenocarcinoma (85.1%) was the commonest. There was no distinction between high-grade and low-grade serous carcinomas. Rare ovarian tumours (germ cell and sex cord/stromal) accounted for 18.2%. Most patients presented with stage III disease and above (77.7%) with no one presenting at stage I. Thirty-five patients (92.1%) had surgery, twenty-four (63.2%) had chemotherapy and four patients (10.5%) had targeted therapy. No patient had hormonal therapy, genetic testing, Poly-adenosine diphosphate-ribose polymerase inhibitors (PARPi), Hyperthermic intraperitoneal chemotherapy (HIPEC), or palliative radiotherapy. Only 12% had an MDT discussion. One-year post-diagnosis, the majority were lost to follow-up (73.7%) while 21.1% of patients were still on follow-up.</p><p><strong>Conclusion: </strong>Ovarian cancer patients in ABUTH were relatively younger, unemployed, multiparous, and symptomatic. Some standards of care management practices were omitted.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"99-108"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep disturbances in Healthcare Workers During the COVID-19 Pandemic.","authors":"Abdelkrim Khannous, Samira Essoli, Adraa Khannous, Fatiha Bounoua, Oussama Halloumi, Houda Moubachir, Latifa Adarmouch, Hind Serhane","doi":"10.71480/nmj.v66i1.573","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.573","url":null,"abstract":"<p><strong>Background: </strong>Many studies have reported the negative impact of the COVID-19 pandemic on the rhythms and sleep in various populations. Particularly in frontline healthcare workers, which are highly susceptible to developing sleep disturbances. Therefore, the present study was conducted to determine the prevalence and determinants of sleep disturbances in healthcare workers at the regional Hospital Hassan II in Agadir, Morocco.</p><p><strong>Methodology: </strong>A cross-sectional study among frontline healthcare workers was conducted at the Regional Hospital in Agadir, by administering an online questionnaire using the Google Forms platform distributed through social media. The questionnaire was anonymous, and data confidentiality was assured. Data analysis was performed using SPSS version 21.</p><p><strong>Results: </strong>A total of 54 healthcare professionals filled in the questionnaire. The mean age was 28.81±05.35, The two-thirds were female participants (59.3%), and the mean Epworth score was 07.53±04.05, High prevalence rates of sleep disorders were reported as follows; sleep onset insomnia (27.4), excessive daytime sleepiness (24.1), snoring (24.1).We found that morning headaches and concentration difficulties are factors associated with sleep disorders among healthcare workers.</p><p><strong>Conclusion: </strong>COVID-19 has a high risk of poor sleep quality, with many consequences. Measures to improve the sleep and well-being of healthcare workers are needed.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"82-90"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Pattern of Analgesic Abuse Among Undergraduate Students of University of Port Harcourt, Rivers State, Nigeria.","authors":"Fredrick C Enuagwuna, Charles I Tobin-West, Favour A Dappa, Thank-God C Bethel","doi":"10.71480/nmj.v66i1.647","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.647","url":null,"abstract":"<p><strong>Background: </strong>The habitual or excessive use of painkillers, including prescription and over-the-counter drugs, that deviates from medical guidelines is known as analgesic abuse, and this includes taking larger doses than recommended, using the drugs for non-medical purposes, or continuing to take the medication despite adverse effects on one's physical, mental, and social well-being. Devastating health effects may result from this. The prevalence and patterns of analgesic abuse among University of Port Harcourt undergraduate students were evaluated in this study.</p><p><strong>Methodology: </strong>A descriptive cross-sectional study was conducted, and respondents were selected using a multistage sampling method. A self-administered, structured questionnaire was used to gather the data, and IBM Statistical Product for Service Solution (SPSS) version 25 was used to analyze the data; means, frequency, proportions, chi-square, and regression analysis were used to summarize the results. A p-value of less than 0.05 was deemed statistically significant.</p><p><strong>Results: </strong>384 students in all, with a median age of 20, were interviewed. The distribution of results showed that 207 (53.9%) of the respondents were males and 177 (46.1%) were females. The majority of responders, 339 (69.6%), used paracetamol, with headaches accounting for 316 (57.4%) of all uses. The findings also showed that the prevalence of analgesic abuse was 9.1%, with paracetamol being the most frequently abused medicine (42.9%).</p><p><strong>Conclusion: </strong>Although the results indicated that the prevalence of analgesic abuse among University of Port Harcourt undergraduate students was low, most respondents used analgesic medication without a prescription from a doctor. The most common reasons for using analgesics were headaches, muscle pain, and menstrual cramps. It is crucial that the institution implements strategic plans to ensure that students are taught how to use analgesics properly.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"142-155"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mandibular reconstruction with non-vascularized bone graft in a double bridging technique.","authors":"Obitade Sunday Obimakinde, Sunday Ogunsuyi Popoola, Kehinde Olubukola Ojo, Moruf Babatunde Yusuf, John Adetunji Omotayo, Akinwale Olaleye Akinbade","doi":"10.71480/nmj.v66i1.581","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.581","url":null,"abstract":"<p><strong>Background: </strong>Reconstruction of the mandible following tumor resection or trauma can be challenging due to associated functional and esthetic problems. Various options have been described in the literature, but non-vascularized bone graft remain a viable option in middle- and low-income countries, Nigeria inclusive. We hereby report our experience with the use of non-vascularized bone graft with mandibular reconstruction plates in a double bridging technique for mandibular reconstruction in our institution.</p><p><strong>Methodology: </strong>Patients who had mandibular defect reconstruction with non-vascularized bone graft between January 2012 and December 2021 were included in this study. Grafts were harvested from either the rib or contralateral iliac crest and secured with mandibular reconstruction plate and screws in a double bridging technique. Patients were followed for a minimum of 12 months and outcomes such as the level of patients' satisfaction with appearance, graft take, bony continuity and complications were assessed and analyzed.</p><p><strong>Results: </strong>Twenty eight patients comprising 18 males and 10 females [M:F 1.8:1] had mandibular defect reconstruction with double bridging technique during the study period. Donor site distribution revealed that 64.3% [n=18] had their grafts harvested from the iliac crest while the remaining 10 [35.7%] were taken from the rib. Ameloblastoma [75%, n=21] was the commonest lesion necessitating resection of the mandible amongst the subjects. The follow up result showed that appearance was satisfactory in 25 patients [89%], graft take/ restoration of bony continuity in 27 patients [96%], graft infection occurred in 2 patients [7.1%] while only one case of graft failure was established [3.6%].</p><p><strong>Conclusion: </strong>A combination of non-vascularized bone graft with reconstruction plate in a bridging technique is a viable option for mandibular reconstruction in a resource-limited setting.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"91-98"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Verification of the HbA1c method on the STANDARD F2400^® analyzer in a Nigerian Laboratory.","authors":"Modupe Akinrele Kuti, Jokotade Oluremilekun Adeleye","doi":"10.71480/nmj.v66i1.698","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.698","url":null,"abstract":"<p><strong>Background: </strong>For methods that report quantitatively, an assessment of their imprecision and bias should be assessed in the laboratory before their deployment into routine service. This study assessed these parameters of the HbA1C method on the STANDARD F2400® point of care analyzer. These parameters were further combined to generate sigma metrics for the method.</p><p><strong>Methodology: </strong>An external quality assurance (EQA) material from the Randox International Quality Assessment Scheme (RIQAS) was analysed according to the EP15 protocol of the Clinical Laboratory Standards Institute in SYNLAB Nigeria Laboratory Quality Assurance Department. Estimates of precision and an assessment of bias were determined from the data which consisted of 5 replicates per day for 5 consecutive days. Precision estimates were compared with manufacturer-provided information and estimates of bias were compared with the verification interval for the target value provided by RIQAS. Sigma metrics were determined for total allowable error (TAE) of 8% and 10%.</p><p><strong>Results: </strong>The grand mean (standard deviation) for the study was 4.95 (0.15) %. The Within-run CV and within laboratory CV were 1.28% and 1.86%, respectively. These were within the manufacturer claims of 1.70% and 1.90%, also respectively. The target value by RIQAS was 5.04(0.24) % with a calculated verification interval of 4.95 - 5.13%. The sigma metrics for the method at TAE of 8% and 10% were 4.8/3.3 and 6.3/4.3 within the run/within laboratory estimates respectively.</p><p><strong>Conclusion: </strong>The HbA1C method on the STANDARD F2400® Analyzer displayed performance characteristics that are consistent with manufacturer specifications and are above industry standard quality for a point-of-care device for HbA1C. These suggest that may be used to support routine monitoring of persons with diabetes mellitus in Nigeria.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"246-255"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perception of Enrollee Health Insurance Fraud among Healthcare Workers at a Tertiary Hospital in Kaduna State, North-western Nigeria.","authors":"Hajara Adamu Kasim, Auwal Garba Suleiman, Fahad Abubakar Saulawa, Suleiman Usman, Muhammad Aliyu, Nazifi Sani Aminu","doi":"10.71480/nmj.v66i1.700","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.700","url":null,"abstract":"<p><strong>Background: </strong>Fraud in healthcare is an immense challenge that poses a direct threat to sustainable healthcare financing across low and high-income countries. Enrollee health insurance fraud is a relatively understudied form of fraud that thrives in settings characterized by weak and fragmented healthcare systems. This study examined the knowledge and perception of enrollee health insurance fraud among healthcare workers at a tertiary hospital in Kaduna State, North-western Nigeria.</p><p><strong>Methodology: </strong>Using a stratified sampling technique, 232 healthcare workers were interviewed using a structured, self-administered questionnaire that was developed for the study. Data on knowledge and perception of enrollee fraud was obtained and analysed using IBM SPSS Statistics. The data was presented using frequency distribution tables, while figures were drawn using Microsoft Excel.</p><p><strong>Results: </strong>The majority of the respondents were clinical staff, including medical doctors (29.7%), nurses (31.5%) and health assistants (14.2%). A total of170 (73.3%) respondents were aware of enrollee fraud and up to 113 (66.5%) encountered at least one case of enrollee fraud. The most common types of enrollee fraud identified by the respondents were impersonation (67.7%) and faking symptoms (57.1%). Respondents recognised adverse consequences of enrollee fraud, including depletion of resources (74.1%), blocking eligible patients from accessing care (73.6%), and exhaustion of healthcare workers (61.8%). A total of 111 (65.3%) agreed that enrollee fraud is common in the hospital and despite a high level of awareness, only 72 (42.3%) agreed that they are adequately informed about enrollee fraud.</p><p><strong>Conclusion: </strong>There was a high level of awareness of enrollee fraud among the respondents with a good perception of its manifestations and implications on healthcare delivery. It is recommended that immediate steps be taken to educate healthcare workers and enhance their capacity to detect and deter enrollee fraud while investing in longterm strategic measures and technology-based solutions.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"256-265"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of Uptake of Routine Immunization amongst Under-Five Children: Comparison of Nomadic and Non-nomadic Fulani in Yobe State, Nigeria.","authors":"Dauda Abdulhamid, Usman Muhammad Ibrahim, Boateng Kofi, Sunday Audu, Mahdi Musa Wade, Abba Ahmed Danzomo, Nuruddeen Muhammad, Abdullahi Namadi Faruk, Salihu Abdullahi Ahmed, Jamilu Aliyu Bawa, Abdullahi Sadiq Uba, Tukur Ismail, Awwal Umar Gajida, Abubakar Mohammed Jibo","doi":"10.71480/nmj.v66i1.542","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.542","url":null,"abstract":"<p><strong>Background: </strong>Immunization is an important public health intervention that reduces morbidity and mortality associated with vaccine-preventable diseases (VPDs). This study aimed to determine and compare the correlates of routine immunization uptake among under-five children of nomadic and non-nomadic Fulani in Yobe State, Nigeria.</p><p><strong>Methodology: </strong>A multistage sampling technique was used to study the eligible caregivers and under-five children in the selected households using an interviewer-administered questionnaire, observation for the child immunization card, or a recall of immunization history. Data were analysed using IBM SPSS version 22.0 with a statistical significance set at p≤5%.</p><p><strong>Results: </strong>The response rate among nomadic and non-nomadic Fulani was (348/348, 100% vs. 345/348, 99%).The Penta 1 uptake based on routine immunization cards among nomadic and non-nomadic under-five children was (23.6% vs.76.4% P<0.001).Availability of the vaccine (adjusted odds ratio = 22, 95% confidence interval = 13.7-35.5), the purpose of vaccination (adjusted odds ratio = 1.9, 95% confidence interval = 1.1-3.4), vaccines safety (adjusted odds ratio = 17.3, 95% confidence interval = 10.0-29.8), and friendly healthcare workers (adjusted odds ratio = 18.8, 95% confidence interval = 11.3-31.3) were found to be independent predictors facilitating uptake of routine immunization among nomadic and non-nomadic under-five children, while long distance to the health facility (adjusted odds ratio = 9.6, 95% confidence interval = 6.6-14.0), lack of knowledge on immunization (adjusted odds ratio = 2.1, 95% confidence interval = 1.4-2.9), fear of side effect (adjusted odds ratio = 1.6, 95% confidence interval = 1.1-2.5), were independent barriers to uptake of routine immunization among nomad and non-nomadic under-five children.</p><p><strong>Conclusion: </strong>Vaccine uptake is still a problem among nomads and non-nomadic under-five children. The government and relevant stakeholders should ensure a strategy for improved outreach services to all the nomads and hard-to-reach settlements.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"44-59"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Optic Atrophy and Epiretinal Membranes: An Atypical Presentation of Ocular Tuberculosis.","authors":"Yewande Olubunmi Babalola","doi":"10.71480/nmj.v66i1.711","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.711","url":null,"abstract":"<p><p>A 15-year-old boy presented himself to the retina clinic with a six-year history of poor vision in both eyes. Ocular symptoms started with deterioration in the vision of both eyes associated with ocular pain. There was no history of antecedent trauma, headaches, seizures, or loss of consciousness. The general and systemic examinations were normal. On ocular examination, the corrected visual acuity was 6/24 and 6/6 in the right and left eyes, respectively. The anterior segment examination was normal except for a relative afferent pupillary defect in the right eye. Examination of the posterior segment revealed bilateral optic atrophy worse in the right eye and cup disc ratios of 0.3 bilaterally. The vessels were within normal limits with epiretinal membranes in both eyes. Yellowish chorioretinal lesions were present temporal to the disc in both eyes. There was a positive history of tuberculosis in the father and brother. A diagnosis of bilateral optic atrophy and epiretinal membranes secondary to presumed ocular tuberculosis was made.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"389-393"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there Co-infection of Influenza and Covid-19 in Jos, North Central Nigeria?","authors":"Nathan Yakubu Shehu, Mark Ojogba Okolo, Emmanuel Ameh Ameh, Daniel Geofrey Thankgod, Oluwatoyin Ruth Morenikeji, Ferdinand Ibu Ogbaji, Dung Davou Pam, Filibus Danjuma Dami, Pam Dachung Luka","doi":"10.71480/nmj.v66i1.342","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.342","url":null,"abstract":"<p><strong>Background: </strong>Influenza virus and severe acute respiratory syndrome virus-2 (SARS CoV-2) are known to cause respiratory disease in humans that may be fatal. They have caused epidemics and constitute significant public health challenges because of their ability to spread and cause severe disease. Co-infection with both viruses has been shown to increase the odds of fatality among affected patients. Our study aimed to investigate co-infection with influenza among patients with coronavirus disease-2019 (COVID-19) in Jos, Plateau State.</p><p><strong>Methodology: </strong>We carried out a cross-sectional study using stored nasopharyngeal and oropharyngeal samples of patients diagnosed with COVID-19 using GeneXpert. The samples were collected at our institution and stored at -80 °C. The samples were analysed for influenza co-infection using real-time reverse transcriptase polymerase chain reaction.</p><p><strong>Results: </strong>Two-hundred-and-forty-one (241) stored samples of patients diagnosed with COVID-19 were analysed. None of the samples tested positive for the influenza virus.</p><p><strong>Conclusion: </strong>We found no case of influenza and SARS-CoV-2 co-infection among the patients studied. This suggests that the prevalence of influenza virus infection may be low in our setting and partly explains the relatively benign outcome of SARS-CoV-2 infections in our region.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"357-363"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, acceptance and willingness to pay for malaria vaccine among residents of a semi-urban community in Kaduna State, North-western Nigeria.","authors":"Hanan Faridah Yusuf, Auwal Garba Suleiman, Shefaatu Shehu, Umar Yahaya, Suleiman Usman, Usman Hamisu Indabo","doi":"10.71480/nmj.v66i1.701","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.701","url":null,"abstract":"<p><strong>Background: </strong>Malaria is a life-threatening parasitic infection associated with high morbidity and mortality in endemic regions. The World Health Organization (WHO) has approved two malaria vaccines for use in children and as countries begin the phased rollout of these vaccines, uncertainties around community awareness, attitudes, and willingness to accept the vaccines remain.</p><p><strong>Methodology: </strong>This study used a multistage sampling to select 200 mostly female caregivers of children under the age of five years in Samaru, a semi-urban community in Kaduna State, North-western Nigeria. Data on knowledge, attitude, and willingness to accept the malaria vaccine was obtained using a structured questionnaire and analysed using IBM SPSS Statistics. Knowledge and attitude were scored and graded into good and poor categories. The data was presented using frequency tables and a chi-square test was used to check for associations between willingness to accept malaria vaccine and relevant variables. A <i>P</i> value < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>The majority of the respondents were females (65.5%) and married (93.0%), with a mean age of 33.1 (±9.3) years. Fifty-seven (28.5%) caregivers heard of the malaria vaccine mostly through healthcare workers and traditional media, while 39 (19.5%) showed good knowledge of the vaccine. A total of 194 (97.0%) had a good attitude towards the vaccine, 188 (94.0%) were willing to accept the vaccine, and 176 (88.0%) said they were willing to pay for it. Factors associated with vaccine acceptance included the caregiver being vaccinated as a child, having at least one child who is vaccinated, and having a good attitude toward the vaccine.</p><p><strong>Conclusion: </strong>Despite low awareness, willingness to accept the malaria vaccine was high in the community. It is recommended that immediate steps be taken by relevant stakeholders to educate the public and begin the rollout of the vaccine to avoid the spread of rumours and misconceptions.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"266-278"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}