Nigerian medical journal : journal of the Nigeria Medical Association最新文献

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Ileal Perforation and Psychosis in a 19-Year-Old Haemoglobin SC Patient-A Case Report. 一名 19 岁血红蛋白 SC 患者的回肠穿孔和精神病--病例报告。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.60787/nmj-v65i3-323
Michael Abiodun Adeyanju, Oluwakemi Bolanle Windapo
{"title":"Ileal Perforation and Psychosis in a 19-Year-Old Haemoglobin SC Patient-A Case Report.","authors":"Michael Abiodun Adeyanju, Oluwakemi Bolanle Windapo","doi":"10.60787/nmj-v65i3-323","DOIUrl":"https://doi.org/10.60787/nmj-v65i3-323","url":null,"abstract":"<p><p>Ileal perforation is a fatal surgical complication of typhoid fever. Acute psychosis occurring together with perforation presents a fatal outlook. This is made worse by these patients presenting late for appropriate intervention. A patient with sickle cell disease in addition to ileal perforation and psychosis presents a clinical picture the outcome of which is unpredictable. It could occasionally cause diagnostic dilemma and a great clinical challenge. Typhoid fever, a bacterial disease of low- income countries could be prevented by an improvement in socioeconomic conditions of the people. This will prevent or reduce to the barest minimum the occurrence of these fatal outcomes associated with its complications. This is the case report of a 19-year-old Haemoglobin SC (HbSC) with ileal perforation and acute psychosis.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness of diagnosis and treatment plan among patients in the Accident and Emergency Department of a Nigerian tertiary hospital. 尼日利亚一家三级医院急诊科病人对诊断和治疗方案的认识。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.60787/nmj-v65i3-416
Dabota Yvonne Buowari, Barile Edward Ikpae
{"title":"Awareness of diagnosis and treatment plan among patients in the Accident and Emergency Department of a Nigerian tertiary hospital.","authors":"Dabota Yvonne Buowari, Barile Edward Ikpae","doi":"10.60787/nmj-v65i3-416","DOIUrl":"https://doi.org/10.60787/nmj-v65i3-416","url":null,"abstract":"<p><strong>Background: </strong>Patient centred care has a correlation to effectiveness of patient engagement, patient care, and perceived quality of care. Even in the emergency room, awareness of diagnosis and treatment plan is a critical component in every doctor-patient interface as it enhances patient-centred care. This study aims to assess awareness of diagnosis and treatment plan among patients in the accident and emergency department.</p><p><strong>Methodology: </strong>This is a cross-sectional study conducted at the accident and emergency department of the University of Port Harcourt Teaching Hospital.</p><p><strong>Result: </strong>One hundred and ninety-seven respondents were recruited into this study comprising of 51.3% males and 48.8% females. Most 86.8% of the respondents were aware of their diagnosis, of which 91.8% knew the accurate diagnosis. Majority 84.8% of the respondents were aware of the treatment, while 68.8% of the respondents were aware of the names of the medications, most of the respondents 59.4% had no knowledge of the side effects of the medications. The majority, 61.4% were involved in the management decision. No significant relationship existed between the socio-demographic characteristics and knowledge of diagnosis and treatment plan.</p><p><strong>Conclusion: </strong>The chaotic and overcrowded nature of the accident and emergency department should not hamper the delivery of patient centred care. Although, findings obtained from this study reveal that majority of the respondents are aware of their diagnosis and treatment plan, a portion of respondents do not understand their plan of care; this indicates the need for further studies to identify interventions that would ensure that gaps in the physician -patient communication are filled as this optimizes patients' satisfaction of care received, gives better sense of control of their total situation and better quality of life.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Neuropeptide Substance P is Elevated in Sickle Cell Disease and is a Marker of Severity of Vaso-occlusive Crisis. 镰状细胞病的神经肽物质 P 升高,是血管闭塞性危象严重程度的标志。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.60787/nmj-v65i3-419
Olutoyin Adenike Olawuyi, Lateef Salawu, Mutiu Ademayowa Adeyemo, Rahman A Bolarinwa, Victor Olatunji Mabayoje, Olalekan Isaac Akerele
{"title":"The Neuropeptide Substance P is Elevated in Sickle Cell Disease and is a Marker of Severity of Vaso-occlusive Crisis.","authors":"Olutoyin Adenike Olawuyi, Lateef Salawu, Mutiu Ademayowa Adeyemo, Rahman A Bolarinwa, Victor Olatunji Mabayoje, Olalekan Isaac Akerele","doi":"10.60787/nmj-v65i3-419","DOIUrl":"https://doi.org/10.60787/nmj-v65i3-419","url":null,"abstract":"<p><strong>Background: </strong>Acute episode of pain is the most frequent symptom for which patients with sickle cell disease (SCD) seek medical attention. The neuropeptide Substance P (SP) has been suggested as a possible aetiologic factor. This study compared the serum levels of SP in SCD subjects in painful vaso-occlusive crisis with those in steady state and normal HbAA subjects.</p><p><strong>Methodology: </strong>This case-controlled study investigated eighteen SCD patients in vaso-occlusive crisis (VOC) and eighteen in steady state, while fourteen HbAA subjects were recruited as controls. Blood was collected in plain bottles and subsequently, the serum was separated for SP assay using the ELISA technique. Each sample was run, and results were confirmed in duplicate. Optical density was read at an absorbance of 450nm.</p><p><strong>Results: </strong>The study showed that SP was significantly higher in SCD patients in steady state (184.79±18.67ng/L versus 104.17±19.24ng/L) compared to the controls (t=2.97, p=0.006); while the values obtained in those in VOC (375.78±76.21ng/L) were also significantly higher (t=2.433, p=0.02) than those in steady state (184.79±18.67ng/L). The SP value in the SCD patients in VOC was almost twice as much as those in steady state and about three times as much as the value in the controls and the differences were statistically significant (t=7.72, p=0.001).</p><p><strong>Conclusion: </strong>The study showed significantly higher SP levels in VOC compared to steady state or HbAA subjects suggesting that SP may be a marker for pain sensitisation.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vaginal hysterectomy at federal teaching hospital, Katsina: A five-year review. 卡齐纳联邦教学医院的阴道子宫切除术:五年回顾
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.60787/nmj-v65i3-423
Abdulfattah Mohammed Lawal, Fatima Abubakar Rasheed, Aisha Abdurrahman
{"title":"Vaginal hysterectomy at federal teaching hospital, Katsina: A five-year review.","authors":"Abdulfattah Mohammed Lawal, Fatima Abubakar Rasheed, Aisha Abdurrahman","doi":"10.60787/nmj-v65i3-423","DOIUrl":"https://doi.org/10.60787/nmj-v65i3-423","url":null,"abstract":"<p><strong>Background: </strong>Even though the vaginal route is said to be the gynaecologist route of surgery, abdominal hysterectomy remains the predominant method of uterine removal in most parts of the world, despite the evidence of the safety of vaginal hysterectomy. The study aims to determine the prevalence, socio-demographic variables, indications as well as outcome of vaginal hysterectomy at Federal Teaching Hospital (FTH) Katsina, during the 5-year study period.</p><p><strong>Methodology: </strong>A five-year retrospective study on vaginal hysterectomy was conducted in Federal Teaching Hospital, Katsina from 1<sup>st</sup> January 2015 to 31<sup>st</sup> December 2019.</p><p><strong>Results: </strong>The rate of hysterectomies (Abdominal & Vaginal) was 21.6% of the total major gynaecological surgeries performed during the study period. Vaginal hysterectomy accounted for 6.7%. The mean age and parity of the patients were 56.06+/- 9.55 years and 10.17+/- 4.57 respectively. The commonest indication was Utero-vaginal Prolapse (88.9%) and 80.5% (29) of the patients had no complications. Most of the patients (94.4%) were discharged within 7 days of surgery and there was no fatality.</p><p><strong>Conclusion: </strong>The rate of vaginal hysterectomy in our centre is low. Most of the patients were grand multiparous with the main indication being Uterovaginal prolapse. It is associated with favourable outcomes and very low complication rates.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of prolonged QTc interval among HIV infected patients on highly active antiretroviral therapy (HAART) and its relationship with CD4 cells count and viral load at a tertiary hospital in North Eastern Nigeria. 尼日利亚东北部一家三级医院接受高效抗逆转录病毒疗法(HAART)的艾滋病毒感染者QTc间期延长的发生率及其与CD4细胞计数和病毒载量的关系。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.60787/nmj-v65i3-497
Musa Mohammed Baba, Yekeen Ayodele Ayoola, Habu Abdul, Baba Waru Goni, Fatime Garba Mairari
{"title":"Prevalence of prolonged QTc interval among HIV infected patients on highly active antiretroviral therapy (HAART) and its relationship with CD4 cells count and viral load at a tertiary hospital in North Eastern Nigeria.","authors":"Musa Mohammed Baba, Yekeen Ayodele Ayoola, Habu Abdul, Baba Waru Goni, Fatime Garba Mairari","doi":"10.60787/nmj-v65i3-497","DOIUrl":"https://doi.org/10.60787/nmj-v65i3-497","url":null,"abstract":"<p><strong>Background: </strong>Patients living with HIV infection remain at increased risk of cardiovascular diseases and sudden cardiac death. Various prevalence of electrocardiographic (ECG) abnormalities among HIV-infected patients were reported: Attamah et al reported the prevalence of electrocardiographic abnormalities among HIV-infected patients as 34.5%, while Orunta et al reported a prevalence of 42.9%, and Njoku et al reported a prevalence of 93.0%. Human immunodeficiency virus-infected patients are at increased risk of developing prolonged QT interval. Sani et al reported the prevalence of prolonged corrected QT interval among HIV-infected patients as 45.0%. Innocent et al reported a prevalence of48.0%, while Ajala et al reported a prevalence of 18%. Prolonged QTc interval increases the risk of premature ventricular contraction which can degenerate into ventricular tachycardia and or ventricular that can result in sudden cardiac death.</p><p><strong>Methodology: </strong>The study was a cross-sectional conducted among HIV-infected patients receiving HAART at the Federal Medical Centre Nguru, Yobe State, North Eastern Nigeria.</p><p><strong>Results: </strong>One hundred and seven (107) subjects were recruited into the study comprising thirty-three (37.0%) males and 70(65.4%) females. The mean CD4 cell count, and viral load of the studied patients were 612.64<b>±</b>34.75 cells/μL and4646.30<b>±</b>58.68 copies/mL respectively. Twenty (18.7%) patients had prolonged QTc interval, this gave us the prevalence of prolonged QTc in this study as 18.7%. The commonest cardiac rhythm was sinus rhythm (69.2%), followed by sinus tachycardia (26.2%) and atrial fibrillation 5(4.7%). Other electrocardiographic findings include First-degree atrioventricular block was seen in seven (6.5%) patients, Premature ventricular contractions were found in16.8%, RBBB was observed in 2.8%, 3.7% of patients had LBBB and 4.7% had left posterior hemiblock. The distribution of QTc interval according to CD4 cells count and viral revealed a statistically significant difference across the groups. All the patients with prolonged QTc interval had lower CD4 cells count and higher viral load suggesting that HIV disease severity is associated with prolonged QTc interval.</p><p><strong>Conclusion: </strong>In conclusion, the study revealed that the prevalence of prolonged QTc interval among HIV infected patients on highly active antiretroviral therapy was found to be 18.7%, and that HIV disease severity increases the risk of developing prolonged QTc interval.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tuberculosis of the Cervix Mimicking Cervical Carcinoma: Correspondence. 模仿宫颈癌的宫颈结核:通信。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.60787/nmj-v65i3-514
Hinpetch Daungsupawong, Viroj Wiwanitkit
{"title":"Tuberculosis of the Cervix Mimicking Cervical Carcinoma: Correspondence.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.60787/nmj-v65i3-514","DOIUrl":"https://doi.org/10.60787/nmj-v65i3-514","url":null,"abstract":"","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methicillin resistant staphylococcus aureus infection in neonates- a major concern and a call for action. 新生儿耐甲氧西林金黄色葡萄球菌感染--重大关切和行动呼吁。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.60787/nmj-v65i3-496
Samaha Saleh Mustapha, Musa Aishatu Zaidu, Muhammad Shamsuddeen Yusuf, Shamsudin Aliyu, Isa Abdulkadir
{"title":"Methicillin resistant staphylococcus aureus infection in neonates- a major concern and a call for action.","authors":"Samaha Saleh Mustapha, Musa Aishatu Zaidu, Muhammad Shamsuddeen Yusuf, Shamsudin Aliyu, Isa Abdulkadir","doi":"10.60787/nmj-v65i3-496","DOIUrl":"https://doi.org/10.60787/nmj-v65i3-496","url":null,"abstract":"<p><strong>Background: </strong>Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA) is both a human commensal and a pathogen that causes neonatal infection which is associated with significant morbidity and mortality. Its genetic flexibility and versatility have equipped it with the ability to develop resistance to numerous antibiotics. Outbreaks of infections in neonatal intensive care units as well as community infections have been reported mostly in developed countries. However, there is a paucity of data on neonatal MRSA infection in developing countries. The study aims to highlight cases of MRSA infection, describe the clinical presentation, and outline the antibiotic susceptibility pattern among term neonates in our facility.</p><p><strong>Methodology: </strong>It was a prospective cross-sectional hospital-based study carried out from October 2018 to July 2019. A total of 248 term neonates with suspected sepsis were enrolled in the study and had their blood samples taken for investigations including blood culture. Bacterial identification and antibiotic susceptibility patterns were carried out using MicrobactTM24E (Oxiod UK) and Staph ID and modified Kirby-Bauer disk diffusion technique respectively.</p><p><strong>Results: </strong>Out of the 248 subjects enrolled in the study, 34.2% had proven sepsis, with Staphylococcus species accounting for 56.4% of these cases. Among those with staphylococcal sepsis, 56.3% were found to have MRSA infection. Notably, the majority (94.4%) of cases originated from outside the hospital, presenting as neonatal sepsis with non-specific clinical features. Sensitivity testing revealed that ciprofloxacin and chloramphenicol were the most effective antibiotics against the identified pathogens.</p><p><strong>Conclusion: </strong>The presence of MRSA infections in neonates poses a critical public health threat. This trend underscores the emergence of antimicrobial resistance, potentially compromising treatment efficacy and jeopardizing neonatal well-being. Urgent and decisive measures are necessary to curb this trajectory.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and predictors of severe pain among patients with orofacial pain in a Nigerian Tertiary health facility. 尼日利亚一家三级医疗机构口面部疼痛患者中严重疼痛的发生率和预测因素。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.60787/nmj-v65i3-484
Amuh Veronica Obianuju, Edetanlen Benlance Ekaniyere, Hilda Itsemekpe Omere
{"title":"Prevalence and predictors of severe pain among patients with orofacial pain in a Nigerian Tertiary health facility.","authors":"Amuh Veronica Obianuju, Edetanlen Benlance Ekaniyere, Hilda Itsemekpe Omere","doi":"10.60787/nmj-v65i3-484","DOIUrl":"https://doi.org/10.60787/nmj-v65i3-484","url":null,"abstract":"<p><strong>Background: </strong>Although several studies on the pattern of oro-facial pain have been reported, none have been reported on the prevalence and risk factors of severe oro-facial pain. This study aims to determine the prevalence and predictors of severe oro-facial pain among patients in a Nigerian tertiary hospital.</p><p><strong>Methodology: </strong>The prospective cross-sectional study was conducted at the Department of Oral Diagnosis of a Nigerian tertiary hospital from January to December 2023 on all consecutive patients who presented to the centre with orofacial pains. The data collected were age, gender, occupation, level of education and marital status. Other data collected were ethnicity, smoking, alcohol intake, location of pain, causes of pain, and pain severity. Both descriptive and inferential statistics were performed. All data were analysed with SPSS version 26 (IBM Corp, Armonk, NY, US). A p-value less than 0.05 was considered significant.</p><p><strong>Results: </strong>The age range was 17-85 years with a mean age of 36.6 ±16.7 years. Almost two-thirds (64.1%) of the patients were females. Most (46.1%) of the patients were skilled workers. Almost half (48%) of the recruited patients were single. The prevalence of severe pain among patients with orofacial pain was 45.3%. There was no relationship between sociodemographic factors and the prevalence of severe orofacial pain except the ethnicity of the patients (p = 0.012)<b>.</b> There was no association between clinical factors and severe orofacial pain (p>0.05).</p><p><strong>Conclusion: </strong>The prevalence of severe pain among patients with orofacial pain was relatively high and this severity was only influenced by their ethnicity. It is therefore recommended that a high index of attention is given to orofacial pain patients and a reduction of waiting time for the same individuals.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obesity Defining Criteria, and Association with Cardiovascular Disease Risk Factors Among People Living with HIV in Jos, Nigeria. 尼日利亚乔斯艾滋病毒感染者的肥胖定义标准及其与心血管疾病风险因素的关系。
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.60787/nmj-v65i3-478
Lucius Chidiebere Imoh, Temitope Toluse Selowo, Olumide Bamidele Olaniru, Esala Ezekiel Abene, Zumnan Mark Gimba, Pantong Mark Davwar, Nathan Yakubu Shehu, Jeremiah Onubi, Christian Ogoegbulam Isichei
{"title":"Obesity Defining Criteria, and Association with Cardiovascular Disease Risk Factors Among People Living with HIV in Jos, Nigeria.","authors":"Lucius Chidiebere Imoh, Temitope Toluse Selowo, Olumide Bamidele Olaniru, Esala Ezekiel Abene, Zumnan Mark Gimba, Pantong Mark Davwar, Nathan Yakubu Shehu, Jeremiah Onubi, Christian Ogoegbulam Isichei","doi":"10.60787/nmj-v65i3-478","DOIUrl":"https://doi.org/10.60787/nmj-v65i3-478","url":null,"abstract":"<p><strong>Background: </strong>Obesity is linked to non-communicable conditions. We looked at obesity using four definable criteria and their relationship to biochemical and inflammatory indicators of cardiovascular diseases (CVDs) in people living with HIV (PLHIV).</p><p><strong>Methodology: </strong>This cross-sectional study involved 140 randomly selected HIV-infected patients attending HIV clinics at the Jos University Teaching Hospital and Faith Alive Foundation in Jos, Nigeria. Anthropometric measurements such as height, weight, waist circumference, and hip circumference were taken to identify those with obesity. Fasting plasma glucose, lipid profile, High-sensitivity CRP (hsCRP), and HIV-related markers were evaluated.</p><p><strong>Result: </strong>The mean (SD) age of the participants was 42.5 (8.8) years, and the majority (71.4%) were females. The prevalence of Obesity based on Body-Mass-Index (BMI), International Diabetes Federation (IDF), Adult Treatment Panel (ATP), and Waist-Hip-Ratio (WHR) criteria were 18.6%, 50.7% 34.3%, and 45.7% respectively. Obesity concordance among the criteria for obesity was highest between IDF and ATP (Kappa= 0.673, p<0.001); and least between BMI vs WHR (Kappa= 0.124, p<0.073). Only 9.3% had obesity by all 4 criteria. BMI was independently associated with hypertension but not glycaemic status nor dyslipidaemia while Obesity by WHR was significantly associated with hypertension and dyslipidaemia, after adjusting for age and sex. There was no significant association between Obesity by all the criteria and HIV-related parameters such as duration of HIV infection, Antiretroviral (ARV) use, and CD4 counts (p>0.05).</p><p><strong>Conclusion: </strong>Our study urges a unified assessment of obesity and a more prominent use of parameters of central obesity, for assessing cardiovascular risk in PLHIV.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Overview of Pancreatic Cancer Diagnosis and Treatment in China: Current Landscape and Future Prospects. 中国胰腺癌诊治概况:中国胰腺癌诊治概况:现状与前景
Nigerian medical journal : journal of the Nigeria Medical Association Pub Date : 2024-09-26 eCollection Date: 2024-07-01 DOI: 10.60787/nmj-v65i3-376
Sakarie Mustafe Hidig
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