Nigerian medical journal : journal of the Nigeria Medical Association最新文献

{"title":"Hydroxyurea therapy in sickle cell disease: knowledge and prescription patterns among care providers in a low-and middle-income setting.","authors":"Akinyemi O D Ofakunrin, Edache Sylvanus Okpe, Rasaq Olaosebikan, Onyeka Mary Ukpoju-Ebonyi, Tolulope Olumide Afolaranmi, Dangkat Bitrus Kilson, Stephen Oguche","doi":"10.71480/nmj.v66i1.675","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.675","url":null,"abstract":"<p><strong>Background: </strong>Hydroxyurea is a safe, effective, and well-tolerated disease-modifying therapy for patients with sickle cell disease (SCD), leading to reduced morbidity, mortality, and an improved quality of life. However, its underutilization, driven by inadequate knowledge and variability in use among SCD care providers, may limit its benefits. This study assessed the knowledge and prescription patterns of hydroxyurea among SCD care providers in Jos, Nigeria.</p><p><strong>Methodology: </strong>A cross-sectional survey of 132 physicians managing SCD was conducted to collect data on socio-demographics, hydroxyurea knowledge, and prescription patterns using a proforma. Knowledge was assessed using 17 questions (maximum score: 17). Scores above 12 (50th percentile) were classified as \"good,\" while scores of 12 or below were categorized as \"poor.\" Prescription patterns were evaluated against the National Institutes of Health (2014) and British Society for Haematology (2018) guidelines. Data were analyzed using descriptive and inferential statistics.</p><p><strong>Results: </strong>Sixty-seven (50.8%) of the 132 physicians had inadequate knowledge of hydroxyurea's clinical benefits and safety. Only 35 (26.5%) were aware of available treatment guidelines, and 32 (24.2%) had ever prescribed hydroxyurea. Among prescribers, nine (28.1%) used inappropriate criteria to initiate treatment and six (18.8%) prescribed below recommended doses. The median maximum daily prescribed dose was 750mg, whereas five (15.6%) physicians did not exceed 200mg, irrespective of patient weight. Treatment guidelines were not followed by 25 (78.1%) of prescribers.</p><p><strong>Conclusion: </strong>This study revealed a high prevalence of inadequate knowledge and inconsistent hydroxyurea prescription practices among SCD care providers. Targeted training is essential to enhance hydroxyurea utilization and ensure adherence to standardized treatment guidelines, ultimately improving patient outcomes.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"198-209"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038620/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Easing the Pain: Lignocaine Spray in Mid-Trimester Amniocentesis - A Randomized Double-Blind, Placebo-Controlled Trial.","authors":"Tanya Sharma, Meenakshi Gothwal, Charu Sharma, Pratibha Singh, Garima Yadav, Manoj Kumar Gupta, Manisha Jhirwal, Priyanka Kathuria","doi":"10.71480/nmj.v66i1.737","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.737","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the effect of lignocaine spray on maternal pain perception during mid-trimester amniocentesis compared to placebo.</p><p><strong>Methodology: </strong>This was a double-blinded, prospective, randomized controlled trial conducted at a tertiary teaching hospital in Western Rajasthan. Singleton pregnancies between 15- and 24-weeks' gestation undergoing amniocentesis were included. Participants were randomly assigned to receive either lignocaine spray or placebo (normal saline). Pain was assessed using the Visual Analogue Scale (VAS), Verbal Rating Scale (VRS), and Numerical Rating Scale (NRS). A total of 138 women were enrolled, with 69 receiving lignocaine spray and 69 receiving placebos.</p><p><strong>Results: </strong>Pain perception measured by VAS showed no significant difference between the lignocaine and placebo groups (p = 0.412). VRS and VAS demonstrated a positive correlation (r = 0.692, p < 0.001). Median VAS scores at 30 minutes post-procedure were significantly lower in the lignocaine group (p = 0.008). The Kappa agreement between VAS and VRS was found to be 59.20%. No significant difference in procedure-related complications was observed between groups.</p><p><strong>Conclusion: </strong>The study demonstrates no significant difference in VAS scores or secondary outcomes between the lignocaine and placebo groups, suggesting that lignocaine spray may not provide additional benefit for pain relief in amniocentesis.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"327-336"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of serum laminin and hyaluronic acid as markers of hepatic fibrosis in patients with chronic Hepatitis B.","authors":"Sogo Jide Busuyi, Abiodun Olabamiji Ajose, Olusegun Sylvester Ojo, Olusegun Adekanle, Olufemi Samuel Smith, Adetokunbo Oluwafunso Ajala, Omolade Adefolabi Betiku","doi":"10.71480/nmj.v66i1.653","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.653","url":null,"abstract":"<p><strong>Background: </strong>Hepatitis B virus (HBV) is a major cause of chronic liver disease worldwide. Fibrosis of hepatic parenchyma has been reported as a common pathway to complications of chronic liver disease. There is a need to monitor fibrosis in these patients to abort or delay disease progression following treatment. Liver biopsy is recognized as the gold standard for disease monitoring; however, the procedure is invasive and bedeviled with potential complications. For these reasons, non-invasive biomarkers of fibrosis are now being evaluated as alternatives to liver biopsy. The study aimed to assess the characteristics of laminin, and hyaluronic acid as markers of hepatic fibrosis in patients with chronic hepatitis B.</p><p><strong>Methodology: </strong>One hundred participants with HBV-induced chronic liver disease (CLD) were recruited for the study. A liver biopsy was conducted, and the degree of hepatic fibrosis was scored using the Metavir scoring system. Serum levels of the biomarkers were determined using enzyme-linked immunosorbent assay (ELISA) technique. Medians and interquartile ranges were compared using the Mann-Whitney U test. The degree of correlation between continuous variables was determined using Spearman's correlation analysis. Statistical significance was set at p ≤ 0.05.</p><p><strong>Results: </strong>Serum laminin was significantly higher in participants with hepatic fibrosis: 39.09 (27.6-89.4) ng/ml [median (interquartile range)], vs 24.3 (21.5-31.9) ng/ml, p = 0.001, Hyaluronic acid was significantly higher in participants with hepatic fibrosis: 45.1 (26.9-94.4) ng/ml vs 23.1 (12.7-35.7) ng/ml, p < 0.001. There was a strong significant positive correlation of both serum laminin and hyaluronic acid with Metavir score in the study participants (r=0.766, p<0.001; r=0.708, p<0.001 respectively). At a serum laminin concentration of 44.6 ng/ml, sensitivity and specificity for detecting moderate to severe hepatic fibrosis were 86.8% and 88.7% respectively, with an area under the curve (AUC) of 0.943 on the Receiver Operator Characteristic (ROC) curve. The sensitivity and specificity of hyaluronic acid for detecting moderate to severe hepatic fibrosis were 81.6% and 85.5% at a serum concentration of 53.5 ng/ml. AUC was 0.930 on the ROC curve.</p><p><strong>Conclusion: </strong>This study underscores the evidence that laminin and hyaluronic acid may be helpful clinically in identifying patients with moderate to severe hepatic fibrosis. Serum laminin had a slightly better diagnostic ability than hyaluronic acid in the study participants. Further studies are needed to elucidate our findings.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"156-164"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Pattern of Medical Admissions at the Intensive Care Unit of the University of Port Harcourt Teaching Hospital, Nigeria.","authors":"Otokwala Job Gogo, Akpa Maclean Romokere, Stanley Rosemary Oluchi","doi":"10.71480/nmj.v66i1.742","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.742","url":null,"abstract":"<p><strong>Background: </strong>Intensive care units offer specialized care to critically ill patients and are an integral part of modern health care. In low-income countries, with limited resources, the demand to optimize patient care and improve outcomes depends on a better understanding of the pattern of medical referrals to the ICU for varying reasons of resource allocation, staffing, and quality improvement initiatives. This study aims to describe and provide valuable insights into the patterns of medical admissions to the intensive care unit (ICU), including case mixes, intensive care interventions, duration of stay, and outcomes to highlight the need for proper resource allocation.</p><p><strong>Methodology: </strong>A retrospective descriptive study was conducted at the University of Port Harcourt Teaching Hospital ICU between January 2022 and December 2024. We reviewed all patients from the Department of Internal Medicine referred to the ICU with a purely medical diagnosis. Data were retrieved from the ICU admissions register and patients' medical records following ethical exemption approval.</p><p><strong>Results: </strong>A total of 377 patients with medical referrals were reviewed, accounting for approximately 56.9% of all ICU admissions. More males were admitted, and the mean age of patients was 48.6 ± 15.3 years. The emergency unit was the commonest source of referral and offered a significant source of in hospital delays prior to transfer to the ICU. The most common indication for ICU admission was stroke, with hemorrhagic stroke, sepsis, and cardiogenic shock associated with the worst outcomes.</p><p><strong>Conclusion: </strong>Stroke predominated medical referrals and provided the worst outcome. The in-hospital delays at the emergency unit which became the largest source of referral contributed to the high mortality. This study highlights the need to strengthen stroke care at the tertiary level of care as well as other medical referrals to improve care.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"337-346"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing Single Dose Versus Multiple Doses Antibiotic Prophylaxis in Preventing Surgical Site Infections Following Open Appendicectomy for Uncomplicated Appendicitis.","authors":"Onoriode Brotobor, Deliverance Brotobor, Jemima U Mukoro, Adedamola R Odeyale","doi":"10.71480/nmj.v66i1.670","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.670","url":null,"abstract":"<p><strong>Background: </strong>Acute appendicitis is the leading cause of acute surgical abdomen. Studies have shown that a single dose of antibiotics is as effective as multiple doses in preventing surgical site infections (SSI) after appendectomy, with advantages such as cost savings, fewer adverse reactions, and reduced risk of antibiotic resistance. Despite these benefits, multiple doses are still commonly used. This study compared the efficacy of single-dose versus multiple-dose antibiotic prophylaxis in preventing SSI after open appendectomy for uncomplicated appendicitis.</p><p><strong>Methodology: </strong>A one-year prospective study was conducted at the university of Benin teaching hospital (UBTH), Benin City, involving 62 adult patients with uncomplicated appendicitis. A total of 76 patients were initially recruited, but after histological evaluation, 62 patients were analyzed, 29 received a single dose of antibiotics, and 33 received multiple doses following the exclusion of the negative appendicectomies. All patients were given intravenous 1.5 g cefuroxime and 500 mg metronidazole at anesthesia induction, with the multiple-dose group receiving two additional doses. Outcomes assessed included SSI occurrence, cost of antibiotics, and SSI management costs.</p><p><strong>Results: </strong>SSI rates were similar between groups (3.5% vs. 3.0%), but the cost of multiple-dose regimens was over twice that of single-dose. Side effects were more frequent with multiple doses. Both SSI cases were superficial and associated with higher BMI.</p><p><strong>Conclusion: </strong>Single-dose antibiotic prophylaxis is equally effective, more economical, and safer than multiple doses.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"187-197"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Sexual Life and its Correlates among Men with Diabetes Mellitus and Erectile dysfunction attending a tertiary hospital in Owerri, Nigeria.","authors":"Patrick Chinedu Obi, Ginikanwa Helga Njoku, Adaure Chibuzo Mbaike, Augustine Chinedu Ihim, Okechukwu Francis Nwako, Anthony Chinedu Anyanwu, John Uchechukwu Ohiri, Ernest Nwazor, Blessing Chinenye Ubani, Stanley Ugochukwu Ogbonna, Mafuka Johnson Simon, Reginald Nnamdi Oputa","doi":"10.71480/nmj.v66i1.523","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.523","url":null,"abstract":"<p><strong>Background: </strong>Erectile dysfunction (ED) is common among men with Diabetes mellitus (DM), with a negative impact on their sexual satisfaction. There is a paucity of data on this in our locality. Hence this study was to determine the quality of sexual life, its correlates and predictors among such men.</p><p><strong>Methodology: </strong>One hundred diabetic men with ED as well as 100 without ED were recruited consecutively. Questionnaires were used to collect relevant information and assess their quality of sexual life. This was followed by a focused physical examination and anthropometric measurements. Blood samples were collected for relevant investigations. Data analysis was with SPSS version 25 while p-value < 0.05 was considered significant.</p><p><strong>Results: </strong>Participants with ED had a mean IIEF-5 score of 11.97 ± 4.73 while those without ED had 24.06 ± 1.10 (p = 0.000). Among the DM participants with ED and those without ED, their mean SQoL-M scores were 44.14 ± 10.85% and 89.73 ± 16.23% respectively (p = 0.000). Correlation between SQoL-M scores and IIEF-5 scores showed (r = 0.374, p = 0.000) while that between SQoL-M scores and HbA1c showed (r = - 0.205, p = 0.040) in diabetic participants with ED. IIEF-5 scores and HbA1c levels were observed to be the only predictors of SQoL scores among diabetic participants with ED.</p><p><strong>Conclusion: </strong>There is a significant difference in the quality of sexual life between diabetic men with ED and those without ED. While there is a positive correlation between SQoL-M and IIEF-5 scores, there is a negative correlation between SQoL-M scores and HbA1c levels among diabetic men with ED. IIEF-5 scores and HbA1c values are predictors of quality of sexual life among diabetic men with ED. Thus, there is a need for evaluation of quality of sexual life among diabetic men with ED.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"36-43"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Compliance to Preventive Measures against COVID-19 using WHO Checklist among Secondary Schools in Nnewi North Local Government Area of Anambra State, Nigeria.","authors":"Vivian Amarachi Aguwamba, Dominic Udodirim Emezuru, Ugochukwu Anthony Aguwamba","doi":"10.71480/nmj.v66i1.645","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.645","url":null,"abstract":"<p><strong>Background: </strong>Coronavirus Disease of 2019 (Covid-19) was arguably the greatest global health threat of our time. Immediately the pandemic was declared by WHO, countries around the world took broad public health and social measures (PHSM), including closure of schools, to prevent the spread of the SARS-CoV-2 virus, which causes COVID-19. The COVID-19 pandemic posed an enormous risk to the health and safety of learners, teachers, parents, school administrators, education practitioners, and the wider community. However, reopening schools carried the public health risk of viral resurgence. This study aimed to assess the compliance to COVID-19 preventive measures among secondary schools in Nnewi North LGA of Anambra state, Nigeria using WHO checklist.</p><p><strong>Methodology: </strong>This was a facility-based cross-sectional observational survey of secondary schools within Nnewi North local government area of Anambra state. Data was collected through school surveys and observations of compliance measures, both done during the same school visit. Informed consent was obtained from the principal of each school or their representative before carrying out the study in their facilities.</p><p><strong>Results: </strong>Out of the schools sampled, 12 schools (38.71%) had good compliance, 9 schools (29.03%) had moderate compliance, and 10 schools (32.26%) had poor compliance. The finding of this study thus revealed that the overall compliance level toward COVID-19 preventive and control measures among secondary schools in Nnewi-North LGA of Anambra state was 38.71%.</p><p><strong>Conclusion: </strong>The common restraining factors against compliance to standard COVID-19 preventive measures included the fact that the students are children (aged between 11 - 18 years) and thus wouldn't always wear their masks, school ownership, attitude towards, and risk perception of COVID-19 and these factors significantly influenced the adherence of each school towards COVID-19 mitigation measures.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"127-141"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern and Outcome of Medical Admissions at the University of Uyo Teaching Hospital: A 5-Year Hospitalization Analysis.","authors":"Effiong Ekong Akpan, Aniema Isaac Asam Udo, Idongesit Odudu Umoh, Bertha Chioma Ekeh, Victor Aniedi Umoh, Anyiekere Morgan Ekanem, Udeme Ekpenyong Ekrikpo","doi":"10.71480/nmj.v66i1.678","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.678","url":null,"abstract":"<p><strong>Background: </strong>The pattern of hospital admission is necessary for proper planning and budgeting in health care. It also provides insights into the burden of disease in a particular community. Additionally, admission patterns also assist in reviewing the morbidity and mortality over the duration of the study and allow for proper planning and prevention of these occurrences.</p><p><strong>Methodology: </strong>This is a five-year retrospective study of patients admitted to the medical wards. Patients' case notes were retrieved from the hospital's records department. Demographic data such as age, sex, occupation, and religion were extracted from the case notes. Clinical data such as diagnosis, date of admission and discharge, duration of stay, and cause of death were also extracted. Kaplan-Meier survival curves were plotted, and a multivariate Cox proportional hazards model was used to determine the independent predictors of mortality.</p><p><strong>Results: </strong>A total of 2634 patient records were retrieved. The ages of patients ranged from 15 to 102 years, with a mean of 54.8 ± 16.5 years. There were more males 1374 (52.2%) against 1269(47.8%) females), p<0.001. Noncommunicable diseases (NCDs) accounted for 2286 (86.8%), with 348 (13.2%) being communicable diseases. Chronic kidney disease (CKD) 21.5%, acute kidney injury (5.0%), Stroke (19.9%), Heart failure (17.6%), and Diabetes (20.7%) were the leading NCDs. On the other hand, Tuberculosis (4.0%), and Pneumonia (1.4%), were the leading communicable diseases causing hospitalization. Older age groups ≥60 years (p= 0.02), kidney disease, (p< 0.001). HIV. (p=0.01) were independently associated with mortality.</p><p><strong>Conclusion: </strong>The epidemiological transition to NCDs is well established in the adult population of Akwa Ibom State. Older age, kidney diseases, stroke, and HIV infection were independent predictors of mortality.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"210-224"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Purple Urine Bag Syndrome: A Case Report of An Elderly Nigerian Woman.","authors":"Ibitrokoemi Faye Korubo, Ekechi Stella Amadi, Chikeka Chimaroke Ukachi","doi":"10.71480/nmj.v66i1.693","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.693","url":null,"abstract":"<p><p>Purple urine bag syndrome (PUBS) is an unusual presentation of urinary tract infection (UTI). Few cases have been reported in Africa. We present a case report of Purple Urine Bag Syndrome from the Niger Delta region of Nigeria. The patient was a bedridden catheterized 71 -year-old quadriplegic female patient with a history of hypertension, and ischemic stroke. She was treated with a course of appropriate antibiotics and by changing her urinary catheter and bag. The patient's caregiver refused further care and signed against medical advice after forty-eight hours of admission without doing the requested investigations. Purple urine bag syndrome (PUBS) is a rare benign condition with a good prognosis.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"385-388"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic predictors of knowledge and practice of exclusive breastfeeding among mothers attending primary health centres in Ethiope West, Delta State Nigeria.","authors":"Aruoriwo Ajiroghene Okwesa, Nyemike Simeon Awunor, Mamodesan Tudjegbe Okumagba, Augustine Ossai Okwesa, Efe Abolodje","doi":"10.71480/nmj.v66i1.695","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.695","url":null,"abstract":"<p><strong>Background: </strong>A mother's sociodemographic characteristics influence her practice of breastfeeding and are vital in determining the overall well-being of the baby. This study assessed the sociodemographic predictors of the knowledge and practice of exclusive breastfeeding among lactating mothers attending primary health centres in Ethiope West LGA of Delta State.</p><p><strong>Methodology: </strong>This cross-sectional questionnaire-based study was conducted among 360 mothers of children aged 6-15 months attending six primary health centres in Ethiope West Local Government Area of Delta State. Data was collected on sociodemographic factors, knowledge, and practice of exclusive breastfeeding among mothers. There were 8 questions that assessed the knowledge of exclusive breastfeeding. A mother was assessed to have good knowledge of exclusive breastfeeding when she answered correctly at least 6 out of the 8 questions. Data was analyzed using IBM SPSS Version 26.0.</p><p><strong>Results: </strong>The respondents were aged 15-41 years with the majority (47.4%) being 20-29 years and a mean age of 28.92±6.89 years. They were mainly Urhobos (62.8%), married (78.9%), with about half (50.6%) of the participants in the lowest social class and about 43.3% having at least a secondary education. Most (78%) respondents had a good knowledge of exclusive breastfeeding but only about one-third (36%) were exclusively breastfed. Logistic regression analysis showed the odds of practicing EBF to be about twice in married women compared to the unmarried (AOR= 1.90, 95% CI= 1.007-3.591, p=0.014) and that the level of education was predictive of knowledge of EBF (AOR= 12.89, 95% CI= 4.006-40.901; p=0.001).</p><p><strong>Conclusion: </strong>Despite the good knowledge of EBF, its practice was poor with marital status being the most important predictor of EBF.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"235-245"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}