Nigerian medical journal : journal of the Nigeria Medical Association最新文献

{"title":"From Void to Victory: Managing Open Apices with Mineral Trioxide Aggregate (MTA)- A Descriptive Case Series.","authors":"Prabhleen Kaur Brar, Rajdeep Brar, Shipra Gupta, Phavithrasri Kannan, Ramandeep Singh Gambhir","doi":"10.71480/nmj.v67i5.1418","DOIUrl":"10.71480/nmj.v67i5.1418","url":null,"abstract":"<p><p>Mineral trioxide aggregate (MTA) apexification is a predictable treatment for immature permanent teeth with necrotic pulps and open apices, offering superior sealing, biocompatibility, and shorter treatment duration than conventional calcium hydroxide. This descriptive case series evaluated three non-vital immature incisors with open apices and periapical radiolucencies following trauma or presenting with discoloration and pain. One tooth received an apical MTA plug followed by gutta-percha obturation, while two underwent MTA obturation. All teeth were restored and clinically and radiographically followed for 6-12 months. All cases demonstrated resolution of symptoms, reduction of periapical radiolucencies, and satisfactory healing, with the treated teeth remaining functional and asymptomatic. No postoperative complications occurred. These findings suggest that MTA apexification and obturation are effective treatment options for immature permanent teeth with necrotic pulps and open apices. Their favourable outcomes, reduced treatment time, and potential to improve the prognosis of structurally compromised teeth support their clinical use.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"67 5","pages":"1895-1904"},"PeriodicalIF":0.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroschistosomiasis Mimicking Spinal Tuberculosis: A Case Report.","authors":"Muhammadu Sani Abubakar, Jabiru Muazu, Abdulwahab Elladan Yusuf, Nasir Bakiyawa Abubakar, Salisu Aliyu","doi":"10.71480/nmj.v67i5.1428","DOIUrl":"10.71480/nmj.v67i5.1428","url":null,"abstract":"<p><p>Schistosomiasis is a chronic parasitic disease acquired through freshwater exposure, in which cercariae penetrate the skin and mature into adult worms. Disease manifestations largely result from granulomatous inflammation and fibrosis surrounding retained eggs. A 65-year-old widow presented with six months of lower back pain, weight loss, paraplegia (power 1/5), sphincter dysfunction, a T12 sensory level, and T9-T10 gibbus. She had received empirical antitubercular therapy for two months without improvement. Thoracolumbar MRI demonstrated vertebral and disc collapse at T10-T11 and L1-L2, with adjacent paravertebral abscesses and cord compression. Surgical biopsies revealed numerous calcified Schistosoma haematobium eggs with terminal spines, surrounded by granulomas containing epithelioid histiocytes, foreign-body giant cells, lymphocytes, and eosinophils. She received weekly praziquantel (1,200 mg) and tapered prednisolone. Motor power improved to 2/5, although urinary and faecal incontinence persisted. Neuroschistosomiasis should be considered in endemic regions, particularly when presumed spinal tuberculosis fails to respond to treatment. Definitive diagnosis requires careful clinicoradiological and histopathological evaluation.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"67 5","pages":"1910-1915"},"PeriodicalIF":0.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High rate of Healthcare Associated Infections in a Nigerian Tertiary Hospital: A Point Prevalence Survey Highlighting Neonatal and Paediatric Vulnerability.","authors":"M Z Sabitu, Y Mohammed, O O Oduyebo, T Yusuf, I N Nwafia, I W Isa Musa, B G Aljannare, J Abubakar, Y Saminu, K M Dada, H Mathew, U Faruk, A Versporten","doi":"10.71480/nmj.v67i5.1427","DOIUrl":"10.71480/nmj.v67i5.1427","url":null,"abstract":"<p><strong>Background: </strong>Healthcare-associated infections (HAIs) are a major patient safety threat globally, with high burdens in low- and middle-income countries (LMICs). In Nigeria, data on HAIs are limited, affecting effective infection prevention and control (IPC) strategies. This study evaluated the prevalence, types, and risk factors of HAIs at Usmanu Danfodiyo University Teaching Hospital (UDUTH) using the Global Point Prevalence Survey (GPPS) HAIs section.</p><p><strong>Methodology: </strong>A cross-sectional point prevalence survey was conducted from 21-25 October 2024 across all inpatient wards using standardised GPPS protocols. All patients admitted before 08:00 on survey days were included. Data were collected on the presence of HAIs, infection types, invasive device use, prior hospitalisations, surgery during admission, and severity of underlying conditions using the McCabe score. Comparisons between patients with and without HAI were made using chi square.</p><p><strong>Results: </strong>Among 262 inpatients, HAI prevalence was 14.5% (38/262), with significantly higher prevalence in paediatric/neonatal wards than adult wards (31.0% vs 11.4%; p = 0.001). Common HAIs included other infections (6.5%), bloodstream infections (5.3%), and surgical-site infections (2.7%). HAIs were associated with peripheral vascular catheter use, surgery, and fatal McCabe score. Peripheral vascular catheters were most frequently used (78.2%), followed by urinary (27.1%) and central venous catheters (1.5%).</p><p><strong>Conclusion: </strong>UDUTH revealed a high rate of HAIs, particularly affecting vulnerable children and neonatal populations, with bloodstream infections among the most reported types. These findings underscore an urgent need for improved IPC programmes, strengthened surveillance systems, targeted interventions in high risk wards, and enhanced diagnostic capacity to guide HAIs prevention strategies.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"67 5","pages":"1846-1855"},"PeriodicalIF":0.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential Drug-Drug Interactions and Adverse Drug Reactions Among Elderly Psychiatric Outpatients Receiving Antipsychotics: A Cross-Sectional Study.","authors":"Sumit Kumar Mahato, T Y Sree Sudha, Kusum Kumari, Jameema Liza Thankachan, V Veena, Ayoshi Mondal","doi":"10.71480/nmj.v67i5.1361","DOIUrl":"10.71480/nmj.v67i5.1361","url":null,"abstract":"<p><strong>Background: </strong>Older adults with psychiatric illness often take long-term antipsychotics along with medicines for chronic diseases, increasing the risk of potential drug-drug interactions (pDDIs) and adverse drug reactions (ADRs). Indian outpatient data are limited. The main objective of this study was to describe pDDIs involving antipsychotics and assess associated ADRs in elderly psychiatric outpatients (frequency, mechanism, severity).</p><p><strong>Methodology: </strong>The present study was a cross-sectional study, in which 105 elderly psychiatric outpatients who were on stable antipsychotics plus chronic disease therapy were enrolled. Prescriptions were screened for pDDIs using Epocrates and Medscape and classified by mechanism (pharmacodynamic, pharmacokinetic, or mixed) and severity. ADRs were documented using ICSR, with causality assessed by the Naranjo algorithm and severity by the Hartwig-Siegel scale. Ethical approval was obtained from the Institute Ethical Committee. Descriptive and bivariate analyses (chi-square, Welch's t-test) were performed.</p><p><strong>Results: </strong>Mean age was 69.0 ± 4.7 years; 54.3% were male, and patients used a mean of 2.18 medications. Depressive (27.6%) and anxiety disorders (25.7%) were most common; hypertension (29.5%) and diabetes (18.1%) were leading comorbidities. Ninety-nine drug pairs were evaluated, predominantly pharmacodynamic (72.7%). Most were rated \"no interaction\" (63.6-70.7%), while 27.3% required \"monitor closely.\" ADRs occurred in 52.4% (n=55), mainly mild (41.8%) or moderate (47.3%); 10.9% were severe. ADRs were more frequent in older patients (mean difference 1.96 years; p=0.034) and males (OR 3.65; p=0.0027).</p><p><strong>Conclusion: </strong>pDDIs are common in elderly psychiatric outpatients and often warrant close monitoring to reduce ADRs. Routine screening and multidisciplinary medication review may improve safety.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"67 5","pages":"1836-1845"},"PeriodicalIF":0.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acinar Cell Carcinoma of the Pancreas: A Three Case Series and Literature Review.","authors":"Raheem Nasiru, M C Dahiru Aminu, Dauda W Wadinga, Peter Isaac, S Jika Aminu, Jangle Nancwat Lohbut, L Appah Douglas","doi":"10.71480/nmj.v67i5.1457","DOIUrl":"10.71480/nmj.v67i5.1457","url":null,"abstract":"<p><p>The pancreas is predominantly composed of acinar cells, yet malignant transformation of these cells is uncommon. Acinar cell carcinoma (ACC) is a rare pancreatic neoplasm, accounting for approximately 1-2% of pancreatic tumours in adults. It commonly arises in the pancreatic head and, unlike pancreatic ductal adenocarcinoma, often presents without jaundice. We report the clinicopathological features of three patients diagnosed with ACC at our institution. Case 1 was a 40-year-old man with recurrent vomiting, epigastric pain, weight loss, early satiety, and a 20-pack-year smoking history. Case 2 was an 82-year-old who presented with recurrent abdominal pain, distension, jaundice, weight loss, and vomiting, and died shortly after admission; autopsy revealed widespread intra-abdominal tumour. Case 3 had a similar clinical presentation. Histology confirmed ACC in all three cases. Case 1 underwent surgery and chemotherapy, while Case 3 received chemotherapy alone. ACC should be considered in the differential diagnosis of pancreatic masses causing gastric outlet obstruction, particularly in the absence of jaundice.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"67 5","pages":"1916-1924"},"PeriodicalIF":0.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Mother's Self-Efficacy, Social Support &amp; Intention on Exclusive Breastfeeding: A Systematic Review.","authors":"S Malar Kodi, Prasuna Jelly, Chandrakala Sankarapandian, Anand Lakshminarasimhan","doi":"10.71480/nmj.v67i5.1364","DOIUrl":"10.71480/nmj.v67i5.1364","url":null,"abstract":"<p><p>Breastmilk is widely considered to be the best source of nutrition for infants. Psychosocial factors such as maternal attitude, intention, self-efficacy and social support may influence EBF practice. The study aimed to examine the influence of mothers' self-efficacy, social support, and intention on their decision to breastfeed exclusively. A systematic and comprehensive search was conducted across four databases (PubMed, Scopus, Embase, CINAHL) from 2010 to 2024. Observational studies assessing psychosocial determinants of EBF were included. The screening of studies, the methodological quality assessment of selected studies using the Newcastle-Ottawa scale, and the analysis were performed independently by four reviewers. Study selection followed PRISMA guidelines, and findings were synthesised narratively. A total of 16 studies conducted across various countries were included, revealing that the majority of mothers initiate breastfeeding within 1-6 hours. Non-working mothers had higher EBF rates, whereas employed mothers had lower rates of exclusively breastfed infants. Most studies reported positive associations between breastfeeding self-efficacy, intention, social support and EBF practices. The review highlights the need for improved antenatal education, practical support, and counselling from healthcare providers to increase breastfeeding rates and mothers' confidence.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"67 5","pages":"1667-1683"},"PeriodicalIF":0.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness, Willingness and Self-Reported Eligibility Characteristics for Blood Donation Among Young Undergraduates of David Umahi Federal University of Health Sciences, Uburu, Ebonyi State, Nigeria.","authors":"Eric Okorie Nwaze, Francis Idenyi Onwe, Victor Sochima Ngwuta, Josephine Adejoh","doi":"10.71480/nmj.v67i5.1465","DOIUrl":"10.71480/nmj.v67i5.1465","url":null,"abstract":"<p><strong>Background: </strong>Nigeria continues to face shortages of safe blood, with substantial reliance on family replacement donors. University students are young, accessible and potentially suitable for repeat voluntary donation, but institution-specific evidence is needed to guide safe campus donor mobilisation. This study assessed awareness, knowledge, willingness, previous donation practice and self-reported eligibility characteristics for blood donation among undergraduates of David Umahi Federal University of Health Sciences (DUFUHS), Uburu, Nigeria.</p><p><strong>Methodology: </strong>A descriptive cross-sectional study was conducted among DUFUHS undergraduates in September 2025. The minimum sample size was 334 after finite population correction; 352 students were approached to allow for incomplete or unusable questionnaires, and 334 complete questionnaires were analysed, giving a usable response rate of 94.9%. Data were collected using a structured, pre-tested questionnaire adapted from previous blood donation studies. Variables included socio-demographic characteristics, awareness, knowledge, willingness, previous donation and self-reported eligibility characteristics. Data were analysed using IBM SPSS Statistics version 23.0. Categorical variables were summarised as frequencies and percentages, and associations were assessed using chi-square or Fisher-Freeman-Halton exact tests at p < 0.05.</p><p><strong>Results: </strong>The mean age was 19.43 ± 2.98 years, and 248 (74.2%) respondents were female. Awareness of the blood donation process was reported by 172 (51.6%), while 162 (48.4%) were familiar with eligibility requirements. Only 51 (15.4%) were likely to donate within six months, 69 (20.7%) met the predefined willingness criterion, and 310 (92.9%) had never participated in blood donation drives.</p><p><strong>Conclusions: </strong>Awareness was moderate, but willingness and previous donation practice were low. DUFUHS should implement regular campus blood donation drives, peer donor clubs, targeted social media education and formal collaboration with authorised blood transfusion services.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"67 5","pages":"1856-1868"},"PeriodicalIF":0.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testicular Schistosomiasis Mimicking Testicular Tumour: A Case Report.","authors":"Auwal Idris Kabuga, Rufai Yunusa, Ahmad Hamza, Nura Yusuf, Musbahu Yusuf, Muhammad Yaseen Hassan","doi":"10.71480/nmj.v67i5.1423","DOIUrl":"10.71480/nmj.v67i5.1423","url":null,"abstract":"<p><p>Schistosomiasis is a neglected tropical disease, with the highest burden in Sub-Saharan Africa, predominantly due to Schistosoma haematobium. Testicular involvement is rare; fewer than 30 cases have been reported in the literature to date, though sporadic reports continue to emerge from endemic areas. We report the case of a 34-year-old school teacher from Kano, Nigeria, with a history of freshwater exposure and childhood schistosomiasis treated with praziquantel. He presented with a two-year history of a firm, progressively enlarging left hemi-scrotal mass. Clinical examination and scrotal ultrasound were both suggestive of a testicular tumour. The patient underwent left radical orchidectomy. Histopathological examination, independently verified by three pathologists, revealed calcified Schistosoma ova within a densely fibrotic, granulomatous background, with no evidence of malignancy. This case underscores testicular schistosomiasis as an important differential diagnosis for testicular masses in endemic regions, and highlights the central role of histopathology in preventing unnecessary orchidectomy.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"67 5","pages":"1904-1909"},"PeriodicalIF":0.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Etiological Pattern of Infertility in Women Presenting to a Gynecology Clinic in a Secondary Health Facility, South-South, Nigeria: A Cross-Sectional Study.","authors":"Ngozi Roy Maduka, Samuel Okwuchukwu Ilikannu","doi":"10.71480/nmj.v67i5.1192","DOIUrl":"10.71480/nmj.v67i5.1192","url":null,"abstract":"<p><strong>Background: </strong>Infertility is a major reproductive health problem with significant social, psychological, and economic consequences. In Nigeria, cultural expectations surrounding childbearing may intensify stigma and emotional distress, particularly among women. This study aimed to determine the prevalence and causes of infertility among women attending the Gynaecology Clinic of Central Hospital Agbor.</p><p><strong>Methodology: </strong>This cross-sectional study involves all women presenting with infertility who completed the basic fertility investigations at the CHA gynecology clinic between January 1^st and December 31^st, 2024. Participants were recruited after obtaining informed consent using a consecutive sampling technique over a period of one year. A data extraction form was used to document the sociodemographic characteristics, clinical history, and investigation results. The data were analyzed using IBM SPSS for Windows, version 25.</p><p><strong>Results: </strong>The average age of the participants in the study was 32.5 ± 5.8 years. The study found an infertility prevalence of 34.4%, with primary and secondary infertility comprising 41.3% and 58.7%, respectively. The commonest associated factor responsible for infertility in this study was male factor infertility, 37.4%, while female, combined, and unexplained factors made up 33.0%, 16.0%, and 13.6%. Tubal blockage was the most commonly identified factor associated with female infertility (19.4%), while Anovulation, endometriosis, and uterine fibroids were the associated factors in 14.1%, 9.7%, and 8.7%, respectively.</p><p><strong>Conclusion: </strong>This study highlights a high infertility rate of 34.4% among women presenting to a gynecology clinic in South-South Nigeria, with male infertility being the predominant factor. This underscores the need for comprehensive evaluation and management of both partners in infertility cases, emphasizing the importance of male factor assessment in addressing this significant public health concern.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"67 5","pages":"1752-1762"},"PeriodicalIF":0.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics of Sickle Cell Disease Patients with Leg Ulcer in Murtala Muhammad Specialist Hospital, Kano, Nigeria.","authors":"Awwal Musa Borodo, Usman Muhammad Ibrahim, Hauwa Ibrahim","doi":"10.71480/nmj.v67i5.1334","DOIUrl":"10.71480/nmj.v67i5.1334","url":null,"abstract":"<p><strong>Background: </strong>Sickle cell disease (SCD) is an inherited chronic haemolytic disorder in Nigeria. It is associated with significant morbidity and mortality. This study aimed to review the clinical characteristics of patients with leg ulcers attending the adult clinic of sickle cell disease in Murtala Muhammad Specialist Hospital, Kano, Nigeria.</p><p><strong>Methodology: </strong>This is a retrospective descriptive study that analysed the records of 31 patients with leg ulcers registered with the sickle cell clinic of MMSH, Kano, Nigeria from July 2019 to December 2022. Data were analysed using the Statistical Package for the Social Sciences (SPSS) version 12.0.</p><p><strong>Results: </strong>The minimum and maximum age of the patients were 15 years and 38 years, respectively, with a mean± SD of 23.4±6.5. More than a quarter of the patients (38.7%) were traders. The majority of the patients (71.0%) had a single leg ulcer, while more than a quarter (29%) had multiple ulcers. About two-thirds of the patients (64.5%) had an ulcer duration of less than 6 weeks. The majority of the patients had a history of blood transfusion in the past. About one-fifth of the patients (22.6%) had a history of hospitalization in the last 1 year, while 81% of the patients had a history of at least one vaso-occlusive crisis event in the last 1 year. One-third of the patients (32 %) of the patients had 3 or more vaso-occlusive crisis events in the last 1 year. About half of the male patients (45%) had a prior history of priapism in the past.</p><p><strong>Conclusion: </strong>The majority of the sickle cell disease patients with leg ulcer in MMSH are males, with chronic ulcers and a history of prior blood transfusion. Government and clinicians should intensify health promotional activities and preventive interventions to prevent sickle cell disease-associated complications like leg ulcer.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"67 5","pages":"1880-1885"},"PeriodicalIF":0.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}