Nigerian medical journal : journal of the Nigeria Medical Association最新文献

{"title":"Beyond Grades: Harnessing Self-Regulated Learning to Empower Underperforming Students.","authors":"Shree Lakshmi Devi Singaravelu, Abilash Sasidharannair Chandrakumari","doi":"10.71480/nmj.v66i1.689","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.689","url":null,"abstract":"<p><p>Self-regulated learning (SRL) represents a critical educational framework through which learners proactively govern their learning processes using self-motivation, metacognitive reflection, and strategic task management. This article examines SRL's transformative role in enhancing academic performance, particularly for underperforming students who often face significant academic and environmental challenges. SRL offers a structured approach for these students by promoting resilience and reinforcing goal-oriented learning behaviors. Key SRL components include establishing structured learning environments, optimizing resource use, and building self-efficacy. Through SRL instruction, educators can support underperformers in cultivating sustainable, autonomous learning practices. Specific strategies, such as peer tutoring and interactive tools like \"Betty's Brain,\" reinforce understanding as students teach and apply learned concepts. Integrating SRL among underperforming students cultivates lifelong learning skills and establishes a foundation for enduring academic and professional success. Future research should explore innovative SRL approaches tailored to the needs of underperforming students, with particular emphasis on applications within medical education, where SRL could significantly enhance both immediate and long-term outcomes.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"26-35"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life in children with epilepsy: Effect of socio-demographic factors and Parental awareness of seizure action plan in Eastern India.","authors":"Aishwarya Senapaty, Preeti Srivastava, Shikha Swaroop, Roshan Mohanty, Adyasha Mishra","doi":"10.71480/nmj.v66i1.690","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.690","url":null,"abstract":"<p><strong>Background: </strong>Epilepsy is a chronic neurological disorder that disrupts daily life and negatively impacts quality of life (QOL). While most medical approaches focus on seizure control, there is limited attention to the QOL of children with epilepsy (CWE) in eastern India. This study aimed to assess QOL among CWE and examine the influence of sociodemographic factors, seizure characteristics, and parental awareness of a seizure action plan (SAP).</p><p><strong>Methodology: </strong>This cross-sectional study was conducted in the Department of Paediatrics at a tertiary care teaching hospital in eastern India from December 2020 to May 2022. Eighty children aged 5-15 years, all diagnosed with epilepsy and on antiepileptic medication for at least six months, participated. Approval was obtained from the Institutional Ethics Committee of the hospital concerned. The participants were interviewed using a structured pre-tested schedule. The QOL of the participants was evaluated using the Quality of Life in Childhood Epilepsy (QOLCE-55) questionnaire. Parental awareness of SAP was assessed based on their knowledge of essential seizure management actions. Kruskal Wallis test was used to identify factors associated with QOL.</p><p><strong>Results: </strong>The mean age in the study population was 9.37 ± 3.57 years, with 56.45% males. The mean QOL scores in cognitive, emotional, social, and physical domains were 59.41, 55.11, 56.40, and 65.11, respectively. QOL steadily declined with age, with emotional and social domains more impacted on older children. Maternal illiteracy, low socioeconomic status, and earlier onset of epilepsy were significantly associated with poorer QOL (p<0.001). Only 21.25% of parents had complete awareness of SAP, and the children of these parents had relatively better QOL scores.</p><p><strong>Conclusion: </strong>QOL was better in CWE who were younger, had late-onset epilepsy, belonged to the upper socioeconomic class, and whose mothers were educated. Interventions enhancing parental awareness about SAP may lead to improvement in the QOL of CWE.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"225-234"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Lacunar Stroke in a Patient with Possible Normal Pressure Hydrocephalus (NPH).","authors":"Oluwatowo Daniel Fabiyi, Samuel Busayo Ogunlade","doi":"10.71480/nmj-v66i1.502","DOIUrl":"https://doi.org/10.71480/nmj-v66i1.502","url":null,"abstract":"<p><strong>Background: </strong>Normal pressure hydrocephalus (NPH) is a condition seen in the elderly, characterized by gait disturbances, urinary incontinence, and cognitive impairment. However, sudden onset neurological deficits suggest a vascular event rather than NPH.</p><p><strong>Methodology: </strong>We report a case of a 65-year-old male who presented with sudden onset gait difficulty and speech impairment, initially suspected to be idiopathic NPH. The diagnostic process and management strategies are discussed.</p><p><strong>Results: </strong>The patient's symptoms, including insidious gait difficulties, speech impairment, and memory loss, led to a suspected diagnosis of NPH. However, the sudden improvement of neurological deficits indicated a vascular cause. Computed Tomography (CT) imaging identified supporting evidence of a lacunar stroke, leading to a revised diagnosis.</p><p><strong>Conclusion: </strong>This case highlights the importance of considering vascular events in the differential diagnosis of NPH, especially when sudden neurological deficits improve rapidly. Early identification and differentiation between NPH and vascular events are crucial for appropriate management, particularly in low-resource settings.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"364-369"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and awareness of dental professionals regarding Professional Indemnity Insurance (PII) in India- A systematic review.","authors":"Ramandeep Singh Gambhir, Ridhi Aggarwal, Amit Aggarwal, Anurag Aggarwal, Nitin Kaushal, Ramandeep Kaur","doi":"10.71480/nmj.v66i1.588","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.588","url":null,"abstract":"<p><strong>Background: </strong>In recent times, patients have become more aware of their rights, and this has led to significant rise in the compensation cases against doctors. Due to the nature of the work and costs involved in the treatment, dental professionals are at high risk of facing such medical negligence cases. Therefore, the present study was conducted to assess knowledge and awareness regarding professional indemnity insurance (PII) among dental professionals in India.</p><p><strong>Methodology: </strong>A systematic review of relevant cross-sectional observational studies was conducted among dental professionals in India to report their knowledge and awareness regarding PII. Eight studies out of 98 were finally included in the review after conducting both electronic and manual search of scientific databases and making necessary exclusions. Potential biases were addressed and relevant data regarding PII data was extracted by the investigators concerned.</p><p><strong>Results: </strong>More than 60% of subjects had knowledge regarding PII in one of the study reports. Only 0.5% of subjects had taken PII in one of the studies and merely 8% in the other study. One of the studies mentioned that 76.2% of subjects paid compensation to their patients for negligence during dental treatment. Main hurdles for not opting PII were unawareness and considering PII non-mandatory for dentists. More than 90% of subjects in one study showed interest in buying PII for themselves.</p><p><strong>Conclusion: </strong>The results of the present review reveal that less than half of the subjects in some studies reported a lack of knowledge regarding PII and very few had taken PII. Therefore, there is an urgent need to make dental professionals aware of the benefits of obtaining PII to safeguard themselves from various litigation issues.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous subgaleal haematoma with severe headache in two children during acute painful sickle cell crisis.","authors":"Francis Akor, Toby Thenat, Sajjad Hussain, Suresh Kumar","doi":"10.71480/nmj.v66i1.615","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.615","url":null,"abstract":"<p><p>Sickle cell disease is an inherited disorder of haemoglobin formation, predominantly affecting individuals of African, Indian, or Mediterranean descent. Acute painful episodes frequently occur in these patients due to the blockage of small blood vessels by sickled cells, leading to tissue infarction. Two children of Nigerian descent, presented with severe headaches during a painful crisis episode with associated swelling on their scalps. CT imaging in both cases showed subgaleal haematoma which was managed conservatively in addition to managing the painful crisis with a good outcome. This report highlights the clinical presentation, diagnostic approach, and management of this uncommon complication of sickle cell anaemia.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"379-384"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Call to Action: Insights into Hypertension Prevalence and Management in an Urban Sub-Saharan African Population.","authors":"Teko Blaise Mbah, Bernadette Sandrine Lema, Armand Boris Rikam, Jacques Merci Baning Baning, Serge's Bruno Ngon, Georgette Merveille Kilama, Divine GoufanA Ngon, Odile Israelle Meto A Ngon, Fabrice Peguy Thome Ebango, Suzanne Adolphine Soppi Ebango, Emmanuel Eroume A Egom","doi":"10.71480/nmj.v66i1.712","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.712","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a global health challenge, with a disproportionate burden in low- and middle-income countries like Cameroon. Urban centers, such as Yaoundé, face increasing prevalence driven by rapid urbanization and healthcare disparities. The study objective is to assess hypertension prevalence, associated risk factors, and barriers to effective management in an urban Cameroonian population.</p><p><strong>Methodology: </strong>A cross-sectional study was conducted in 2024 as part of the HEAVEN-CIEL Hypertension Awareness Campaign. Data from 181 adults were collected through structured questionnaires and physical assessments, including blood pressure measurements. Associations with demographic, socioeconomic, and lifestyle factors were analyzed using chi-square tests and logistic regression.</p><p><strong>Results: </strong>Hypertension prevalence was 59.67%, with rates peaking at 75.56% among individuals aged 46-60 years (p = 0.0019). Medium-income participants showed the highest prevalence at 75.56% (p = 0.043). Obesity (p = 0.0024) and high-fat diets (p = 0.0212) were significant risk factors. Alarmingly, 87.04% of hypertensive individuals were untreated, highlighting gaps in medication access and adherence.</p><p><strong>Conclusion: </strong>Hypertension in Yaoundé represents a major public health concern, driven by age, socioeconomic disparities, and unhealthy lifestyle factors. The low treatment rates reflect systemic healthcare barriers. Comprehensive, culturally sensitive interventions are urgently needed to improve awareness, prevention, and management. Future research should focus on the longitudinal impacts of targeted public health strategies.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"290-302"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotional and Behavioural Problems of HIV-infected Children: Findings from a Southeastern Nigeria Tertiary Healthcare Facility.","authors":"Ikechukwu Frank Ogbonna, Nwaonu Chijioke Nwakanma, Joseph Ezeogu, Kelechi Kenneth Odinaka","doi":"10.71480/nmj.v66i1.639","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.639","url":null,"abstract":"<p><strong>Background: </strong>In children, HIV infection presents with grave consequences, including a predisposition to emotional and behavioural problems (EBP). These are mental health problems affecting thoughts, emotions, behaviours and relationships, and may be categorised into emotional problems (EP) and behavioural problems (BP). Studies have shown a high burden of EBP in children; however, knowledge gaps still exist regarding the burden of EBP on HIV-infected children. Our study seeks to address these gaps by determining the prevalence and type of EBP among HIV-infected children.</p><p><strong>Methodology: </strong>This cross-sectional and comparative study enrolled 386 participants (193 subjects and 193 controls). The subjects were HIV-infected children aged 2-15 years attending the Paediatric HIV Clinic of Federal Medical Centre, Umuahia. The controls were age and sex-matched HIV-negative children attending primary or secondary schools in Umuahia. Sociodemographic characteristics were assessed, and EBP was determined using the strengths and difficulties questionnaire.</p><p><strong>Results: </strong>Sixty-one subjects (31.6%) had EBP compared to 15 controls (7.8%) and this difference was significant (<i>p</i><0.001). The subjects were three times more likely to have EBP than the controls (aOR=3.03; CI=1.17-7.82). The EBP type showed that, while there was no significant difference in the multivariate analysis of the behavioural problems, emotional problems were significantly higher in the subjects than in the controls (<i>p</i> = 0.001). The subjects were six times more likely to have emotional problems than the controls (aOR=6.26; CI=2.80-13.97).</p><p><strong>Conclusion: </strong>There is a high burden of EBP among HIV-infected children in Umuahia with emotional problems as the common type.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"117-126"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Maternal Diseases and Placental Morphology among Parturient's in Port Harcourt, River State: A Multi-Centre Study.","authors":"Alerechi Emeka-Ogbugo, Simeon Chijioke Amadi, Jane Dumle Gbobie, Abbey Mkpe, Paul Ledee Kua, Ada Nkemagu Okocha, Oluwagbemiga Adewale","doi":"10.71480/nmj.v66i1.571","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.571","url":null,"abstract":"<p><strong>Background: </strong>Maternal diseases that complicate pregnancies such as Pregnancy induced hypertension (PIH) or Gestational Diabetes Mellitus (GDM) etc are markedly impressed on the placenta microscopically and macroscopically resulting in in defective placental development and perinatal morbidity and mortality. This study aimed to study the gross anatomy of the placenta and its relationship with maternal medical illnesses.</p><p><strong>Methodology: </strong>This study was a multi-centre hospital-based prospective cross-sectional study of 250 parturient who had term deliveries in Port Harcourt. The socio-demographic data and the medical history of the parturient were collected using a proforma. The placenta was collected after delivery and examined, and the morphometric features were noted. Data analysis was done with SPSS IBM version 23. Correlation and Regression analysis were employed in investigating the relationship between maternal/neonatal characteristics and placental morphology. Statistical significance was at a p-level of less than 0.05.</p><p><strong>Results: </strong>The mean age of the women ± SD = 30.44±4.1years and the median parity was para-2. Gestational Hypertension was the most common medical condition among participants. There was a statistically significant association between the maternal medical conditions and the placental shape with a preponderance of the oval shape among the women with hypertensive disorders. There was also, a statistically significant association between maternal medical conditions in pregnancy and other placental measurements such as weight, number of cotyledons, diameter, thickness, and cord insertion.</p><p><strong>Conclusion: </strong>Maternal medical conditions in pregnancy was found to have significant macroscopic imprints on the placental morphology and these can help in the diagnosis and management of medical illnesses that complicate pregnancies in our environment. More research is needed to establish causation.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"70-81"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Prevalent Hypertension by Aortic versus Brachial Blood Pressure Criteria for - A Pulse Wave Analysis Based Study from Adults of a City of West India.","authors":"Jayesh D Solanki, Pearl K Sajan, Bansi J Trivedi, Param J Kakadia, Sunil J Panjwani, Krishnapriya Mohandas","doi":"10.71480/nmj.v66i1.616","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.616","url":null,"abstract":"<p><strong>Background: </strong>Disparities exist in aortic blood pressure (aBP) and brachial blood pressure (bBP) and between aortic (AH) versus brachial hypertension (BH). While the former is superior, it is studied scarcely. Pulse wave analysis (PWA) provides objective and simultaneous measurement of both blood pressures to determine AH and BH. Using PWA, we compared prevalent AH and BH in a sample adult population.</p><p><strong>Methodology: </strong>By oscillometric PWA (Mobilograph, IEM, Stolberg, Germany), 1187 participants with age >18 years were evaluated. Simultaneous aBP and bBP were recorded by standard PWA protocol and prevalence of AH and BH was estimated. Age and gender-based subgroups were compared for aortic versus brachial BP differences. Prevalence of Hypertension, Isolated Systolic Hypertension, and Pulse Pressure ≥40 was compared between aortic versus brachial criteria.</p><p><strong>Results: </strong>Significant differences were seen between bBP and aBP across all age groups and in both genders, especially for the younger age groups. As compared to bBP, aBP gave a higher fetch for prevalent hypertension and a lower fetch for prevalent Isolated Systolic Hypertension (ISH). bPP ≥40 was sensitive but not specific as a surrogate for aPP ≥ 40.</p><p><strong>Conclusion: </strong>Across ages 18-65 in either sex, disparities exist between bBP and aBP mostly for SBP and PP with significant differences in prevalent Hypertension, Isolated Systemic Hypertension, and high pulse pressure. It reaffirms disparities of aBP and bBP and diagnosed brachial or central hypertension based on them with the need for further work.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"109-116"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and diagnostic dilemma of chromosomal abnormalities in the Niger Delta area of Nigeria; Is prenatal diagnosis worthwhile?","authors":"Mkpe Abbey, Boma Awoala West, Simeon Chijioke Amadi, Olufemi Adebari Oloyede, Faithwin Horsfall, Esther Ijeoma Nonye-Enyidah, Kenneth Eghuan Okagua, Ngozi Joseph Kwosah, Paul Ledee Kua, Rose Sitonma Iwo-Amah, Uduak Solomon Ocheche, Chidiebere Nwakanma Ononuju, Nimi Ngo Briggs, Basil Omiebi Altraide, Leesi Sapira-Ordu, Nestor Inimgba","doi":"10.71480/nmj.v66i1.561","DOIUrl":"https://doi.org/10.71480/nmj.v66i1.561","url":null,"abstract":"<p><strong>Background: </strong>Early detection of increasing numbers of cases of chromosomal abnormalities (aneuploides) at the Rivers State University Teaching Hospital (RSUTH) in the Niger Delta will enhance appropriate counseling of patients and early termination of the affected pregnancies. The study aimed to ascertain the prevalence of aneuploides at the RSUTH and to determine the necessity for early prenatal diagnosis in the Niger Delta.</p><p><strong>Methodology: </strong>This was a prospective cross-sectional study carried out over a three-year period (01/01/2018 - 01/01/2021) at the RSUTH, Nigeria. Newborn babies delivered at 28 weeks and above were assessed at birth for the phenotypes of aneuploidy and associated birth defects. A convenient sampling method was used to recruit all the babies with chromosomal abnormalities and their mothers. Data including that of socio-demographic, obstetric characteristics, and the fetuses were taken and analyzed using Statistical Package for Social Sciences Version 23 (SPSS version 23). Quantitative variables were summarized using means and standard deviation while qualitative variables were expressed as frequencies and proportions.</p><p><strong>Results: </strong>The total number of babies that were delivered by the 5868 participants in the study was 6078, out of which 10 cases of aneuploides were identified - 3 cases of trisomy 18 and 7 cases of Trisomy 21. The prevalence of chromosomal abnormalities at birth at the RSUTH was 0.165% of the total births, 1:2000 and 1:654 for T18 and T21 respectively. 1:654 mothers had babies with chromosomal abnormalities, 1:2000 and 1:833 for T18 and T21 respectively.Conclusion: The prevalence of chromosomal abnormalities at birth at the RSUTH of 0.165% represented a gross underestimation because the diagnosis was based on the outward phenotypical appearance of the neonates and it was made not from babies delivered at 20 weeks and above as practiced in Europe and other countries, but from 28 weeks. Prenatal diagnosis was therefore highly recommended in the Niger Delta.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 1","pages":"60-69"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}