Nigerian medical journal : journal of the Nigeria Medical Association最新文献

{"title":"Challenges, Clinical and Laboratory Profile of Children Referred for Micropenis at a Nigerian Tertiary Hospital.","authors":"Elizabeth Eberechi Oyenusi, Khadijah Omobusola Oleolo-Ayodeji, Olaolu Aziza Moronkola, Adedoyin Simon Oyenusi, Abiola Olufunmilayo Oduwole","doi":"10.71480/nmj.v66i2.819","DOIUrl":"10.71480/nmj.v66i2.819","url":null,"abstract":"<p><strong>Background: </strong>Micropenis in a child may not only be related to cosmesis but raise the suspicion of a disorder of sex development or endocrine conditions requiring urgent attention. The study aims to describe the clinical and laboratory profile of children referred for micropenis over a six-year period at the Lagos University Teaching Hospital (LUTH) and highlight challenges encountered in management of these children.</p><p><strong>Methodology: </strong>This was a retrospective study. Case records of patients who were referred with complaints or diagnoses of \"micropenis\" from March 2018 to March 2024 were analysed. The Health Research and Ethics Committee of LUTH approved the study.</p><p><strong>Results: </strong>Eighty-three children were referred for micropenis. On review, the stretched penile length (SPL) in 16 children (mean [SD]age of 8.9± 3.42 years) was within reference ranges and they were excluded from further evaluations. The remaining 67 children with confirmed micropenis constituted 12.4% of 541 new paediatric endocrine cases. The median age (range) at presentation was 9(0.7-16) years. Boys within the peripubertal age group constituted the majority of the patients. Co-morbidities included obesity, Down Syndrome, sickle cell anaemia, and growth hormone deficiency. Challenges in management included unaffordability of laboratory tests as only 21 children (31.3%) performed the human chorionic gonadotrophin (hCG) stimulation, our local testing, more than half (68.6%) could not carry out any investigations and age-appropriate/ preparations of testosterone were unavailable for treatment.</p><p><strong>Conclusion: </strong>Micropenis constituted a sizeable proportion of the paediatric endocrine consultations in our setting. Accurate measurements are important to exclude unaffected children and prevent unnecessary expensive investigations. The National Health Insurance Services (NHIS) should be strengthened to enable patients to access necessary investigations and treatment related to micropenis. Licensing of age-appropriate drugs for treatment by relevant authorities is advocated.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 2","pages":"698-704"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Challenges with Neovascular Glaucoma-Patient Tailored Strategies and Outcomes.","authors":"Aparna Rao, Tapas Ranjan Padhi, Sanjib M Khan","doi":"10.71480/nmj.v66i2.586","DOIUrl":"10.71480/nmj.v66i2.586","url":null,"abstract":"<p><strong>Background: </strong>To report the outcomes of patient-tailored concurrent combined surgery for retinal ischemia and intraocular pressure (IOP) control in neovascular glaucoma (NVG) with or without cataract.</p><p><strong>Methodology: </strong>Patients with Ninety-seven (97) eyes with NVG seen between January 2022-September 2023 at a tertiary eye care centre were recruited for this study. Six (6) eyes (4 proliferative diabetic retinopathy and 2 retinal vein occlusions) that underwent concurrent retinal and glaucoma procedures with or without cataract surgery, were selected. Outcomes after surgery were judged based on the World Glaucoma Association guidelines on reporting glaucoma surgical trials, comprising functional and surgical parameters.</p><p><strong>Results: </strong>The IOP reduced by>50% from baseline in all 6 eyes, with one eye developing shallow AC by overstraining and 3 eyes developing transient self-resolving hyphema. Two eyes received additional bevacizumab (n=1) or ranibizumab (n=1) injections for persistent DME at 4 and 5 months after surgery. The final IOP was reduced in all eyes at the final follow-up of 6±1.2 months, with one eye requiring 2 medications for IOP control.</p><p><strong>Conclusion: </strong>The outcomes after concurrent retinal and glaucoma filtering surgery in NVG may be comparable to those of the traditional stepwise approach to management, provided these are offered on a case-by-case basis.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 2","pages":"449-456"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistochemical profiling of Bcl-2 and EGFR proteins in cervical carcinoma at a tertiary hospital in Ghana.","authors":"Babatunde Moses Duduyemi, Ebenezer Kojo Addae, Francis Opoku, Kweku Bedu-Addo","doi":"10.71480/nmj.v66i2.713","DOIUrl":"10.71480/nmj.v66i2.713","url":null,"abstract":"<p><strong>Background: </strong>Using Immunohistochemistry (IHC) to assess the expression of EGFR and Bcl-2, and their correlations with clinicopathological features in a cohort of cervical cancer cases.</p><p><strong>Methodology: </strong>A retrospective and descriptive study in Komfo Anokye Teaching Hospital (KATH) Kumasi, Ghana. Patients were women diagnosed with cervical cancer at KATH from January 2015 to December 2016. For inclusion, suitable archived formalin fixed paraffin-embedded (FFPE) cases with adequately preserved tissue blocks and available clinicopathological data were selected for Tissue Microarray (TMA), otherwise, the cases were excluded. One hundred and thirty-five out of 230 cervical cases met the inclusion criteria. IHC assesses EGFR and Bcl-2 expressions, correlating with clinicopathological features in cervical cancer cases, enhancing molecular-clinical insights in the Ghanaian context.</p><p><strong>Results: </strong>The mean age of the cases was 58.9 (SD ± 17.88). Predominantly, 96.3% of the cases were of the squamous cell carcinoma (SCC) subtype. The majority of the cases (49.63%) were grade III. EGFR and Bcl-2 were expressed in 35.2% and 25.7% of the cases, respectively. Neither EGFR nor Bcl-2 showed any significant correlation with age, subtype, and histological grade. Significant inverse correlation was, however, observed between EGFR and Bcl-2 expression (P<0.001).</p><p><strong>Conclusion: </strong>The age stratification shown in this study confirms earlier reports of late age at diagnosis, mostly observed in our setting, and therefore emphasizes the need for effective and population-wide screening programs to ensure early diagnosis. The significant inverse correlation between EGFR and Bcl-2, suggestively leans towards a possible role played by EGFR in downregulating Bcl-2.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 2","pages":"575-585"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sport injury prevention strategies and sporting behaviors of male professional footballers - A cross-sectional study.","authors":"Saturday Nicholas Oghumu, Emem Akpabio Ekom, Ruth Oluwafunmike Nicholas, Peter Agba Awhen, Eguagie Okhuahesuyi, Kayode Israel Oke, Chidozie Emmanuel Mbada","doi":"10.71480/nmj.v66i2.758","DOIUrl":"10.71480/nmj.v66i2.758","url":null,"abstract":"<p><strong>Background: </strong>Identifying how playing positions (PP) and playing years (PY) influence injury prevention strategies (IPS) and sporting behaviors (SB) of footballers may guide health professionals in developing targeted interventions to prevent sports injuries and enhance players' fitness. This study assessed the association of PP and PY with IPS and SB of male professional footballers.</p><p><strong>Methodology: </strong>A cross-sectional survey of 130 male footballers aged 18 to 35 years, from six professional teams in Calabar, Cross River, Nigeria. Data was collected on PP, PY, IPS, and SB using adapted questionnaires on IPS and SB. Data was summarised using frequencies and percentages. The Chi-square test was used to analyse the associations among variables at p < 0.05.</p><p><strong>Results: </strong>Respondents were 31.5% defenders, 32.3% midfielders, 31.5% forwards, and 4.6% goalkeepers. Among these respondents, 54.6% played for 1-5 years, 42.3% for 6-10 years, and 3.1% for 11-15 years. Injury prevention was important to 57.7%, 86.9% had used IPS, 26.9% had used FIFA 11+, and 23.8% had used general warm-up programmes. In SB, 40.0% of respondents looked forward to matches and training, and over 50% felt energetic, found sporting meaningful, behaved aggressively towards opponents, exhibited fair play, acted strong and rigorous, were oblivious of surroundings, felt inspired, and were happy when engrossed in sport. Significant associations (p<0.05) were found between SB and each of PP and PY. PP and PY were not significantly associated (p>0.05) with IPS.</p><p><strong>Conclusion: </strong>Although PP and PY influenced the SB of male professional footballers, they do not impact IPS. Usage of IPS was higher in FIFA 11+ than in other IPS. Defenders and forwards have a higher propensity of exhibiting aggressive behaviours towards opponents when liable to injury than midfielders, while the burden of a team having good results was highest among defenders and midfielders than in forwards and goalkeepers.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 2","pages":"621-636"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catastrophic Outcomes: Rapid Multi-Organ Failure from Paraquat Poisoning- A Case Report.","authors":"Priya Pradipbhai Mehta, Raghuveer Siddhardha Annam, Ila Natvarlal Hadiyel","doi":"10.71480/nmj.v66i2.730","DOIUrl":"10.71480/nmj.v66i2.730","url":null,"abstract":"<p><p>Paraquat dichloride, a potent herbicide widely used in agriculture, poses a severe health risk due to its high toxicity. Ingesting even small amounts can cause fatal multi-organ failure. We report a case of a 19-year-old male who ingested approximately 5 ml of 24% paraquat dichloride. He presented with stable vital signs, but initial laboratory results showed elevated urea (26mg/dL), creatinine (0.97 mg/dL), and hypokalemia (3.2 mEq/L). Despite interventions including gastric lavage, N-Acetyl cysteine, methylprednisolone, and supportive care, he developed severe metabolic acidosis (HCO³- 22.8 to 16.3 mEq/L), acute renal failure (creatinine 0.97 to 4.62 mg/dL, urea 26 to 99 mg/dL, serum potassium 3.2 to 2.62 mEq/L), and multi-organ dysfunction. The unavailability of hemoperfusion has impacted the outcome. The patient's rapid deterioration highlights paraquat's aggressive nature and underscores the necessity for better therapeutic strategies and regulatory measures to prevent such poisoning.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 2","pages":"811-817"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial susceptibility pattern of pharyngeal isolates of children seen in a tertiary facility in Sokoto over three years (2022-2024).","authors":"Khadijat O Isezuo, Jibril Abubakar, Yahaya Mohammed, Usman Muhammad Sani, Usman Muhammad Waziri, Bilkisu Ilah Garba, Asmau Adamu, Fatima Bello Jiya, Amina Ibrahim, Khadija Muhammad Dada, Umar Muhammad Ango","doi":"10.71480/nmj.v66i2.717","DOIUrl":"10.71480/nmj.v66i2.717","url":null,"abstract":"<p><strong>Background: </strong>Acute pharyngitis is an inflammation of the pharynx and surrounding soft tissues caused by viral, bacterial, or fungal infectious agents. Only bacterial and fungal infections require antimicrobial therapy. Over-use of antibiotics can lead to anti-microbial resistance which is concerning. Antimicrobial susceptibility patterns of causative organisms are necessary to guide appropriate treatment. The study aims to retrospectively assess from laboratory records, the antimicrobial susceptibility pattern of pharyngeal isolates amongst children aged below 15 years managed at Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.</p><p><strong>Methodology: </strong>This was a three (3)-year descriptive retrospective review, from January 2022 to December 2024. A convenience sampling technique was used. A review of positive isolates and susceptibility patterns, which were categorized as sensitive, intermediate, and resistant was done. Information was extracted and entered in a study proforma sheet. Data was analyzed using SPSS version 23. A p-value of 0.05 was taken as significant.</p><p><strong>Results: </strong>The total number of patients results reviewed was 305 comprising 160 males (52.5%) and 145 females. The majority 182 (59.7%) were below five (5) years and 109 (35.7%) had positive bacterial and fungal isolates including 50 (16.4%) Streptococcus pneumoniae, 17 (5.6%) Staphylococcus spp., 16 (5.2%) other Streptococcus spp., & 7 (2.3%) Pseudomonas spp. Sixteen (5.2%) had the fungal agent Candida isolated. Streptococcus pneumoniae demonstrated high sensitivity to ciprofloxacin (44%) followed by ceftriaxone (38%) and erythromycin (24%) likewise Staphylococcus spp but resistance to cefotaxime and amoxycillin-clavulanate. Other Streptococcus spp had high sensitivity to ceftriazone (37.5%) but also demonstrated resistance to ciprofloxacin (37.5%) and gentamicin (31.3%).</p><p><strong>Conclusion: </strong>Streptococcus pneumonia, Staphylococcus spp, and other Streptococcus spp were the commonest bacterial pharyngeal isolates and demonstrated mixed sensitivity and resistance to quinolones and cephalosporins antibiotics amongst others. More effort on antimicrobial stewardship is key.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 2","pages":"586-597"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modelling the Effect of Indoor Residual Spraying on Malaria Transmission in Nassarawa State, North-central Nigeria.","authors":"Auwal Garba Suleiman, Lateef Kareem, Charles Obi","doi":"10.71480/nmj.v66i2.672","DOIUrl":"10.71480/nmj.v66i2.672","url":null,"abstract":"<p><strong>Background: </strong>Indoor Residual Spraying (IRS) is one of the two major strategies recommended by the World Health Organization for malaria vector control. Between 2012 and 2013, IRS was piloted in two Local Government Areas (LGAs) of Nassarawa State, North-central Nigeria. Uncertainties remain as to whether the intervention led to a decrease in the rate of malaria transmission or not.</p><p><strong>Methodology: </strong>A simple SIRS model was used to generate a system of ordinary differential equations. The solutions of the model, obtained through Euler's method, were adapted to malaria surveillance data obtained from one of the interventions LGAs to estimate model parameters. The rate of malaria transmission, obtained from the intervention LGA, was compared with the one obtained from a carefully selected control LGA to ascertain the effect of IRS on malaria transmission, assuming other model parameters remained constant.</p><p><strong>Results: </strong>The results showed a good fit of surveillance data to the numerical solutions of the model. The estimated rate of malaria transmission in the intervention LGA was lower than the rate estimated in the non-intervention LGA, even though the difference was marginal (0.95 versus 1.05). Over two years, IRS activities reduced the rate of malaria transmission in the intervention LGA by 10%. The modest decrease was attributed to the way IRS was implemented and the uncertainties associated with using routine surveillance data in Nigeria.</p><p><strong>Conclusion: </strong>Future IRS interventions should consider the effect of spray frequency on disease transmission and adopt a robust data collection strategy that will support proper monitoring and evaluation.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 2","pages":"528-539"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perception of nurse academicians on academic publications: A cross-sectional study.","authors":"Latha T, Suresh Kumar Sharma, Vipin Patidar, Rakhi Gaur, Santanu Nath, Shiv Kumar Mudgal","doi":"10.71480/nmj.v66i2.806","DOIUrl":"10.71480/nmj.v66i2.806","url":null,"abstract":"<p><strong>Background: </strong>Academic publication is a cornerstone of advancing nursing science, as it provides evidence-based research that guides clinical practice and education. However, the pressure to publish for career advancement has led to concerns about behaviours such as the 'urge to publish' and 'panic publishing'. The perception behind these trends remains unclear. This study aimed to assess the perception of Indian nurse academicians on academic publications.</p><p><strong>Methodology: </strong>This cross-sectional study surveyed Indian nurse academicians from Institutes of National Importance (INIs) of India who were selected convenient sampling technique. Data was collected through an online self-structured questionnaire. The survey covered socio-demographic details and perceptions for publishing in academic publications. Data analysis was performed using SPSS Version 26.0, with descriptive and inferential statistics. A significance level (p < 0.05) was used for statistical associations.</p><p><strong>Results: </strong>Of the respondents, 66.8% were female, and 92.3% had published before [median 12 (IQR 7-38) articles], with 21.7% preferring PubMed-indexed journals. More than two-thirds of participants (64.7%) spent an excessive amount of time on the publication process. There were differences by gender as men were more prone to assess publication metrics (p<0.05), ignore other facets of life for publishing (p=0.005), and self-reported publication addiction-like behaviors (18% compared to 4% for women).</p><p><strong>Conclusion: </strong>Academic publishing is a crucial but stress-inducing aspect of nurse academicians' careers. These findings underscore the need for a balanced approach that values quality over quantity in academic publishing. Institutions should promote ethical research practices, provide support to manage publication pressures and foster a more sustainable academic environment.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 2","pages":"681-691"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant Cystic Mucinous Borderline Tumour of the Ovary in a Young Female: A Rare Case Report.","authors":"Neelam Gupta, Deychen Myes, Kavya Avd, Sheetal Sharma","doi":"10.71480/nmj.v66i2.725","DOIUrl":"10.71480/nmj.v66i2.725","url":null,"abstract":"<p><p>Giant mucinous borderline tumours of the ovary are an unusual finding and pose a diagnostic challenge. We present a case of a 20-year-old unmarried, nulliparous female who presented with left quadrant pain and a progressively increasing abdomino-pelvic mass. Based on clinical and radiological investigations, a provisional diagnosis of mass arising from the ovary was made. The histopathological evaluation revealed it to be a mucinous borderline ovarian tumour.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 2","pages":"834-840"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High burden of chronic kidney disease of unknown cause among patients receiving renal replacement therapy in Northeast Nigeria: A cross-sectional survey of haemodialysis units.","authors":"Baba Waru Goni, Hamidu Suleiman Kwairanga Hamidu, Aliyu Abdu, Ibrahim Ummate, Alhaji Abdu, Ahmed Ibrahim Ba'aba, Mohammad Maina Sulaiman, Loskurima Umar, Muhammad Lawan Gana, Aliyu Abdulkadir, Sabiu Musa, Shatuwa Adamu, Idris A Usman, Hauwa Sabo Alhaji, Abubakar Idris Musa, Hamza Bukar Adam, Alhaji Umar Ismail, Ayabaryu Papka, Modu Mustapha, Saad Yauba Mohammed, Amin Oomatia, Mahmoud Bukar Maina, Neil Pearce, Ben Caplin","doi":"10.71480/nmj.v66i2.687","DOIUrl":"10.71480/nmj.v66i2.687","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease (CKD) is emerging as a significant public health concern in northeastern Nigeria, particularly in states such as Yobe and Borno. Despite its increasing impact, there is a lack of data characterizing this public health issue. This study aims to explore the prevalence, spatial distribution, and risk factors for CKD among patients receiving haemodialysis (HD) in the region.</p><p><strong>Methodology: </strong>A cross-sectional survey of HD centres in Yobe, Borno, and Jigawa States of Nigeria was conducted. Questionnaire responses were obtained on demographic, social, and clinical data. Spatial analyses were conducted to determine the geographic distribution of the cases.</p><p><strong>Results: </strong>We identified 376 patients receiving HD services across 4 centres. Of these, 207 (55.1%) were male and the mean age was 46.56 ± 16.4. Most patients reside in urban areas (67.6%). The main pre-dialysis occupations included civil service (100 [26.6%]), agriculture (65 [17.3%]), and trading (58 [15.4%]). 'Hypertension' (195 [51.9%]) was the most common self-reported primary renal disease, followed by unknown causes (70 [18.6%]) and Diabetic Kidney Disease (30 [8%]). Regional analysis demonstrated a particularly high burden of disease in Bade and Jakusko Local Government Areas.</p><p><strong>Conclusion: </strong>Spatial analysis suggests the existence of a CKD hotspot geographically associated with communities along the River Yobe, raising the possibility of an important environmental cause of disease. This study also highlights the lack of access to adequate diagnosis and geographical clustering of CKD burden in this region. These findings further reinforce the need for population-representative studies to characterize the burden of CKD alongside strategic healthcare interventions and collaboration among stakeholders aimed at improving access to care.xs.</p>","PeriodicalId":94346,"journal":{"name":"Nigerian medical journal : journal of the Nigeria Medical Association","volume":"66 2","pages":"564-574"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12280289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}