Clinical Challenges with Neovascular Glaucoma-Patient Tailored Strategies and Outcomes.

Aparna Rao, Tapas Ranjan Padhi, Sanjib M Khan
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Abstract

Background: To report the outcomes of patient-tailored concurrent combined surgery for retinal ischemia and intraocular pressure (IOP) control in neovascular glaucoma (NVG) with or without cataract.

Methodology: Patients with Ninety-seven (97) eyes with NVG seen between January 2022-September 2023 at a tertiary eye care centre were recruited for this study. Six (6) eyes (4 proliferative diabetic retinopathy and 2 retinal vein occlusions) that underwent concurrent retinal and glaucoma procedures with or without cataract surgery, were selected. Outcomes after surgery were judged based on the World Glaucoma Association guidelines on reporting glaucoma surgical trials, comprising functional and surgical parameters.

Results: The IOP reduced by>50% from baseline in all 6 eyes, with one eye developing shallow AC by overstraining and 3 eyes developing transient self-resolving hyphema. Two eyes received additional bevacizumab (n=1) or ranibizumab (n=1) injections for persistent DME at 4 and 5 months after surgery. The final IOP was reduced in all eyes at the final follow-up of 6±1.2 months, with one eye requiring 2 medications for IOP control.

Conclusion: The outcomes after concurrent retinal and glaucoma filtering surgery in NVG may be comparable to those of the traditional stepwise approach to management, provided these are offered on a case-by-case basis.

Abstract Image

Abstract Image

新血管性青光眼患者定制策略和结果的临床挑战。
背景:报道针对伴有或不伴有白内障的新生血管性青光眼(NVG)患者的视网膜缺血和眼压(IOP)控制的患者定制同步联合手术的结果。方法:本研究招募了2022年1月至2023年9月在三级眼科保健中心就诊的97(97)只眼NVG患者。选择6只眼(4只增殖性糖尿病视网膜病变和2只视网膜静脉闭塞)同时进行视网膜和青光眼手术,伴或不伴白内障手术。手术后的结果根据世界青光眼协会青光眼手术试验报告指南进行判断,包括功能和手术参数。结果:6只眼IOP均较基线降低50%,1只眼因过度劳损出现浅AC, 3只眼出现一过性自消性前房积血。2只眼睛在术后4个月和5个月接受额外的贝伐单抗(n=1)或雷尼单抗(n=1)注射以治疗持续性DME。最终随访6±1.2个月时,所有眼的最终IOP均降低,其中一只眼需要2种药物控制IOP。结论:NVG并发视网膜和青光眼滤过手术的结果可能与传统的逐步治疗方法相当,只要这些方法是根据具体情况而定的。
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