灾难性后果:百草枯中毒导致的快速多器官衰竭1例报告。

Priya Pradipbhai Mehta, Raghuveer Siddhardha Annam, Ila Natvarlal Hadiyel
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引用次数: 0

摘要

二氯百草枯是一种广泛应用于农业的强效除草剂,其高毒性对人体健康构成严重威胁。即使摄入少量也会导致致命的多器官衰竭。我们报告一个19岁的男性谁摄入了大约5毫升24%百草枯二氯。患者表现出稳定的生命体征,但最初的实验室结果显示尿素升高(26mg/dL),肌酐升高(0.97 mg/dL),低钾血症(3.2 mEq/L)。尽管采取了洗胃、n -乙酰半胱氨酸、甲基强的松龙和支持治疗等干预措施,患者仍出现了严重的代谢性酸中毒(HCO3- 22.8 - 16.3 mEq/L)、急性肾功能衰竭(肌酐0.97 - 4.62 mg/dL、尿素26 - 99 mg/dL、血钾3.2 - 2.62 mEq/L)和多器官功能障碍。无法获得血液灌流影响了结果。患者病情的迅速恶化凸显了百草枯的侵袭性,并强调了采取更好的治疗策略和监管措施以防止此类中毒的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Catastrophic Outcomes: Rapid Multi-Organ Failure from Paraquat Poisoning- A Case Report.

Paraquat dichloride, a potent herbicide widely used in agriculture, poses a severe health risk due to its high toxicity. Ingesting even small amounts can cause fatal multi-organ failure. We report a case of a 19-year-old male who ingested approximately 5 ml of 24% paraquat dichloride. He presented with stable vital signs, but initial laboratory results showed elevated urea (26mg/dL), creatinine (0.97 mg/dL), and hypokalemia (3.2 mEq/L). Despite interventions including gastric lavage, N-Acetyl cysteine, methylprednisolone, and supportive care, he developed severe metabolic acidosis (HCO3- 22.8 to 16.3 mEq/L), acute renal failure (creatinine 0.97 to 4.62 mg/dL, urea 26 to 99 mg/dL, serum potassium 3.2 to 2.62 mEq/L), and multi-organ dysfunction. The unavailability of hemoperfusion has impacted the outcome. The patient's rapid deterioration highlights paraquat's aggressive nature and underscores the necessity for better therapeutic strategies and regulatory measures to prevent such poisoning.

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