Frontiers in oral health最新文献

{"title":"Validation of a Hebrew version of the Early Childhood Oral Health Impact Scale.","authors":"Ofir Gaon, Lena Natapov, Diana Ram, Shlomo Paul Zusman, Avia Fux-Noy","doi":"10.3389/froh.2025.1543327","DOIUrl":"10.3389/froh.2025.1543327","url":null,"abstract":"<p><strong>Background: </strong>Dental problems such as early childhood caries in toddlers and children can significantly impact their and their family's oral health-related quality of life.</p><p><strong>Aim: </strong>This study aimed to validate a Hebrew version of the Early Childhood Oral Health Impact Scale (ECOHIS), providing a reliable tool for assessing oral health-related quality of life in toddlers and preschool children.</p><p><strong>Design: </strong>The ECOHIS questionnaire was translated from English to Hebrew using the \"forward-backward translation\" method. Two pediatric dentistry specialists evaluated the face and content validity of the Hebrew ECOHIS. Parents of children under 6 years old visiting the pediatric dentistry department at a medical center completed the Hebrew version of the ECOHIS questionnaire and provided their child's personal information. The decayed, missing, and filled teeth (dmft) index was extracted from the dental record.</p><p><strong>Results: </strong>The study group consisted of 96 children, whose parents participated, including 50 boys and 46 girls, with a mean age of 3.6 years. A positive correlation was found between higher ECOHIS scores and higher dmft indices. No differences were observed between ECOHIS scores and variables such as gender, age, and social subgroups of the participants. The overall scale reliability was high (Cronbach's alpha = .83). Confirmatory factor analysis supported the questionnaire's two-factor structure and indicated a moderate fit to the data.</p><p><strong>Conclusion: </strong>The Hebrew version of the ECOHIS was found to be valid and reliable for measuring oral health-related quality of life in toddlers and preschool children in Israel.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1543327"},"PeriodicalIF":3.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12089046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of hyaluronic acid in the treatment of peri-implant diseases: results of a meta-analysis.","authors":"Nansi López-Valverde, Antonio López-Valverde, José Antonio Blanco Rueda","doi":"10.3389/froh.2025.1564599","DOIUrl":"https://doi.org/10.3389/froh.2025.1564599","url":null,"abstract":"<p><p>Peri-implantitis is an infectious-inflammatory disease that affects the tissues surrounding implants and is one of the main causes of implant failure. Hyaluronic acid (HA) is a natural polymer with multiple biomedical and cosmetic applications. The aim of this systematic review and meta-analysis was to evaluate its efficacy in the treatment of peri-implant disease.</p><p><strong>Methods: </strong>In accordance with PRISMA, the question was established: is HA treatment effective as a sole or adjunctive therapy for the treatment of peri-implantitis? PubMed/Medline, Embase, Cochrane Central, Dentistry & Oral Sciences Source and Web of Science were searched until December 2024. Inclusion criteria were interventional studies (RCTs and case series), according to the PICOs strategy in subjects with peri-implant pathology (participants), treated with HA (intervention) compared to conventionally treated or untreated patients (control) and assessing response to treatment (outcomes).</p><p><strong>Results: </strong>Thirty-two studies were obtained and four were selected. Risk of bias was assessed using the Cochrane Risk of Bias tool and methodological quality using the Joanna Briggs Institute tool. Meta-analysis of parameters was performed for pooled studies and for subgroups. The overall effect was in favour of the experimental group.</p><p><strong>Conclusions: </strong>The use of HA as background or adjunctive therapy in peri-implantitis may be effective, although well-designed RCTs are warranted to validate the efficacy of the product.</p><p><strong>Systematic review registration: </strong>Identifier (INPLANSY 2024100050).</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1564599"},"PeriodicalIF":3.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of uniquely tumorigenic cancer stem cells in salivary gland adenoid cystic carcinoma.","authors":"Kristy A Warner, Sosuke Sahara, Alexandra E Herzog, Felipe Nör, Rogerio M Castilho, Peter J Polverini, Jacques E Nör","doi":"10.3389/froh.2025.1570042","DOIUrl":"https://doi.org/10.3389/froh.2025.1570042","url":null,"abstract":"<p><strong>Background: </strong>Cancer stem cells (CSC) are endowed with multipotency, self-renewal and unique tumorigenic potential. They have been identified as cells with high activity of aldehyde dehydrogenase (ALDH) and high expression of CD44 in head and neck squamous cell carcinoma (HNSCC). The objective of this work is to understand whether salivary gland adenoid cystic carcinoma contain CSCs and whether they exhibit a unique tumorigenic activity in this cancer.</p><p><strong>Methods: </strong>We used flow cytometry, salisphere and western blot assays with 3 human ACC cell lines (UM-HACC-2A, UM-HACC-14, UM-HACC-6) to characterize the impact of ALDH activity and CD44 expression. <i>In vitro</i> results were verified <i>in vivo</i> by orthotopic injection of cells retrieved from a patient-derived xenograft (PDX) model of ACC (UM-PDX-HACC-14) in the submandibular gland of SCID mice. Primary tumor and metastatic spread were evaluated by 2 pathologists blinded for experimental conditions.</p><p><strong>Results: </strong>The fraction of ALDH^highCD44^high cells in UM-HACC-2A, UM-HACC-14 and UM-HACC-6 ranged from 3% to 8%. ALDH^highCD44^high cells formed more salispheres and expressed higher levels of stem cell markers (e.g., Notch2, Bmi-1) compared to control ALDH^lowCD44^low cells. ALDH^highCD44^high cells sorted from the ACC PDX tumors were more tumorigenic upon orthotopic transplantation into submandibular salivary glands and generated more lung metastases than control ACC cells. Strong ALDH1A1 staining was observed in the majority of salivary gland tumors and lung metastases generated by transplantation of ALDH^highCD44^high cells.</p><p><strong>Conclusions: </strong>We conclude that salivary gland adenoid cystic carcinoma contain a small population of uniquely tumorigenic cells characterized by high ALDH activity and expression.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1570042"},"PeriodicalIF":3.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Access to adolescent-responsive oral, mental, sexual, and reproductive healthcare services in Africa through dental clinics.","authors":"Nadia Adjoa Sam-Agudu, Chinye Osa-Afiana, Maha El Tantawi, Moréniké Oluwátóyìn Foláyan","doi":"10.3389/froh.2025.1545988","DOIUrl":"https://doi.org/10.3389/froh.2025.1545988","url":null,"abstract":"<p><p>In many healthcare systems, oral healthcare is provided separately from other clinical services. For 10-19-year-old adolescents in particular, this separation of care perpetuates the underutilization of oral health services and the neglect of oral health. Available evidence indicates that there are interconnections between oral, mental, sexual, and reproductive health (OMSRH) in adolescents. For African countries, there are opportunities to draw on lessons learned from HIV-centered models of integrated care to develop and evaluate dental clinic-centered models for integrating adolescent OMSRH services. This article makes a case for evidence-based adolescent OMSRH service integration in African countries. Integration is expected to align with the principles of sustainable development goals, universal healthcare, and the World Health Organization's calls for adolescent-responsive health services. We present a conceptual framework and propose an implementation science-guided blueprint for the integration of adolescent OMSRH care. The focus on dental clinics for integration can potentially increase access to, and use of oral healthcare while addressing adolescents' mental, sexual and reproductive health needs. OMSRH integration for adolescents in African settings will require intensive engagement of adolescents and other crucial stakeholders. Further exploratory and implementation research is also needed to design and evaluate OMSRH integration models to establish best practices for long-term impact on adolescent health outcomes.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1545988"},"PeriodicalIF":3.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Unravelling the role of the oral microbiome in cancer.","authors":"Julia S Bruno, Ghanyah Al-Qadami, Divya Gopinath, Alexa M G A Laheij","doi":"10.3389/froh.2025.1606144","DOIUrl":"10.3389/froh.2025.1606144","url":null,"abstract":"","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1606144"},"PeriodicalIF":3.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between sexual identity and caries risk indicators among adolescents and adults in Nigeria: implications for policy and actions.","authors":"Morenike Oluwatoyin Folayan, Olakunle Oginni, Olanrewaju Ibigbami, Abiola Adeniyi, Joanne Lusher","doi":"10.3389/froh.2025.1551013","DOIUrl":"10.3389/froh.2025.1551013","url":null,"abstract":"<p><strong>Background: </strong>There is little known about the oral health profile of sexual minority individuals in Africa. The study aimed to investigate the association between sexual identity and dental caries risk behaviors of adolescents and adults in Nigeria.</p><p><strong>Methods: </strong>This was a secondary analysis of data collected from participants aged 13 years and above recruited using an online electronic survey between 16th September and 31st October 2020. The dependent variable was dental caries risk behaviour (daily tooth brushing twice a day or more, daily consumption of refined carbohydrates in-between-meals thrice a day or more, history of dental service utilisation, and poor knowledge of dental caries prevention). The independent variable was sexual identity (heterosexual and sexual minority individuals). Four multivariate regression models were developed to assess the associations between sexual identity and each of the dependent variables. Each model was adjusted for age, sex, educational level, employment status, and marital status.</p><p><strong>Results: </strong>The data of 2,772 respondents were extracted for analysis. Sexual minority individuals had significantly lower odds of consuming refined carbohydrates in-between-meals three times daily or more (AOR: 0.53; 95% CI: 0.43-0.64; <i>p</i> < 0.001), tooth brushing twice daily or more (AOR: 0.82; 95% CI: 0.68-0.99; <i>p</i> = 0.037), and making use of a dental service within the last year before the survey (AOR: 0.66; 95% CI: 0.55-0.79; <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>While sexual minority individuals in Nigeria exhibit some protective behaviors (lower sugar intake), their reduced dental care utilization and brushing frequency signal a need for inclusive, equity-focused oral health policies. Further research is needed to provide evidence for the development of a comprehensive oral healthcare programme that addresses the needs of the sexual minority population.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1551013"},"PeriodicalIF":3.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring parental opinions on oral hygiene behavior and knowledge of their young children in Lithuania: a cross-sectional survey study.","authors":"Yvonne A B Buunk-Werkhoven, Rasa Tamulienė, Daiva Mačiulienė","doi":"10.3389/froh.2025.1530265","DOIUrl":"10.3389/froh.2025.1530265","url":null,"abstract":"<p><strong>Background: </strong>An appropriately formulated oral health education program carefully based on research, can increase knowledge, change behavior in a positive direction and improve self-confidence. This study aimed to examine parental opinions on their children's oral hygiene behavior (OHB) and oral health knowledge (OHK) among their pre- and primary school children in Kaunas, Lithuania.</p><p><strong>Methods: </strong>In this cross-sectional study, an online 33-question survey was conducted before and after World Oral Health Day on March 20 to assess the oral hygiene skills, eating habits, and demographics of their 5-12 year children. A total of 532 parents participated, with data from 420 parents, mainly married mothers (average age 37.3 years) being analyzed. Most participants had higher education, lived in Kaunas, and had one to three children, with an average age of 7 years for the oldest child.</p><p><strong>Results: </strong>Most participants used a manual toothbrush. The adapted OHB index showed that most parents generally had good control over their children's tooth brushing habits, with many brushing twice daily and using fluoride toothpaste. One-third of parents always re-brushed their child's teeth after the child brushed independently. Parents demonstrated strong knowledge of their children's oral health care, as reflected in high scores on the adapted OHK index. A positive correlation was found between OHB and OHK (<i>r</i> = 0.14, <i>p</i> = 0.05). Younger children were re-brushed more frequently, and higher parental OHK was linked to more frequent re-brushing, particularly for children less than 10 years, and parents with higher education had better OHK but did not demonstrate better OHB.</p><p><strong>Conclusions: </strong>The insights gained from parents into their children's OHB and OHK can help implement an evidence-based preventive approach to improve their children's oral hygiene practices.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1530265"},"PeriodicalIF":3.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence-driven clinical decision support systems for early detection and precision therapy in oral cancer: a mini review.","authors":"Manoj Kumar Karuppan Perumal, Remya Rajan Renuka, Suresh Kumar Subbiah, Prabhu Manickam Natarajan","doi":"10.3389/froh.2025.1592428","DOIUrl":"https://doi.org/10.3389/froh.2025.1592428","url":null,"abstract":"<p><p>Oral cancer (OC) is a significant global health burden, with life-saving improvements in survival and outcomes being dependent on early diagnosis and precise treatment planning. However, diagnosis and treatment planning are predicated on the synthesis of complicated information derived from clinical assessment, imaging, histopathology and patient histories. Artificial intelligence-based clinical decision support systems (AI-CDSS) provides a viable solution that can be implemented via advanced methodologies for data analysis, and synthesis for better diagnostic and prognostic evaluation. This review presents AI-CDSS as a promising solution through advanced methodologies for comprehensive data analysis. In addition, it examines current implementations of AI-CDSS that facilitate early OC detection, precise staging, and personalized treatment planning by processing multimodal patient information through machine learning, computer vision, and natural language processing. These systems effectively interpret clinical results, identify critical disease patterns (including clinical stage, site, tumor dimensions, histopathologic grading, and molecular profiles), and construct comprehensive patient profiles. This comprehensive AI-CDSS approach allows for early cancer detection, a reduction in diagnostic delays and improved intervention outcomes. Moreover, the AI-CDSS also optimizes treatment plans on the basis of unique patient parameters, tumor stages and risk factors, providing personalized therapy.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1592428"},"PeriodicalIF":3.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12066789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D receptor gene polymorphism in oral cancer as a function of tobacco consumption: an evidence based systematic review and meta-analysis.","authors":"Tribikram Debata, Amrita Swain, Soumya Ranjan Jena, Surya Narayan Das, Niranjan Mishra, Luna Samanta","doi":"10.3389/froh.2025.1550683","DOIUrl":"https://doi.org/10.3389/froh.2025.1550683","url":null,"abstract":"<p><strong>Background: </strong>The association between Vitamin D Receptor (VDR) polymorphisms and different cancers has attracted growing attention; nonetheless, the function of these genetic variants in tobacco-related oral cancer remains little comprehended. This review assesses and integrates research concerning the influence of VDR gene variants on the development of tobacco-related oral cancer, emphasizing genetic underpinnings of individual vulnerability and possible tailored preventative approaches.</p><p><strong>Materials and methods: </strong>The search strategy for this systematic review and meta-analysis was devised to comprehensively identify relevant studies from diverse sources. The investigation included three primary components: the VDR gene, oral cancer, and tobacco. The data from the papers included in the study were independently retrieved by two reviewers. The incidence was evaluated as an odds ratio (OR) with 95% confidence interval (95% CI) using SPSS software.</p><p><strong>Results: </strong>A preliminary search of biomedical electronic research databases (PubMed, Web of Science, Scopus, Embase, and the Cochrane Library) yielded 60,345 papers. After multi-phase exclusions, five studies met the inclusion criteria. The meta-analysis highlights interactions between genetic polymorphisms, smoking, aging, and oral health risks. The CYP24A1 (rs2296241) heterozygote genotype significantly reduces oral cancer risk (OR = 0.281, <i>P</i> = 0.00001). Variants rs1544410 and rs2228570 influence oral health outcomes. The rs2239185 TT (OR = 2.68, <i>P</i> = 0.009) and rs7975232 CC (OR = 2.25, <i>P</i> = 0.026) increase oral lichen planus risk. Older age is significantly linked to OSCC risk (<i>P</i> = 0.001).</p><p><strong>Conclusion: </strong>This research underscores the role of VDR gene variants in tobacco-related oral cancer. Further studies are essential to validate findings and explore underlying mechanisms.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/PROSPERO/view/CRD42024587292, identifier: CRD42024587292.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1550683"},"PeriodicalIF":3.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12066760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A hybrid approach to predicting and classifying dental impaction: integrating regularized regression and XG boost methods.","authors":"Asok Mathew, Pradeep K Yadalam, Ahmed Radeideh, Shorouq Hadi, Rona Swed, Reyyan Cheema, Majd Mousa Al-Mohammad, Mohammed Alsaegh, S R Shetty","doi":"10.3389/froh.2025.1524206","DOIUrl":"10.3389/froh.2025.1524206","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Dental impaction is a significant clinical challenge that requires advanced predictive modeling and healthcare analytics approaches. Impaction, a tooth alignment issue, is diagnosed using radiographic measurements like panoramic radiographs and CBCT. Artificial Intelligence (AI) is improving the accuracy of predicting dental impaction. Advanced predictive models like logistic Regression and XGBoost analyze critical variables, identify patterns, and perform predictive analysis. These models can identify potential impactions, assess impaction type, and develop treatment plans. Integrating AI into radiographic assessments is expected to enhance further the precision and risk-minimizing capabilities of surgical planning in dentistry. This study presents a hybrid approach combining regularized regression and ensemble methods to enhance the classification and prediction of dental impaction outcomes. By leveraging machine learning and statistical learning techniques, we aim to develop a robust clinical decision support system for dental practitioners.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This research aims to predict the eruption of 3rd molars in the mandible by analyzing three parameters: the distance from the lower 2nd molar to the anterior border, the mesiodistal width of the third molar, and the distance from the apex of the root to the inferior border of the mandible. The study is quantitative, observational, and cross-sectional retrospective. The distance from the lower 2nd molar to the anterior border determines the importance of space available for eruption. The distance from the root apex to the lower border addresses natural eruptive forces and resistance during the eruption. The study aims to find a correlation between eruption and distance from the root apex to the lower border of the mandible. Our feature selection process utilizes ensemble learning algorithms integrated with regularized regression techniques to analyze various parameters. This data analysis framework combines multiple predictive modeling approaches to achieve optimal results.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The horizontal type of impaction has the lowest S/W ratio (0.9267), indicating the least available distal to 2nd molar space. This suggests a low potential for future eruptions. The regression equation calculates the S/W ratio using impacted molar width and distal space. A ratio greater than 1.1 indicates a good probability of lower 3rd molar eruption, while a below 0.8 indicates no eruption. The algorithm development process demonstrated the effectiveness of our hybrid approach in dental health analytics. The study improved impaction prediction accuracy to a rate of 78%, with horizontal class predictions achieving a precision of 0.72 and an error rate of 28.1%. Additionally, the regularized logistic regression model attained 75% accuracy for classification and prediction.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The study aims to improve dental r","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1524206"},"PeriodicalIF":3.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12066611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}