Frontiers in oral health最新文献

{"title":"Standardized coronectomy versus total extraction for impacted mandibular third molars: a single-blinded prospective analysis of patient-reported outcomes.","authors":"Mohamad Khalid Al-Ali, Roba Saqan, Sarah Alkhazraji, Kamis Gaballah","doi":"10.3389/froh.2025.1647852","DOIUrl":"10.3389/froh.2025.1647852","url":null,"abstract":"<p><strong>Introduction: </strong>Coronectomy is proposed as an alternative to surgical extraction for impacted mandibular third molars, particularly in cases with an elevated surgical risk of inferior alveolar nerve injury. However, this procedure is not widely adopted by many surgeons due to concerns about potential complications and the perception that patients may be less likely to accept this treatment option.</p><p><strong>Methods: </strong>This cross-sectional, prospective, single-blinded study compared patient-reported outcomes between standardized coronectomy and extraction of impacted mandibular third molars in 70 patients (aged 19-55 years) using the Postoperative Symptom Severity (PoSSe) scale.</p><p><strong>Results: </strong>While coronectomy avoided nerve injury, it resulted in relatively longer recovery times (40% vs. 28.6% requiring ≥5 days) and prolonged medication use (34.3% vs. 14.3% >5 days) compared to extraction. Coronectomy patients reported significantly higher pain and swelling scores, particularly among females (>25 years), though neither procedure adversely affected eating, speech, or quality of life. Gender and age influenced outcomes, with females and older patients experiencing more pronounced postoperative morbidity after coronectomy.</p><p><strong>Discussion: </strong>These findings underscore the need for demographic-specific counseling and tailored postoperative care when selecting coronectomy. Further research with larger sample sizes is recommended to validate these findings and optimize decision-making for mandibular third molar surgeries.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1647852"},"PeriodicalIF":3.1,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144983923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of oral metronomic chemotherapy in the management of head and neck squamous cell carcinoma-a systematic review.","authors":"Aardra Binithadas Segin Chandran, Deepak Pandiar, Reshma Poothakulath Krishnan, Divya Gopinath","doi":"10.3389/froh.2025.1632316","DOIUrl":"10.3389/froh.2025.1632316","url":null,"abstract":"<p><strong>Background: </strong>Head and neck squamous cell carcinoma (HNSCC) is a group of heterogeneous malignancies and constitutes one of the most prevalent forms of cancer. Oral metronomic chemotherapy (OMCT) is a treatment in which low doses of anticancer drugs are given at regular intervals over a long time, with many advantages over conventional therapies, particularly in nations with high cancer burden. The present systematic review aimed to evaluate the efficacy of OMCT in the management of HNSCC in comparison to other standard chemotherapy regimens. Methodology: The review was registered in the Prospero database (CRD42023426000). An electronic search was conducted using PubMed, Scopus, Web of Science and Google Scholar databases. Articles in which OMCT was used to treat HNSCC were included for systematic review, and the survival and response rates were analyzed.</p><p><strong>Results: </strong>Twenty-four eligible articles were included for evaluation, which revealed that administration of OMCT produced higher survival and response rates in subjects compared to standard chemotherapy.</p><p><strong>Conclusion: </strong>The evidence from the included studies supports that oral metronomic chemotherapy is substantially more effective as compared to standard chemotherapy regimens in squamous cell carcinomas of the head and neck.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/PROSPERO/view/CRD42023426000, identifier (CRD42023426000).</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1632316"},"PeriodicalIF":3.1,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12343508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144850090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phospho-tau 181 is enhanced in saliva and plasma of edentulous patients: a first sign of dementia?","authors":"Christine Zürcher, Michaela Defrancesco, Christian Humpel","doi":"10.3389/froh.2025.1627681","DOIUrl":"10.3389/froh.2025.1627681","url":null,"abstract":"<p><strong>Objectives: </strong>There is evidence that periodontitis can enhance the progression of Alzheimer's disease (AD). The biomarkers beta-amyloid (40 and 42), total tau, and phospho-tau181 (pTau181) in cerebrospinal fluid help to diagnose AD. Saliva is an easy-to-collect fluid and we aim to analyze these biomarkers in patients with periodontitis.</p><p><strong>Subjects and methods: </strong>Four groups of individuals were included: patients with healthy periodont, those with mild and severe periodontal diseases, and edentulous patients. These four biomarkers were analyzed in saliva using Lumipulse technology, and as a control, also cortisol, transferrin, and interleukin-6 were measured. Patients underwent a neuropsychological assessment, and plasma pTau181 was analyzed.</p><p><strong>Results: </strong>No changes were seen for salivary beta-amyloid and total tau; however, salivary pTau181 was significantly increased in edentulous patients. This was accompanied by enhanced plasma pTau181 levels.</p><p><strong>Conclusion: </strong>Our data show that pTau181 was significantly higher in saliva and plasma of edentulous patients, and we suggest that the loss of teeth may be linked to the progression of dementia. Consultation of dentists may be of importance to find risk factors for the progression of dementia, and salivary pTau181 could be a new associative marker.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1627681"},"PeriodicalIF":3.1,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12343693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144850091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scoping review of school-based oral health interventions among adolescents in Nigeria.","authors":"Abel Nnamdi Chukwuemeka, Richard Oveh, Anita Dabar, Omorinola Afolabi, Saheed Ademola Ibraheem, Folahanmi Tomiwa Akinsolu, Abideen Olurotimi Salako, Omolola Titilayo Alade, Foluso Owotade, George Uchenna Eleje, Oliver Ezechi, Joanne Lusher, Moréniké Oluwátóyìn Foláyan","doi":"10.3389/froh.2025.1577753","DOIUrl":"10.3389/froh.2025.1577753","url":null,"abstract":"<p><strong>Background: </strong>This scoping review aimed to map school-based oral health interventions for adolescents in Nigeria and to identify gaps that can be addressed to promote optimal oral health in the population.</p><p><strong>Methods: </strong>This scoping review is registered with the Open Science Framework (OSF) Registries (https://doi.org/10.17605/OSF.IO/CMRV4). An electronic search of PubMed, Scopus, Web of Science, African Journals Online, and Google Scholar for papers focused on oral health interventions implemented in schools in Nigeria, involving adolescents, and published in English between January 2000 and July 2024 was retrieved. Information extracted included study characteristics (author, year, study design), study population characteristics, type of interventions, focus, and key findings.</p><p><strong>Results: </strong>The search yielded 392 results, with five studies meeting the eligibility criteria. All studies focused on oral health education, and education was delivered verbally. Four studies assessed the effect of education on oral hygiene practices, three assessed the effect on the consumption of refined carbohydrates, two measured dental service utilization as an outcome, and one assessed smoking cessation. One study showed that peer- and teacher-led models demonstrated comparable effectiveness, making them viable in resource-limited settings.</p><p><strong>Conclusion: </strong>This scoping review found that school-based oral health interventions effectively improved oral hygiene among adolescent populations in Nigeria, though the few studies skewed to southern Nigeria make it difficult to generalize findings to Nigeria.</p><p><strong>Review registration: </strong>OSF, https://doi.org/10.17605/OSF.IO/CMRV4.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1577753"},"PeriodicalIF":3.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144839427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of transcriptomics in the study of oral cancer.","authors":"Prabhu Manickam Natarajan, Vidhya Rekha Umapathy","doi":"10.3389/froh.2025.1524364","DOIUrl":"10.3389/froh.2025.1524364","url":null,"abstract":"<p><p>Oral cancer, a formidable public health challenge, demands innovative approaches for early detection and effective treatment. This review explores the transformative role of transcriptomics in oral cancer research, leveraging cutting-edge technologies to decode the RNA landscape of tumors. We delve into RNA sequencing (RNA-seq), single-cell RNA sequencing (scRNA-seq), long non-coding RNA sequencing (lncRNA-seq), microarray analysis, and small RNA profiling, showcasing their unique contributions to unraveling the complexities of oral cancer. By mapping gene expression patterns, identifying biomarkers, and understanding tumor heterogeneity at an unprecedented resolution, transcriptomics offers powerful insights into the molecular mechanisms driving oral cancer. Furthermore, we highlight how these approaches pave the way for personalized medicine, enabling precise therapeutic interventions and innovative treatment strategies. The review also addresses the future directions and challenges in the field, emphasizing the need for advanced computational tools and interdisciplinary collaboration to fully harness the potential of transcriptomics in transforming oral cancer care.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1524364"},"PeriodicalIF":3.1,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salivary microbiota profile in adult and children population according to active dentin caries: a metagenomic preliminary analysis.","authors":"Nuria Tamayo-Estebaranz, Carolina Muñoz-González, Ana María Gil-Valcárcel, Paula Calvo López-Dávalos, Andrea Martín-Vacas, Marta M Paz-Cortés, Juan Manuel Aragoneses","doi":"10.3389/froh.2025.1599925","DOIUrl":"10.3389/froh.2025.1599925","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;The aim of this study was to investigate the relationship between active dentin caries (ADC), salivary biochemical parameters, and salivary microbiota composition in Spanish children and adults.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Saliva samples were collected from 80 subjects (40 adults and 40 children) divided between ADC and non-ADC. Salivary biochemical determination was performed by analysing total protein content (TPC) and total antioxidant activity (TAC) in saliva supernatants. DNA was obtained from the pellet of saliva samples using the Bacterial DNA kit and analysed with the Illumina NextSeq platform from all participants. Alpha diversity (Chao, Observed Features, Shannon and Simpson indices) and beta diversity (PCoA plot and PERMANOVA procedure) were analysed. In addition, Linear Discriminant Analysis Effect Size (LEfSe) was used to identify differential taxa between groups. All statistical analysis were performed with a 95% confidence level (&lt;i&gt;p&lt;/i&gt; &lt; 0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;No significant associations were found between ADC and salivary biochemical markers in either the adult or pediatric age group, suggesting that these parameters alone may not sufficiently reflect cariogenic activity. Microbiota analysis at the phylum level did not show significant correlations with ADC; however, distinct associations appeared at the genus and species levels. In adults, several genera (&lt;i&gt;Corynebacterium&lt;/i&gt;, &lt;i&gt;Porphyromonas&lt;/i&gt;, &lt;i&gt;Tannerella&lt;/i&gt;, &lt;i&gt;Catonella&lt;/i&gt;, &lt;i&gt;Filifactor&lt;/i&gt;, &lt;i&gt;Parvimonas&lt;/i&gt;, and &lt;i&gt;Dialister&lt;/i&gt;) were positively associated with ADC, reflecting a shift towards a dysbiotic microbiome composition that overlaps with periodontal and endodontic pathologies. Conversely, &lt;i&gt;Haemophilus&lt;/i&gt; was negatively correlated with ADC, potentially indicating a protective role. At the species level, a positive correlation with ADC was found with &lt;i&gt;Porphyromonas gingivalis&lt;/i&gt;, &lt;i&gt;Porphyromonas endodontalis, Peptostreptococcus stomatis&lt;/i&gt;, &lt;i&gt;Leptotrichia buccalis&lt;/i&gt;, &lt;i&gt;Prevotella oris&lt;/i&gt;, or &lt;i&gt;Corynebacterium matruchotii&lt;/i&gt; in the adult population. In children, microbial associations with caries were more limited, with &lt;i&gt;Scardovia&lt;/i&gt;, a well-known acidogenic genus, positively correlated with ADC, and &lt;i&gt;P. stomatis&lt;/i&gt; showing a negative association. Interestingly, &lt;i&gt;P. stomatis&lt;/i&gt; exhibited opposite correlations in adults and children, possibly reflecting age-specific ecological roles. No significant differences in alpha or beta diversity were found either in adults or children participants.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Overall, these findings highlight a stronger and more diverse association between salivary microbiota and caries in adults compared to children. These results underscore the importance of age-specific microbial signatures in the aetiology of dental caries. The obtained differences suggest that caries development in adults may involve broader dysbiosis involving ","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1599925"},"PeriodicalIF":3.1,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Membrane vesicles from Red Complex bacteria: key players in oral pathogenesis, immune disruption, systemic diseases, and therapeutic insights.","authors":"Venkatramanan Mahendrarajan, Huldah Pearlin Sarah Lazarus, Gothandam Kodiveri Muthukaliannan, Sheeja Varghese, Nalini Easwaran","doi":"10.3389/froh.2025.1607931","DOIUrl":"10.3389/froh.2025.1607931","url":null,"abstract":"<p><p>The oral cavity serves as a habitat for a diverse array of microorganisms, each performing distinct functions, thereby constituting a vibrant and intricate ecological community. The most common pathogenic bacteria in the oral ecosystem are the Red Complex group, which includes <i>Porphyromonas gingivalis</i>, <i>Treponema denticola</i>, and <i>Tannerella forsythia</i>. These bacteria have several ways to inflict damage, such as creating biofilms and secreting nano-sized vesicles from their outer membrane, called Outer Membrane Vesicles (OMV). OMVs are nano structures that carry proteins, lipids, and toxins from the outer membrane of Gram-negative bacteria. The OMVs of Red Complex bacteria play a role in the onset and development of oral pathological conditions such as gingivitis and periodontitis. Additionally, a substantial body of evidence supports the notion that these OMVs may exert influence on systemic pathologies, including atherosclerosis, alzheimer's, rheumatoid arthritis, and diabetes mellitus. This review will discuss the formation and composition of Red Complex bacterial OMVs, their impacts on the oral environment, the immune response, and their correlations with various systemic diseases. The suggested treatment approach by probiotics and bioactives focuses on the genetic elements that induce the production of OMVs by the Red Complex bacteria, offering a potent means to hinder the advancement of diseases propagated through these OMVs.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1607931"},"PeriodicalIF":3.1,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of primary and secondary stability of a one-piece compressive conometric implant system in the posterior upper and lower jaws.","authors":"Thabat R Al-Hity, Bilal El-Dhuwaib, Abdulsalam R Al-Zahawi, Sarhang Sarwat Gul","doi":"10.3389/froh.2025.1625593","DOIUrl":"10.3389/froh.2025.1625593","url":null,"abstract":"<p><strong>Background: </strong>Implant stability plays a key role in establishing implant osseointegration and is a crucial factor in determining the appropriate timing for functional loading with a fixed prosthesis. This study aims to investigate the primary and secondary stability of a one-piece compressive conometric implant system in the posterior upper and lower jaws.</p><p><strong>Materials and methods: </strong>A total of 46 compressive one-piece dental implants (DIs) from ROOTT Trade Company were placed in the upper and lower jaws. Ready-made conometric TEC (titanium) with a prosthesis was fixed to the abutment. Implant stability was measured using an implant stability tester (AnyCheck device; NeoBiotech, Republic of Korea) by resonance frequency analysis (RFA) at facial, oral, mesial, distal, and occlusal surfaces. These measures were collected at baseline immediately after implant insertion, after 3 months, and at 6 months. The Kruskal-Wallis test was used to compare between the time points.</p><p><strong>Results: </strong>In total, 14 patients (8 men, 6 women; mean age 61.08 years; age range 35-79 years) were included. The median baseline RFA values show statistically significant differences between maxillary [55, interquartile range (IQR): 51-61] and mandibular (64, IQR: 60-67) as well as between men (59, IQR: 53-64) and women (67, IQR: 64-69). The occlusal surface shows the highest RFA compared to other surfaces. DI stability significantly increases in the maxilla and men after 6 months compared to the baseline (<i>p</i> = 0.0006 and 0.0001, respectively).</p><p><strong>Conclusions: </strong>This study suggests that the one-piece compressive conometric implant system demonstrates reliable primary and secondary stability in the posterior upper and lower jaws, with a notable improvement after 6 months.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1625593"},"PeriodicalIF":3.1,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, regional, and national burden of periodontal diseases from 1990 to 2021 and predictions to 2040: an analysis of the global burden of disease study 2021.","authors":"Meiling Hu, Ruibin Zhang, Ren Wang, Yan Wang, Jincai Guo","doi":"10.3389/froh.2025.1627746","DOIUrl":"10.3389/froh.2025.1627746","url":null,"abstract":"<p><strong>Background: </strong>Periodontal diseases are one of the most prevalent oral diseases globally, with increasing incidence rates in recent years. This study aims to analyze the global burden and epidemiological trends of periodontal diseases from 1990 to 2021, and to forecast trends through 2040.</p><p><strong>Methods: </strong>Data on incidence, prevalence, and disability-adjusted life-years (DALYs) of periodontal diseases were extracted from the Global Burden of Disease study 2021. The analysis evaluated the global, regional, and national burden of periodontal diseases, conducted a decomposition analysis based on population growth, aging, and epidemiological changes, and examined the association between the sociodemographic index (SDI) and disease burden, and projected trends through 2040.</p><p><strong>Results: </strong>In 2021, global estimates indicated 89,613,534 (95% uncertainty interval (UI): 79,069,091-101,005,642) incident cases, 1,066,953,744 (95% UI: 896,546,186-1,234,839,287) prevalent cases, and 6,903,284 (95% UI: 2,772,284-14,106,182) DALYs due to periodontal diseases. South Asia demonstrated the highest number and age-standardized rates (ASR) of incidence, prevalence, and DALYs. Between 1990 and 2021, the ASR of prevalence and DALYs increased slightly, while the ASR of incidence remained stable worldwide. Population growth and aging were the primary contributors to changes in disease burden. A significant negative correlation was observed between the SDI and the periodontal diseases burden. Projections from 2022 to 2040 indicate annual increases in both the number and ASR of incidence, prevalence, and DALYs for periodontal diseases.</p><p><strong>Conclusions: </strong>Periodontal diseases remain a substantial global health challenge, characterized by rising incidence, prevalence, and DALYs. These findings underscore the urgent need to implement effective prevention strategies and integrate oral health services into primary care, particularly in regions with low to middle SDI, to reduce the escalating burden.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1627746"},"PeriodicalIF":3.1,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12332980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-eruptive intracoronal resorption in a 10-year-old girl: a review and case report.","authors":"Laresh Naresh Mistry, Shreyas Neelkanthan, Anusree Basu","doi":"10.3389/froh.2025.1624190","DOIUrl":"10.3389/froh.2025.1624190","url":null,"abstract":"<p><p>Pre-Eruptive Intracoronal Resorption (PEIR) is a pathological condition characterized by the resorption of dental tissues within the crown of an unerupted tooth. It is typically asymptomatic and is most often identified incidentally during radiographic examinations. The exact etiology of PEIR remains unclear, although various theories have been proposed, including developmental disturbances, trauma, and genetic factors. This article aims to provide a comprehensive review of PEIR, following the Case Report (CARE) checklist, to enhance understanding and awareness of this dental anomaly.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1624190"},"PeriodicalIF":3.1,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144801321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}