Frontiers in oral health最新文献

{"title":"Evolutionary conformation model of salivary gland lithiasis.","authors":"Álvaro Sánchez Barrueco, María Victoria López-Acevedo Cornejo, William Aragonés Sanzen-Baker, Sol López-Andrés, Gonzalo Díaz Tapia, Ignacio Alcalá Rueda, Jessica Mireya Santillán Coello, Carlos Cenjor Español, José Miguel Villacampa Aubá","doi":"10.3389/froh.2025.1610977","DOIUrl":"10.3389/froh.2025.1610977","url":null,"abstract":"<p><strong>Introduction: </strong>Salivary stones, or sialoliths, are calcified concretions forming within salivary glands and their ducts through a two-stage process: an initial formation of a central core via precipitation of inorganic material mediated by organic substances, followed by layering of additional organic and inorganic material. Substrates for sialolith formation include mucoid agglomerates, organic vesicles, foreign bodies, and bacterial biofilms. Understanding the detailed structure of sialoliths may aid in developing specific preventive or therapeutic strategies.</p><p><strong>Materials and methods: </strong>This study analyzed 137 sialoliths from 102 patients treated across three university hospitals. Stones were extracted via sialendoscopy, direct extraction, or spontaneous extrusion. Structural and compositional analyses were conducted using scanning electron microscopy (SEM-EDX) and x-ray diffraction (XRD).</p><p><strong>Results: </strong>Most sialoliths were from the submandibular gland (82%), with the remainder from the parotid gland (18%). Parotid stones predominantly exhibited irregular shapes, while submandibular stones were generally ellipsoidal. All stones demonstrated an oolitic structure characterized by a central core surrounded by concentric layers and frequently associated with bacteria. Mineral composition predominantly included octacalcium phosphate (OCP), hydroxyapatite, and whitlockite. Larger sialoliths exhibited a higher proportion of hydroxyapatite, indicating increased crystallinity compared to OCP.</p><p><strong>Discussion: </strong>Despite diverse origins and locations, sialoliths share common morphological and compositional traits. Their formation begins with heterogeneous nucleation of calcium phosphates around organic spherules, likely induced by bacterial biofilms. These initial nuclei aggregate into a central core upon which additional layers of organic and inorganic materials deposit progressively. This layering increases the size and crystallinity of the sialoliths over time. The coexistence of amorphous phases and structural heterogeneity within layers explains the variability among stones. Detailed SEM-EDX analysis supports a unified conformational model for sialoliths that integrates the interplay of organic substrates, inorganic minerals, bacterial biofilms, and temporal factors.</p><p><strong>Conclusions: </strong>Sialoliths are oolitic aggregates featuring a central core surrounded by concentric layers composed of organic and inorganic materials. Their formation process involves initial heterogeneous nucleation, bacterial influence, and progressive crystallization. This universal conformational model effectively describes sialolith formation irrespective of patient-specific or anatomical variations.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1610977"},"PeriodicalIF":3.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: The association between oral health and mental health.","authors":"Jing Kang, Huabin Luo, Jianhua Wu","doi":"10.3389/froh.2025.1610146","DOIUrl":"10.3389/froh.2025.1610146","url":null,"abstract":"","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1610146"},"PeriodicalIF":3.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the effectiveness of diode laser, fluoride varnish, and their combination in treatment of dentin hypersensitivity: a systematic review of randomized clinical trials.","authors":"Manijeh Mohammadian, Nima Jalouti, Mohsen Yazdanian, Elham Keykha, Samira Hajisadeghi","doi":"10.3389/froh.2025.1550127","DOIUrl":"10.3389/froh.2025.1550127","url":null,"abstract":"<p><strong>Background and aim: </strong>Dentin hypersensitivity (DH) has long been a challenging condition, with many treatment methods showing limited success. However, the emergence of laser therapy, particularly the significant potential of diode laser (DL) and sodium fluoride (NaF) varnish, has sparked new hope. This research is a significant step towards a more effective treatment for DH, aiming to evaluate the promising potential of DL in treating DH, both independently and in combination with fluoride varnish. By delving into this research, you are investing your time in understanding a crucial advancement in the field of dentistry.</p><p><strong>Methods: </strong>A comprehensive search was conducted across the PubMed, Scopus, and Web of Science databases, including studies published up until May 2024. Randomized clinical trials that assessed DH using a visual analog scale (VAS) score were included. Data on participant demographics, treatment types, and VAS scores were extracted by two reviewers. The risk of bias was assessed using the revised Cochrane risk-of-bias instrument for randomized trials (RoB-2).</p><p><strong>Result: </strong>Three studies met the inclusion criteria, comparing NaF varnish, DL, and their combination. Both DL and the combination of DL and NaF varnish were more effective than NaF varnish alone in reducing DH. The combined treatment showed marginally superior outcomes compared to DL alone. Significant reductions in DH were observed across all treatment groups, with the combination therapy demonstrating the most substantial and consistent improvement.</p><p><strong>Conclusion: </strong>Diode laser therapy, particularly when combined with NaF varnish, represents a promising treatment approach for DH, offering superior efficacy over NaF varnish alone. These findings suggest that combination therapy may provide longer-lasting relief, with implications for improving clinical outcomes in DH management.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1550127"},"PeriodicalIF":3.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the completeness of electronic health records in dental education: a big data study.","authors":"Tamanna Tiwari, Maxim Kondratenko, Nihmath Nasiha, Toan Ong, Sangeetha Chandrasekaran, Gary Kostbade, Zachary Giano","doi":"10.3389/froh.2025.1535164","DOIUrl":"10.3389/froh.2025.1535164","url":null,"abstract":"<p><strong>Objectives: </strong>The BigMouth Dental Data Repository is an oral health database developed from de-identified electronic health record (EHR) data from eleven dental schools within the United States. To better understand how this database can be used for further research, the repository must be analyzed for data quality, such as accuracy, consistency, and completeness. This study determined the completeness of all patient health records between 2017 and 2019, including demographic, dental, behavioral, and health history variables at the students, faculty, and resident level.</p><p><strong>Methods: </strong>This study analyzed demographic (age, gender, race/ethnicity, zip code, insurance), dental (pain ratings), behavioral (tobacco, alcohol, and drug use), and health history variables for completeness. ANOVA was conducted to detect differences in providers collecting data by year (using Tukey <i>post hoc</i> differences at <i>p</i> < .05). Effect sizes are presented by comparing students to all other provider types.</p><p><strong>Results: </strong>Overall, the data showed high completeness in demographic variables (97.6%-99.9% for age, gender, and zip code) among the total sample of 543,363 patient visits. However, lower completeness rates were found in dental and behavioral variables (ranging from 1.5% to 66.1%), suggesting potential limitations for certain research applications. The study found significant differences in the completeness of records between students, faculty, and residents. In demographic variables, students demonstrated significantly higher completeness rates than faculty across the years 2017-2019, with 79.8%, 79%, and 78.8% completeness for race/ethnicity records, respectively. Furthermore, residents and faculty exhibited significantly higher completeness rates (76.8% and 86.7%, respectively) in insurance information compared to students (56.7%). Notably, students showcased greater completeness percentages in variables related to tobacco use, alcohol use, drug use, and health history compared to both faculty and residents.</p><p><strong>Conclusion: </strong>This study underscores significant variations in the completeness of EHR data among students, faculty, and residents across different schools. Despite these variances, the overall findings suggest a robust level of completeness in the demographic and health variables within the dataset.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1535164"},"PeriodicalIF":3.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conventional scan body vs. scan bodies with auxiliary geometric devices: an <i>in vitro</i> study for edentulous full-arch implant impressions.","authors":"Francesco Gianfreda, Carlo Raffone, Mirko Martelli, Alberto Pitino, Vito Carlo Alberto Caponio, Patrizio Bollero","doi":"10.3389/froh.2025.1574149","DOIUrl":"10.3389/froh.2025.1574149","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to assess the effectiveness of an auxiliary geometric device (AGD) in enhancing the trueness of full-arch implant impressions. The primary metrics of interest were total surface deviation (TotRMS), centroid deviation (cRMS), and angular deviation. All these values are crucial for achieving a precise fit of implant-supported prostheses.</p><p><strong>Methods: </strong>A gypsum-based edentulous maxillary model with four multi-unit abutment replicas was prepared, replicating clinical scenarios. Control and experimental scan bodies were scanned using an intraoral scanner (Dexis 3800), and the resulting data were compared to a digital master model created with a structured light scanner (ATOS compact Scan 5M). The AGD was used to reduce positional errors during the scan process. Data were processed using Exocad and GOM Inspect Professional software, aligning scan body library files with mesh data using a best-fit algorithm. Angular, platform, and total deviations were calculated to assess positional trueness. A sample size of 20 scans per group was determined <i>a priori</i>, and statistical comparisons were made using Mann-Whitney <i>U</i> tests.</p><p><strong>Results: </strong>The inclusion of the AGD significantly reduced centroid root mean square (cRMS) values in all measured comparisons (<i>p</i> < 0.001), demonstrating enhanced trueness. The total body root mean square deviation <b>(</b>TotRMS) values also showed a significant reduction (<i>p</i> = 0.002). While overall angular deviation differences were not statistically significant (meanAGD = 0.38; meanNO = 0.39; where \"NO\" refers to the group without AGD), site-specific analysis revealed significant improvements at points 2.4 (<i>p</i> = 0.017) and 1.4 (<i>p</i> < 0.001). The Euclidean distance in platform deviation consistently indicated better alignment in the AGD group.</p><p><strong>Conclusion: </strong>The AGD, tested under <i>in vitro</i> conditions, significantly improved the trueness of full-arch implant impressions, particularly reducing c- and TotRMS values. These findings highlight the AGD's potential to enhance digital workflows in implant dentistry by mitigating positional discrepancies and ensuring greater trueness and precision. Future research should explore these findings in a clinical scenario.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1574149"},"PeriodicalIF":3.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of a carbonated beverage on the optical properties and microhardness of preheated bulk-fill composite resin restorations.","authors":"Nancy Soliman Farghal, Ayya Abu Shamleh, Osamah Al Hurmuzi, Okba Mahmoud","doi":"10.3389/froh.2025.1539527","DOIUrl":"10.3389/froh.2025.1539527","url":null,"abstract":"<p><strong>Introduction: </strong>Preheating the high-viscosity forms of bulk-fill resin composites is recommended to enhance their flow and adaptability. Nevertheless, the impact of preheating on their characteristics upon exposure to carbonated beverages remains unclear. This study aims to evaluate the effect of a Cola beverage on the properties of preheated and non-preheated high-viscosity bulk-fill composite resins <i>in vitro</i>.</p><p><strong>Methods: </strong>Forty disc-shaped specimens were prepared from each of BEAUTIFIL-Bulk Restorative (BB) and Filtek One Bulk-fill (FOB) composite resin, then divided into two groups (<i>n</i> = 20), either preheated to 68°C for 15 min or kept at room temperature before polymerization, then specimens were immersed in Alkozay Cola beverage for 30 days (3 periods of 15 min/day). Color stability (ΔE₀₀), surface gloss (GU) and Vickers Microhardness (VHN) were recorded before and after the Cola immersion. The data was analyzed with Two-way ANOVA, Three-way ANOVA and Tukey's HSD <i>post hoc</i> test using SPSS software at 95% significance level.</p><p><strong>Results: </strong>The color change was significantly higher in BB than FOB in all groups (<i>P</i> < 0:001), FOB had a significant reduction in color change after preheating (<i>P</i> < 0.05) while BB had no significant change (<i>P</i> > 0.05). Preheating significantly increased the gloss of BB and reduced that of FOB (<i>P</i> < 0.001), however, Cola beverage significantly reduced the gloss of all the groups (<i>P</i> < 0.001). Preheating significantly increased the microhardness of both materials (<i>P</i> < 0.001), however, Cola beverage significantly reduced the microhardness of all the groups (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Although the preheating of high-viscosity bulk-fill composites significantly improved their microhardness and improved the surface gloss of FOB, it did not protect both composites against the Cola drink attack. Preheated FOB showed improved color stability after the Cola immersion, but not to a clinically acceptable limit.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1539527"},"PeriodicalIF":3.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric and visualization analysis of temporomandibular joint osteoarthritis from 2004 to 2024.","authors":"Chi Xu, Chongqing Yu, Tao Wang, Xiang Gao","doi":"10.3389/froh.2025.1596551","DOIUrl":"10.3389/froh.2025.1596551","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular joint osteoarthritis (TMJOA) is a severe condition affecting the temporomandibular joint, impairing essential oral functions such as chewing, speaking, and swallowing. Recent studies have made significant outcomes in pathogenesis, clinical symptoms, and therapy in the field of TMJOA. However, knowledge of research trends and hotspots of TMJOA is still lacking in this field. This study conducted a bibliometric analysis of TMJOA, providing a comprehensive overview of current research hotspots and trends.</p><p><strong>Methods: </strong>A total of 584 TMJOA-related records published between 2004 and 2024 were retrieved from the Web of Science Core Collection (WoSCC) database. VOSviewer, CiteSpace, the R package \"bibliometrix\", and the Bibliometric website were used to analyze countries, institutions, journals, authors, and keywords to identify research trends in TMJOA.</p><p><strong>Results: </strong>Publications on TMJOA have shown a steady annual increase. Globally, China and the USA emerged as the leading contributors, accounting for over 60% of the publications. Sichuan University ranked first in total publications and citations, while the University of Northern Carolina led in average citations. The <i>Journal of Oral Rehabilitation</i> published the most studies, whereas the <i>Journal of Dental Research</i> had the highest impact factor (5.3) and H-index (158). Long X was the most prolific author, while Liu Y, Manfredini D, and Guarda-Narnini L were the top-cited authors with the highest H-indices. Keyword analysis revealed four primary research clusters: \"pathogenesis mechanisms\", \"clinical manifestations\", \"regeneration research\", and \"therapy research\".</p><p><strong>Conclusion: </strong>This bibliometric analysis highlights publication trends, research hotspots, citation patterns, and collaborative networks among countries, institutions, and authors in the TMJOA field. Future research is expected to focus on molecular signaling pathways and targeted therapies for TMJOA, with the ultimate goal of accelerating translational research to enhance clinical outcomes for patients.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1596551"},"PeriodicalIF":3.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of pomegranate extract on preventing dental caries: a systematic review.","authors":"Niyousha Rafeie, Yasaman Salimi, Zahra Sadat Aghamir, Amirhesam Amini, Hamed Taheri, Sarvin Sadreddini, Fatemeh Kamali, Golnesa Akbarian, Nazanin Azizi, Mobina Bagherianlemraski, Maryam Valizadeh, Farnoosh Alimohammadi, Negar Sedighnia, Mohammad Qadirifard, Mahdyieh Naziri","doi":"10.3389/froh.2025.1484364","DOIUrl":"10.3389/froh.2025.1484364","url":null,"abstract":"<p><strong>Background/purpose: </strong>The present study aimed to evaluate the effect of pomegranate extract on the prevention of dental caries compared to standard care, placebo, and no intervention.</p><p><strong>Materials and methods: </strong>A bibliographic search in four databases, including PubMed, Scopus, Google Scholar, and CENTRAL, yielded 291 studies until September 8, 2023. The search was performed among the studies written in English using the search terms \"<i>Punica granatum</i>\" AND (\"dental caries\" OR \"<i>Streptococcus mutans</i>\" OR \"tooth demineralization\") After screening the titles/abstracts and full texts of these studies, 7 articles were chosen.</p><p><strong>Results: </strong>In all 7 articles, pomegranate mouthwash was used as the intervention. In 5 studies, the control group used 0.2% chlorhexidine (CHX) mouthwash. Additionally, 4 articles reported a reduction in the mean <i>Streptococcus mutans</i> plaque count in both groups; however, better results were observed in the CHX mouthwash group. In one study, no significant difference was reported between the study and control groups. Finally, one study showed the significant superiority of a hydroalcoholic extract of pomegranate mouthwash over CHX mouthwash.</p><p><strong>Conclusion: </strong>Overall, the results suggest that pomegranate extract mouthwash is highly effective in reducing caries-causing bacteria. No side effects were reported for pomegranate use in these studies.</p><p><strong>Systematic review registration: </strong>https://osf.io/69gpc/.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1484364"},"PeriodicalIF":3.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacts of oral health on life quality metrics: correlations with job function, psychological well-being, self-perception, and dietary behavior.","authors":"Mohammad Helmi","doi":"10.3389/froh.2025.1586868","DOIUrl":"10.3389/froh.2025.1586868","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluates the impact of oral health issues on critical areas of daily functioning, including job performance, psychological well-being, self-rated oral health, and dietary habits.</p><p><strong>Methods: </strong>Utilizing NHANES data, the analysis applies Pearson correlation, multiple regression, and data visualization techniques (scatter plots, heatmaps, and box plots) to quantify associations between oral health variables, such as mouth aching (OHQ620), food avoidance (OHQ660), job difficulty due to mouth issues (OHQ640), and embarrassment (OHQ680).</p><p><strong>Results: </strong>Strong correlations were found between mouth aching and job difficulty due to mouth issues, with a Pearson correlation coefficient of 0.99, and between difficulty eating (OHQ670) and job difficulty due to mouth issues, with a coefficient of 0.98. Psychological impacts were also notable; feeling bad about one's mouth (OHQ630) had a high correlation with embarrassment (0.99), while mouth aching had a weaker association (0.88). Self-rated oral health (OHQ845) showed a negative correlation with both mouth aching (-0.83) and feeling bad about one's mouth (-0.83), indicating decreased self-assessment of oral health as symptoms increase. Multiple regression revealed that difficulty eating had a substantial positive coefficient (1.19) for food avoidance, while mouth aching had a minor negative effect (-0.13). Smoking exposure was positively associated with oral health issues, particularly with mouth aching and embarrassment.</p><p><strong>Conclusions: </strong>The findings highlight significant impacts of oral health issues on job performance, psychological well-being, and lifestyle, suggesting the need for integrated oral healthcare strategies that address both physical discomfort and emotional consequences.</p><p><strong>Practical implications: </strong>Enhanced oral health interventions focusing on symptom management and psychological support could reduce nutrition barriers, improve occupational functioning, and increase quality of life.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1586868"},"PeriodicalIF":3.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health-related quality of life in patients with periodontitis: a systematic review and meta-analysis.","authors":"Joanna Slowik, Anna Panasiuk, Marcin Kaczor, Marcin Wnuk","doi":"10.3389/froh.2025.1503829","DOIUrl":"10.3389/froh.2025.1503829","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to comprehensively evaluate the impact of periodontitis on Oral Health-Related Quality of Life (OHRQoL) using the OHIP-14 questionnaire. A quantitative meta-analysis was conducted to estimate the average effect size, taking into account the characteristics of periodontitis and the features of control groups. Additionally, associations between OHRQoL and periodontitis were explored based on participant demographics and clinical factors.</p><p><strong>Methods: </strong>We systematically searched the PubMed, Embase, and Scopus databases up to March 8, 2024. Studies included in the analysis assessed OHRQoL in patients with periodontitis (exposed group) compared to non-periodontitis individuals (non-exposed control group). A valid periodontitis diagnosis required Clinical Attachment Loss (CAL) and Pocket Probing Depth (PPD) assessments during full-mouth clinical examinations. The choice of meta-analysis model was based on an assessment of heterogeneity. The quality of the included studies was assessed using the tool developed by The National Heart, Lung, and Blood Institute (<i>N</i>HLBI).</p><p><strong>Results: </strong>Nine studies, encompassing 2,287 individuals, met the inclusion criteria. Periodontitis significantly affected the mean OHIP-14 total scores compared to controls [Weighted Mean Differences WMD random = 6.11 (95% CI: 4.23, 7.99), <i>p</i> < 0.0001], with substantial heterogeneity. Subgroup analysis did not reveal significant regional variations. Restricting the analysis to studies using the American Academy of Periodontology/European Federation of Periodontology consensus definition from 2017 yielded similar results. The negative impact of periodontitis on OHRQoL was associated with disease severity and female sex but was not influenced by the region or age of the study participants.</p><p><strong>Conclusions: </strong>Our findings confirm that periodontitis significantly impairs OHRQoL, with potential associations related to disease severity and sex. However, the limited availability of studies with matched control groups and poor data reporting quality constrains a more comprehensive assessment.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1503829"},"PeriodicalIF":3.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}