Frontiers in oral health最新文献

{"title":"Essential tremor-challenged maxillary rehabilitation using a digitally guided all-on-six implant restoration: a case report.","authors":"Shuning Zhang, Jiarui Cui, Fan He, Jiani Hu, Guangzheng Yang, Hui Huang, Jie Wang, Xinquan Jiang","doi":"10.3389/froh.2025.1663892","DOIUrl":"10.3389/froh.2025.1663892","url":null,"abstract":"<p><p>This case report describes a 73-year-old female with essential tremor who experienced significant dissatisfaction with her maxillary complete denture. Her tremor-related dexterity impairment limited her ability to manage removable prostheses, while the excessive denture volume severely disrupted speech. Moreover, her neuromuscular condition made it challenging to adapt to a new occlusal scheme. To address these issues, a digitally guided all-on-six implant-supported prosthesis was delivered under local anesthesia, preserving her pre-existing, neuromuscularly adapted occlusion with minor esthetic adjustments to the anterior teeth. At the 1-year follow-up, the patient reported high satisfaction with both esthetics and function, along with improved speech and masticatory efficiency. This report underscores the value of digital workflows in maintaining functional adaptation and providing predictable prosthodontic solutions for patients with neuromuscular impairments.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1663892"},"PeriodicalIF":3.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified maxillomandibular advancement for Eastern Asian patients with moderate or severe OSA: an anatomic and aerodynamic assessment of the upper airway.","authors":"Kan Li, Tianyu Zhao, Yukun Liu, Yang Cao, Xiang Li, Siyong Gao, Wei Sun, Tao Wang, Lingchan Zeng, Zhicai Feng, Guangsen Zheng","doi":"10.3389/froh.2025.1598511","DOIUrl":"10.3389/froh.2025.1598511","url":null,"abstract":"<p><strong>Background/purpose: </strong>Maxillomandibular advancement (MMA) is widely used for treating obstructive sleep apnea (OSA) patients. However, conventional MMA may not be suitable for Eastern Asian patients with moderate or severe OSA, as it can lead to unsatisfactory postoperative facial appearance. Hence, modified MMA was reported. Our study aims to evaluate the therapeutic effects of modified MMA on OSA and patient satisfaction with facial appearance. In addition, anatomic and aerodynamic changes in the upper airway were explored.</p><p><strong>Materials and methods: </strong>This retrospective study included 13 patients with moderate or severe OSA. Overnight polysomnography and the Epworth Sleepiness Scale (ESS) scores were recorded before operation and 6 months after operation to evaluate therapeutic outcomes. Spiral CT scans were performed for all patients to reconstruct 3D configurations of the bony structures and the upper airway. Computational fluid dynamics was performed to analyze aerodynamic characteristics. In addition, correlations between bone segment movements and improvement in airway parameters were examined.</p><p><strong>Results: </strong>Modified MMA achieved successful therapeutic and esthetic outcomes in all cases. The apnea-hypopnea index (36.05 ± 17.68 vs. 5.72 ± 4.76, <i>p</i> < 0.001) and the ESS (13.23 ± 8.9 vs. 6.23 ± 6.81 events/h, <i>p</i> < 0.05) decreased significantly, while the lowest oxygen saturation (76.54 ± 10.26% vs. 84.77 ± 6.02%, <i>p</i> < 0.05) improved greatly. Modified MMA significantly increased the total volume (6,716.55 ± 1,357.73 vs. 11,191.28 ± 2,563.79 mm³, <i>p</i> < 0.001) and the averaged cross-sectional area (117.38 ± 24.25 vs. 201.58 ± 35.76 mm², <i>p</i> < 0.001) of the upper airway. After modified MMA, the pressure drop, gas velocity, and resistance in the upper airway were all significantly decreased (<i>p</i> < 0.05). Among all the maxillary and mandible sections, the strongest correlation was observed between the advanced movement of the anterior mandible segment and anatomical characteristics of the upper airway.</p><p><strong>Conclusion: </strong>Modified MMA is an excellent therapeutic method for Eastern Asian patients with skeletal class Ⅱ dentomaxillofacial deformity suffering from moderate to severe OSA; it achieves a balance between esthetic improvement and therapeutic efficacy for OSA both anatomically and aerodynamically.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1598511"},"PeriodicalIF":3.1,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12460386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Access to oral health care and its social determinants across the lifespan in the United States.","authors":"Yau-Hua Yu","doi":"10.3389/froh.2025.1619983","DOIUrl":"10.3389/froh.2025.1619983","url":null,"abstract":"<p><strong>Background: </strong>Disparities in healthcare access, driven by socioeconomic status and social determinants of health (SDOH), contribute to poor health outcomes. While prior studies established the relationship between SDOH and care access, fewer have explored their joint relationships with social satisfaction and health challenges across the lifespan. Rather than assessing direct associations between dental care utilization and physical or mental difficulties, this study examines broader interrelationships among SDOH, access to oral health care, and self-reported health challenges.</p><p><strong>Methods: </strong>A cross-sectional study using a lifespan approach-by examining participants within discrete age groups-was conducted on 127,886 individuals aged 18 years and older who participated in the <i>All of Us</i> research program and completed the \"Basics\", \"Overall Health\" and \"Health Care Access and Utilization\" questionnaires. The distribution of participants' SDOH and self-reported health difficulties was presented and stratified by dental care utilization, income group and age across the lifespan. Multivariate logistic regression analyses were performed to assess the associations between SDOH and access to oral health care.</p><p><strong>Results: </strong>Across age groups, a consistent trend of disadvantaged social determinants associated with lacking oral health care utilization was noted. Young participants (18-35 years old) were the most likely to report not having received oral health care within the past 12 months (32.2%), worse mental health (29.6%, fair/poor), emotional problems (31.8%), and difficulties in concentrating or remembering (18%). Notably, young adults who did not visit a dentist within 12 months were also more likely to report not visiting a medical doctor (18.1%), being unable to afford copayment (69%), and more frequently using emergency or urgent care (20.2%). No insurance coverage [odds ratio (OR) = 1.67, 95% confidence interval (CI): 1.52-1.84], annual income less than $35,000 (OR = 3.79, 95% CI: 3.58-4.01), and housing instability (OR = 1.38, 95% CI: 1.32-1.44) were all significantly associated with lack of dental care.</p><p><strong>Conclusion: </strong>This study confirms that SDOH-particularly income and housing instability-significantly impact individuals' ability to afford and access healthcare services, including dental care. These disparities were most pronounced among the youngest age group. Our findings support future policy interventions aimed at integrating dental care into overall healthcare, especially during early adulthood.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1619983"},"PeriodicalIF":3.1,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12460411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision excision of mandibular anterior compound odontoma using autonomous robotic guidance: a clinical case report.","authors":"Tiankai Di, Chen Liu, Yuhan Liu, Shizhu Bai, Li-An Wu, Yujiang Chen, Yimin Zhao","doi":"10.3389/froh.2025.1661277","DOIUrl":"10.3389/froh.2025.1661277","url":null,"abstract":"<p><strong>Background: </strong>Management of compound odontomas in the pediatric anterior mandible poses significant surgical challenges due to proximity to developing tooth follicles and neurovascular structures. Conventional enucleation risks iatrogenic injury to adjacent dentoalveolar anatomy, while suboptimal bone preservation may impede permanent tooth eruption.</p><p><strong>Case description: </strong>An 8-year-old patient presented with a compound odontoma adjacent to the unerupted permanent mandibular incisor. Utilizing an autonomous robotic guidance system independently developed by our research group, we performed minimally invasive enucleation featuring: (1) virtual osteotomy pathway planning, (2) sub-millimeter precision bone removal preserving the follicular space of tooth 31, and (3) capsule dissection under optical navigation. At the 2-week follow-up, the surgical site demonstrated complete mucosal healing without neurosensory complications, and CBCT confirmed absence of residual pathology.</p><p><strong>Conclusion: </strong>Robotic-assisted enucleation enabled tissue-preserving removal of a high-risk odontoma while maintaining eruption potential. This approach represents a paradigm shift toward precision-targeted dentoalveoral surgery, particularly valuable for anatomically complex pediatric cases.</p><p><strong>Clinical trial registration: </strong>identifier [ChiCTR2400092822].</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1661277"},"PeriodicalIF":3.1,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12457339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on the prevention of tooth demineralization and the effects and mechanisms of different mineralization solutions on the metabolism of <i>Streptococcus mutans</i>.","authors":"Renze Shen, Yongmei Tan, Jinchuan Zheng, Gang Xu, Mingli Lin, Zhanchao Ye, Lingna Han","doi":"10.3389/froh.2025.1647945","DOIUrl":"10.3389/froh.2025.1647945","url":null,"abstract":"<p><strong>Objective: </strong>To compare the preventive effects of various mineralization solutions on tooth demineralization and their influence on the metabolism of <i>Streptococcus mutans (S. mutans)</i>.</p><p><strong>Methods: </strong>Pure water, Ca/P mineralization solution, Ca/P mineralization solution with fluoride, Ca/P mineralization solution with zinc, Ca/P mineralization solution with magnesium, and Ca/P mineralization solution with strontium (Sr) were prepared. Tooth fragments were immersed in these solutions at 37°C for 24 h. Surface morphology was examined by scanning electron microscopy (SEM). The relative proportions of surface elements were analyzed, and new substances formed on the tooth surface were identified. Acid-etching was performed to evaluate changes in anti-demineralization ability and wear resistance. <i>S. mutans</i> was inoculated onto tooth surfaces, bacterial adhesion was observed using SEM, and water contact angles were measured. Changes in pH and metabolites of bacterial culture media were assessed. KEGG enrichment pathway analysis was conducted to explore metabolic pathways. Amino acids and organic acids in metabolites and bacterial proliferation were evaluated. RT-PCR was used to measure key glycolysis-related gene expression to verify the production of acidic metabolites.</p><p><strong>Results: </strong>New substances were observed adhering to tooth surfaces by SEM; surfaces treated with zinc and Sr solutions were the roughest. Elemental proportion analysis indicated zinc had the highest adhesion potential, while Sr had the lowest. Newly formed substances included fluorapatite, magnesium hydroxide, and phosphate complexes. All experimental groups demonstrated improved acid resistance and good wear resistance. Sr treatment rendered tooth surfaces more hydrophilic and increased bacterial adhesion. All experimental groups inhibited acid production by <i>S. mutans</i>, particularly the fluoride group. Antibacterial tests indicated fluoride and zinc had the strongest antibacterial effects. KEGG pathway analysis suggested that the primary signaling pathways influenced by these substances were related to bacterial antibiotic formation and acid-salt metabolism. Metabolite analysis showed that experimental groups significantly inhibited the formation of acidic amino acids and organic acids, with fluoride exhibiting the most notable effect. RT-PCR results indicated experimental groups suppressed transcription of the glycolysis-related bacterial gene <i>ldh</i>, most notably fluoride. Additionally, transcription of bacterial adhesion genes decreased across experimental groups, with Sr markedly inhibiting <i>spaP</i> expression.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1647945"},"PeriodicalIF":3.1,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12454444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Advances and innovative discoveries in oral potentially malignant disorders.","authors":"Xin-Jia Cai, Saman Warnakulasuriya","doi":"10.3389/froh.2025.1688292","DOIUrl":"10.3389/froh.2025.1688292","url":null,"abstract":"","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1688292"},"PeriodicalIF":3.1,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12450894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145133047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of smokeless tobacco use and its impact on periodontal health among adults in Rajnandgaon, Chhattisgarh, India: a cross-sectional study.","authors":"Lubna Tabassum Siddiqui, Sunaina Shetty Yadadi, Anirudh B Acharya, Marwan Mansoor Mohammed, Saaid Al Shehadat, Vineet Vinay, Vijay Desai, Raghavendra M Shetty","doi":"10.3389/froh.2025.1659319","DOIUrl":"10.3389/froh.2025.1659319","url":null,"abstract":"<p><strong>Background: </strong>While the detrimental effects of smoking on periodontal health are well-established, the impact of smokeless tobacco (SLT) remains understudied, particularly in rural populations where SLT use is prevalent. The objective of the study is to (1) determine the prevalence of SLT consumption, and (2) evaluate its impact on periodontal health indicators among the adults in Rajnandgaon, Chhattisgarh, India.</p><p><strong>Methods: </strong>In this cross-sectional study, 1,404 adults from Chhattisgarh, India, were screened, of whom 806 identified as SLT users were further assessed. Demographic data, oral hygiene practices, and SLT consumption patterns were recorded via structured questionnaires. Clinical periodontal parameters, including plaque index (PI), gingival index (GI), clinical attachment loss (CAL), probing pocket depth (PPD), and gingival recession (GR), were assessed. Multivariate regression and structural equation modeling (SEM) were employed to analyze associations between SLT use and periodontal outcomes, adjusting for confounders.</p><p><strong>Results: </strong>SLT users exhibited significantly worse periodontal health than NTB users, with higher mean CAL (8.7 ± 2.18 mm vs. 3.2 ± 1.45 mm, <i>p</i> < 0.001), GR (2.99 ± 1.35 mm vs. 1.05 ± 0.82 mm, <i>p</i> < 0.001), and PPD (5.72 ± 1.69 mm vs. 2.91 ± 1.12 mm, <i>p</i> < 0.001). Gutkha and Tobacco + Lime demonstrated the strongest associations with periodontal destruction (<i>β</i> = 1.82, <i>p</i> < 0.01 and <i>β</i> = 1.64, <i>p</i> < 0.01, respectively). Prolonged SLT use (>10 years), higher frequency (>5 times/day), and lower buccal placement were significant predictors of deterioration (<i>p</i> < 0.05). SEM confirmed that SLT type, duration, and poor oral hygiene synergistically exacerbated periodontal damage (CFI = 0.92, RMSEA = 0.04).</p><p><strong>Conclusion: </strong>The prevalence of smokeless tobacco consumption in Rajnandgaon, Chhattisgarh, was found to be 58.26%, with a higher proportion of users among males (60%) compared to females (40%). SLT, particularly Gutkha, is a significant risk factor for periodontal disease, with usage patterns significantly influencing disease severity. These findings underscore the urgent need for region-specific public health interventions that target smoking cessation and improved oral hygiene practices. Future longitudinal studies should investigate causal mechanisms and the efficacy of interventions.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1659319"},"PeriodicalIF":3.1,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12446264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of species composition and cultivation condition on peri-implant biofilm dysbiosis <i>in vitro</i>.","authors":"Nils Heine, Kristina Bittroff, Szymon P Szafrański, Maya Duitscher, Wiebke Behrens, Clarissa Vollmer, Carina Mikolai, Nadine Kommerein, Nicolas Debener, Katharina Frings, Alexander Heisterkamp, Thomas Scheper, Maria L Torres-Mapa, Janina Bahnemann, Meike Stiesch, Katharina Doll-Nikutta","doi":"10.3389/froh.2025.1649419","DOIUrl":"10.3389/froh.2025.1649419","url":null,"abstract":"<p><strong>Introduction: </strong>Changes in bacterial species composition within oral biofilms, known as biofilm dysbiosis, are associated with the development of severe oral diseases. To better understand this process and help establish early detection systems, models are needed which replicate oral biofilm dysbiosis <i>in vitro</i> - ideally by also mimicking natural salivary flow conditions.</p><p><strong>Methods: </strong>For this purpose, the present study cultivated two different combinations of oral commensal and pathogenic strains - <i>Streptococcus oralis, Actinomyces naeslundii, Veillonella dispar/parvula, Fusobacterium nucleatum</i> and <i>Porphyromonas gingivalis</i> - comparatively within an established flow chamber model on the implant material titanium, and statically in 6-well plates for 21 days. Biofilm morphology, species distribution, and bacterial metabolism were analyzed by fluorescence microscopy, molecular biological methods, and metabolic interaction prediction.</p><p><strong>Results: </strong>Biofilm growth and composition were strongly influenced by bacterial species selection, and to a more minor extent, by cultivation conditions. Within the model containing <i>V. dispar</i> and a laboratory <i>P. gingivalis</i> strain, a diversification of commensal species was observed over time along with a significantly reduced pH-value. In contrast, the model containing <i>V. parvula</i> and the clinical isolate <i>P. gingivalis</i> W83, a dysbiotic shift with increased pathogen levels, pH-value, and virulence factors was achieved.</p><p><strong>Conclusion: </strong>Within the present study, different <i>in vitro</i> oral multispecies biofilm models were successfully developed. Depending on bacterial species selection, these models were able to depict the infection-associated dysbiotic shift in species composition under flow conditions solely by intrinsic interactions and without the use of external stimuli.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1649419"},"PeriodicalIF":3.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12443849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Xerostomia from age 50 to 90 years: prediction and prevalence in cross-sectional and longitudinal studies.","authors":"Ann-Katrin Johansson, Ridwaan Omar, Josefin Sannevik, Berit Mastrovito, Caroline Blomma, Anders Johansson","doi":"10.3389/froh.2025.1648038","DOIUrl":"10.3389/froh.2025.1648038","url":null,"abstract":"<p><strong>Objectives: </strong>To describe longitudinal changes and risk factors for xerostomia in two ageing samples from age 50 to 80 and from 75 to 90.</p><p><strong>Material and methods: </strong>In 1992 and 2007, postal questionnaires were sent to the total population of 50-year-olds (born 1942, 8,888 individuals) and 75-year-olds (born 1932, 5,195 individuals), respectively. The study was repeated every 5th year up to 2022. The questions encompassed self-reports on sociodemographic domains, and perceived general and oral health. Two questions on xerostomia were included: (i) \"Does your mouth feel dry during the day\" and (ii) \"Does your mouth feel dry at night\". The cross-sectional participation rate during the examination years ranged from 74.9% to 54.6% and was 39% in the longitudinal samples.</p><p><strong>Results: </strong>In the cross-sectional samples the response \"yes, often\" daytime xerostomia increased from a few percent at age 50 to 9.4% at age 80 and from 8.5% at age 75 to about 15% at age 90. The corresponding figures for reported \"yes, often\" nighttime xerostomia was from about 5% to 21% from age 50-to-80 and 19% to just above 24% from age 75-to-90. Figures for the longitudinal samples were similar for both conditions and cohorts. Women reported significantly higher prevalences of xerostomia than men at most of the examination points (<i>p</i> < 0.02 to <i>p</i> < 0.001). Nighttime xerostomia reported at baseline at ages 50 and 75 was the most common predictive significant risk factor for having \"yes, often\" both daytime and nighttime xerostomia at the end point of the study, viz. at ages 80 and 90 (OR 2.5-5.1, <i>p</i> = 0.006 to <0.001).</p><p><strong>Conclusions: </strong>\"Often\" xerostomia reported at baseline 30 and 15 year earlier was a common predictor for having xerostomia at ages 80 and 90 in addition to impaired general health, prescribed medication and doctor visits. Clinicians should be aware of the precipitating risk factors for xerostomia that may prevail earlier in life and therefore implement preventive strategies at an early stage.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1648038"},"PeriodicalIF":3.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12443795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of severity of bronchial asthma on oral health in children.","authors":"Murad Alrashdi, Abdullah Alyahya","doi":"10.3389/froh.2025.1594568","DOIUrl":"10.3389/froh.2025.1594568","url":null,"abstract":"<p><strong>Background: </strong>The relationship between asthma and oral health has garnered increasing attention due to overlapping risk factors, such as altered immune responses and behavioral changes.</p><p><strong>Objective: </strong>To assess and compare the oral health status of children with bronchial asthma to their healthy siblings and unrelated healthy controls in the Qassim region, KSA.</p><p><strong>Materials and methods: </strong>180 participants were included in the present study and were divided into 3 groups as follows: Group A: 60 children with confirmed diagnosis of long-standing bronchial asthma, group B: 60 healthy subjects who served as a negative control group, group C: 60 healthy siblings of asthmatic children served as a Sibling control group (participants had the same dietary patterns and socioeconomic standards as participants of group A). Dental caries were assessed using the Decayed, Missing, and Filled Teeth (dmft/DMFT) index, which is a standardized and widely used measure of Decayed, Missing, and Filled Teeth in dental epidemiology. Gingival health was evaluated via the Gingival Index (GI).</p><p><strong>Results: </strong><i>Post hoc</i> analysis was applied to evaluate the differences between the 3 studied groups regarding DMF score and gingival index and all these differences were found to be highly significant. Patients with bronchial asthma (Group A) were further subdivided into 3 subgroups according to severity of asthma (25 patients had mild asthma, 23 patients had moderate asthma, and 12 patients had severe asthma) based on GINA guidelines. Strikingly, all the differences between these 3 subgroups regarding demographic data, DMF score and gingival index were all insignificant. Further evaluation of each subgroup was done by applying <i>post hoc</i> analysis and each of the 3 subgroups was found to be significantly different than the positive and negative control groups regarding DMF score and gingival index.</p><p><strong>Conclusion: </strong>Bronchial asthma has direct and indirect effect (related to drug therapy) on oral health. Dealing with some modifiable cofactors could be helpful in improving oral health in children with asthma.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1594568"},"PeriodicalIF":3.1,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}