发布求助
文献互助 智能选刊 最新文献

Bulletin of Experimental Biology and Medicine最新文献

筛选
英文 中文
Inhibition of Src Attenuates Stemness and Reverses Cisplatin Resistance of Non-Small-Cell Lung Cancer Cells. 抑制Src可降低非小细胞肺癌细胞的干性并逆转顺铂耐药性。
IF 0.9 4区 医学
Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-29 DOI: 10.1007/s10517-025-06356-4
A Li, R Wang
{"title":"Inhibition of Src Attenuates Stemness and Reverses Cisplatin Resistance of Non-Small-Cell Lung Cancer Cells.","authors":"A Li, R Wang","doi":"10.1007/s10517-025-06356-4","DOIUrl":"10.1007/s10517-025-06356-4","url":null,"abstract":"<p><p>The first-line chemical drug cisplatin used to treat the non-small cell lung cancer (NSCLC) often becomes ineffective due to acquired drug resistance of cancer cells. This effect and related cancer progression are related to the presence of cancer stem cells in the tumor. Tyrosine kinase Src is responsible for the appearance and development of cancer stem cells. Here, we examined the effects of Src on the oncogenic properties of cisplatin-resistant NSCLC cell lines (H358R and A549R) and the effect of inhibition of this tyrosine kinase on the sensitivity of cancer cells to cisplatin by Western blotting and immunofluorescence staining as well as migration, invasion, sphere colony, and clone formation assays. In H358R and A549R cells, the levels of phosphorylated kinase Src (pSrc) and stemness marker CD133 were elevated in comparison with the parental ones. The cisplatin-resistant cells demonstrated increased self-renewal ability and formed significantly bigger tumor spheres than their parental cells. Inhibition of Src with its inhibitor CGP77675 attenuated stemness of H358R and A549R cells; moreover, it enhanced the inhibitory effects of cisplatin on cell proliferation, migration, and invasion. The data indicated that Src-induced stemness plays an important role in developed resistance of NSCLC cells to cisplatin. Inhibition of Src attenuated stemness and acquired resistance to cisplatin, which can be beneficial for treating the cisplatin-resistant NSCLC.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"460-466"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transtraumatic Epidural Electrostimulation Promotes the Preservation of the Spinal Cord and Skeletal Muscles in Pigs. 经创伤硬膜外电刺激促进猪脊髓和骨骼肌的保存。
IF 0.9 4区 医学
Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-29 DOI: 10.1007/s10517-025-06364-4
R V Shevchenko, R R Garifulin, V V Valiullin, F O Fadeev, A A Izmailov, A M Agaev, R R Islamov
{"title":"Transtraumatic Epidural Electrostimulation Promotes the Preservation of the Spinal Cord and Skeletal Muscles in Pigs.","authors":"R V Shevchenko, R R Garifulin, V V Valiullin, F O Fadeev, A A Izmailov, A M Agaev, R R Islamov","doi":"10.1007/s10517-025-06364-4","DOIUrl":"10.1007/s10517-025-06364-4","url":null,"abstract":"<p><p>Morphological confirmation of the recovery of the spinal cord (SC) and the skeletal muscle (m. soleus) in both hind limbs was achieved in pigs with contusion injury in the lower thoracic region (Th8-Th9), following transtraumatic epidural electrical stimulation (TEES). Sixty days after the neurotrauma model, the anterior and posterior horns of the rostral and caudal spinal cord segments were examined using histological and immunofluorescent techniques relative to the injury epicenter. In animals with a 6-week TEES regimen at the Th5 and L2 levels, a larger area of intact gray matter, a smaller number of caspase-3<sup>+</sup> cells undergoing apoptosis, decreased expression of the heat shock protein 27 (HSP27), inhibition of astrogliosis development, and an increase in the number of oligodendroglial cells were observed. This agrees with data on the suppression of m. soleus atrophy and the maintenance of its original phenotype. The information we previously received about the functional recovery of the spinal cord and the results of this study allow us to make conclusion about the morphofunctional post-traumatic recovery of the spinal cord under TEES conditions.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"503-506"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Co-Cultivation with Mesenchymal Stem Cells Does Not Affect the Efficiency of DNA Double-Strand Break Repair in Irradiated Human Non-Small Cell Lung Cancer Cells. 与间充质干细胞共培养不影响辐照人非小细胞肺癌细胞DNA双链断裂修复效率。
IF 0.9 4区 医学
Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-28 DOI: 10.1007/s10517-025-06358-2
D V Molodtsova, A N Osipov
{"title":"Co-Cultivation with Mesenchymal Stem Cells Does Not Affect the Efficiency of DNA Double-Strand Break Repair in Irradiated Human Non-Small Cell Lung Cancer Cells.","authors":"D V Molodtsova, A N Osipov","doi":"10.1007/s10517-025-06358-2","DOIUrl":"10.1007/s10517-025-06358-2","url":null,"abstract":"<p><p>The effect of the microenvironment on the efficiency of anti-cancer therapy is one of the most discussed topics in modern oncology. In this study, we evaluated the effect of co-cultivation with human mesenchymal stem cells (MSCs) on the efficiency of DNA double-strand break (DSB) repair in human non-small cell lung cancer (NSCLC) A549 cell line exposed to X-ray radiation. In addition, the effect of co-cultivation of MSCs and A549 cells on the proliferative activity of non-irradiated NSCLC was also studied. To assess the efficiency of DNA DSB repair, we analyzed the quantitative yield of residual foci of DSB marker proteins (γH2AX and 53BP1) 24 h after irradiation with doses of 2, 4, and 6 Gy. The results showed that co-cultivation with MSCs did not affect the efficiency of DNA DSB repair induced by X-rays, as well as the proliferative activity of NSCLC cells.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"473-477"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphological Characteristics of the Liver and Immunohistochemical Analysis of HSP70 Expression in Hepatocytes under the Impact of Doxorubicin and Rosuvastatin. 多柔比星和瑞舒伐他汀作用下肝脏的形态学特征及肝细胞中 HSP70 表达的免疫组化分析
IF 0.9 4区 医学
Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-28 DOI: 10.1007/s10517-025-06365-3
E L Lushnikova, E V Koldysheva, V I Kapustina, M G Klinnikova
{"title":"Morphological Characteristics of the Liver and Immunohistochemical Analysis of HSP70 Expression in Hepatocytes under the Impact of Doxorubicin and Rosuvastatin.","authors":"E L Lushnikova, E V Koldysheva, V I Kapustina, M G Klinnikova","doi":"10.1007/s10517-025-06365-3","DOIUrl":"10.1007/s10517-025-06365-3","url":null,"abstract":"<p><p>A morphological and immunohistochemical analyses of the liver of male WAG rats (n=47) were performed after isolated and combined administration of doxorubicin and rosuvastatin. Doxorubicin (7 mg/kg) was administered intraperitoneally once, while rosuvastatin (10 mg/kg) was given intragastrically daily; the animals were euthanized after 4, 14, and 21 days of experiment. The main morphological changes observed in the liver after both isolated doxorubicin administration and in combination with rosuvastatin included dystrophic and necrobiotic changes in hepatocytes, uneven congestion with the formation of thrombotic masses in the portal vein system, and pronounced perivenous edema. Isolated administration of rosuvastatin led to severe dystrophic changes in hepatocytes and fewer circulatory disturbances in the form of vascular congestion. Immunohistochemical analysis revealed nuclear, cytoplasmic, and mixed (nuclear-cytoplasmic) localization of HSP70 in hepatocytes in all experimental groups. In the liver of control rats, mixed localization of HSP70 significantly prevailed (>62% of hepatocytes; p<0.001); only nuclear localization was found in 9% of cells. When doxorubicin and rosuvastatin were administered alone or in a combination, significant translocation of HSP70 from the cytoplasm to the nucleus occurred (the index of hepatocytes with HSP70 localization in the nuclei increase by 3-4.5 times), which may reflect the cytotoxic nature of these drugs and the activation of cytoprotective mechanisms.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"507-513"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin Autofluorescence in Children with Type 1 Diabetes Mellitus, Correlation with Age, Sex, Duration, and Presence of Microvascular Complications. 1型糖尿病儿童皮肤自身荧光与年龄、性别、病程和微血管并发症的相关性
IF 0.9 4区 医学
Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-26 DOI: 10.1007/s10517-025-06360-8
M V Proskurina, T E Taranushenko, V V Salmin, N G Kiseleva
{"title":"Skin Autofluorescence in Children with Type 1 Diabetes Mellitus, Correlation with Age, Sex, Duration, and Presence of Microvascular Complications.","authors":"M V Proskurina, T E Taranushenko, V V Salmin, N G Kiseleva","doi":"10.1007/s10517-025-06360-8","DOIUrl":"10.1007/s10517-025-06360-8","url":null,"abstract":"<p><p>The UV spectra of induced autofluorescence in the skin of children and adolescents with type 1 diabetes mellitus were studied and its relationships with sex, age, duration of diabetes, and chronic complications of the disease were evaluated. The data were presented as a 2D array, the fluorescence spectra were normalized, smoothed by the moving average method with a window of 10 nm, and renormalized taking into account the coefficients found. Significant differences in skin fluorescence spectra were found in children of different ages, with increasing the disease duration and depending on the sex of the patients. When developing non-invasive methods of monitoring the state of carbohydrate metabolism, it is necessary to take into account sex and age, disease duration, and the presence of complications of type 1 diabetes mellitus.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"482-485"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Nitric Oxide and Endothelial Hyperpolarization in Relaxation of Mesenteric Arteries of Rats with Metabolic Syndrome. 一氧化氮和内皮超极化在代谢综合征大鼠肠系膜动脉松弛中的作用
IF 0.9 4区 医学
Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-26 DOI: 10.1007/s10517-025-06345-7
G I Lobov, I A Tsareva
{"title":"The Role of Nitric Oxide and Endothelial Hyperpolarization in Relaxation of Mesenteric Arteries of Rats with Metabolic Syndrome.","authors":"G I Lobov, I A Tsareva","doi":"10.1007/s10517-025-06345-7","DOIUrl":"10.1007/s10517-025-06345-7","url":null,"abstract":"<p><p>Changes in the relative contribution of endothelium-produced vasodilators to the modulation of mesenteric artery reactivity were studied in Wistar rats treated with 20% fructose for 16 and 32 weeks. Rats that consumed fructose developed symptoms of metabolic syndrome. Acetylcholine-induced relaxation of phenylephrine-precontracted mesenteric arteries was reduced in rats with metabolic syndrome. The NO-mediated component of acetylcholine-induced relaxation was reduced in these rats. At the same time, arterial relaxation mediated by endothelium-dependent hyperpolarization was increased. Endothelium-independent relaxation of mesenteric arteries to sodium nitroprusside in rats with metabolic syndrome was the same as in the arteries of control rats. These results suggest that the increased contraction of mesenteric arteries caused by phenylephrine in rats with metabolic syndrome is due to decreased NO production by the endothelium. Endothelium-dependent hyperpolarization appears to partially compensates for this dysfunction.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"404-409"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression of the Extracellular Domain of the Thyrotropin Receptor Based on mRNA Isolated from Thyroid Tissue and Whole Blood of Patients with Toxic Diffuse Goiter (Graves' Disease). 基于中毒性弥漫性甲状腺肿（Graves病）患者甲状腺组织和全血mRNA的促甲状腺素受体胞外结构域的表达
IF 0.9 4区 医学
Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-28 DOI: 10.1007/s10517-025-06351-9
A V Zubkov, L G Butova, N S Kuzmina, I V Zubkova, V V Fadeev, O A Svitich
{"title":"Expression of the Extracellular Domain of the Thyrotropin Receptor Based on mRNA Isolated from Thyroid Tissue and Whole Blood of Patients with Toxic Diffuse Goiter (Graves' Disease).","authors":"A V Zubkov, L G Butova, N S Kuzmina, I V Zubkova, V V Fadeev, O A Svitich","doi":"10.1007/s10517-025-06351-9","DOIUrl":"10.1007/s10517-025-06351-9","url":null,"abstract":"<p><p>Fragments of the thyrotropin receptor gene (TSHR) encoding 432- and 389-bp regions of the extracellular domain corresponding to the autoantibody binding sites in autoimmune diseases of the thyroid gland (Graves' disease and Hashimoto's thyroiditis, respectively) were cloned based on mRNA isolated not only from the thyroid tissue, but also from the whole blood of patients with toxic diffuse goiter (Graves' disease). In a group of 18 patients, the 432-bp fragment was detected in 6 patients and the 389-bp fragment was detected in 3 patients. In one patient, both fragments were isolated from the blood. The results indicate that TSHR is expressed in the blood in 30% of patients with Graves' disease.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"431-436"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genoprotective Properties of para-Tyrosol against Doxorubicin-Induced DNA Damage in Sperm and Testicular Tissue Cells of Rats. 对酪醇对阿霉素诱导的大鼠精子和睾丸组织细胞DNA损伤的基因保护作用。
IF 0.9 4区 医学
Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-28 DOI: 10.1007/s10517-025-06374-2
T G Borovskaya, A V Vychuzhanina, Yu A Schemerova, L A Stremlina, V E Goldberg, A M Dygai, V V Zhdanov
{"title":"Genoprotective Properties of para-Tyrosol against Doxorubicin-Induced DNA Damage in Sperm and Testicular Tissue Cells of Rats.","authors":"T G Borovskaya, A V Vychuzhanina, Yu A Schemerova, L A Stremlina, V E Goldberg, A M Dygai, V V Zhdanov","doi":"10.1007/s10517-025-06374-2","DOIUrl":"10.1007/s10517-025-06374-2","url":null,"abstract":"<p><p>The effect of para-tyrosol (PT), a hydroxyalkylphenol exhibiting antioxidant properties, on the level of DNA damage in testicular tissue cells and sperm of rats treated with doxorubicin was studied using the DNA comet assay. N-acetylcysteine (NAC) was used as a reference drug. It was found that both drugs reduced the number of DNA breaks in rat testicular tissue cells (by 46-48%). The antigenotoxic effect, judging by %DNA in tail, in relation to spermatozoa was detected only in PT. The number of DNA damage in male germ cells after treatment with PT was reduced by 52% from the control (administration of doxorubicin alone). The results suggest that it is advisable to use PT in order to reduce the genotoxicity of doxorubicin, in the therapy of Hodgkin lymphoma (HL) in treatment regimens containing this anthracycline antibiotic.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"567-570"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of the Breast Tumor Stromal Fibroblasts on Immunological Processes In Vitro. 乳腺肿瘤间质成纤维细胞对体外免疫过程的影响。
IF 0.9 4区 医学
Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-29 DOI: 10.1007/s10517-025-06372-4
R Yu Saryglar, A Yu Lupatov, I V Vakhrushev, S Sh Karshieva, O A Bystrykh, A V Kuprin, K N Yarygin
{"title":"Influence of the Breast Tumor Stromal Fibroblasts on Immunological Processes In Vitro.","authors":"R Yu Saryglar, A Yu Lupatov, I V Vakhrushev, S Sh Karshieva, O A Bystrykh, A V Kuprin, K N Yarygin","doi":"10.1007/s10517-025-06372-4","DOIUrl":"10.1007/s10517-025-06372-4","url":null,"abstract":"<p><p>The effects of stromal cell cultures isolated from breast cancer tissue on the differentiation and maturation of dendritic cells and proliferation of lymphocytes were studied in vitro. The derived cultures had the fibroblast-like morphology and carried mesenchymal markers CD73 and CD90 in the absence of epithelial (CD326, CD24) and macrophage (CD68) markers. The cells also expressed CD44, CD10, and CD29 and had low levels of HLA-ABC expression. Intracellular expression of fibroblast activation protein (FAP), tenascin C, and α-SMA indicated their activated state and stromal origin. Analysis of the functional properties of the cells revealed their ability to suppress differentiation of dendritic cells from monocytes, as well as the proliferation of T lymphocytes. However, they had no significant effect on DC maturation. The results demonstrate that fibroblasts in the tumor stroma of breast cancer may have a suppressive effect on important mechanisms of the adaptive immunity and can be involved in the process of tumor escape from the immunological control.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"552-559"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Possibilities of Restoring Impaired Cognitive Functions Using Non-Invasive Activation of Neuroplasticity Mechanisms. 利用非侵入性激活神经可塑性机制恢复受损认知功能的可能性
IF 0.9 4区 医学
Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-26 DOI: 10.1007/s10517-025-06344-8
A I Fedotchev
{"title":"Possibilities of Restoring Impaired Cognitive Functions Using Non-Invasive Activation of Neuroplasticity Mechanisms.","authors":"A I Fedotchev","doi":"10.1007/s10517-025-06344-8","DOIUrl":"10.1007/s10517-025-06344-8","url":null,"abstract":"<p><p>Negative consequences of various cognitive impairments accompanying many CNS diseases require reliable means for restoring impaired cognitive functions. A promising approach successfully used for this purpose and actively developing line of research is non-invasive brain stimulation that involves neuroplasticity mechanisms in the treatment process. The purpose of this work was to analyze publications of the last 5 years and consider the effects of the used non-invasive stimulation depending on the conditions and parameters of their organization. Examples of successful use of non-invasive brain stimulation with and without feedback from the patient's own bioelectric characteristics, as well as with the use of preliminary activation of neuroplasticity processes using priming were analyzed. The results of the author's own research are presented, demonstrating the possibilities of restoring impaired cognitive functions using EEG-guided light and music stimulation.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"399-403"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信