Local Hemostatic and Wound-Healing Agent in a Liquid Dosage Form.

IF 0.6 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Bulletin of Experimental Biology and Medicine Pub Date : 2025-05-01 Epub Date: 2025-07-18 DOI:10.1007/s10517-025-06428-5

T G Khonina, S G Alekseenko, M N Dobrinskaya, N V Izmozherova, L P Larionov, D S Tishin, E V Shadrina, V M Frolova, A V Zamyatin, O N Chupakhin

引用次数: 0

Abstract

We propose a composition of a local hemostatic and wound-healing agent in a liquid dosage form, a water-glycerol colloidal suspension containing active substances (silicon and iron glycerolates and chitosan) and an auxiliary substance polyvinylpyrrolidone. The agent is nontoxic and exhibits high hemostatic activity (that was practically the same at different contents of iron (III) monoglycerolate (0.40 and 0.80 wt%)) and pronounced wound-healing properties.

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局部止血和伤口愈合液体剂型。

我们提出了一种局部止血和伤口愈合剂的液体剂型组合物，一种含有活性物质（硅、铁甘油酸酯和壳聚糖）的水-甘油胶体悬浮液和一种辅助物质聚乙烯吡罗烷酮。该制剂无毒，具有高止血活性（在不同含量的单甘油三酯铁（III）（0.40 wt%和0.80 wt%）下几乎相同）和明显的伤口愈合性能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bulletin of Experimental Biology and Medicine 医学-医学：研究与实验

CiteScore

1.50

自引率

14.30%

发文量

265

审稿时长

2 months

期刊介绍： Bulletin of Experimental Biology and Medicine presents original peer reviewed research papers and brief reports on priority new research results in physiology, biochemistry, biophysics, pharmacology, immunology, microbiology, genetics, oncology, etc. Novel trends in science are covered in new sections of the journal - Biogerontology and Human Ecology - that first appeared in 2005. World scientific interest in stem cells prompted inclusion into Bulletin of Experimental Biology and Medicine a quarterly scientific journal Cell Technologies in Biology and Medicine (a new Russian Academy of Medical Sciences publication since 2005). It publishes only original papers from the leading research institutions on molecular biology of stem and progenitor cells, stem cell as the basis of gene therapy, molecular language of cell-to-cell communication, cytokines, chemokines, growth and other factors, pilot projects on clinical use of stem and progenitor cells. The Russian Volume Year is published in English from April.