Advances in neurology and neuroscience最新文献_第3页

Screening for Autism Spectrum Disorders in Underserved Populations: Global Versus Specific Surveillance Instruments 在服务不足人群中筛查自闭症谱系障碍:全球与特定监测工具

Advances in neurology and neuroscience Pub Date : 2022-09-27 DOI: 10.33140/an.05.03.06

{"title":"Screening for Autism Spectrum Disorders in Underserved Populations: Global Versus Specific Surveillance Instruments","authors":"","doi":"10.33140/an.05.03.06","DOIUrl":"https://doi.org/10.33140/an.05.03.06","url":null,"abstract":"Objective: The identification of developmental delays during well-child visits is insufficient with clinical judgment alone (30-50%). Method: We analyzed the usefulness of clustering communication and social-personal areas from neurodevelopmental screening ASQ-3 and Denver II PRUNAPE questionnaires, compared with M-CHAT and ADOS as the initial screening for detection of Autism Spectrum Disorders (ASD) at well-child controls at primary-care settings in lowand middle-income countries (LMIC). Results: One hundred children at the Department of Pediatrics from 12 to 66 months (average: 35 months), were assessed by a developmental pediatrician, trained and supervised by ECHO-model. The assessment was completed with a full assessment for autism with a child neurologist, and a child-juvenile psychiatrist. Thirty-one of 100 children arrived at autism spectrum disorder diagnostic criteria. Conclusion: Failure at ASQ-3 communication plus social-personal clusters was in good agreement with M-CHAT to predict risk criteria for autism compared with a full assessment protocol. Clustering Communication and Personal-Social developmental skills from global screeners were sufficient at the pediatric visits, let differential diagnoses with global developmental delay, and communication developmental disorders. These scales covered a wide range of ages for early identification of children with an autism spectrum disorder in primary care settings within an on-site or online format","PeriodicalId":93246,"journal":{"name":"Advances in neurology and neuroscience","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44026233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Successful Intravenous Thrombolysis for A Common Carotid Artery Dissection Stroke Revealing Takayasu’s Arteritis: A Case Report from Cameroon 成功的静脉溶栓治疗颈总动脉夹层卒中，显示Takayasu动脉炎:喀麦隆1例报告

Advances in neurology and neuroscience Pub Date : 2022-08-30 DOI: 10.33140/an.05.03.05

引用次数: 0

Mathematical Modeling of Stress Using Fractal Geometry; The Power Laws and Fractal Complexity of Stress 应用分形几何对应力进行数学建模；应力的幂律与分形复杂性

Advances in neurology and neuroscience Pub Date : 2022-08-30 DOI: 10.33140/an.05.03.04

{"title":"Mathematical Modeling of Stress Using Fractal Geometry; The Power Laws and Fractal Complexity of Stress","authors":"","doi":"10.33140/an.05.03.04","DOIUrl":"https://doi.org/10.33140/an.05.03.04","url":null,"abstract":"In this study, we analyze the physiological data during real-world driving tasks to determine whether driver’s relative stress is mono-fractal or multi-fractal. We use the PhysioNet database including long term ECG recordings from 15 healthy volunteers, taken while they were driving on a prescribed route including city streets and highways in and around Boston, Massachusetts. The vibration analysis such as power spectral densities (PSD) analysis has been performed to estimate the exponent from realizations of these pro- cesses and to find out if the signal of interest exhibits a power-law PSD. Multifractal dynamics of heartbeat interval signals have been assessed by multifractal spectrum analysis to explore the possibility that ECG recordings belong to class of multi-fractal process for which a large number of scaling exponents are re- quired to characterize their scaling structures. We apply Higuchi algorithm to find the fractal complexity of each cardiac rhythm for different time intervals. According to our analysis, we investigate that driver’s ECG signals under relative stress follows fractal behavior unlike control healthy signals which are multi-fractal. Our findings provide a comprehensive framework for detect stress and differentiate people who experience stress with normal people without stress which is crucial in finding the best diagnostic and controlling strat- egy in fight against many health problems due to stress, such as high blood pressure, heart disease, obesity and diabetes. Moreover, being able to recognize stress can help us to manage it.","PeriodicalId":93246,"journal":{"name":"Advances in neurology and neuroscience","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47711882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Recent Advances in Pancreatic Encephalopathy 胰腺性脑病研究进展

Advances in neurology and neuroscience Pub Date : 2022-07-14 DOI: 10.33140/an.05.03.03

引用次数: 0

A step by step guidelines to project the COVID-19 cases using a Deep Learning Approach 使用深度学习方法预测新冠肺炎病例的分步指南

Advances in neurology and neuroscience Pub Date : 2022-07-14 DOI: 10.33140/an.05.03.02

{"title":"A step by step guidelines to project the COVID-19 cases using a Deep Learning Approach","authors":"","doi":"10.33140/an.05.03.02","DOIUrl":"https://doi.org/10.33140/an.05.03.02","url":null,"abstract":"Background: Numerous mathematical models have been developed to forecast COVID-19 cases and helped to plan effectively by strengthening public health infrastructure and services. Many researchers incorporated the long-short term memory model (LSTM) but they have not clearly explained the workflow and steps involved in this model. Moreover, being relatively new, these models are not yet popular among biomedical researchers due to a lack of expertise. This paper presents such models as a tutorial for easy understanding and appropriate use. This includes Python codes and real-time data with instructions for implementation to forecast pandemics like COVID-19. Data and Methods: Daily cases in India from 1-Dec-2021 to 10-Feb-2022 and, in the UK from 1-May-2021 to 10-Feb-2022 were used to train the models. We used Convolutional-LSTM (CNN-LSTM) model and simple LSTM models to forecast COVID-19 cases. Models were validated using data from 11 to 25-Feb-2022. Results: CNN-LSTM and simple LSTM were fitted very well with R2 0.95 and 0.97 for India. The models were validated with RMSE and it was 9972.81 and 19285.57 for CNN-LSTM and the simple LSTM model. The R2 value of CNN-LSTM and simple LSTM models for UK data were 0.77 and 0.84 respectively. RMSE was 12111.95 for CNN-LSTM and 8935.75 for simple LSTM in the validation. Conclusion: Simple LSTM works better while training whereas the performance of CNN-LSTM was found to be better in validation. Therefore, it is suggested that train various models instead of sticking to one and revise them regularly as the behavior of an epidemic generally changes over time.","PeriodicalId":93246,"journal":{"name":"Advances in neurology and neuroscience","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45339573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Presentation of Anti-Gad Associated Neurological Disorder in A Fifteen-YearOld Girl 15岁女孩罕见的抗Gad相关神经系统疾病

Advances in neurology and neuroscience Pub Date : 2022-07-14 DOI: 10.33140/an.05.03.01

引用次数: 0

Interaction Between anti-Alzheimer’s Disease Drugs and Antipsychotic Agents in the Treatment of Behavioral and Psychological Symptoms: Extrapyramidal Side Effects 抗阿尔茨海默病药物与抗精神病药物在治疗行为和心理症状中的相互作用:锥体外系副作用

Advances in neurology and neuroscience Pub Date : 2022-06-30 DOI: 10.33140/an.05.02.09

{"title":"Interaction Between anti-Alzheimer’s Disease Drugs and Antipsychotic Agents in the Treatment of Behavioral and Psychological Symptoms: Extrapyramidal Side Effects","authors":"","doi":"10.33140/an.05.02.09","DOIUrl":"https://doi.org/10.33140/an.05.02.09","url":null,"abstract":"Alzheimer’s disease (AD) is the most common dementia type, accounting on its own for almost 70% of all dementia cases. Behavioral and psychological symptoms of dementia (BPSD) afflict most patients with dementia, especially those with Alzheimer’s disease (AD). Treatment options for BPSD include pharmacological and nonpharmacological approaches. However, behavioral symptoms are not always controllable with non-pharmacological intervention, and the psychotropic class of medication more frequently prescribed for behavioral symptoms are atypical antipsychotics. Antipsychotic drugs are often used for the treatment of BPSD. They are prescribed alone or in conjunction with anti-dementia. However, antipsychotic therapy is not free from several, and often serious, adverse events. For instance, it is well known that antipsychotic drugs commonly cause serious extrapyramidal side effects (EPS). It is imperative for clinicians to understand that 5-HT1A receptors or blockade of 5-HT2, 5-HT3 and 5-HT6 receptors can alleviate EPS induction by antipsychotics agent. It is therefore important to understand that appropriate drug choice and combination strategy are important in the treatment of BPSD. I point out that antipsychotic drugs can have extrapyramidal side effects, including parkinsonian symptoms, also when used in AD, and argument drug choice and combination strategies as cholinesterase inhibitors and antipsychotic drugs. Additionally, the advantages and limitation of antipsychotic drugs have been evaluated.","PeriodicalId":93246,"journal":{"name":"Advances in neurology and neuroscience","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43695575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anaplastic Meningioma Who Grade III: Case Report and Review of Immunohistopathological Characteristics III级无定形脑膜瘤：病例报告及免疫组织病理学特征回顾

Advances in neurology and neuroscience Pub Date : 2022-06-30 DOI: 10.33140/an.05.02.07

Kai Shu, Wei Jiang, T. Lei

{"title":"Anaplastic Meningioma Who Grade III: Case Report and Review of Immunohistopathological Characteristics","authors":"Kai Shu, Wei Jiang, T. Lei","doi":"10.33140/an.05.02.07","DOIUrl":"https://doi.org/10.33140/an.05.02.07","url":null,"abstract":"Introduction: Anaplastic meningiomas constitute about 2% of all intracranial meningiomas and are known to be aggressive with a mean overall survival and mean relapse-free survival of 3.3 years and 2.7 years respectively. We treated a patient with a World Health Organization (WHO) grade III Anaplastic Meningioma, a rare histological variant of convexity meningiomas in which intraoperatively we found the tumor mass was unique of mixed characteristics particularly peritumoral subdural effusion Research Question: We show in this case report that convexity lesions presenting with subdural lesions should be highly suspected for WHO III anaplastic meningiomas backed with the immunohistopathological findings. Material and Methods: Routine computed tomography for patients with neurologic signs and symptoms which reveal a convexity peri-tumoral subdural collection should be suspected for WHO III anaplastic meningiomas. Surgery and adjuvant radiotherapy offered a good clinical outcome. Results: Postoperative the patient described a gradual improvement of the of expressive aphasia, deficits in speech, detectable personality changes or motor/sensory deficits. MRI at the three-month, six-month, one- year and two-year postoperative follow-up, revealed no evidence of residual tumor nor any observed recurrence nor recurrence of pre-operative symptoms. Discussion and Conclusion In this paper, we present the rare radiological presentation and immunohistopathological characteristics of this WHO III Grade III anaplastic meningioma. WHO III anaplastic meningiomas should be considered in the differential diagnosis of intracranial tumors which present with peritumoral subdural collection on routine contrast tomography imaging. Our findings may contribute to the literature of the histopathological nature and behavior of this tumor subtype.","PeriodicalId":93246,"journal":{"name":"Advances in neurology and neuroscience","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49270089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Total Family Risk in Vulnerable Families 弱势家庭的总家庭风险

Advances in neurology and neuroscience Pub Date : 2022-06-30 DOI: 10.33140/an.05.02.10

引用次数: 0

Effect of Simvastatin Intracerebroventricular Injection (ICV) On Memory and Anxiety in Male Rats in The Presence of Vitamin D Supplementation 补充维生素D后辛伐他汀脑室注射(ICV)对雄性大鼠记忆和焦虑的影响

Advances in neurology and neuroscience Pub Date : 2022-06-30 DOI: 10.33140/an.05.02.06

引用次数: 0