A Rare Presentation of Anti-Gad Associated Neurological Disorder in A Fifteen-YearOld Girl

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Abstract

Anti-GAD antibodies have been associated with numerous neurological conditions that have a wide variety of presentations. These conditions include limbic encephalitis, stiff person syndrome, opsoclonus-myoclonus-ataxia syndrome, cerebellar ataxia, and status epilepticus. In this paper, we aimed to present a female patient admitted with complaints of acute weakness and right peripheral facial palsy, pancytopenia, hepatosplenomegaly, and anti-glutamate decarboxylase antibody and report the diversity and clinical features of neurological diseases associated with anti-glutamate decarboxylase antibodies. Conclusion Besides the common primary syndromes, other new clinical and neurological manifestations have been associated with anti- anti-glutamate decarboxylase antibodies.
15岁女孩罕见的抗Gad相关神经系统疾病
抗GAD抗体与多种表现形式的神经系统疾病有关。这些情况包括边缘脑炎、强直综合征、视锁肌痉挛性共济失调综合征、小脑共济失调和癫痫持续状态。在本文中,我们旨在介绍一名因急性虚弱和右周围性面瘫、全血细胞减少症、肝脾肿大和抗谷氨酸脱羧酶抗体而入院的女性患者,并报告与抗谷氨酸脱羧酶抗体相关的神经系统疾病的多样性和临床特征。结论除了常见的原发性综合征外,其他新的临床和神经系统表现也与抗谷氨酸脱羧酶抗体有关。
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