Brazilian oral researchPub Date : 2025-06-02eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.058
Dandara Andrade de Santana, Yann Victor Paiva Bastos, Paulo Tambasco de Oliveira, Bruno Cunha Pires, Flávia Caló Aquino Xavier, Águida Cristina Gomes Henriques Leitão, Larissa Abbehusen Couto, André Sampaio Souza, Luciana Maria Pedreira Ramalho, Patrícia Ramos Cury, Jean Nunes Dos Santos
{"title":"Medication-related osteonecrosis of the jaws: a series of 22 cases highlighting their histopathological features.","authors":"Dandara Andrade de Santana, Yann Victor Paiva Bastos, Paulo Tambasco de Oliveira, Bruno Cunha Pires, Flávia Caló Aquino Xavier, Águida Cristina Gomes Henriques Leitão, Larissa Abbehusen Couto, André Sampaio Souza, Luciana Maria Pedreira Ramalho, Patrícia Ramos Cury, Jean Nunes Dos Santos","doi":"10.1590/1807-3107bor-2025.vol39.058","DOIUrl":"10.1590/1807-3107bor-2025.vol39.058","url":null,"abstract":"<p><p>This study aimed to assess the clinicopathological characteristics of medication-related osteonecrosis of the jaw (MRONJ), addressing histopathological features and bone structure. Twenty-two MRONJ patients were retrospectively evaluated for osteonecrosis, osteomyelitis, bacterial colonization, bone resorption, reactive bone, osteon-like structure, lamellar bone, and basophilic lines. Specific staining and fluorescence and polarized light microscopy assessments were also performed. The mandible was significantly more affected by MRONJ. There was a predominance of African-Brazilian women aged sixty and older. Osteomyelitis was present in 82% of patients. Actinomycosis was observed in 36.4% of MRONJ patients. Osteoclasts were absent in MRONJ but bone resorption was often seen. Basophilic lines were observed in more than 80% of the patients. The MRONJ patients exhibited lamellar bone with osteon-like structures. This study provided important insight into MRONJ, demonstrating a diverse histopathological spectrum and infection with Actinomyces and fungi. The condition was characterized by a necrotized lamellar bone structure and more frequently affected the mandible of older women.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e058"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-06-02eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.061
Amanda Garcia Alves Maliza, Renata Maíra de Souza Leal, Bruno Cavalini Cavenago, Murilo Priori Alcalde, Rodrigo Ricci Vivan, Marco Antônio Húngaro Duarte
{"title":"Endodontic retreatment of curved canals using Reciproc, Hyflex CM and Prodesign Duo Hybrid Systems.","authors":"Amanda Garcia Alves Maliza, Renata Maíra de Souza Leal, Bruno Cavalini Cavenago, Murilo Priori Alcalde, Rodrigo Ricci Vivan, Marco Antônio Húngaro Duarte","doi":"10.1590/1807-3107bor-2025.vol39.061","DOIUrl":"10.1590/1807-3107bor-2025.vol39.061","url":null,"abstract":"<p><p>The aim of this ex vivo study was to evaluate the efficacy of the Reciproc, Hyflex CM, and ProDesign Duo Hybrid in the retreatment of mesial root canals with Vertucci Type 4 of mandibular molars with curvatures between 10 and 20 degrees. Forty-five mesial roots of mandibular molars were prepared up to size 25.06 Nickel-Titanium (NiTi) file and filled by the single cone technique. The roots were then divided into 3 groups according to retreatment procedures: Reciproc R25 followed by R40; Hyflex 25.04 followed by 40.04; ProDesign Duo Hybrid 25.06 followed by 40.05. The canals were irrigated with 1 mL 1% sodium hypochlorite, and a final rinse was performed with 5 mL 17% EDTA for 3 minutes. Microcomputed tomography scans were performed in each step of the procedure to evaluate root canal transportation at distances of 2, 4, 6, 8 and 10 mm from the apex and volume of endodontic filling remaining at segments of 1-3, 3-5, and 5-7 mm from the apex. The filling material that was not removed during retreatment was evaluated by confocal laser scanning and the percentage after each procedure was expressed in terms of percentage of the initial root-filling material volume. The time taken to remove the material and re-instrumentation was measured in seconds with a digital chronometer. Statistical analysis was performed with t-paired, ANOVA, Kruskal-Wallis and Friedman tests (p < 0.05). In all groups, sections at 4, 6, 8, and 10 mm from the apex were transported to the danger zone, towards the furcation. However, the section at 2 mm from the apex was transported in opposite direction to the furcation, but no statistically significant differences (p > 0.05) in canal transportation and filling material removal were found between the 3 groups. Filling removal and re-instrumentation took significantly (p < 0.05) less time in the Reciproc group. None of the retreatment techniques completely removed the root fillings. The results suggest that no difference exists between the groups in apical transportation of curved canals. The Reciproc system took less time for filling removal and re-instrumentation and the combination of reciprocating and rotary files in the retreatment of curved canals was as efficient as rotary and reciprocating motion.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e061"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-05-23eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.032
Ana Luiza Peres Baldiotti, Gabrielle Amaral-Freitas, Mariane Carolina Faria Barbosa, Paula Rocha Moreira, Renata de Castro Martins, Renato Assis Machado, Ricardo Della Coletta, Michelle Nascimento Meger, Saul Martins Paiva, Rafaela Scariot, Fernanda de Morais Ferreira
{"title":"Temporomandibular joint disorders, happiness, and COMT, HTR2A and FKBP5 polymorphisms in adolescents: a cross-sectional study.","authors":"Ana Luiza Peres Baldiotti, Gabrielle Amaral-Freitas, Mariane Carolina Faria Barbosa, Paula Rocha Moreira, Renata de Castro Martins, Renato Assis Machado, Ricardo Della Coletta, Michelle Nascimento Meger, Saul Martins Paiva, Rafaela Scariot, Fernanda de Morais Ferreira","doi":"10.1590/1807-3107bor-2025.vol39.032","DOIUrl":"10.1590/1807-3107bor-2025.vol39.032","url":null,"abstract":"<p><p>Temporomandibular joint disorder (TMD) has a multifactorial etiology involving psychological and genetic aspects. This condition commonly begins in adolescence, which is a period of emotional, physical, and psychological maturation. The aim of the present study was to investigate associations between temporomandibular joint (TMJ) disorder and happiness as well as polymorphisms in the COMT, HTR2A, and FKBP5 genes in Brazilian adolescents. A cross-sectional study was conducted with 90 adolescents aged 13 to 18 years. TMD was diagnosed using the RDC/TMD. The Subjective Happiness Scale (SHS) was used to assess happiness. Saliva samples were collected for the analysis of genomic DNA and genotyping of single nucleotide polymorphisms in the COMT (rs165656, rs174675), HTR2A (rs6313, rs4941573), and FKBP5 (rs1360780, rs3800373) genes using real-time PCR (Taqman method). Bivariate, unadjusted, and adjusted binary logistic regression analyses were performed (p < 0.05). Happiness was associated with TMD in the adolescents (OR=1.37; 95%CI: 1.02-1.85; p = 0.037). The rs174675 polymorphism in the COMT gene was significantly associated with TMD (OR = 0.18; 95%CI: 0.04-0.74; p = 0.018). No associations were found between TMD and polymorphisms in HTR2A and FKBP5 genes (p > 0.05). TMD was associated with happiness, as adolescents who considered themselves less happy were more likely to have this disorder. The diagnosis of TMD was also associated with the rs174675 polymorphism in the COMT gene, as the prevalence of the disorder was higher among homozygous C Brazilian adolescents than in heterozygous CT individuals.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e032"},"PeriodicalIF":1.5,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12108116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-05-23eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.028
Débora Costa Ruiz, Rocharles Cavalcante Fontenele, Amanda Farias-Gomes, Hugo Gaêta-Araujo, Matheus Lima Oliveira, Deborah Queiroz Freitas, Francisco Haiter-Neto
{"title":"Influence of a portable X-ray device in the diagnosis of proximal caries lesions.","authors":"Débora Costa Ruiz, Rocharles Cavalcante Fontenele, Amanda Farias-Gomes, Hugo Gaêta-Araujo, Matheus Lima Oliveira, Deborah Queiroz Freitas, Francisco Haiter-Neto","doi":"10.1590/1807-3107bor-2025.vol39.028","DOIUrl":"10.1590/1807-3107bor-2025.vol39.028","url":null,"abstract":"<p><p>This study aimed to evaluate the influence of a portable X-ray device on the diagnosis of proximal caries lesions. For that, radiographs of 40 human teeth with white spots or color changes in enamel and/or dentin were acquired using the Eagle X-ray portable device (Alliage, São Paulo, Brazil) set at 2.5 mA, 60 kVp and an exposure time of 0.5 s (1.25 mAs). Then, new radiographs of the teeth were acquired using the Focus X-ray wall-mounted device (Instrumentarium, Tuusula, Finland) set at 7 mA, 70 kVp, and exposure time of 0.16 s (1.12 mAs). Five oral and maxillofacial radiologists individually assessed the radiographs. Area under the receiver operating characteristic curve (AUC), sensitivity, and specificity were calculated from the responses of the five examiners and compared between the devices tested using Student's t test. Significance level was set at 5% (α = 0.05). The weighted Kappa index evaluated the intra- and inter-examiner agreements for caries lesions diagnosis. The use of a portable X-ray device did not influence on AUC, sensitivity and specificity metrics for the diagnosis of caries lesions (p > 0.05). The intra- and inter-examiner agreements for the caries lesions diagnosis ranged from substantial to almost perfect (0.646-0.859) and moderate to substantial (0.491-0.617), respectively. The diagnostic accuracy for detecting proximal caries lesions is not impaired when using a portable X-ray device.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e028"},"PeriodicalIF":1.5,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12108113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brazilian dental teleconsulting: dentist satisfaction and associated factors.","authors":"Lígia Cristelli Paixão, Mauro Henrique Nogueira Guimarães Abreu, Antônio Paulino Ribeiro-Sobrinho, Renata Castro Martins","doi":"10.1590/1807-3107bor-2025.vol39.027","DOIUrl":"10.1590/1807-3107bor-2025.vol39.027","url":null,"abstract":"<p><p>Teleconsulting consists of communication between professionals about clinical matters using information and communication technologies. Satisfaction is an important outcome in the evaluation of telehealth programs and an indicator of the effectiveness of the services offered. This cross-sectional study evaluated dentist satisfaction with asynchronous dental teleconsulting services offered by the Telehealth Brazil Networks Program and associated factors during 2020, using a secondary database: the Monitoring and Evaluation System of Telehealth Results. The outcome was the satisfaction of the dentist with the response of the teleconsulting session. The other variables collected were the dentist's sex and specialty, the time at which the question and answer of the teleconsulting session were submitted, patient referral, and the dental specialty addressed in the teleconsulting session. The variables were analyzed descriptively using frequency, and binary logistic regression models were used to measure the association between satisfaction and factors related to the dentist and the teleconsulting service. A total of 1,719 dental teleconsulting sessions were conducted. A 26.7% satisfaction level was achieved. Satisfaction with teleconsulting was indicated by the association between professionals declaring that dental teleconsulting \"avoided referrals\" (OR =1.55, 95%CI: 1.17-2.04, p = 0.002) and the teleconsulting sessions in the field of oral medicine (OR = 0.61, 95%CI: 0.43-0.87, p = 0.006). Dentists' satisfaction with asynchronous dental teleconsulting was low. Dentists reporting that teleconsulting avoided patient referrals to other care levels were more likely to be satisfied with the answer from the teleconsultant. Moreover, dentists who submitted oral medicine-related questions were significantly less satisfied with the teleconsulting feedback than those who submitted questions regarding other fields.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e027"},"PeriodicalIF":1.5,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12108114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-05-12eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.056
Tatiana Wannmacher Lepper, Luara Nascimento do Amaral, Ana Laura Ferrares Espinosa, Igor Cavalcante Guedes, Maikel Maciel Rönnau, Natália Batista Daroit, Alex Nogueira Haas, Fernanda Visioli, Manuel Menezes de Oliveira Neto, Pantelis Varvaki Rados
{"title":"Cytopathological quantification of NORs using artificial intelligence to oral cancer screening.","authors":"Tatiana Wannmacher Lepper, Luara Nascimento do Amaral, Ana Laura Ferrares Espinosa, Igor Cavalcante Guedes, Maikel Maciel Rönnau, Natália Batista Daroit, Alex Nogueira Haas, Fernanda Visioli, Manuel Menezes de Oliveira Neto, Pantelis Varvaki Rados","doi":"10.1590/1807-3107bor-2025.vol39.056","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2025.vol39.056","url":null,"abstract":"<p><p>Oral squamous cell carcinoma (OSCC) remains the most prevalent neoplasm of the head and neck. In recent decades, the incidence and prevalence of OSCC have not significantly changed, highlighting the critical need to develop and implement new risk assessment measures. The present study aimed to define argyrophilic proteins of the nucleolar organizer region (AgNOR) cut-off risk points by oral exfoliative cytological smears comparing specialized humans with a convolutional neural network (CNN) system AgNOR Slide-Image Examiner. This study included four experimental groups: control, exposure to carcinogens (alcohol and tobacco), oral potentially malignant disorders, and OSCC. In the first phase, 50 cells were used for AgNOR quantification. In the second phase, AgNOR quantification was established in an automated manner using an AgNOR System - Slide Examiner (captured - bounding-boxed - CNN analysis). In phase 1, the cut-off point for considering a smear as suspicious was established at 3.69 AgNORs/nucleus with sensitivity of 86%, specificity of 93%, and accuracy of 90%. In phase 2, the analysis of the intraclass correlation coefficient of AgNORs attributed to the system and human was 0.896 (95% confidence interval = 0.875-0.915; p < 0.0001), and this quantification with the CNN was 20 min compared to 67 h, considering human analysis. The AgNOR Slide-Image Examiner successfully differentiated the nuclei and accurately quantified the number of NORs in oral cytological smears. The cut-off risk point of 3.69 AgNOR/nucleus indicates a suspicious sample may contribute to improvements in oral cancer screening.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e056"},"PeriodicalIF":1.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12074076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-05-12eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.042
Evelin Carine Alves Silva, Jéssica Arielli Pradelli, Guilherme Ferreira da Silva, Paulo Sérgio Cerri, Mario Tanomaru-Filho, Juliane Maria Guerreiro-Tanomaru
{"title":"Biocompatibility and bioactivity of bioceramic sealers containing 1% cetrimide.","authors":"Evelin Carine Alves Silva, Jéssica Arielli Pradelli, Guilherme Ferreira da Silva, Paulo Sérgio Cerri, Mario Tanomaru-Filho, Juliane Maria Guerreiro-Tanomaru","doi":"10.1590/1807-3107bor-2025.vol39.042","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2025.vol39.042","url":null,"abstract":"","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e042"},"PeriodicalIF":1.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12074077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-05-12eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.055
Auristhela Martinez Acevedo, Ana Leticia Andries E Arantes, Lilian Maria de Moraes Andrade, Eliane Rodrigues de Faria, Michele Pereira Netto, Renata Maria Souza Oliveira, Ana Paula Carlos Cândido, Isabel Cristina Gonçalves Leite
{"title":"Is there an association between body image and self-rated oral health in a sample of Brazilian adolescents?","authors":"Auristhela Martinez Acevedo, Ana Leticia Andries E Arantes, Lilian Maria de Moraes Andrade, Eliane Rodrigues de Faria, Michele Pereira Netto, Renata Maria Souza Oliveira, Ana Paula Carlos Cândido, Isabel Cristina Gonçalves Leite","doi":"10.1590/1807-3107bor-2025.vol39.055","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2025.vol39.055","url":null,"abstract":"<p><p>The aim of this study was to evaluate the association of body image perception and self-assessment of oral health with other associated factors in a sample of Brazilian adolescents. This cross-sectional study involved a total of 281 adolescents aged 14 to 19 years enrolled in 29 public schools from May 2021 to December 2023 in the urban area of Juiz de Fora, state of Minas Gerais, Brazil. The total enrollment of 9,502 participants in the first stage of the study () was considered for sample size calculation. The prevalence of negative self-assessment of oral health in the adolescent population was estimated at 18%, with a standard error of 1%, a 95% confidence interval, and a 20% loss to follow-up. Participants completed a questionnaire via the Google Forms platform, which gathered information on their socioeconomic status, self-perception of body image, self-assessment of oral health, and self-esteem. Bivariate analysis and logistic regression models were used to evaluate the associations between variables. Variables with p < 0.10 in the bivariate analysis were included in the logistic regression model. Variables with p < 0.05 were retained in the final model. The final logistic regression model revealed that adolescents with a higher socioeconomic status rated their oral health as excellent or good. Additionally, those who reported not living with their parents and had a low level of self-esteem had a poor oral health self-assessment. Adolescents' perception of their body image was not associated with oral health self-assessment. On the other hand, socioeconomic factors, family structure, and self-esteem influenced adolescents' oral health self-assessment.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e055"},"PeriodicalIF":1.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12074074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-05-12eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.053
Julia Arruda Batista, Bruno Wakayama, Rayara Nogueira de Freitas, Gabriela Alice Fiais, Antonio Hernandes Chaves-Neto, Tânia Adas Saliba, Artênio José Isper Garbin, Clea Adas Saliba Garbin
{"title":"Impact of oral conditions on salivary biochemical parameters in individuals with substance use disorder: a cross-sectional study.","authors":"Julia Arruda Batista, Bruno Wakayama, Rayara Nogueira de Freitas, Gabriela Alice Fiais, Antonio Hernandes Chaves-Neto, Tânia Adas Saliba, Artênio José Isper Garbin, Clea Adas Saliba Garbin","doi":"10.1590/1807-3107bor-2025.vol39.053","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2025.vol39.053","url":null,"abstract":"<p><p>This study aimed to investigate oral conditions and their impact on salivary biochemical parameters in institutionalized individuals with and without substance use disorder. This was an epidemiological, cross-sectional, and clinical study. It included two groups, institutionalized individuals with substance use disorder (SUD group) and without substance use disorder (control group), each consisting of 60 participants. Salivary samples were analyzed for various parameters, while oral conditions were assessed using the DMFT index, community periodontal index, clinical attachment loss index, and need for prosthesis. Statistical analysis included the Mann-Whitney U test, t-tests, and correlation analysis (p ≤ 0.050). The SUD group showed a higher need for dental prostheses (p < 0.001) and more pronounced dental erosion (p < 0.001). This group also exhibited elevated DMFT indices, with significant associations in sextants with calculus (p = 0.010), periodontal pockets (p < 0.001), and attachment loss of 12 mm or more (p = 0.036). Regarding salivary parameters, the SUD group had high cortisol levels and significant correlations between uric acid and bleeding sextants (p = 0.024), salivary amylase and decayed teeth (p = 0.002), cortisol and the DMFT index (p = 0.045), and cortisol and the absence of DMFT (p = 0.042). In conclusion, individuals in the SUD group exhibited worse oral conditions than did those in the control group, suggesting a relationship between drug addiction and increased cortisol, uric acid, and salivary amylase levels.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e053"},"PeriodicalIF":1.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12074075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-05-12eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.052
Lauren Frenzel Schuch, Laura Borges Kirschnick, Vivian Petersen Wagner, Vanessa Rodrigues Velho, Gabriela Sauer Llantada, Marco Antonio Trevizani Martins, Márcia Martins Marques, Antonio Luiz Barbosa Pinheiro, Jean Nunes Dos Santos, Alan Roger Santos-Silva, Cesar Augusto Migliorati, Manoela Domingues Martins
{"title":"Shedding light on Brazil's contribution to photobiomodulation research in oral medicine: a bibliometric study.","authors":"Lauren Frenzel Schuch, Laura Borges Kirschnick, Vivian Petersen Wagner, Vanessa Rodrigues Velho, Gabriela Sauer Llantada, Marco Antonio Trevizani Martins, Márcia Martins Marques, Antonio Luiz Barbosa Pinheiro, Jean Nunes Dos Santos, Alan Roger Santos-Silva, Cesar Augusto Migliorati, Manoela Domingues Martins","doi":"10.1590/1807-3107bor-2025.vol39.052","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2025.vol39.052","url":null,"abstract":"<p><p>The aim of this study was to verify the role of Brazilian researchers in publications related to photobiomodulation (PBM) in the field of oral medicine. We examined ten years from 2012 to 2022 across 16 journals. Our analysis included scientific publications with a Brazilian author either in the first or last position and publications from international collaborations. The search yielded 43,525 publications. After examining titles and abstracts, 269 studies were categorized as having a specific emphasis on PBM in oral medicine, of which 147 (54.6%) were undertaken by research groups based in Brazil. The citations ranged from 1 to 149 (an average of 31 per manuscript). The male-to-female ratio of first and last author was 1:2 and 1:1.4, respectively. Brazilian involvement in the field of PBM was significant, with a marked focus on basic research, clinical applications, and technological advances. Our results also underscore the remarkable participation of female researchers in pivotal roles. Brazilian publications positively impacted healthcare worldwide using PBM in oral medicine, as evidenced by the substantial number of articles published and the citations of these articles received.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e052"},"PeriodicalIF":1.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12074078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}