Brazilian oral research最新文献

Orofacial antinociceptive activity of codeine-associated geraniol in mice: a controlled triple-blind study. 可待因相关的香叶醇在小鼠口腔中的抗痛觉活性：一项三盲对照研究。

IF 1.5 4区医学

Brazilian oral research Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.1590/1807-3107bor-2024.vol38.0071

Ana Paula Lopes Nunes, Humberto Hugo Nunes de Andrade, Danielle da Nóbrega Alves, Gleycyelly Rodrigues Araújo, Mirian Graciela da Silva Stiebbe Salvadori, Reinaldo Nóbrega de Almeida, Ricardo Dias de Castro

{"title":"Orofacial antinociceptive activity of codeine-associated geraniol in mice: a controlled triple-blind study.","authors":"Ana Paula Lopes Nunes, Humberto Hugo Nunes de Andrade, Danielle da Nóbrega Alves, Gleycyelly Rodrigues Araújo, Mirian Graciela da Silva Stiebbe Salvadori, Reinaldo Nóbrega de Almeida, Ricardo Dias de Castro","doi":"10.1590/1807-3107bor-2024.vol38.0071","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0071","url":null,"abstract":"This is a nonclinical, controlled, and triple-blind study to investigate the effects of codeine-associated geraniol on the modulation of orofacial nociception and its potential central nervous system depressing effect in an animal model. The orofacial antinociceptive activity of geraniol in combination with codeine was assessed through the following tests: (i) formalin-induced pain, (ii) glutamate-induced pain, and (iii) capsaicin-induced pain. Six animals were equally distributed into six groups and received the following treatments, given intraperitoneally (i.p.) 30 minutes before the experiments: a) geraniol/codeine 50/30 mg/kg; b) geraniol/codeine 50/15 mg/kg; c) geraniol/codeine 50/7.5 mg/kg; d) geraniol 50 mg/kg; e) codeine 30 mg/kg (positive control); or f) 0.9% sodium chloride (negative control). We performed pain behavior analysis after the injection of formalin (20 µL, 20%), glutamate (20 µL, 25 µM), and capsaicin (20 µL, 2.5 µg) into the paranasal region. Rubbing time of the paranasal region by the hind or front paw was used as a parameter. In the neurogenic phase of the formalin test, the geraniol/codeine at 50/7.5 mg/kg was able to promote the maximum antinociceptive effect, reducing nociception by 71.9% (p < 0.0001). In the inflammatory phase of the formalin test, geraniol/codeine at 50/30 mg/kg significantly reduced orofacial nociception (p < 0.005). In the glutamate test, geraniol/codeine at 50/30 mg/kg reduced the rubbing time by 54.2% and reduced nociception in the capsaicin test by 66.7% (p < 0.005). Geraniol alone or in combination does not promote nonspecific depressing effects on the central nervous system. Based on our findings, we suggest the possible synergy between geraniol and codeine in the modulation of orofacial pain.","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the factors driving higher interactions in false amber necklace posts on Facebook. 探索推动 Facebook 上假琥珀项链帖子互动性提高的因素。

IF 1.5 4区医学

Brazilian oral research Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.1590/1807-3107bor-2024.vol38.0067

Olívia Santana Jorge, Mariana Olímpio Dos Santos Remiro, Matheus Lotto, Thiago Cruvinel

{"title":"Exploring the factors driving higher interactions in false amber necklace posts on Facebook.","authors":"Olívia Santana Jorge, Mariana Olímpio Dos Santos Remiro, Matheus Lotto, Thiago Cruvinel","doi":"10.1590/1807-3107bor-2024.vol38.0067","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0067","url":null,"abstract":"The consumption and sharing of information on social media contribute to the circulation of false health content. In this sense, popular belief-driven posts recommending the use of amber necklaces to prevent symptoms of teething can be easily found on social media, even when they offer health risks for children. Accordingly, this study aimed to characterize posts in Portuguese by identifying message-based factors associated with higher user interactions of Facebook. A total of 500 Facebook posts published in Portuguese between August 2016 and August 2021 were retrieved by CrowdTangle, and analyzed quantitatively according to time of publication, total user interaction, and post overperforming score, and then qualitatively by two independent investigators, according to motivation, authors' profiles, and sentiment. The data were evaluated by descriptive analysis, Mann-Whitney U test, chi-square test, and multiple logistic regression models regarding interaction metrics. The posts were published predominantly by commercial profiles, with social, psychological, and financial motivations, and expressed positive sentiment. Furthermore, time of publication (OR=2.65), regular user profiles (OR=3.30), and neutral/negative sentiment (OR=2.76) were associated positively with total interactions, whereas only time of publication was associated with post overperforming scores (OR=1.65). In conclusion, Facebook posts promoting efficacy of amber necklaces in managing teething symptoms are primarily created by commercial profiles with vested interests in marketing the product. The key factors that contribute to the success of posts containing false information about amber necklaces on Facebook can be identified by considering the author's profile, sentiment, and time of publication.","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Do SOD2 and SOD3 gene polymorphisms impact the oral health-related quality of life in Para athletes? SOD2 和 SOD3 基因多态性会影响残疾人运动员与口腔健康相关的生活质量吗？

IF 1.5 4区医学

Brazilian oral research Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.1590/1807-3107bor-2024.vol38.0074

Anna Carolina Jesus Silveira, Ludmila Silva Guimarães, Rodrigo VON Held, Erlange Borges da Silva, Flavia Maia Silveira, Zair Candido Oliveira Neto, Rafaela Scariot, Ciro Winckler, Erika Calvano Küchler, João Armando Brancher, Lívia Azeredo Alves Antunes, Leonardo Santos Antunes

{"title":"Do SOD2 and SOD3 gene polymorphisms impact the oral health-related quality of life in Para athletes?","authors":"Anna Carolina Jesus Silveira, Ludmila Silva Guimarães, Rodrigo VON Held, Erlange Borges da Silva, Flavia Maia Silveira, Zair Candido Oliveira Neto, Rafaela Scariot, Ciro Winckler, Erika Calvano Küchler, João Armando Brancher, Lívia Azeredo Alves Antunes, Leonardo Santos Antunes","doi":"10.1590/1807-3107bor-2024.vol38.0074","DOIUrl":"10.1590/1807-3107bor-2024.vol38.0074","url":null,"abstract":"The aim of this study was to evaluate whether polymorphisms in SOD2 and SOD3 genes modulate the oral health-related quality of life (OHRQoL) of Para athletes with dental caries experience. The cross-sectional study included 264 Para athletes (143 in athletics, 61 in weightlifting and 60 in swimming). A trained and calibrated team recorded the decayed, missing and filled teeth index (DMFT). The Brazilian version of the Oral Health Impact Profile (OHIP-14) was used to measure OHRQoL. Genomic DNA was extracted from the athletes' saliva, and genetic polymorphisms in the SOD2 (rs5746136 and rs10370) and SOD3 (rs2855262 and rs13306703) genes were analyzed by real-time polymerase chain reaction. Univariate and multivariate analyses were performed. A multivariate General Linear Model analysis, adjusted for sex, revealed that the SOD3 gene polymorphism (rs2855262) had a significant effect on the psychological disability domain [codominant (p = 0.045) and recessive (p=0.038) models]. The SOD2 gene polymorphism (rs5746136) had a significant effect on the total OHIP-14 score [dominant model (p = 0.038)] and the psychological discomfort [dominant model (p = 0.034)] and physical disability [codominant model (p=0.037)] domains. Presence of the SOD2 rs10370 polymorphism led to statistical differences in the total score [codominant (p = 0.026) and dominant (p = 0.023) models] and the handicap domain scores [codominant (p = 0.027) and dominant (p = 0.032) models]. Polymorphisms of the SOD2 and SOD3 genes may be important biomarkers of OHRQoL in Para athletes with dental caries experience.","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Randomized trial of dentists' understanding: treatment benefit in absolute numbers vs relative risk reduction. 关于牙医理解的随机试验：绝对数量与相对风险降低的治疗效益。

IF 1.5 4区医学

Brazilian oral research Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.1590/1807-3107bor-2024.vol38.0070

Paulo Nadanovsky, Branca Heloisa de Oliveira, Ronaldo Lira-Junior, Ana Paula Pires Dos Santos

{"title":"Randomized trial of dentists' understanding: treatment benefit in absolute numbers vs relative risk reduction.","authors":"Paulo Nadanovsky, Branca Heloisa de Oliveira, Ronaldo Lira-Junior, Ana Paula Pires Dos Santos","doi":"10.1590/1807-3107bor-2024.vol38.0070","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0070","url":null,"abstract":"This study aimed to assess whether dentists correctly understand the benefit of a dental treatment when it is presented using absolute numbers or relative risk reduction (RRR). This parallel-group randomized controlled trial recruited dentists from 3 postgraduate courses in Rio de Janeiro, Brazil. Participants received, in sequentially numbered sealed opaque envelopes, the description of a hypothetical scenario of the benefit (avoidance of multiple tooth loss) of nonsurgical periodontal treatment without or with antibiotics. Treatment benefit was presented in 2 different formats: absolute numbers or RRR. Dentists were given 10 minutes to read the treatment scenario and answer 5 questions. The final sample for analysis included 101 dentists. When asked to estimate the number of patients out of 100 who would avoid multiple tooth loss without antibiotics, 17 dentists (33%) in the absolute numbers group and 12 (25%) in the RRR group provided the correct response (p = 0.39). Regarding treatment with antibiotics, 26 dentists (50%) in the absolute numbers group and 14 (29%) in the RRR group provided the correct response (p = 0.04). Only 16 dentists (31%) in the absolute numbers group and 12 (25%) in the RRR group gave correct answers for both questions (p = 0.51). Most dentists did not correctly understand the benefit of the treatment, irrespective of the format it was presented. Slightly more dentists correctly understood the benefit of the treatment when it was presented as absolute numbers than as RRR.","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral leukoplakia and erythroplakia in young patients: a southern Brazilian multicenter study. 年轻患者的口腔白斑和红斑：巴西南部的一项多中心研究。

IF 1.5 4区医学

Brazilian oral research Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.1590/1807-3107bor-2024.vol38.0069

Alini Cardoso Soares, Ana Paula Neutzling Gomes, Camila Barcellos Calderipe, Fernanda Gonçalves Salum, Karen Cherubini, Manoela Domingues Martins, Lauren Frenzel Schuch, Laura Borges Kirschnick, Lucas Guimarães Abreu, Alan Roger Santos-Silva, Ana Carolina Uchoa Vasconcelos

{"title":"Oral leukoplakia and erythroplakia in young patients: a southern Brazilian multicenter study.","authors":"Alini Cardoso Soares, Ana Paula Neutzling Gomes, Camila Barcellos Calderipe, Fernanda Gonçalves Salum, Karen Cherubini, Manoela Domingues Martins, Lauren Frenzel Schuch, Laura Borges Kirschnick, Lucas Guimarães Abreu, Alan Roger Santos-Silva, Ana Carolina Uchoa Vasconcelos","doi":"10.1590/1807-3107bor-2024.vol38.0069","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0069","url":null,"abstract":"The objective of the present study was to investigate the frequency of oral leukoplakia and oral erythroplakia among young patients from three Brazilian reference centers in Oral and Maxillofacial Pathology. A retrospective study was carried out from 2011 to 2021 on 861 patients diagnosed with oral leukoplakia and oral erythroplakia. Demographic and clinicopathological data were evaluated. Fisher's exact test was used to evaluate the association among sex, age, anatomical location, and histopathological diagnosis. A total of 83 (9.64%) cases involved young patients (aged <40 years). Among these, biopsy records were included in 31 (37.34%) cases, all of which received a clinical diagnosis of oral leukoplakia. Seventeen (54.84%) patients were female, mostly in their fourth decade of life (n = 22/70.97%), and their mean age at diagnosis was 32.61(± 5.21) years. Among informed cases, seven (22.58%) patients were smokers. The lateral border of the tongue (n = 9/29.03%) was the most affected site. In 13 (41.94%) cases, oral leukoplakias showed a homogeneous appearance. The mean size of the lesions was 1.47 cm (0.2-3.0 cm) and the mean time of disease progression was 64.37 (± 65.90) months. The histopathological analysis showed that 11 cases (35.48%) exhibited some degree of epithelial dysplasia. Acanthosis and/or hyperkeratosis were observed in 20 cases (64.52%). No significant associations were observed between sex and anatomical location, age and anatomical location, nor between sex and histological diagnosis (p > 0.05). Oral leukoplakia and oral erythroplakia are uncommon diseases in young patients. In this population, oral leukoplakia shows a slight predilection for women aged between 30 and 39 years.","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physicochemical properties and antibiofilm activity of mineral trioxide aggregate associated with farnesol. 与法尼醇有关的三氧化二铝矿物聚合体的理化特性和抗生物膜活性。

IF 1.5 4区医学

Brazilian oral research Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.1590/1807-3107bor-2024.vol38.0066

Gabriela Mariana Castro-Núñez, Mário Tanomaru-Filho, Gisselle Moraima Chávez-Andrade, Fernanda Ferrari Esteves Torres, Roberta Bosso-Martelo, Juliane Maria Guerreiro-Tanomaru

{"title":"Physicochemical properties and antibiofilm activity of mineral trioxide aggregate associated with farnesol.","authors":"Gabriela Mariana Castro-Núñez, Mário Tanomaru-Filho, Gisselle Moraima Chávez-Andrade, Fernanda Ferrari Esteves Torres, Roberta Bosso-Martelo, Juliane Maria Guerreiro-Tanomaru","doi":"10.1590/1807-3107bor-2024.vol38.0066","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0066","url":null,"abstract":"This study assessed the physicochemical and antibiofilm properties of white mineral trioxide aggregate (MTA) associated with 1 or 2% of farnesol. Setting time was evaluated based on ISO 6876/2012. Radiopacity was evaluated by radiographic analysis. pH was assessed after time intervals of 1, 3, 7, 14, 21, and 28 days. Solubility (% mass loss) and volumetric change (by micro-CT) of the cements were evaluated after immersion in distilled water. The presence of voids inside the materials was assessed by using micro-CT. Antibiofilm activity against Enterococcus faecalis was evaluated by crystal violet assay and the modified direct contact test performed with biofilm previously formed on bovine root dentin for 14 days. Data were submitted to ANOVA/Tukey tests with 5% significance level. The incorporation of farnesol into MTA increased its setting time, but decreased its solubility at 30 days and its volumetric loss in all periods (p < 0.05). Radiopacity and solubility after 7 days were similar among the materials (p > 0.05). The association of farnesol showed the highest pH value after 1 and 3 days (p < 0.05). The association of farnesol with MTA promoted a decrease in the presence of voids, and increased the antimicrobial activity on biofilm biomass of E. faecalis (p < 0.05). In conclusion, the addition of farnesol can be suggested to improve the antimicrobial properties and the consistency of MTA.","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of polymerization shrinkage stress and cuspal strain in natural and typodont teeth. 评估天然牙齿和矫正牙齿的聚合收缩应力和牙尖应变。

IF 1.5 4区医学

Brazilian oral research Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.1590/1807-3107bor-2024.vol38.0061

Luiza Santos Cardoso, Amanda Alves de Oliveira, Gabrielly D'Paula Muniz Barbosa, Maria Luisa Prazeres Ribeiro, Tainah Costa Firmiano, Crisnicaw Veríssimo

{"title":"Evaluation of polymerization shrinkage stress and cuspal strain in natural and typodont teeth.","authors":"Luiza Santos Cardoso, Amanda Alves de Oliveira, Gabrielly D'Paula Muniz Barbosa, Maria Luisa Prazeres Ribeiro, Tainah Costa Firmiano, Crisnicaw Veríssimo","doi":"10.1590/1807-3107bor-2024.vol38.0061","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0061","url":null,"abstract":"To evaluate the polymerization shrinkage stress and cuspal strain (CS) generated in an artificial (typodont) and in a natural tooth using different resin composites. Twenty artificial and 20 extracted natural molars were selected. Each tooth was prepared with a 4x4 mm MOD cavity. The natural and typodont teeth were divided into four experimental groups (n=10), according to the resin composite used: Filtek Z100 (3M Oral Care) and Beautifil II LS (Shofu Dental). The cavities were filled using two horizontal increments and the CS (µS) was measured by the strain gauge method. Samples were sectioned into stick-shaped specimens and the bond strength (BS) (MPa) was evaluated using a microtensile BS test. Shrinkage stress and CS were analyzed using 3D finite element analysis. No difference was found between the type of teeth for the CS as shown by the pooled averages: Natural tooth: 541.2 A; Typodont model: 591.4 A. Filtek Z100 CS values were higher than those obtained for Beautifil II LS, regardless of the type of teeth. No statistical difference was found for the BS data. Adhesive failures were more prevalent (79.9%). High shrinkage stress values were observed for Filtek Z100 resin, regardless of tooth type. The CS of typodont teeth showed a shrinkage stress effect, generated during restoration, equivalent to that of natural teeth.","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of streptozotocin-induced diabetes on experimental masseter pain in rats. 链脲佐菌素诱导的糖尿病对实验性大鼠咀嚼肌疼痛的影响

IF 1.5 4区医学

Brazilian oral research Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.1590/1807-3107bor-2024.vol38.0073

Yuri Martins Costa, Clarissa Carolina Fernandes Herculiani, Flávia Fonseca Carvalho Soares, Michelle de Campos Soriani Azevedo, Paulo César Rodrigues Conti, Thiago José Dionísio, Gabriela de Moraes Oliveira, Flávio Augusto Cardoso de Faria, Carlos Ferreira Santos, Gustavo Pompermaier Garlet, Leonardo Rigoldi Bonjardim

{"title":"Impact of streptozotocin-induced diabetes on experimental masseter pain in rats.","authors":"Yuri Martins Costa, Clarissa Carolina Fernandes Herculiani, Flávia Fonseca Carvalho Soares, Michelle de Campos Soriani Azevedo, Paulo César Rodrigues Conti, Thiago José Dionísio, Gabriela de Moraes Oliveira, Flávio Augusto Cardoso de Faria, Carlos Ferreira Santos, Gustavo Pompermaier Garlet, Leonardo Rigoldi Bonjardim","doi":"10.1590/1807-3107bor-2024.vol38.0073","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0073","url":null,"abstract":"This study aimed to assess the influence of streptozotocin (STZ)-induced diabetes on the nociceptive behavior evoked by the injection of hypertonic saline (HS) into the masseter muscle of rats. Forty male rats were equally divided into four groups: a) isotonic saline control, which received 0.9% isotonic saline (IS), (Ctrl-IS); b) hypertonic saline control, which received 5% HS (Ctrl-HS); c) STZ-induced diabetic, which received IS, (STZ-IS); d) STZ-induced diabetic, which received HS (STZ-HS). Experimental diabetes was induced by a single intraperitoneal injection of STZ at dose of 60 mg/kg dissolved in 0.1 M citrate buffer, and 100 μL of HS or IS were injected into the left masseter to measure the nociceptive behavior. Later on, muscle RNA was extracted to measure the relative expression of the following cytokines: cyclooxygenase-2 (COX-2), tumor necrosis factor (TNF-α), and interleukins (IL)-1β, -2, -6, and -10. One-way analysis of variance (ANOVA) was applied to the data (p < 0.050). We observed a main effect of group on the nociceptive response (ANOVA: F = 11.60, p < 0.001), where the Ctrl-HS group presented the highest response (p < 0.001). However, nociceptive response was similar among the Ctrl-IS, STZ-IS, and STZ-HS group (p > 0.050). In addition, the highest relative gene expression of TNF-α and IL-6 was found in the masseter of control rats following experimental muscle pain (p < 0.050). In conclusion, the loss of somatosensory function can be observed in deep orofacial tissues of STZ-induced diabetic rats.","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Top 100 most-cited papers on diabetes mellitus in Dentistry: a bibliometric study. 关于牙科糖尿病的 100 篇最常被引用的论文：文献计量学研究。

IF 1.5 4区医学

Brazilian oral research Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.1590/1807-3107bor-2024.vol38.0075

Alexandre Henrique Dos Reis-Prado, Kiani Dos Santos de Paula, Gabriel Pereira Nunes, Lucas Guimarães Abreu, Luciano Tavares Angelo Cintra, Isabella Faria da Cunha Peixoto, Francine Benetti

{"title":"Top 100 most-cited papers on diabetes mellitus in Dentistry: a bibliometric study.","authors":"Alexandre Henrique Dos Reis-Prado, Kiani Dos Santos de Paula, Gabriel Pereira Nunes, Lucas Guimarães Abreu, Luciano Tavares Angelo Cintra, Isabella Faria da Cunha Peixoto, Francine Benetti","doi":"10.1590/1807-3107bor-2024.vol38.0075","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0075","url":null,"abstract":"This study assessed the features of the 100 most-cited papers on diabetes mellitus (DM) in dentistry using bibliometric measures. A search of the most cited papers on DM using journals included in the category \"Dentistry, Oral Surgery and Medicine\" in the Web of Science database up to January 2023 was performed. The complete bibliographic records of the selected papers were exported in plain text or Research Information Systems (RIS) file format. The following bibliometric indicators were collected: title, year, authors, number of citations, mean number of citations, institution, country, continent, study design, journal, impact factor, and keywords. Graphical bibliometric networks were created using the VOSviewer software. The number of citations for the 100 most-cited papers in DM research ranged from 111 to 566. Six papers each had more than 400 citations. Most were observational studies (n = 50) from the United States (USA) (n = 23) and were published in the Journal of Periodontology (30%; n=30). Robert Genco was the most cited author and contributed the most to the top 100 articles (3,653 citations; n = 13). The VOSviewer map of co-authorship showed the existence of clusters in research collaboration. The most prolific institutions were the Universities of Buffalo and Michigan (n = 6 each). \"Diabetes mellitus\" was the most frequent keyword, with 31 occurrences. In conclusion, the most cited studies that investigated the relationship between dentistry and DM were in periodontology. Observational studies, primarily from the USA, have been the most cited thus far.","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of COVID-19 on pediatric dental care in two epicenters: Italy and Brazil. COVID-19 对两个震中地区儿童牙科护理的影响：意大利和巴西。

IF 1.5 4区医学

Brazilian oral research Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.1590/1807-3107bor-2024.vol38.0068

Camilla Karoline de Carvalho Beckman, Valentina Luppieri, Letícia Martins Pereira, Camila Ribeiro Silva, Paula Midori Castelo, Milena Cadenaro, Regina Maria Puppin Rontani, Aline Rogéria Freire de Castilho

{"title":"Impact of COVID-19 on pediatric dental care in two epicenters: Italy and Brazil.","authors":"Camilla Karoline de Carvalho Beckman, Valentina Luppieri, Letícia Martins Pereira, Camila Ribeiro Silva, Paula Midori Castelo, Milena Cadenaro, Regina Maria Puppin Rontani, Aline Rogéria Freire de Castilho","doi":"10.1590/1807-3107bor-2024.vol38.0068","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0068","url":null,"abstract":"The study aimed to compare the adherence of Brazilian and Italian pediatric dentists to the biosafety measures and operative protocols recommended by the health authorities during COVID-19 pandemic and to classify the participants according to their risk of infection. An online questionnaire with 34 questions about sociodemographic and occupational data, dental practice organization, biological risk management, and clinical operative protocols was sent to Brazilian and Italian pediatric dentists using a convenience sampling strategy. Chi-square test and multivariate analysis (two-step cluster) were performed (α = 5%). Of 641 respondents (377 Brazilians and 264 Italians), most were female (94% and 70%, respectively), aged 20-39 years (63%), with over 10 years of professional experience (58% and 49%, respectively). Based on adherence to recommended biosafety measures, participants were classified as \"safer\" (n = 219) or \"less safe\" (n = 422). Adherence to recommended protocols by the majority of participants resulted in low contagion rates (Brazilians = 5%; Italians = 12.5%). Participants with extensive professional experience in the dental setting exhibited a greater tendency to implement multiple adaptations (three or more) in their practice. Most participants (Brazilians = 92%; Italians = 80.7%) adopted the recommended minimal intervention dentistry approaches, with the use of fissure sealants and the use of non-rotary instruments for caries removal the most frequently techniques used among Brazilians (36%) and Italians (66%), respectively. Two different profiles of pediatric dentists were identified based on the biosafety protocols adopted during the pandemic. In addition, changes were implemented in the dental care provided to children, with focus on the minimal intervention dentistry.","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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