{"title":"Investigation of factors influencing sugar consumption in early life: a cross-sectional study.","authors":"Tainá Fontes de Souza, Aline Gama Freitas, Mariana Leonel Martins, Andréa Fonseca-Gonçalves","doi":"10.1590/1807-3107bor-2025.vol39.062","DOIUrl":"10.1590/1807-3107bor-2025.vol39.062","url":null,"abstract":"<p><p>This study evaluated the influence of socioeconomic factors, caregiver characteristics, and early feeding practices on sugar consumption frequency (FSC) during early childhood. Data were collected from dental records of children aged 1 to 5 years old, who were attended at CliBin®, including sex, age, skin color, income level, mother's age and years of education, primary caregiver, prior instructions on caries prevention, type of early feeding practices (breastfeeding/formula/mixed), exclusive breastfeeding (EB) up to 6 months, children's dental care and their consumption of sugar-sweetened beverages (SSB) and cookies/sugar (CS), with frequency classified as: never (2 points), ≤ 3 times/day (1 point) and > 3 times/day (0 points). The lower the median score the higher the FSC. Descriptive analysis, Kruskal-Wallis test, and ANOVA were applied considering p < 0.05. A total of 123 records were included. The children were predominantly male (56.1%), and brown (46.5%), with an average age of 2.1 (± 0.9) years. The mother was the primary caregiver (86.1%), with ≤ 30 years of age (52.0%), < 12 years of education (75.2%), and previously instructed on caries prevention (58.2%). Most children were breastfed (45.5%) for 23.2 (±9.7) months on average, received EB (87.1%), consumed SSB (87.6%) and CS (90.9%) 3 times/day. The total FSC mean score was 1.6 ± 0.9 (95%CI: 1.4-1.7). Children of younger mothers (≤ 30 years) had the lowest FSC scores (1.4 ± 0.9; 95%CI: 1.0-1.6; p=0.01). It was observed that among the factors studied, only mothers in the younger age range influenced high sugar consumption during early childhood.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e062"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-06-02eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.057
Isabella Silveira Savo, Samanta Vicente de Oliveira, Gabriela Banacu de Melo, Celso Lemos, Camila de Barros Gallo
{"title":"Over-the-counter and compounded mouthwashes for radiotherapy-induced xerostomia: a randomized controlled trial.","authors":"Isabella Silveira Savo, Samanta Vicente de Oliveira, Gabriela Banacu de Melo, Celso Lemos, Camila de Barros Gallo","doi":"10.1590/1807-3107bor-2025.vol39.057","DOIUrl":"10.1590/1807-3107bor-2025.vol39.057","url":null,"abstract":"<p><p>Head and neck radiotherapy quantitatively and qualitatively compromises salivary flow, and salivary substitutes have the potential to alleviate the symptoms. This study aims to assess the effectiveness of two salivary substitutes in relieving symptoms of radiotherapy-induced xerostomia through a double-blind randomized controlled trial. Twenty-four patients were selected from a dental oncology clinic and randomly assigned to the over-the-counter or compounded mouthwash group. Each patient was instructed to rinse their oral cavity with the assigned solution three times a day for 30 days. Both participants and researchers were blinded to the product used during the trial. The impact of xerostomia was assessed using a numerical rating scale and validated questionnaires on oral health-related quality of life and xerostomia, administered before and after the intervention and subsequently compared. Both groups exhibited a statistically significant reduction in xerostomia symptoms. The studied salivary substitutes produced transient beneficial effects on complaints of radiotherapy-induced xerostomia.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e057"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors associated with positive perceptions of sealant use on permanent molars among Brazilian dentists.","authors":"Larissa Yumi Ito, Leticia Maíra Wambier, Ana Cláudia Rodrigues Chibinski, Manoelito Ferreira Silva Junior, Denise Stadler Wambier","doi":"10.1590/1807-3107bor-2025.vol39.054","DOIUrl":"10.1590/1807-3107bor-2025.vol39.054","url":null,"abstract":"<p><p>This study aimed to analyze the factors associated with the perception among Brazilian dentists of the preventive or therapeutic use of sealants on permanent molars. A cross-sectional web-based survey was conducted with Brazilian dentists between July and October 2021 to examine their use of social media and gather data regarding sealant-related practices. A structured questionnaire was developed and applied to collect information on participants' professional profiles, clinical indications, materials, techniques, and perceptions of pit and fissure sealants. The study outcomes were the positive perception of sealant use as: (a) a preventive measure, or (b) a therapeutic approach to carious lesions. Responses were dichotomized into positive perception (\"strongly agree\" or \"agree\") and negative perception (\"neither agree nor disagree,\" \"disagree\" or \"strongly disagree\"). Independent variables included sociodemographic, educational, professional, and technical characteristics. Multiple logistic regression models were used to analyze associations (p < 0.05). A total of 2,394 dentists participated in the study, 82.5% of whom had a positive perception of sealants for prevention, and 83.1%, for therapeutic purposes. A greater likelihood of positive perception of preventive sealant use was observed among educators, those employed in public health services, dentists who \"always\" performed sealant application, and those who used resin sealant, glass ionomer cement, or flowable resin. Conversely, professionals working in capital cities had a lower likelihood of a positive perception. Professionals from cities with populations exceeding 500,000 inhabitants, interior areas, or metropolitan regions were less likely to have a positive perception of therapeutic sealant use. However, those who used resin sealants, glass ionomer cement, or flowable resin were more likely to perceive sealants positively. In conclusion, the positive perception of sealant use for prevention was associated with educational, professional, and technical factors, whereas the positive perception of therapeutic use was associated with professional and technical factors.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e054"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-06-02eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.059
Layse de Góis Sena, Maria Davoli Meyer, Mariana Gallante Ricardo, Isaac Jordão de Souza Araújo, Julia Puppin Rontani, Vanessa Arias Pecorari, Elizabeth Ferreira Martinez, Lucas Novaes Teixeira, Francisco Humberto Nociti-Junior, Paulo Noronha Lisboa-Filho, Kamila Rosamilia Kantovitz
{"title":"Effect of titanium dioxide nanotubes incorporated into conventional glass ionomer cement on L. acidophilus.","authors":"Layse de Góis Sena, Maria Davoli Meyer, Mariana Gallante Ricardo, Isaac Jordão de Souza Araújo, Julia Puppin Rontani, Vanessa Arias Pecorari, Elizabeth Ferreira Martinez, Lucas Novaes Teixeira, Francisco Humberto Nociti-Junior, Paulo Noronha Lisboa-Filho, Kamila Rosamilia Kantovitz","doi":"10.1590/1807-3107bor-2025.vol39.059","DOIUrl":"10.1590/1807-3107bor-2025.vol39.059","url":null,"abstract":"<p><p>The present in vitro study evaluated the effect of titanium dioxide nanotubes (nTiO2) incorporated into glass ionomer cement (GIC) on the growth and viability of Lactobacillus acidophilus (L. acidophilus). GIC (Ketac Molar EasyMix® = KM) was added to concentrations of 0%, 3%, 5%, 7% by weight of nTiO2 (20 nm in size). L. acidophilus strains (1x108 CFU/mL) were cultivated on GIC discs with or without the addition of nTiO2 for 1, 3 and 7 days, and the following parameters were evaluated: inhibition zone (mm) (n = 6); cell viability (Live/Dead) (n = 6); cell morphology (SEM) (15 KV, 2000X, n = 3). The data were submitted to ANOVA and the Tukey and Dunnett tests (α = 0.05). Regarding the agar diffusion test, there was no difference between GIC and the groups containing nTiO2 (p > 0.05). As for bacterial viability, the percentage of viable bacteria was lower for GIC+7% nTiO2 (p ≤ 0.05). There was no difference in the percentage of non-viable bacteria (p > 0.05). In addition, the morphology of L. acidophilus did not change in the presence of nTiO2. It can be concluded that the incorporation of titanium dioxide nanotubes into GIC, particularly at 5%, reduced L. acidophilus viability, and might hence interfere negatively with the initial colonization process of the bacterial biofilm.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e059"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-06-02eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.060
Betty Salazar Mayta, Laís Alves Candido, Karla Zancopé, Paulo Cézar Simamoto Júnior, Gustavo Mendonça, Flávio Domingues das Neves
{"title":"Effect of preservation on the mechanical properties of 3D printing resins for occlusal splints.","authors":"Betty Salazar Mayta, Laís Alves Candido, Karla Zancopé, Paulo Cézar Simamoto Júnior, Gustavo Mendonça, Flávio Domingues das Neves","doi":"10.1590/1807-3107bor-2025.vol39.060","DOIUrl":"10.1590/1807-3107bor-2025.vol39.060","url":null,"abstract":"<p><p>This study aims to evaluate the mechanical properties of 3D printing resins for occlusal splints (OS) under different preservation conditions based on sleep duration. The study factors (n = 10) included material types: PriZma 3D Bio Splint (PZ), Cosmos Splint (CS), NightGuard Firm (NGF), and self-polymerizing acrylic resin (control group - CG); preservation: artificial saliva (S), natural water (W), 0.12% chlorhexidine (C), and Corega tabs (CTs); and evaluation times: T0 (24 h after fabrication) and 30 d after exposure. Further, the surface roughness (Ra), Knoop microhardness (KH), three-point flexural strength (FS), and flexural modulus (FM) were analyzed. In terms of the time and material, Tukey's test revealed no significant differences in Ra between the groups at 24 h. After 30 d, PZ showed significantly lower values than the other groups (p < 0.05). For the KH, NGF was significantly higher than that in all groups at 24 h (p < 0.05); after 30 d, the NGF decreased in W and C (p < 0.05), and the NGF and PZ exhibited elevated values in S and CT, respectively. The Kruskal-Wallis test and multiple comparisons showed that the PZ had a higher value at 24 h (p < 0.05). Post 30 d, all 3D-printing resins increased values in CT and S (p < 0.05), and the PZ decreased in the C and W (P < 0.05). Finally, the FM increased under all conditions. The preservation of S and CT partially enhanced the mechanical properties of the OS.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e060"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypomineralized primary teeth and their association with Molar Incisor Hypomineralization: a cross-sectional study.","authors":"Bruna Cordeiro Amarante, Leticia Yumi Arima, Giovanna Bueno Marinho, Ana Carolina Cheron Gentile, Edgard Michel-Crosato, Marcelo Bönecker","doi":"10.1590/1807-3107bor-2025.vol39.063","DOIUrl":"10.1590/1807-3107bor-2025.vol39.063","url":null,"abstract":"<p><p>Environmental and systemic factors play a role in the development of hypomineralization characterized by demarcated opacities. This study aimed to investigate the prevalence, distribution, severity, and etiologic factors associated with hypomineralization in all primary teeth, hypomineralized second primary molars (HSPM) and evaluate its association with Molar Incisor Hypomineralization (MIH). A sample of 2,102 male and female Brazilian children aged 3 to 10 years exhibiting good general health was examined by 30 calibrated dentists using WHO probes and clinical mirrors, using the index proposed by Ghanim et al. Data were collected through clinical examinations and a questionnaire answered by mothers, addressing sociodemographic and prenatal, perinatal, and postnatal factors. Prevalence was assessed by calculating frequency, whereas etiologic factors were evaluated using univariate and multivariate Poisson logistic regression with robust adjustment. In addition, multivariate analysis was conducted using nonparametric resampling with Jacknife adjustment. The overall prevalence of hypomineralization in primary teeth was 18.5%, with second molars affected in 17% and canines in 6.7% of the cases, while other teeth were affected at lower rates. Exclusive breastfeeding for six months showed a protective effect against hypomineralization (p = 0.40). Children with HSPM were five times more likely to develop MIH, regardless of sex (OR: 4.92). Furthermore, lower family income increased the likelihood of MIH. In conclusion, hypomineralization in primary teeth is prevalent, exclusive breastfeeding for six months is associated with a lower prevalence of enamel defects, and children with primary dentition defects are at greater risk for similar conditions in their permanent teeth.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e063"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-06-02eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.058
Dandara Andrade de Santana, Yann Victor Paiva Bastos, Paulo Tambasco de Oliveira, Bruno Cunha Pires, Flávia Caló Aquino Xavier, Águida Cristina Gomes Henriques Leitão, Larissa Abbehusen Couto, André Sampaio Souza, Luciana Maria Pedreira Ramalho, Patrícia Ramos Cury, Jean Nunes Dos Santos
{"title":"Medication-related osteonecrosis of the jaws: a series of 22 cases highlighting their histopathological features.","authors":"Dandara Andrade de Santana, Yann Victor Paiva Bastos, Paulo Tambasco de Oliveira, Bruno Cunha Pires, Flávia Caló Aquino Xavier, Águida Cristina Gomes Henriques Leitão, Larissa Abbehusen Couto, André Sampaio Souza, Luciana Maria Pedreira Ramalho, Patrícia Ramos Cury, Jean Nunes Dos Santos","doi":"10.1590/1807-3107bor-2025.vol39.058","DOIUrl":"10.1590/1807-3107bor-2025.vol39.058","url":null,"abstract":"<p><p>This study aimed to assess the clinicopathological characteristics of medication-related osteonecrosis of the jaw (MRONJ), addressing histopathological features and bone structure. Twenty-two MRONJ patients were retrospectively evaluated for osteonecrosis, osteomyelitis, bacterial colonization, bone resorption, reactive bone, osteon-like structure, lamellar bone, and basophilic lines. Specific staining and fluorescence and polarized light microscopy assessments were also performed. The mandible was significantly more affected by MRONJ. There was a predominance of African-Brazilian women aged sixty and older. Osteomyelitis was present in 82% of patients. Actinomycosis was observed in 36.4% of MRONJ patients. Osteoclasts were absent in MRONJ but bone resorption was often seen. Basophilic lines were observed in more than 80% of the patients. The MRONJ patients exhibited lamellar bone with osteon-like structures. This study provided important insight into MRONJ, demonstrating a diverse histopathological spectrum and infection with Actinomyces and fungi. The condition was characterized by a necrotized lamellar bone structure and more frequently affected the mandible of older women.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e058"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-06-02eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.061
Amanda Garcia Alves Maliza, Renata Maíra de Souza Leal, Bruno Cavalini Cavenago, Murilo Priori Alcalde, Rodrigo Ricci Vivan, Marco Antônio Húngaro Duarte
{"title":"Endodontic retreatment of curved canals using Reciproc, Hyflex CM and Prodesign Duo Hybrid Systems.","authors":"Amanda Garcia Alves Maliza, Renata Maíra de Souza Leal, Bruno Cavalini Cavenago, Murilo Priori Alcalde, Rodrigo Ricci Vivan, Marco Antônio Húngaro Duarte","doi":"10.1590/1807-3107bor-2025.vol39.061","DOIUrl":"10.1590/1807-3107bor-2025.vol39.061","url":null,"abstract":"<p><p>The aim of this ex vivo study was to evaluate the efficacy of the Reciproc, Hyflex CM, and ProDesign Duo Hybrid in the retreatment of mesial root canals with Vertucci Type 4 of mandibular molars with curvatures between 10 and 20 degrees. Forty-five mesial roots of mandibular molars were prepared up to size 25.06 Nickel-Titanium (NiTi) file and filled by the single cone technique. The roots were then divided into 3 groups according to retreatment procedures: Reciproc R25 followed by R40; Hyflex 25.04 followed by 40.04; ProDesign Duo Hybrid 25.06 followed by 40.05. The canals were irrigated with 1 mL 1% sodium hypochlorite, and a final rinse was performed with 5 mL 17% EDTA for 3 minutes. Microcomputed tomography scans were performed in each step of the procedure to evaluate root canal transportation at distances of 2, 4, 6, 8 and 10 mm from the apex and volume of endodontic filling remaining at segments of 1-3, 3-5, and 5-7 mm from the apex. The filling material that was not removed during retreatment was evaluated by confocal laser scanning and the percentage after each procedure was expressed in terms of percentage of the initial root-filling material volume. The time taken to remove the material and re-instrumentation was measured in seconds with a digital chronometer. Statistical analysis was performed with t-paired, ANOVA, Kruskal-Wallis and Friedman tests (p < 0.05). In all groups, sections at 4, 6, 8, and 10 mm from the apex were transported to the danger zone, towards the furcation. However, the section at 2 mm from the apex was transported in opposite direction to the furcation, but no statistically significant differences (p > 0.05) in canal transportation and filling material removal were found between the 3 groups. Filling removal and re-instrumentation took significantly (p < 0.05) less time in the Reciproc group. None of the retreatment techniques completely removed the root fillings. The results suggest that no difference exists between the groups in apical transportation of curved canals. The Reciproc system took less time for filling removal and re-instrumentation and the combination of reciprocating and rotary files in the retreatment of curved canals was as efficient as rotary and reciprocating motion.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e061"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-05-23eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.032
Ana Luiza Peres Baldiotti, Gabrielle Amaral-Freitas, Mariane Carolina Faria Barbosa, Paula Rocha Moreira, Renata de Castro Martins, Renato Assis Machado, Ricardo Della Coletta, Michelle Nascimento Meger, Saul Martins Paiva, Rafaela Scariot, Fernanda de Morais Ferreira
{"title":"Temporomandibular joint disorders, happiness, and COMT, HTR2A and FKBP5 polymorphisms in adolescents: a cross-sectional study.","authors":"Ana Luiza Peres Baldiotti, Gabrielle Amaral-Freitas, Mariane Carolina Faria Barbosa, Paula Rocha Moreira, Renata de Castro Martins, Renato Assis Machado, Ricardo Della Coletta, Michelle Nascimento Meger, Saul Martins Paiva, Rafaela Scariot, Fernanda de Morais Ferreira","doi":"10.1590/1807-3107bor-2025.vol39.032","DOIUrl":"10.1590/1807-3107bor-2025.vol39.032","url":null,"abstract":"<p><p>Temporomandibular joint disorder (TMD) has a multifactorial etiology involving psychological and genetic aspects. This condition commonly begins in adolescence, which is a period of emotional, physical, and psychological maturation. The aim of the present study was to investigate associations between temporomandibular joint (TMJ) disorder and happiness as well as polymorphisms in the COMT, HTR2A, and FKBP5 genes in Brazilian adolescents. A cross-sectional study was conducted with 90 adolescents aged 13 to 18 years. TMD was diagnosed using the RDC/TMD. The Subjective Happiness Scale (SHS) was used to assess happiness. Saliva samples were collected for the analysis of genomic DNA and genotyping of single nucleotide polymorphisms in the COMT (rs165656, rs174675), HTR2A (rs6313, rs4941573), and FKBP5 (rs1360780, rs3800373) genes using real-time PCR (Taqman method). Bivariate, unadjusted, and adjusted binary logistic regression analyses were performed (p < 0.05). Happiness was associated with TMD in the adolescents (OR=1.37; 95%CI: 1.02-1.85; p = 0.037). The rs174675 polymorphism in the COMT gene was significantly associated with TMD (OR = 0.18; 95%CI: 0.04-0.74; p = 0.018). No associations were found between TMD and polymorphisms in HTR2A and FKBP5 genes (p > 0.05). TMD was associated with happiness, as adolescents who considered themselves less happy were more likely to have this disorder. The diagnosis of TMD was also associated with the rs174675 polymorphism in the COMT gene, as the prevalence of the disorder was higher among homozygous C Brazilian adolescents than in heterozygous CT individuals.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e032"},"PeriodicalIF":1.5,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12108116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brazilian oral researchPub Date : 2025-05-23eCollection Date: 2025-01-01DOI: 10.1590/1807-3107bor-2025.vol39.028
Débora Costa Ruiz, Rocharles Cavalcante Fontenele, Amanda Farias-Gomes, Hugo Gaêta-Araujo, Matheus Lima Oliveira, Deborah Queiroz Freitas, Francisco Haiter-Neto
{"title":"Influence of a portable X-ray device in the diagnosis of proximal caries lesions.","authors":"Débora Costa Ruiz, Rocharles Cavalcante Fontenele, Amanda Farias-Gomes, Hugo Gaêta-Araujo, Matheus Lima Oliveira, Deborah Queiroz Freitas, Francisco Haiter-Neto","doi":"10.1590/1807-3107bor-2025.vol39.028","DOIUrl":"10.1590/1807-3107bor-2025.vol39.028","url":null,"abstract":"<p><p>This study aimed to evaluate the influence of a portable X-ray device on the diagnosis of proximal caries lesions. For that, radiographs of 40 human teeth with white spots or color changes in enamel and/or dentin were acquired using the Eagle X-ray portable device (Alliage, São Paulo, Brazil) set at 2.5 mA, 60 kVp and an exposure time of 0.5 s (1.25 mAs). Then, new radiographs of the teeth were acquired using the Focus X-ray wall-mounted device (Instrumentarium, Tuusula, Finland) set at 7 mA, 70 kVp, and exposure time of 0.16 s (1.12 mAs). Five oral and maxillofacial radiologists individually assessed the radiographs. Area under the receiver operating characteristic curve (AUC), sensitivity, and specificity were calculated from the responses of the five examiners and compared between the devices tested using Student's t test. Significance level was set at 5% (α = 0.05). The weighted Kappa index evaluated the intra- and inter-examiner agreements for caries lesions diagnosis. The use of a portable X-ray device did not influence on AUC, sensitivity and specificity metrics for the diagnosis of caries lesions (p > 0.05). The intra- and inter-examiner agreements for the caries lesions diagnosis ranged from substantial to almost perfect (0.646-0.859) and moderate to substantial (0.491-0.617), respectively. The diagnostic accuracy for detecting proximal caries lesions is not impaired when using a portable X-ray device.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"39 ","pages":"e028"},"PeriodicalIF":1.5,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12108113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}