Brazilian oral research最新文献

{"title":"Erratum.","authors":"","doi":"10.1590/1807-3107bor-2023.vol37.0119.erratum","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0119.erratum","url":null,"abstract":"<p><p>[This corrects the article doi: 10.1590/1807-3107bor-2023.vol37.0119].</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"37 suppl 1","pages":"e119err"},"PeriodicalIF":1.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physicochemical properties of silicate tricalcium-based cement for use as pulp capping or repair material.","authors":"Suyane Maria Luna-Cruz, Bernardo Almeida Aguiar, Pierre Basílio Almeida Fechine, Marco Antônio Húngaro Duarte, Bruno Carvalho de Vasconcelos, Juliano Sartori Mendonça","doi":"10.1590/1807-3107bor-2024.vol38.0136","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0136","url":null,"abstract":"<p><p>This study evaluated some physicochemical properties of an experimental tricalcium silicate-based cement (ETSC) indicated for use as pulp capping or endodontic repair material; Biodentine (BD) and White MTA-Angelus (MTA) cements served as comparators. Setting time, radiopacity, sorption, and solubility were determined according to ISO 6876/2012 and compressive strength according to ISO 9917-1/2019. pH and calcium ion release capacity were also assessed. Data were analyzed using ANOVA and Tukey tests or Kruskal-Wallis and Dunn tests with α = 0.05. BD (15') and ETSC (17.3') exhibited the shortest initial setting times, with BD (29') having the shortest final setting time; MTA showed longer times in both analyses (p < 0.05). ETSC and MTA showed the highest radiopacity (6.1 mm Al and 5.7 mm Al), while BD showed the lowest (3.0 mm Al) (p < 0.05). BD exhibited the highest compressive strength (88.8 MPa), significantly higher than the others (p < 0.05). BD presented the lowest values for sorption, 0.12% (24 h) and 0.48% (28 d), which differed significantly from MTA (p < 0.05). The lowest values for solubility were shown for ETSC, 0.26% (24 h), and BD, 0.52% (28 d), which differed significantly from MTA (p<0.05). ETSC showed the highest pH throughout all periods; significant differences were observed for MTA (3 h) and BD (24 h) (p<0.05). In the Ca2+ analysis, BD provided the highest values in all periods; differences were only significant compared to MTA (3h/24h) (p <0 .05). Considering the study conditions, it can be concluded that ETSC exhibited characteristics similar or better properties than the commercial cements tested, except for compressive strength.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"38 ","pages":"e136"},"PeriodicalIF":1.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143055858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crystallization by microwave energy: Effects on the survival probability of lithia-based glass ceramics.","authors":"Pedro Santos Diamantino, Camila da Silva Rodrigues, Ana Beatriz Gomes de Carvalho, João Paulo Mendes Tribst, Hilton Riquieri, Nathália de Carvalho Ramos, Diogo Miguel da Costa Cabecinha Pacheco Viegas, Edmara Tatiely Pedroso Bergamo, Estevam Augusto Bonfante, Guilherme de Siqueira Ferreira Anzaloni Saavedra","doi":"10.1590/1807-3107BOR-2024.vol38.0127","DOIUrl":"https://doi.org/10.1590/1807-3107BOR-2024.vol38.0127","url":null,"abstract":"<p><p>This study evaluated the survival probabilities of two lithia-based glass-ceramics after final crystallization in a microwave furnace using conventional crystallization as a reference. Disc-shaped samples of a lithium silicate (LS, Celtra Duo) and a lithium disilicate (LD, e.max CAD) were prepared and divided into two groups according to the crystallization method (n = 30): microwave (M) or conventional furnaces (C). The biaxial flexural strength test was used to determine the fatigue test profile and its parameters. Then, specimens were submitted to an accelerated life test (step stress) using three profile levels - mild, moderate, and aggressive - varying the load increments and the number of cycles until fracture (4 Hz). Survival data were used to calculate Weibull's beta (β) value and reliability of the assigned missions. Scanning electron microscopy was employed to analyze surface morphology, fracture characteristics, and failure patterns. Beta (β) values for the LS-C, LS-M, LD-C, and LD-M groups were 2.65, 0.25, 0.62, and 0.3, respectively. Similar reliability was observed in all groups after 50,000 cycles at 100 and 150 Mpa. At 200 Mpa, the crystallization method did not affect the reliability within LS or LD. However, LD showed greater reliability than LS when crystallized by microwave energy. Thus, microwave energy can be suggested as an alternative to the process of conventional lithia-based glass-ceramics crystallization without damaging their survival probabilities.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"38 ","pages":"e127"},"PeriodicalIF":1.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceptions of research integrity and open science practices: a survey of Brazilian dental researchers.","authors":"Jaisson Cenci, Marina Christ Franco, Tatiana Pereira-Cenci, Marcos Britto Correa, Lucas Helal, David Moher, Lex Bouter, Marie Charlotte Huysmans, Maximiliano Sérgio Cenci","doi":"10.1590/1807-3107bor-2024.vol38.0135","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0135","url":null,"abstract":"<p><p>The objective of this study was to evaluate Brazilian dental researchers' perceptions of research integrity and open science practices, as well as their perceptions of the way researchers are evaluated for promotion, hiring, and receiving grants. In a self-administered online survey, the respondents were presented with 3 questions on researcher evaluation in Brazil. Additionally, for 25 academic activities or characteristics, researchers rated their perceived importance for a) career advancement, b) science advancement, c) personal satisfaction, and d) social impact. The questionnaire was sent to a total of 2,179 dental researchers working in graduate programs in dentistry in Brazil. Multilevel regressions were performed to statistically confirm the differences between the predefined subgroups. Three hundred and fifty-five (16%) researchers completed the survey. Most respondents (96.1%) considered the current evaluation system to be flawed and indicated the need for improvement. Non-traditional activities were considered more important than traditional ones for science advancement (p < 0.01), and social impact (p < 0.01), whereas traditional activities were perceived to be more important only for career advancement (p < 0.01). Although Brazilian dental researchers recognize the value of open science and research integrity practices for science advancement and impact on society, they perceive that the current evaluation system emphasizes traditional activities, such as publishing many papers in well-recognized journals as criteria for advancing their careers.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"38 ","pages":"e135"},"PeriodicalIF":1.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1590/1807-3107bor-2024.vol38.0091err","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0091err","url":null,"abstract":"<p><p>[This corrects the article doi: 10.1590/1807-3107bor-2024.vol38.0091].</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"38 ","pages":"e091err"},"PeriodicalIF":1.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of clinicopathological characteristics in young and elderly patients with oral squamous cell carcinoma: a retrospective study in Northeastern Brazil.","authors":"Pedro Augusto Bulhões Curioso, Ivan José Correia Neto, Lucas Lacerda de Souza, Edilmar de Moura Santos, Alan Roger Santos-Silva, Pablo Agustin Vargas, Marcio Ajudarte Lopes","doi":"10.1590/1807-3107bor-2024.vol38.0138","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0138","url":null,"abstract":"<p><p>The aim of this study was to perform a clinicopathological analysis of oral squamous cell carcinoma (OSCC) in young patients from the northeast of Brazil and compare with elderly individuals. This retrospective study reviewed 104 OSCC cases from 2000 to 2015, focusing on patients under 40 and over 60 at diagnosis. Forty-two patients under 40 years old (40.38%) and 62 patients over 60 years old (59.62%) were analyzed using descriptive statistics, chi-square, and Fisher's exact tests for clinicopathological factors, and Kaplan-Meier and Cox models for survival and prognostics. Most of the patients were male, with younger patients having lower rates of smoking (45.24%) and alcohol use (28.57%) compared to older patients (82.30% and 40.32%, respectively). Younger patients had a higher prevalence of tongue cancer and smaller tumors but faced more compromised surgical margins, perineural invasion, local recurrence, regional metastasis, distant metastasis, and second primary tumors. Statistical findings highlighted age-related differences in clinicopathological features and indicated that despite similar overall survival rates, younger patients had a poorer prognosis related to local recurrences, regional recurrences, and second tumors. Perineural invasion emerged as an independent prognostic factor. The study suggests that younger OSCC patients require personalized management strategies to address their higher risk of adverse outcomes, with an emphasis on the prognostic significance of perineural invasion.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"38 ","pages":"e138"},"PeriodicalIF":1.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental appointments in the primary health care setting for users with toothache: a longitudinal analysis.","authors":"Fabiano Costa Diniz, Maria Inês Barreiros Senna, Érika Talita Silva, Lígia de Assis Silva, Gizelton Pereira Alencar, Elisa Lopes Pinheiro, Loliza Luiz Figueiredo Houri Chalub, Raquel Conceição Ferreira","doi":"10.1590/1807-3107bor-2024.vol38.0134","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0134","url":null,"abstract":"<p><p>This study aimed to estimate the morbidity associated with toothache treated in the primary health care (PHC) setting, stratified by the population size of Brazilian municipalities, from 2018 to 2022. This longitudinal ecological study was based on public national data from routine public dental service utilization records within the Health Information System for Primary Care. These data were employed to compute the rate of dental appointments for users with toothache (per 1,000 users) within each municipality throughout 15 four-month periods (P1-2018 to P3-2022), classified by population size. We integrated the databases for population size, denominator, and numerators. A longitudinal data regression model was used to estimate the four-monthly variation before and after P2-2020. Records from 5,332 municipalities (95.72%) were analyzed. The average rate of dental appointments for users with toothache (per 1,000 users) ranged from 9.65 (P2-2020) to 27.24 (P1-2018). Throughout the period, larger municipalities showed the lowest rates. Before P2-2020, the average rate in municipalities with >100,000 inhabitants fell by an average of 20.56% every four months, higher than the 7.25% variation in municipalities with < 5,000 inhabitants. After P2-2020, the rate in municipalities with < 5,000 inhabitants rose by 2.27%, a value lower than the variation in larger municipalities. The rates of dental appointments for users with toothache in the PHC setting indicate the persistent severity of dental conditions among public health service users, with variations across different regions of the country. The COVID-19 pandemic has affected the rate of dental appointments for users with toothache, underscoring the need for dental services to enhance their adaptability and responsiveness to such crises.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"38 ","pages":"e134"},"PeriodicalIF":1.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fiberglass posts reduced fractures in endodontically treated teeth restored with veneers: a case-control study.","authors":"Fábio Herrmann Coelho-DE-Souza, Andréa de Azevedo Brito Conceição, Maria Carolina Guilherme Erhardt, Luciano de Souza Gonçalves","doi":"10.1590/1807-3107bor-2024.vol38.0137","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0137","url":null,"abstract":"<p><p>This study aimed to evaluate the effects of fiberglass posts on fracture behavior in endodontically treated teeth (ETT) restored with composite veneers. Adult patients who had endodontically treated anterior teeth restored with composite veneers, with or without fiberglass posts, were divided into the case (with fractured teeth) and control (without fractured teeth) groups. All fracture patterns were sorted by a 6-point scoring system: 0, no fracture; 1, veneer buccal fracture; 2, incisal edge fracture; 3, coronal middle-third fracture; 4, coronal cervical fracture; 5, coronal and root fracture; and 6, root fracture. The odds ratio was calculated concerning the outcome (fracture) and exposed factor (post presence). Fracture patterns were analyzed by the Mann-Whitney and Fisher exact tests, with a significance level of 95%. Of the 89 ETT restored with composite veneers (31 with posts; 58 without posts), 30 were fractured. The odds ratio revealed a reduction in fracture risk to 34% compared with ETT without posts. Teeth without posts fractured more frequently, showing more complex fracture patterns. In conclusion, fiberglass posts decreased the risk of fractures in ETT restored with composite veneers.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"38 ","pages":"e137"},"PeriodicalIF":1.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral cancer immunology: state of the art and future perspectives.","authors":"Fábio Muradás Girardi, Lauren Frenzel Schuch, Manoela Domingues Martins","doi":"10.1590/1807-3107bor-2024.vol38.0129","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0129","url":null,"abstract":"<p><p>Oral cancer is a multifactorial disease involving genetic, epigenetic, and environmental factors. The literature indicates that inflammatory cells at the advancing front of the tumor induce a host immune response, preventing the spread of the tumor. However, cancer cells adopt various continued strategies to circumvent this immune surveillance. The complexity of immune mechanisms suggests that there must be virtually individual patterns of anti-tumor immune responses. Due to this important interaction of cancer with the immune system, the objective of the present study was to provide an up-to-date overview of immuno-oncology focused on oral cancer, summarizing the basic immunology, the classic risk factors, immunotherapy, and future treatment and prognostic perspectives.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"38 ","pages":"e129"},"PeriodicalIF":1.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermogenic preworkout supplement induces alveolar bone loss in a rat model of tooth movement via RANK/RANKL/OPG pathway.","authors":"Gurgiane Rodrigues Gurgel Cavalcante, Mariana Cabral Moreno, Flavia Queiroz Pirih, Vanessa de Paula Soares, Éricka Janine Dantas da Silveira, José Sandro Pereira da Silva, Hallissa Simplício Gomes Pereira, Katherine Pennington Klein, Maria Luiza Diniz de Sousa Lopes, Aurigena Antunes de Araujo, Agnes Andrade Martins, Ruthinéia Diógenes Alves Uchôa Lins","doi":"10.1590/1807-3107bor-2024.vol38.0131","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2024.vol38.0131","url":null,"abstract":"<p><p>The aim of this study was to investigate the effect of thermogenic supplementation on the bone tissue of rats subjected to orthodontic movement. A total of 38 male Wistar rats underwent orthodontic movement of the left permanent maxillary first molars for 21 days. The rats were assigned to three groups: Control group: water; Thermogenic 1: C4 Beta Pump thermogenic; or Thermogenic 2: PRE-HD/Pre-workout. Micro-computed tomography (micro-CT) was used to investigate the dynamic changes in the microstructure of alveolar bone during orthodontic tooth movement in rats. Histopathologic analysis was performed by hematoxylin and eosin (H&E) staining, whereas tartrate-resistant acid phosphatase (TRAP) was employed for osteoclast count. Maxillary tissue was collected and evaluated by immunohistochemistry for receptor activator of NF-κB (RANK), receptor activator of NF-κB ligand (RANKL), and osteoprotegerin (OPG). The Thermogenic 2 group exhibited a significantly lower percentage of bone volume fraction (BV/TV) (68.21% ± 17.70%) compared to the control (86.84% + 12.91%) and Thermogenic 1 groups (86.84% + 15.94%) (p < 0.05). The control group had a significantly higher mean orthodontic movement in the mesial direction (0.2143 mm + 0.1513 mm) than the Thermogenic 2 group (0.0420 mm + 0.05215 mm) (p < 0.05). The Thermogenic 2 and Thermogenic 1 groups showed a stronger immunostaining for RANKL when compared to the control group (p < 0.05). The supplementation used in the Thermogenic 2 group (PRE-HD/Pre-workout) induced alveolar bone loss in rats subjected to orthodontic movement, which can be related to the regulation of the RANK/RANKL/OPG signaling pathway. This suggests the influence of thermogenic supplements on bone metabolism seems to depend on their composition.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"38 ","pages":"e131"},"PeriodicalIF":1.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}