Brazilian oral research最新文献

{"title":"Prognostic factors in pediatric head and neck rhabdomyosarcoma: a 30-year retrospective study in Brazil.","authors":"Deisi Romitti Maglia, Bruna do Amaral Ferreira Souza, Taiane Berguemaier de Lima, Lauro José Gregianin, Fernanda Visioli","doi":"10.1590/1807-3107bor-2026.vol40.052","DOIUrl":"10.1590/1807-3107bor-2026.vol40.052","url":null,"abstract":"<p><p>This study aimed to evaluate the survival outcomes of pediatric patients with head and neck (HN) rhabdomyosarcoma (RMS) treated at a reference center in Brazil, comparing them with those of patients with non-head and neck (NHN) RMS. Additionally, it sought to identify the clinical-pathological variables, histological subtypes, and antineoplastic therapy regimens that significantly influence patient prognosis. The study included RMS patients treated between 1990 and 2022. Statistical analyses comprised t-tests, chi-square tests, Kaplan-Meier survival analysis, and Cox regression for overall survival (OS), disease-free survival (DFS), and event-free survival (EFS). A total of 64 patients (60.9% male) were included, with head and neck tumors being the most common presentation. Prognostic factors associated with OS included age ≥ 10 years, intermediate-risk classification, tumor relapse, and surgery. DFS was significantly influenced by age ≥10 years and high-risk classification, while EFS was associated with lesion size, histological subtype, and radiotherapy. In conclusion, anatomical site was not a significant prognostic factor. Age and risk classification significantly influenced OS and DFS, while histological subtype emerged as an independent factor for EFS. This study, conducted at a reference center in Latin America with a 30-year history of care, provides clinically relevant insights by identifying specific prognostic factors for RMS in Brazilian pediatric patients. These findings enable comparisons with international data and contribute to planning health interventions.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"40 ","pages":"e052"},"PeriodicalIF":1.4,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13502293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Humanization of AI-generated abstracts in oral radiology: Role of chatbots and dedicated platforms.","authors":"Caio Alencar-Palha, Thaís Ocampo, Thaísa Pinheiro Silva, Deborah Queiroz Freitas, Frederico Sampaio Neves, Matheus Lima Oliveira","doi":"10.1590/1807-3107bor-2026.vol40.067","DOIUrl":"10.1590/1807-3107bor-2026.vol40.067","url":null,"abstract":"<p><p>The rise of generative artificial intelligence (AI) in scientific writing has prompted the development of platforms designed to \"humanize\" AI-generated text by rephrasing content to reduce its detectability as machine-generated. This study aimed to evaluate the performance of chatbots and dedicated platforms in humanizing AI-generated abstracts. Thirty high-impact scientific articles published in dentomaxillofacial radiology journals were selected. The Methodology and Results sections of each abstract were used to prompt two chatbots-ChatGPT and Gemini-to generate complete abstracts. These AI-generated abstracts were then humanized using the same chatbots along with two dedicated platforms: HumanizeAI and StealthWriter. The percentage of AI-generated content was determined for all abstracts (n = 330), including the original human-written abstracts, using GPTZero. AI detection rates were compared using two-way analysis of variance followed by Tukey's post hoc test (α = 0.05). The results showed that original abstracts and AI-generated abstracts humanized by HumanizeAI and StealthWriter exhibited significantly lower GPTZero detection rates (p < 0.05), whereas abstracts generated or humanized by chatbots showed significantly higher detection rates (p < 0.05). In conclusion, chatbot-generated scientific abstracts humanized by dedicated platforms exhibit low AI detection rates, whereas those humanized by chatbots exhibit considerably higher detection levels. Educators must prepare students with critical appraisal skills to identify AI-generated content and uphold academic integrity, ensuring that AI serves as a complementary tool rather than a means of misrepresentation.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"40 ","pages":"e067"},"PeriodicalIF":1.4,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13502292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital era in oral rehabilitation: a scoping review of trends and implications for clinical practice.","authors":"Adriana da Fonte Porto Carreiro, Anne Kaline Claudino Ribeiro, Gülce Çakmak, Walter Yu Hang Lam, Wei-Shao Lin, Ji-Man Park, Murali Srinivasan, Manabu Kanazawa, Amirali Zandinejad, Burak Yilmaz","doi":"10.1590/1807-3107bor-2026.vol40suppl1066","DOIUrl":"10.1590/1807-3107bor-2026.vol40suppl1066","url":null,"abstract":"<p><p>This scoping review mapped the evidence on the clinical applicability and implications of digital workflows for fixed and removable full-arch rehabilitation in completely edentulous patients, focusing on workflow-related operational parameters and clinician-reported outcomes. This review was conducted in accordance with the PRISMA-ScR and was registered on the Open Science Framework. The research question was \"What is the current evidence on digital workflows for full-arch rehabilitations and their implications for clinical practice?\". A search was conducted in PubMed/MEDLINE, Web of Science, Scopus, Cochrane Library, and Embase, supplemented by grey literature and reference screening. The inclusion criteria were clinical studies and reviews focusing on the clinical implications of workflow-related performance indicators and the clinician's perceptions, considering the digital workflow. A descriptive analysis was conducted in terms of clinical application and key findings regarding accuracy, time-efficiency, cost-effectiveness, and clinician satisfaction. A total of 40 studies were included. The implant-level impressions demonstrated values for 3D linear deviations within clinically acceptable thresholds (up to 200 μm) and traditional methods remained feasible for tissue impressions due to the highest discrepancies found in the peripheral regions. The digital workflow was time- and cost-saving, ranging from 27.17% to 75.10% and 9.21% to 39.49%, respectively. The digital workflow was accurate for implant-level impressions. Evidence suggests limitations in peripheral and movable mucosa capture; however, certain protocols may improve reliability, and conventional methods remain important in specific clinical contexts. Moreover, it's time- and cost-efficient for interventions in completely edentulous patients, but the evidence remains scarce and inconclusive for clinician satisfaction.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"40 suppl 1","pages":"e066"},"PeriodicalIF":1.4,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13502517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neighborhood factors and use of dental services among young adults in Southern Brazil: a 5-year cohort study.","authors":"Jocelaine Vieira Vione, Letícia Donato Comim, Nathália Costa de Castro, Giovana Rodrigues Silva, Julio Eduardo do Amaral Zenkner, Luana Severo Alves","doi":"10.1590/1807-3107bor-2026.vol40.068","DOIUrl":"10.1590/1807-3107bor-2026.vol40.068","url":null,"abstract":"<p><p>This prospective cohort study assessed the influence of contextual variables of the residential neighborhood on the pattern of preventive use of dental services among young adults from southern Brazil. The study was linked to a population-based cross-sectional survey carried out in 2018 that evaluated the oral health conditions of adolescents aged 15-19 years from Santa Maria, southern Brazil (n = 1,197). After a mean (± SD) period of 5 (± 0.5) years, 570 individuals were reassessed (response rate: 47.6%). Questionnaires collected sociodemographic characteristics, dental service use (including the reason for the last visit), and participants' addresses. The outcome was the last dental visit for prevention, defined as positive responses at both baseline and follow-up. The main predictor variables were contextual neighborhood variables (mean income, percentage of literate inhabitants, percentage of residences with tap water, paved streets, sewerage system, and public lighting). Unadjusted and adjusted multilevel Poisson regression models were used to estimate relative risk (RR) and 95% confidence intervals (CI). Approximately one-quarter of participants reported that their last dental visit was for prevention (n = 151, 26.5%). After controlling for individual-level variables, participants living in neighborhoods with above-median income (RR=1.27; 95%CI: 1.04-1.55; p = 0.02), higher literacy levels (RR = 1.31; 95%CI:1.02-1.68; p = 0.03), greater proportion of paved streets (RR =1.28; 95%CI: 1.01-1.63; p = 0.04), or greater sewerage coverage (RR = 1.40; 95%CI: 1.05-1.85; p = 0.02) were more likely to report their last dental visit for prevention. In conclusion, this cohort study demonstrated that neighborhood-level variables influenced the pattern of preventive dental visits among young adults in southern Brazil.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"40 ","pages":"e068"},"PeriodicalIF":1.4,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13502294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peri-implantitis progression and modulating factors: evidence synthesis and implications for clinical management.","authors":"Cátia Sufia Alves Freire de Andrade, João Pedro Dos Santos Silva, Gildenilson Oliveira Júnior, Bruna Egumi Nagay, Jamil Awad Shibli, João Gabriel Silva Souza, Valentim Adelino Ricardo Barão","doi":"10.1590/1807-3107bor-2026.vol40suppl1065","DOIUrl":"10.1590/1807-3107bor-2026.vol40suppl1065","url":null,"abstract":"<p><p>Peri-implantitis is a biofilm-related disease characterized by inflammation and tissue damage in the peri-implant mucosa, along with progressive loss of supporting bone. Although triggered by a polymicrobial biofilm, disease progression is influenced by factors beyond microbial buildup. This thorough review explores factors that may promote peri-implant disease progression, focusing on interactions among biofilm dynamics, local conditions, patient-related factors, and material-related characteristics. Evidence suggests that biofilm maturation, ecological imbalance, and ongoing inflammatory response are key drivers of disease progression. Locally, microbial shifts, iatrogenic conditions, and reduced cleanability seem to facilitate microbial buildup and hinder maintenance. Patient factors such as a history of periodontitis, smoking, and poorly controlled diabetes are most consistently linked to poorer peri-implant outcomes, while genetic susceptibility remains suggested but not confirmed. Material properties, including surface topography, roughness, chemistry, wettability, corrosion behavior, and particle release, may influence microbial colonization and host responses, though their independent clinical significance is less certain. Overall, current research points to a multifactorial model of peri-implant disease progression, though much of the evidence is based on observational studies with substantial heterogeneity, limiting the ability to draw definitive conclusions. A comprehensive understanding of microbial, biological, prosthetic, systemic, and material factors is crucial for accurate risk assessment, prevention, and personalized management of peri-implantitis.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"40 suppl 1","pages":"e065"},"PeriodicalIF":1.4,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13502516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative efficacy of violet light, bleaching gel, or their combination, in in-office bleaching: a systematic review and network meta-analysis.","authors":"Michael Willian Favoreto, Renata Maria Oleniki Terra, Camila Mendes Camargo, Bianca Maran, Vanessa Cavalli, Ana Cláudia Chibinski, Alessandro Dourado Loguercio, Alessandra Reis","doi":"10.1590/1807-3107bor-2026.vol40.056","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2026.vol40.056","url":null,"abstract":"<p><p>This systematic review and network meta-analysis aimed to determine whether the use of violet light alone (VIOL) or its combination with bleaching gels (BGVIOL) results in superior bleaching efficacy compared to bleaching gel alone (BG). Randomized clinical trials (RCTs) were identified through searches in PubMed, Cochrane Central, LILACS/BBO, SCOPUS, Web of Science, EMBASE, and gray literature sources in March, 2025. Eligible RCTs compared in-office bleaching using BG, or VIOL, or BGVIOL. The Cochrane risk of bias tool was used to evaluate the risk of bias (RoB 2.0) of the eligible RCTs. A random-effects Bayesian mixed treatment comparison model evaluated color change (ΔE*ab and ΔSGU/final SGU), and risk and intensity of tooth sensitivity (TS). Ranking probabilities were evaluated using the surface under the cumulative ranking curve, and the certainty of evidence was appraised following the Grading of Recommendations Assessment, Development, and Evaluation approach. Out of 4,963 records, 17 RCTs were included, 11 of which had a high RoB. Analysis of ΔE*ab revealed significant mean differences (MD) and 95% credibility interval (95%Crl) for the full dataset for BGVIOL vs. BG (MD = 3.13; 95%CrI: 1.33 to 4.97), but not with the subset of data that excluded studies with high RoB (MD = 2.36; 95%CrI: -0.74 to 5.34). Color change in ΔSGU did not differ among groups. VIOL showed the lowest risk and intensity of TS. Color change achieved with BG and BGVIOL was higher than that obtained with VIOL. VIOL yielded lower risk and intensity of TS. The certainty of the evidence supporting these findings is low or very low.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"40 ","pages":"e056"},"PeriodicalIF":1.4,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13475733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial proteomic profile of early colonizers on the acquired pellicle of patients with head and neck cancer.","authors":"Talita Mendes Oliveira Ventura, Júlia Thomazini Pereira, Ramilli Maria de Oliveira, Larissa Tercília Grizzo Thomassian, Nathalia Regina Ribeiro, Even Akemi Taira, Vinícius Taioqui Pelá, Aline Dionizio Valle, Cássia Maria Fisher Rubira, Paulo Sérgio da Silva Santos, Marília Afonso Rabelo Buzalaf","doi":"10.1590/1807-3107bor-2026.vol40.055","DOIUrl":"10.1590/1807-3107bor-2026.vol40.055","url":null,"abstract":"<p><p>Radiotherapy is the cornerstone of head and neck cancer (HNC) treatment, but it has been frequently associated with changes in the acquired enamel pellicle (AEP), potentially affecting the early stages of dental biofilm formation. Thus, this study aimed to characterize the bacterial proteomic profiles of early colonizers adhering to the AEP in patients with HNC undergoing radiotherapy, with emphasis on radiation-induced changes that may influence oral biofilm development and oral health outcomes. AEP samples were collected from nine patients with HNC before radiotherapy (BRT), during radiotherapy (DRT), and after radiotherapy (ART), as well as from nine orally healthy individuals. Pellicles were obtained 120 min after formation and analyzed by shotgun label-free proteomics using nanoLC-ESI-MS/MS. Protein expression levels were compared between groups using the t test (p < 0.05). AEP showed elevated levels of bacterial proteins predominantly attributed to Actinomyces, mainly associated with DNA binding, chromatin organization, and glucose metabolism. The bacterial proteomic profile shifted markedly DRT, with exclusive detection of proteins involved in carbohydrate transport and metabolism, oxidative stress response, and protein folding, including several ATP-binding cassette transporters and glycolytic enzymes. Proteins related to stress tolerance, transcriptional regulation, and secretion systems were detected ART, many of them associated with bacterial species commonly linked to periodontal diseases, such as Tannerella and Oribacterium. Notably, Cysteine synthase was identified exclusively BRT in all comparisons, suggesting its potential as a biomarker. These findings indicate that radiotherapy induces dynamic changes in the AEP bacterial proteome, potentially favoring dysbiotic biofilm development and increasing susceptibility to oral diseases in patients with HNC.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"40 ","pages":"e055"},"PeriodicalIF":1.4,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13450022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148721046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro and in vivo biocompatibility and bioactivity of bioceramic repair materials.","authors":"Lara Cancella de Arantes, Alexandre Henrique Dos Reis-Prado, Karina Sampaio Caiaffa, Pedro Augusto Monteiro Delgado, Sabrina de Castro Oliveira, Francielen Oliveira Fonseca, Warley Luciano Fonseca Tavares, Cristiane Duque, Luciano Tavares Angelo Cintra, Carlos Roberto Emerenciano Bueno, Ricardo Alves de Mesquita, Gustavo Batista de Menezes, Antônio Paulino Ribeiro-Sobrinho, Francine Benetti","doi":"10.1590/1807-3107bor-2026.vol40.053","DOIUrl":"10.1590/1807-3107bor-2026.vol40.053","url":null,"abstract":"<p><p>This study aimed to evaluate the in vitro cytotoxicity and bioactivity, and the in vivo biocompatibility, collagen maturation, and bioactivity, of PBS Cimmo HP and Bio-C Repair Ion+ in comparison with white MTA-Angelus. Osteoblast-like cell viability was assessed using the Alamar Blue assay, while bioactivity was assessed by alkaline phosphatase (ALP) activity and Alizarin Red staining. For the in vivo analysis, polyethylene tubes containing the materials or empty tubes (control) were implanted in the dorsum of mice. After 7 and 30 days (n = 8), the animals were euthanised and the specimens were processed for haematoxylin-eosin, Picrosirius Red, von Kossa (VK), and polarised light (PL) analyses. Data were statistically analysed (p < 0.05). Most materials extracts were cytocompatible (P > 0.05), except for the PBS Cimmo HP 1:4 extract at 48-h (p < 0.05). All materials showed increased ALP activity (p < 0.05). Mineralized nodules were significantly present in most material extracts (p < 0.05), except in the undiluted PBS Cimmo HP extract and in the white MTA-Angelus 1:4 extract. At 7 days, PBS Cimmo HP induced moderate-to-severe inflammation, whereas the other groups induced moderate inflammation (p > 0.05). At 30 days, all groups showed reduced inflammation (p > 0.05). Overall, the fibrous capsule was thick at 7 days and thin at 30 days. At 7 days, the control and PBS Cimmo HP groups showed a greater presence of immature collagen (p < 0.05); at 30 days, more mature collagen was observed in all groups (p > 0.05). The materials exhibited positivity for VK or PL in both periods. In conclusion, PBS Cimmo HP and Bio-C Repair Ion+ were cytocompatible and biocompatible, and demonstrated bioactivity and collagen maturation similar to those of white MTA-Angelus.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"40 ","pages":"e053"},"PeriodicalIF":1.4,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13450023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148720177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is bruxism associated with the use of screen devices in children and adolescents? A systematic review.","authors":"Ayah Qassem Shqair, Matheus Dos Santos Fernandez, Cacilda Castelo Branco Lima, Marília Leão Goettems, Francisco Wilker Mustafa Gomes Muniz","doi":"10.1590/1807-3107bor-2026.vol40.054","DOIUrl":"10.1590/1807-3107bor-2026.vol40.054","url":null,"abstract":"<p><p>This systematic review summarized findings on the association between screen time and bruxism in children and adolescents (PROSPERO- CRD42023429775). Two researchers conducted the search and selection of studies, extracted the data, and analyzed the risk of bias. The quality of the evidence was assessed using the GRADE tool. Five databases were screened on September 25th, 2025. Studies exploring the association between bruxism and the use of screen devices in individuals aged 0-18 were included, considering different and valid study designs, screen devices, and methods of detection of bruxism behavior with or without circadian distinction. Qualitative data synthesis was performed. Eleven cross-sectional and two cohort studies were included. Eight studies found an association between bruxism and the use of screen devices in children and adolescents, while five studies did not find a significant association. In conclusion, an association between screen use or duration and bruxism in children and adolescents cannot be established. Although some studies reported positive associations for awake, sleep, and unspecified bruxism, particularly in research evaluating longer daily screen time or indicators of problematic digital use, the certainty of the evidence was very low. Further well-designed longitudinal studies should be conducted to broaden the overview of this association.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"40 ","pages":"e054"},"PeriodicalIF":1.4,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13450021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148720566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of remote diagnosis of oral mucositis in children and adolescents with cancer using a mobile App: a pilot study.","authors":"Thayana Maria Navarro Ribeiro de Lima Martins, Paula Maria Maracajá Bezerra, Fábio Gomes Dos Santos, Eliane Batista de Medeiros Serpa, Ana Maria Gondim Valença, Simone Alves de Sousa","doi":"10.1590/1807-3107bor-2026.vol40.044","DOIUrl":"10.1590/1807-3107bor-2026.vol40.044","url":null,"abstract":"<p><p>Remote examinations have become increasingly common in Dentistry, especially with the use of applications. This preliminary cross-sectional study evaluated the accuracy of remote examination of oral mucositis (OM) and severe oral mucositis (SOM) using photos obtained through the Telepediatric Dentistry in Oncology (TON) application, comparing its results with the in-person clinical examination (gold standard). A total of 21 pediatric patients (13 boys, 8 girls; mean age 9.05 ± 3.46 years) undergoing chemotherapy were examined, totaling 28 in-person examinations and 224 photographic images assessed remotely by four calibrated dentists (Kappa > 0.7). The photos covered eight oral cavity sites (lips, right and left buccal mucosa, tongue dorsum, lateral tongue, palate, and floor of the mouth) and were analyzed for the presence or absence of OM and SOM. Among the 28 examinations, 11 presented OM and 3 presented SOM. The remote examination identified all positive cases (sensitivity 100%; 95%CI: 0.741-1), while specificity was 59% for OM, reflecting the occurrence of false positives, especially in the lips and buccal mucosa. Agreement between remote examiners and the gold standard ranged from 0.17 to 1.0, depending on the region and evaluator, being higher in the tongue dorsum, lateral tongue, and floor of the mouth. The results indicate that remote examination via TON may be feasible and has the ability to detect OM and SOM, potentially serving as a complementary tool in dental monitoring of children and adolescents undergoing oncology treatment, particularly when in-person examination is not possible.</p>","PeriodicalId":9240,"journal":{"name":"Brazilian oral research","volume":"40 ","pages":"e044"},"PeriodicalIF":1.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13426465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148683377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}