Bioscience, Biotechnology, and Biochemistry最新文献_第2页

Insight on flavinylation and functioning factor in Type B succinate dehydrogenase from Gram-positive bacteria. 革兰氏阳性菌B型琥珀酸脱氢酶黄烷化及功能因子的研究。

IF 1.4 4区生物学

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-05-21 DOI: 10.1093/bbb/zbaf026

Yusuke Shiota, Tomoyuki Kosaka

引用次数: 0

Small daily doses of orange heirloom ("Moonglow") tomatoes dose-dependently increase plasma and liver lycopene concentrations in rats. 每日小剂量的橙色传家宝（' moonlow '）番茄剂量依赖性地增加大鼠血浆和肝脏番茄红素浓度。

IF 1.4 4区生物学

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-05-21 DOI: 10.1093/bbb/zbaf027

Umani S Walallawita, Frances M Wolber, Ayelet Ziv-Gal, Marlena C Kruger, Julian A Heyes

引用次数: 0

Impact of a water-soluble soy extract on inflammation and gut microbiota in physiologically aged mice. 水溶性大豆提取物对生理衰老小鼠炎症和肠道微生物群的影响。

IF 1.4 4区生物学

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-05-21 DOI: 10.1093/bbb/zbaf032

Kenji Watanabe, Yuka Kamei, Miki Igarashi, Shuichi Shibuya, Takahiko Shimizu, Ikuo Kimura, Mitsuo Maruyama

{"title":"Impact of a water-soluble soy extract on inflammation and gut microbiota in physiologically aged mice.","authors":"Kenji Watanabe, Yuka Kamei, Miki Igarashi, Shuichi Shibuya, Takahiko Shimizu, Ikuo Kimura, Mitsuo Maruyama","doi":"10.1093/bbb/zbaf032","DOIUrl":"10.1093/bbb/zbaf032","url":null,"abstract":"Soy isoflavones are involved deeply in our diet as beneficial to health. It is known to have anti-inflammatory and antioxidant effects and also to be effective in alleviating various lifestyle diseases, as well as the maintenance of endocrine function, especially with age-related diseases such as osteoporosis. Here we investigated the impact of age-dependent changes with the intestinal microbiota in physiologically aged C57BL/6 N by free drinking water with soluble soybean-derived isoflavone glycosides (SIFs) for 4 weeks. Consequently, Akkermansia muciniphila (A. muciniphila) species represented an age-dependent increase with SIF treatment, subsequently, generally age-dependent decreased goblet cells are retained in the large intestine. These results invoke that SIF plays a beneficial role in intestinal barrier function to maintain large intestine homeostasis. Interestingly, we also revealed that SIF had an alleviating effect on age-dependent bone loss. Taken together, SIF has a fruitful effect on the intestinal environment and the maintenance of homeostasis in physiological aging.","PeriodicalId":9175,"journal":{"name":"Bioscience, Biotechnology, and Biochemistry","volume":" ","pages":"884-893"},"PeriodicalIF":1.4,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between the biological activities and the chemical structures of conidendrin-related compounds: (-)-β-conidendrin inhibits degranulation of RBL-2H3 cells. 百合素相关化合物的生物活性与化学结构的关系：(-)-β-百合素抑制RBL-2H3细胞的脱粒。

IF 1.4 4区生物学

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-05-21 DOI: 10.1093/bbb/zbaf039

Momoko Ishida, Iria Matsubara, Satoshi Yamauchi, Kosuke Nishi, Takuya Sugahara

{"title":"Correlation between the biological activities and the chemical structures of conidendrin-related compounds: (-)-β-conidendrin inhibits degranulation of RBL-2H3 cells.","authors":"Momoko Ishida, Iria Matsubara, Satoshi Yamauchi, Kosuke Nishi, Takuya Sugahara","doi":"10.1093/bbb/zbaf039","DOIUrl":"10.1093/bbb/zbaf039","url":null,"abstract":"Conidendrin, a metabolite of lariciresinol (a lignan in dietary plants), has 8 stereoisomers with 3 asymmetric carbon atoms. However, the relationship between the chemical structure and biological activity of these stereoisomers remains unclear. Since strong cytotoxicity against rat basophilic cell line RBL-2H3 cells has been observed in 4 stereoisomers, the degranulation inhibitory effect of the other conidendrin isomers possessing no cytotoxicity was investigated. Significant degranulation inhibitory effect was observed on all 4 stereoisomers especially on (-)-β-conidendrin, suggesting that conidendrin exhibits stereospecific cytotoxic and degranulation inhibitory activities, and (-)-β-conidendrin is the most structurally effective isomer on antidegranulation. Additionally, (-)-β-conidendrin inhibited the antigen-induced increase in intracellular Ca2+ concentration and phosphorylation levels of Syk, PLCγ, and Akt, indicating that (-)-β-conidendrin inhibits Ca2+ influx into cells by downregulating the Syk/PLCγ and PI3K/Akt signaling pathways, thereby suppressing degranulation. Our findings suggest that conidendrin may be useful as an antiallergic functional food ingredient.","PeriodicalId":9175,"journal":{"name":"Bioscience, Biotechnology, and Biochemistry","volume":" ","pages":"795-804"},"PeriodicalIF":1.4,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative analysis of intracellular Nτ-methylhistidine concentration in C2C12 myotubes by liquid chromatography-tandem mass spectrometry. 液相色谱-串联质谱法定量分析C2C12肌管细胞内n τ-甲基组氨酸浓度。

IF 1.4 4区生物学

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-05-21 DOI: 10.1093/bbb/zbaf031

Saki Shimamoto, Miyu Kamimura, Yoshio Nishimura, Jun-Ichi Shiraishi, Shozo Tomonaga, Hanwool Do, Ayumi Katafuchi, Susumu Muroya, Akira Ohtsuka, Daichi Ijiri

{"title":"Quantitative analysis of intracellular Nτ-methylhistidine concentration in C2C12 myotubes by liquid chromatography-tandem mass spectrometry.","authors":"Saki Shimamoto, Miyu Kamimura, Yoshio Nishimura, Jun-Ichi Shiraishi, Shozo Tomonaga, Hanwool Do, Ayumi Katafuchi, Susumu Muroya, Akira Ohtsuka, Daichi Ijiri","doi":"10.1093/bbb/zbaf031","DOIUrl":"10.1093/bbb/zbaf031","url":null,"abstract":"The release of Nτ-methylhistidine from muscle cells into the culture medium is considered an index of muscle protein breakdown. The aim of this study was to establish a quantitative method for measuring the intercellular concentrations of Nτ-methylhistidine and its isomer Nπ-methylhistidine in C2C12 myotubes via liquid chromatography-tandem mass spectrometry with stable isotope dilution analysis. The acceptable linear ranges of detection were both 0.5-250 pmol/mL; r2 = 1.000 (Nτ-methylhistidine), r2 = 0.999 (Nπ-methylhistidine). Culture media and cell extracts from C2C12 myotubes grown in a 6-well plate were considered acceptable samples for detecting the concentration of Nτ-methylhistidine. However, Nπ-methylhistidine was detected in neither the culture medium nor cell extracts. The proposed method can be used to confirm the effects of amino acid depletion on Nτ-methylhistidine levels in C2C12 myotubes. In C2C12 myotubes, culture in an amino acid-depleted medium for 48 h increased intracellular Nτ-methylhistidine levels while decreasing its extracellular level.","PeriodicalId":9175,"journal":{"name":"Bioscience, Biotechnology, and Biochemistry","volume":" ","pages":"849-854"},"PeriodicalIF":1.4,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of 5-epi- and 10-epi-β-selinenes and 5-epi- and 10-epi-costals and their acaricidal activity against Varroa destructor. 5-外皮和10-外皮β-丝氨酸及5-外皮和10-外皮肋片的合成及其对灭螨螨的杀螨活性。

IF 1.4 4区生物学

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-05-21 DOI: 10.1093/bbb/zbaf034

Kento Miura, Kenji Nemoto, Hirosato Takikawa, Yusuke Ogura

引用次数: 0

NtPhyA gene knockout enhances cold stress resistance in Nicotiana tabacum L. 敲除NtPhyA基因增强烟草的冷胁迫抗性。

IF 1.4 4区生物学

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-05-21 DOI: 10.1093/bbb/zbaf028

Duoduo Xu, Kai Pi, Jiajun Luo, Ying Huang, Renxiang Liu

引用次数: 0

Bioaugmentation of microbial fuel cells with Geobacter sulfurreducens strain 60473 for boosting power outputs from food wastes. 用硫还原菌60473对微生物燃料电池进行生物强化，以提高食物垃圾的发电量。

IF 1.4 4区生物学

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-05-21 DOI: 10.1093/bbb/zbaf023

Tomoka Harada, Mizuki Toda, Yohei Yamada, Keisuke Tomita, Atsushi Kouzuma, Kazuya Watanabe

{"title":"Bioaugmentation of microbial fuel cells with Geobacter sulfurreducens strain 60473 for boosting power outputs from food wastes.","authors":"Tomoka Harada, Mizuki Toda, Yohei Yamada, Keisuke Tomita, Atsushi Kouzuma, Kazuya Watanabe","doi":"10.1093/bbb/zbaf023","DOIUrl":"10.1093/bbb/zbaf023","url":null,"abstract":"Microbial fuel cells are expected to be applied to sustainable power generation, while substantial increases in process performances, including power output, are necessary for practical application. Here we examined the utility of bioaugmentation with electro-active bacteria for boosting power outputs from microbial fuel cell reactors. Single-chamber reactors were operated using digester effluent as an inoculum and food wastes as organic substrates, and effects of bioaugmentation with Geobacter sulfurreducens strain 60473 were examined. It has been shown that bioaugmentation with strain 60473 substantially improves organics removal and power output, and the maximum power density (per anode projection area) reaches over 1700 mW m-2, a value tenfold larger than that without bioaugmentation. Metabarcoding analyses showed that Geobacter shared more than 40% of anode bacteria in 60473-augmented reactors. These results suggest the utility of bioaugmentation with strain 60473 for improving the performance of microbial fuel cells treating food wastes.","PeriodicalId":9175,"journal":{"name":"Bioscience, Biotechnology, and Biochemistry","volume":" ","pages":"918-923"},"PeriodicalIF":1.4,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Six-step synthesis and epithelial-mesenchymal transition-inhibitory activity of a tetralone-based vitetrifolin analog. 六步合成及四酮基玻璃体蛋白类似物的上皮-间质过渡抑制活性。

IF 1.4 4区生物学

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-05-21 DOI: 10.1093/bbb/zbaf030

Yusuke Hanaki, Yasunori Sugiyama, Ryo C Yanagita

引用次数: 0

Piceatannol promotes the osteogenic differentiation of human periodontal ligament cells through MAPKs activation. 皮杉醇通过激活MAPKs促进人牙周韧带细胞成骨分化。

IF 1.4 4区生物学

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-05-21 DOI: 10.1093/bbb/zbaf040

Hiromu Morimoto, Hirofumi Inoue, Kotone Date, Shinpei Kawakami, Sadao Mori, Hiroko Maruki-Uchida, Nobuyuki Takahashi, Mariko Uehara

引用次数: 0