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The association between neutrophil to high-density lipoprotein cholesterol ratio and gallstones: a cross-sectional study.
IF 3.5 2区 医学
BMC Public Health Pub Date : 2025-01-14 DOI: 10.1186/s12889-025-21392-5
Yinkang Wang, Xingchen Shang, Yinchao Zhang, Yu Zhang, Wei Shen, Qian Wu, Wenyi Du
{"title":"The association between neutrophil to high-density lipoprotein cholesterol ratio and gallstones: a cross-sectional study.","authors":"Yinkang Wang, Xingchen Shang, Yinchao Zhang, Yu Zhang, Wei Shen, Qian Wu, Wenyi Du","doi":"10.1186/s12889-025-21392-5","DOIUrl":"https://doi.org/10.1186/s12889-025-21392-5","url":null,"abstract":"<p><strong>Objective: </strong>Several studies have discussed the relationship between cholesterol and gallstones, and high-density lipoprotein cholesterol (HDL-C) as a representative of this has been addressed in various diseases. The metric neutrophil to high-density lipoprotein cholesterol ratio (NHR) derived from HDL-C has attracted much attention. The purpose of this article is to examine the relationship between NHR and gallstones in a population of American adults.</p><p><strong>Methods: </strong>This study investigated the correlation between NHR and gallstone prevalence among US adults using population-based data from the 2017-2020 National Health and Nutrition Examination Survey (NHANES). NHR was derived by dividing the neutrophil count by HDL-C. Data were analyzed using a variety of statistical techniques, such as univariate analysis, multivariate analysis, and subgroup analysis. In addition, a receiver operating characteristic curve (ROC) was used to determine the predictive power of the index for the risk of gallstone prevalence.</p><p><strong>Results: </strong>The trial enrolled 6,954 subjects, among whom 746 patients were diagnosed with gallstones. By fully adjusted multivariate logistic regression analysis in the Model 3 section observed a significant positive association between NHR and gallstones with an odds ratio (OR) of 1.05 and a 95% confidence interval (CI) of (1.01, 1.10). The restricted cubic curve (RCS) had a P-Nonlinear = 0.481, suggesting that the relationship was a near-linear one. The area under the curve (AUC) of the ROC curve was 0.550, indicating that NHR has a predictive value for the development of gallstones.</p><p><strong>Conclusion: </strong>This study demonstrated a near-linear correlation between NHR and increased susceptibility to gallstones, and the ROC curve is evidence that NHR has some predictive value for the risk of gallstones, albeit with weak predictive power relative to NPAR (Neutrophil percentage/albumin) and NAR (Neutrophils/albumin). Of course, to confirm these findings, more extensive prospective studies are needed to thoroughly validate the role of NHR in the development of gallstones.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"157"},"PeriodicalIF":3.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What are parents' preferences for Human Papillomavirus vaccination promotion messages and communication? Application of a discrete choice experiment to a French Caribbean setting.
IF 3.5 2区 医学
BMC Public Health Pub Date : 2025-01-14 DOI: 10.1186/s12889-024-21006-6
Frédérique G E Dorleans, Jonathan Sicsic, Valérie Henry, Isabelle Bonmarin, Gwladys Nadia Gbaguidi, Lucie Leon, Jocelyn Raude, Jacques Rosine, Judith E Mueller
{"title":"What are parents' preferences for Human Papillomavirus vaccination promotion messages and communication? Application of a discrete choice experiment to a French Caribbean setting.","authors":"Frédérique G E Dorleans, Jonathan Sicsic, Valérie Henry, Isabelle Bonmarin, Gwladys Nadia Gbaguidi, Lucie Leon, Jocelyn Raude, Jacques Rosine, Judith E Mueller","doi":"10.1186/s12889-024-21006-6","DOIUrl":"10.1186/s12889-024-21006-6","url":null,"abstract":"<p><strong>Introduction: </strong>Human Papillomavirus (HPV) vaccine uptake in the French Caribbean has remained below 25% since introduction in 2007, which is well behind national and international targets. Using a discrete choice experiment (DCE), we explored parental preferences around HPV vaccination and optimized communication content in a sample of parents of middle-school pupils in Guadeloupe.</p><p><strong>Methods: </strong>We conducted a cross-sectional survey in public and private middle age schools in Guadeloupe in June 2023 using an online questionnaire. Across a series of nine hypothetical scenarios, participants were asked to decide to vaccinate or not and how certain they were about this choice. Scenarios differed by five attributes (diseases characteristics, vaccine safety, health professionals or institutions promoting vaccination, social conformity and optimal vaccination age). We used random effect logit and linear regression models to estimate the effects of attribute levels on vaccine acceptance and vaccine eagerness.</p><p><strong>Results: </strong>A total of 389 parents out of the 23,184 pupils' parents completed the DCE survey. The attributes with a significant effect size on theoretical vaccine acceptance were \"social conformity\" and \"optimal vaccination age\". Overall, the odds of scenarios stating high vaccine coverage in adolescents were at least 1.8 (95% CI: 1.2-2.6) times more likely to yield theoretical vaccine acceptance compared to a low vaccine uptake reference. The odds of providing scientific explanation along with age yielded theoretical vaccination acceptance respectively up to 3.2 times higher (95% CI: 1.7 to 6.1) in parents reporting an un vaccinated child and not intention to vaccinate. For vaccine eagerness, we observe significant positive effects of communication content overall when stating high vaccination uptake in adolescents or scientific evidence along with age or mentioning cancer prevention. Parents always refusing vaccination remained unsensitive to communication contents.</p><p><strong>Discussion and conclusion: </strong>These original DCE results highlighted the need for tailoring specific HPV vaccination promotion communication in a French Caribbean setting. Contextual features such as sexuality concerns as regard to age and peers' adhesion to vaccination have to be thoroughly considered. The nationwide HPV vaccination campaign in middle schools should adapt communication in order to raise HPV vaccine uptake in the French Caribbean.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"145"},"PeriodicalIF":3.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142977426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Boys Do Cry: a randomised controlled trial testing the effects of a music video promoting help-seeking for mental health difficulties in Australian men.
IF 3.5 2区 医学
BMC Public Health Pub Date : 2025-01-14 DOI: 10.1186/s12889-024-21172-7
Angela Nicholas, Simone Scotti Requena, Simon Rice, Matthew J Spittal, Andrew MacKinnon, Zac Seidler, Maria Ftanou, Justine Fletcher, Long Le, Cathy Mihalopoulos, Jane Pirkis
{"title":"Boys Do Cry: a randomised controlled trial testing the effects of a music video promoting help-seeking for mental health difficulties in Australian men.","authors":"Angela Nicholas, Simone Scotti Requena, Simon Rice, Matthew J Spittal, Andrew MacKinnon, Zac Seidler, Maria Ftanou, Justine Fletcher, Long Le, Cathy Mihalopoulos, Jane Pirkis","doi":"10.1186/s12889-024-21172-7","DOIUrl":"10.1186/s12889-024-21172-7","url":null,"abstract":"<p><strong>Background: </strong>In Australia and internationally, it is men who predominately die by suicide. Men are less likely than women to seek help for their mental health difficulties and this may contribute to their higher suicide rates. We created a 4-minute music video encouraging Australian men to seek help for mental health difficulties (Boys Do Cry). We aimed to assess in a randomised controlled trial (RCT) whether the Boys Do Cry video increased men's intentions to seek help for mental health difficulties from baseline (T1) to post-intervention (1 week = T2).</p><p><strong>Methods: </strong>We conducted an online single-blind, two-arm RCT comparing the effects of Boys Do Cry against a control video. Analyses were undertaken on an intent-to-treat basis using linear mixed effects models with variables for trial arm, occasion of measurement and their interaction. Intervention effectiveness was assessed by comparing the mean difference between arms in change of the total score on the General Help-Seeking Questionnaire (GHSQ) from T1 to T2.</p><p><strong>Results: </strong>476 participants were randomised (intervention = 243; control = 233). At T1, GHSQ means were similar (intervention = 45.28; control = 45.70). After viewing the videos, GHSQ means increased in both arms (intervention = 47.33; control = 46.59), with no evidence of a difference in scores at T2 (modelled mean difference = 0.62, 95% CI -1.11 to 2.35, p = 0.485). Similar results were observed for all secondary outcomes. No adverse events were observed.</p><p><strong>Conclusions: </strong>Boys Do Cry demonstrated some evidence of a positive effect on help-seeking intentions among Australian men; however, so too did the control video, and no significant difference was observed.</p><p><strong>Trial registration: </strong>ANZCTR No. 2,621,001,008,819. Registered 30 July 2021.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"141"},"PeriodicalIF":3.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142977164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjustment of the Framingham index by abdominal aortic calcification scores enables a more accurate prediction of long-term cardiac events in general population aged 40 years and above: evidence from NHANES 2013-2014.
IF 3.5 2区 医学
BMC Public Health Pub Date : 2025-01-14 DOI: 10.1186/s12889-025-21383-6
Xiao-Jun Liu, Li Wang, Li-Sha Zhang, Li-Fei Cao, Zhao-Fei Wan, Jia-Hong Xue, Yan-Ru He, Xin-Hong Wang, Xiao-Fang Bai
{"title":"Adjustment of the Framingham index by abdominal aortic calcification scores enables a more accurate prediction of long-term cardiac events in general population aged 40 years and above: evidence from NHANES 2013-2014.","authors":"Xiao-Jun Liu, Li Wang, Li-Sha Zhang, Li-Fei Cao, Zhao-Fei Wan, Jia-Hong Xue, Yan-Ru He, Xin-Hong Wang, Xiao-Fang Bai","doi":"10.1186/s12889-025-21383-6","DOIUrl":"https://doi.org/10.1186/s12889-025-21383-6","url":null,"abstract":"<p><strong>Background: </strong>Abdominal aortic calcification (AAC) is considered as a strong predictor of cardiovascular disease (CVD) events. Our study aimed to investigate whether the predicted risk for cardiac death with the Framingham risk score (FRS) could be further improved with the addition of AAC score in general population aged ≥ 40 years.</p><p><strong>Methods: </strong>A total of 2971 participants aged ≥ 40 years in the National Health and Nutrition Examination Surveys (NHANES) 2013-2014 were followed up. The Spearman's rank correlation was performed to explore the correlation between the AAC score and FRS. the Kaplan-Meier method was used to make cumulative cardiac death curve. Predictors of cardiac death was identified by multivariate Cox regression. Additionally, the predictive value of FRS alone and combined with AAC score was estimated by comparing the area under the receiver-operating characteristic (ROC) curve (AUC) and calculating Integrated Discrimination Improvement (IDI).</p><p><strong>Results: </strong>During a median of 70.50 months (interquartile range 58.43-82.57 months), 49 (1.649%) experienced cardiac death in the follow-up. The FRS was positively associated with AAC score. Both FRS and AAC score were independent predictors of cardiac death (hazard ratio 1.216; 95%CI 1.135 to 1.302; p < 0.00001; 1.159; 95%CI 1.109 to 1.211; p < 0.00001; respectively). Furthermore, Kaplan-Meier analysis demonstrated increased risk of cardiac death with increasing AAC score (log-rank 54.548, p<0.0001). The predictive value of FRS significantly was improved by adding with AAC score [increase in AUC from 0.734 to 0.780, p < 0.0001; IDI = 0.007, p = 0.013 ].</p><p><strong>Conclusions: </strong>AAC score is positively related with Framingham index, and FBS adjusted by AAC score further improved the prediction risk for cardiac death in general population aged ≥ 40 years.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"150"},"PeriodicalIF":3.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between Mediterranean diet and metabolic health status among adults was not mediated through serum adropin levels.
IF 3.5 2区 医学
BMC Public Health Pub Date : 2025-01-14 DOI: 10.1186/s12889-025-21299-1
Maryam Shafiei, Donya Poursalehi, Sobhan Mohammadi, Farnaz Shahdadian, Zahra Hajhashemy, Parisa Rouhani, Elahe Mokhtari, Parvane Saneei
{"title":"Association between Mediterranean diet and metabolic health status among adults was not mediated through serum adropin levels.","authors":"Maryam Shafiei, Donya Poursalehi, Sobhan Mohammadi, Farnaz Shahdadian, Zahra Hajhashemy, Parisa Rouhani, Elahe Mokhtari, Parvane Saneei","doi":"10.1186/s12889-025-21299-1","DOIUrl":"https://doi.org/10.1186/s12889-025-21299-1","url":null,"abstract":"<p><strong>Background: </strong>Prevalence of metabolic disorders has been increased in recent years around the world. The relationship between Mediterranean diet (MD) with metabolic health status and serum adropin levels has been less examined in Iranian adults. We investigated the association between MD compliance with metabolic health status and adropin hormone in Iranian adults.</p><p><strong>Methods: </strong>This observational study was conducted on 527 men and women. Food intakes were evaluated by a validated food frequency questionnaire. Blood pressure and anthropometric parameters were measured. Fasting blood samples were drawn to measure serum adropin concentrations, blood glucose, triglycerides, high-density lipoprotein cholesterol, high sensitive C-reactive protein and insulin. Metabolic unhealthy (MU) status was defined as having ≥ 2 cardio-metabolic risk factors.</p><p><strong>Results: </strong>After adjustments for potential confounders, subjects in highest versus lowest tertile of MD had 52% lower odds of MU status (OR = 0.48, 95%CI: 0.23-0.97). Stratified analysis revealed a significant association in normal-weight participants (OR = 0.12; 95%CI: 0.02-0.64), but not in those with overweight/obesity (OR = 0.66, 95%CI: 0.27-1.57). By excluding each component of MD, the association disappeared, except for three components (vegetables, nuts and grains). MD adherence was not significantly related to serum adropin levels in multivariable-adjusted model (unstandardized B= -0.19, 95%CI: -4.97, 4.59; P = 0.94). Serum adropin hormone levels were also not substantially different among metabolic healthy versus unhealthy subjects (P = 0.66).</p><p><strong>Conclusions: </strong>This cross-sectional study showed an inverse association between adherence to MD and odds of MU status, especially in subjects with normal-weight. Serum adropin concentrations were not associated with MD adherence or metabolic health status.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"149"},"PeriodicalIF":3.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined exposure to mixed brominated flame retardants on obstructive sleep apnea syndrome in US adults.
IF 3.5 2区 医学
BMC Public Health Pub Date : 2025-01-14 DOI: 10.1186/s12889-024-21204-2
Junping Liu, Zhaoyue Liu, Xinru Liu, Nan Wang, Lin Wu, Xiaoxue Xu, Wei Liu, Yajie Feng, Huanyu Zhang, Yue Zhou, Xinle Yin, Yaping Liu, Qunhong Wu, Ning Ning, Libo Liang
{"title":"Combined exposure to mixed brominated flame retardants on obstructive sleep apnea syndrome in US adults.","authors":"Junping Liu, Zhaoyue Liu, Xinru Liu, Nan Wang, Lin Wu, Xiaoxue Xu, Wei Liu, Yajie Feng, Huanyu Zhang, Yue Zhou, Xinle Yin, Yaping Liu, Qunhong Wu, Ning Ning, Libo Liang","doi":"10.1186/s12889-024-21204-2","DOIUrl":"10.1186/s12889-024-21204-2","url":null,"abstract":"<p><strong>Background: </strong>Accumulating research highlights that exposure to serum brominated flame retardants (BFRs) may elevate health risks. The effects of serum BFRs, both alone and in combination, on obstructive sleep apnea syndrome (OSAS) have not been thoroughly studied. Our main goal was to examine the association between individual and mixtures of serum BFRs and OSAS risk.</p><p><strong>Methods: </strong>Data from the National Health and Nutrition Examination Survey (NHANES) were employed, including 1,341 participants. We included participants with full details on OSAS, covariates, and 7 types of serum BFRs (PBDE28, PBDE47, PBDE99, PBDE100, PBDE153, PBB153, and PBDE209). To investigate the OSAS risk with BFRs exposure, multivariate logistic regression, weighted quantile sum (WQS) regression, quantile g-computation (QGC), Bayesian kernel machine regression (BKMR) models, and restricted cubic splines (RCS) were implemented.</p><p><strong>Results: </strong>Serum BFRs, including PBDE28, PBDE47, PBDE99, PBDE100, and PBB153, showed positive correlations with the OSAS risk. The toxic effect of serum BFRs co-exposure on OSAS risk was consistently demonstrated through the results of WQS regression, QGC and BKMR models. PBB153 was determined to be the most weighted BFRs. Additionally, RCS regression model also verified the strong non-linear relationship that existed between OSAS risk and PBB153.</p><p><strong>Conclusions: </strong>Findings of the study prove that BFRs co-exposure exerts a deleterious effect on OSAS risk. Future large-scale prospective investigations and experimental studies are desirable to confirm these findings.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"146"},"PeriodicalIF":3.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142977197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between traffic-related air pollution and risk of outpatient visits for dry eye disease in a megacity along the subtropical coast in South China.
IF 3.5 2区 医学
BMC Public Health Pub Date : 2025-01-14 DOI: 10.1186/s12889-025-21319-0
Fan Cao, Yue Chen, Yan-Chao Gui, Zi-Yue Fu, Zheng Lyu, Kou Liu, Li-Ming Tao, Zhi-Fan Chen, Hai-Feng Pan, Zheng-Xuan Jiang, Qian-Li Meng
{"title":"Association between traffic-related air pollution and risk of outpatient visits for dry eye disease in a megacity along the subtropical coast in South China.","authors":"Fan Cao, Yue Chen, Yan-Chao Gui, Zi-Yue Fu, Zheng Lyu, Kou Liu, Li-Ming Tao, Zhi-Fan Chen, Hai-Feng Pan, Zheng-Xuan Jiang, Qian-Li Meng","doi":"10.1186/s12889-025-21319-0","DOIUrl":"https://doi.org/10.1186/s12889-025-21319-0","url":null,"abstract":"<p><strong>Background: </strong>Traffic-related air pollution especially in highly socioeconomically developed megacity is usually considered as a severe problem leading to inevitable adverse health outcomes. This study aimed to investigate the associations between traffic-related air pollutants with risk of dry eye disease (DED) outpatient visits in a megacity (Guangzhou) along the subtropical coast in South China.</p><p><strong>Methods: </strong>Daily data on DED outpatient visits and environmental variables from 1 January 2014 to 31 December 2020 in Guangzhou were obtained. A time-series study using a quasi-Poisson generalized linear model (GLM) combined with distributed lag non-linear model (DLNM) was adopted. Subgroup analyses stratified by age, gender, and season were conducted.</p><p><strong>Results: </strong>Totally, 27, 828 DED cases were identified during the study period including 2557 days. Daily number of outpatient visits for DED ranged from 0 to 41. An increase of 10 μg/m<sup>3</sup> in PM<sub>2.5</sub>, NO<sub>2</sub> and SO<sub>2</sub> concentration was associated with 3.1%, 5.9% and 17.4% increase in the risk of DED outpatient visits, respectively (RR<sub>PM2.5</sub> = 1.031, 95%CI: 1.004-1.059, lag 0-11 day; RR<sub>NO2</sub> = 1.059, 95% CI: 1.027-1.092, lag0-14 day; RR<sub>SO2</sub> = 1.174, 95% CI: 1.036-1.330, lag0-13 day). Subgroup analyses indicated that the effects of PM<sub>2.5</sub> exposure on the risk of DED outpatient visits remained significant in aged < 60 years (RR <sub>max</sub> = 1.008, 95% CI: 1.003-1.013, lag0 day) and the effects of SO<sub>2</sub> exposure on the DED outpatient visits risk remained significant in the females (RR <sub>max</sub> = 1.025, 95% CI: 1.006-1.044, lag0 day). The associations of PM<sub>2.5</sub> (RR = 1.010, 95% CI: 1.003-1.016, lag0 day) and SO<sub>2</sub> (RR = 1.030, 95% CI: 1.003-1.058, lag14 day) exposure with DED outpatient visits risk remained significant in warm seasons, whereas NO<sub>2</sub> (RR = 1.006, 95% CI: 1.002-1.009, lag14 day) exposure was significantly associated with DED outpatient visits in cold seasons. The associations of PM<sub>2.5</sub> (first visit, RR = 1.006, 95% CI: 1.001-1.011, lag0 day; re-visit, RR = 1.002, 95% CI: 1.000-1.005, lag6 day), NO<sub>2</sub> (first visit, RR = 1.006, 95% CI: 1.001-1.012, lag0 day; re-visit, RR = 1.007, 95% CI: 1.002-1.012, lag0 day), and SO<sub>2</sub> (first visit, RR = 1.023, 95% CI: 1.002-1.044, lag0 day; re-visit, RR = 1.023, 95% CI: 1.000-1.045, lag0 day) exposure with risk of DED outpatient visits were significant for both first- and re-visits.</p><p><strong>Conclusions: </strong>Our study revealed that short-term exposure to PM<sub>2.5</sub>, NO<sub>2</sub> and SO<sub>2</sub> were positively associated with risk of DED outpatient visits, especially for the youngers, females and during warm seasons, providing evidence for making public health policy to improve life quality in developed megacity.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"151"},"PeriodicalIF":3.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of continuation on HIV pre-exposure propylaxis among female sex workers at a referral hospital in Uganda: a mixed methods study using COM-B model.
IF 3.5 2区 医学
BMC Public Health Pub Date : 2025-01-14 DOI: 10.1186/s12889-024-20975-y
Samuel Kawuma, Rodgers Katwesigye, Happy Walusaga, Praise Akatukunda, Joan Nangendo, Charles Kabugo, Moses R Kamya, Fred C Semitala
{"title":"Determinants of continuation on HIV pre-exposure propylaxis among female sex workers at a referral hospital in Uganda: a mixed methods study using COM-B model.","authors":"Samuel Kawuma, Rodgers Katwesigye, Happy Walusaga, Praise Akatukunda, Joan Nangendo, Charles Kabugo, Moses R Kamya, Fred C Semitala","doi":"10.1186/s12889-024-20975-y","DOIUrl":"10.1186/s12889-024-20975-y","url":null,"abstract":"<p><strong>Background: </strong>Female sex workers (FSWs) have the highest HIV prevalence in Uganda. Pre-exposure prophylaxis (PrEP) has been recommended as a key component of the HIV combination prevention strategy. Although patient initiation of PrEP has improved, continuation rates remain low. This study evaluated PrEP continuation among FSWs and explored potential determinants of PrEP adherence within a public referral hospital in urban Uganda.</p><p><strong>Methods: </strong>We conducted an explanatory sequential mixed method study at Kiruddu National referral hospital in Uganda. Secondary data on socio demographic characteristics and follow up outcomes of at least one year was collected for all FSWs who were initiated PrEP between May 2020 and April 2021 and data analyzed on July 15,2023. We used Kaplan-Meier survival analysis to evaluate continuation on PrEP from time of initiation and follow-up period. The capability, opportunity, and motivation to change behaviour model was used to explore perspectives and practices of FSWs (n = 24) and health care providers (n = 8) on continuation on PrEP among FSWs, using semi structured interviews. The qualitative data was deductively coded and analyzed thematically, categorizing the themes related to PrEP continuation as facilitators and barriers.</p><p><strong>Results: </strong>Of the 292 FSWs initiated on PrEP, median age was 26 years (interquartile range, 21-29), 101 (34.6) % were active on PrEP, 137 (46.9%) were lost to follow-up, 45 (15.4%) were no longer eligible to continue PrEP, eight (2.7%) were transferred out and one (0.3%) had died. Median survival time on PrEP was 15 months (Interquartile range IQR, 3-21). The continuation rates on PrEP at six (6) and 12 months were 61.1% and 53.1%, respectively. Facilitators of PrEP continuation included awareness of risk associated with sex work, integration of PrEP with other HIV prevention services, presence of PrEP Peer support and use of Drop-in centers. The barriers included low community awareness about PrEP, high mobility of sex workers, substance abuse, and the unfavorable daytime clinic schedules. However, the quantitative findings from the multivariable Cox Proportional Hazards Model did not align with the reported findings for the qualitative evaluation.</p><p><strong>Conclusion: </strong>Continuation on PrEP remains low among FSWs. Interventions for PrEP continuation should address barriers such as low community awareness of PrEP, substance abuse and restrictive health facility policies for scale of the PrEP program among FSWs in Uganda. Integration of PrEP with other services and scale up of community PrEP delivery structures may improve its continuation.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"143"},"PeriodicalIF":3.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142977429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the relationship between nutrition literacy, Mediterranean diet compliance, ecological footprint and sustainable environmental attitudes in adolescents.
IF 3.5 2区 医学
BMC Public Health Pub Date : 2025-01-13 DOI: 10.1186/s12889-024-20910-1
Özge Mengi Çelik, Emine Merve Ekici, Selin Yılmaz, Ziya Erokay Metin
{"title":"Evaluation of the relationship between nutrition literacy, Mediterranean diet compliance, ecological footprint and sustainable environmental attitudes in adolescents.","authors":"Özge Mengi Çelik, Emine Merve Ekici, Selin Yılmaz, Ziya Erokay Metin","doi":"10.1186/s12889-024-20910-1","DOIUrl":"10.1186/s12889-024-20910-1","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the relationship between nutrition literacy, Mediterranean diet compliance, ecological footprint and sustainable environmental attitudes in adolescents.</p><p><strong>Methods: </strong>This descriptive and cross-sectional study was conducted with 673 adolescents aged 14-18 years. The individuals' general characteristics were questioned. Sustainable environmental attitudes, nutritional literacy status and compliance with the Mediterranean diet were assessed with the help of scales. An ecological footprint calculator was used for the calculation of the ecological footprint.</p><p><strong>Results: </strong>The mean age of the individuals was 16.5 ± 1.42 years. Adolescent Nutrition Literacy Scale score and Sustainable Environmental Attitude Scale score were higher in female adolescents than in males (p < 0.05). Ecological Footprint score was higher in male adolescents than in females (p < 0.05). A statistically significant positive correlation was found between Adolescent Nutrition Literacy Scale score, Sustainable Environmental Attitude Scale score and Mediterranean Diet Quality Index (KIDMED) score (p < 0.05). It was determined that sex and Sustainable Environmental Attitude Scale score affected the Ecological Footprint total score (p < 0.05). It was determined that sex, Adolescent Nutrition Literacy Scale score and Ecological Footprint total score affected the Sustainable Environmental Attitude Scale score (p < 0.05). Also, it was determined that Adolescent Nutrition Literacy Scale score affected the KIDMED score (p < 0.05).</p><p><strong>Conclusions: </strong>Girls have higher nutritional literacy and sustainable environmental attitude. Nutrition literacy, sustainable environmental attitude and KIDMED total scores showed a significant positive correlation with each other. Nutritional literacy is effective on sustainable environmental attitude and compliance with the Mediterranean diet. Sustainable environmental attitude is effective in reducing the ecological footprint.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"130"},"PeriodicalIF":3.5,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11727382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delays in health care seeking for diarrheal disease and associated factors among caregivers of under five children in health centers of northwest Ethiopia: a mixed-method study.
IF 3.5 2区 医学
BMC Public Health Pub Date : 2025-01-13 DOI: 10.1186/s12889-025-21300-x
Asnakech Marew, Zenebe Jebero Zaza, Shiferaw Birhanu, Amare Belachew, Tsehaynew Kasse
{"title":"Delays in health care seeking for diarrheal disease and associated factors among caregivers of under five children in health centers of northwest Ethiopia: a mixed-method study.","authors":"Asnakech Marew, Zenebe Jebero Zaza, Shiferaw Birhanu, Amare Belachew, Tsehaynew Kasse","doi":"10.1186/s12889-025-21300-x","DOIUrl":"10.1186/s12889-025-21300-x","url":null,"abstract":"<p><strong>Background: </strong>Approximately 70% of child deaths due to diarrhea are caused by a lack of timely healthcare. However, there was little evidence of factors associated with delays in seeking health care for patients with diarrheal diseases in the study area. Therefore, this study aimed to investigate delays in seeking healthcare for children with diarrhea and identify associated factors among caregivers in health centers of Northwest Ethiopia.</p><p><strong>Method and materials: </strong>An institution-based mixed study method was conducted from May to June 2022. Quantitative data were collected from 374 participants who were selected by systematic random sampling using a structured interviewer-administered questionnaire and chart review. The data were analyzed using the Statistical Package for Social Science software version 25. Bivariable and multivariable logistic regression models were used to identify associated factors. Variables with a p- value < 0.05 in the multivariable analysis were considered to be significantly associated. Qualitative data were collected from participants in waiting area after receiving treatments via in-depth interviews and analyzed using open-source software. The qualitative data were transcribed, translated, coded, thematized, and interpreted accordingly.</p><p><strong>Results: </strong>In this study, 53.48% of patients experienced delays in seeking healthcare for diarrhea. A large family size (adjusted odds ratio (AOR) = 2.64, 95% CI: 1.26-5.4), poor knowledge about diarrhea danger signs (AOR = 3.25, 95% CI: 1.6-6.6), difficulty paying for treatment (AOR = 2.95, 95% CI: 1.6-5.3), not visiting health facilities as the first response to diarrhea (AOR = 3.94, 95% CI: 1.96-7.9), only diarrhea (AOR = 2.39, 95% CI: 1.01-5.63), and no information about early healthcare seeking (AOR = 4.88, 95% CI: 1.91-12.43) were identified; moreover, from the qualitative findings, mothers' perceptions of the illness were mild, poor service provision, and economic problems were determinants of delay. Awareness, barriers, compliance, and perception emerged as themes.</p><p><strong>Conclusion: </strong>The prevalence of delays in seeking healthcare for children with diarrhea was high. This poses a negative health risk to the lives of children and their caregivers. A large family size, poor knowledge about diarrhea danger signs, difficulty paying for treatment, and many others were factors associated with delayed health care seeking. Hence, the government and other concerned stakeholders should give due emphasis to tackling the identified causes of delay in seeking health care for children under five years of age with diarrhea by diverting community focus toward timely care seeking and disease prevention.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"138"},"PeriodicalIF":3.5,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142977417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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