BMC Public Health最新文献

{"title":"The impact of the COVID-19 pandemic on healthy volunteer motivations: a mixed-methods study of participants in plague vaccine trials in the UK and Uganda.","authors":"Arabella Sv Stuart, Richard Muhumuza, Sylvia Kusemererwa, Maria Teddy Ndagire, Matilda Hill, Peter J O'Reilly, Martin Onyango, Wasswa Solomon, Penelope Akankunda, Sylvia Masawi, Shamim Ssendagire, Denis Murphy, Samantha Vanderslott, Christine S Rollier, Eugene Ruzagira, Andrew J Pollard, Nambusi Kyegombe","doi":"10.1186/s12889-026-27297-1","DOIUrl":"https://doi.org/10.1186/s12889-026-27297-1","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic led to unprecedented interest and participation in vaccine trials globally, and a concurrent increase in vaccine hesitancy. Whether this impacted recruitment of healthy volunteers to subsequent non-COVID vaccine trials is not well studied. We explored the impact of the COVID-19 pandemic on motivations for participating in two clinical trials of the same novel anti-plague vaccine, conducted in the United Kingdom (UK) and Uganda in 2021 and 2022.</p><p><strong>Methods: </strong>Participants enrolled in PlaVac (UK) and PlaVac Uganda, Phase I trials of ChAdOx1 Plague vaccine, were invited to complete an optional questionnaire and semi-structured interview examining motivations for participating, including questions on the impact of the COVID-19 pandemic on their decision. Questionnaires were self-administered and interviewer-administered for UK and Uganda studies, respectively. Interviews were conducted in local languages, transcribed in English, and analysed using thematic analysis. Results were compared between studies.</p><p><strong>Results: </strong>Thirty-one of the 45 (68.9%; 25.8% female) UK trial participants and all 36 (100.0%; 27.8% female) of the Uganda trial participants completed questionnaires responses, and 19 Uganda questionnaire respondents completed interviews. Responses to questions on the impact of the COVID-19 pandemic on volunteering decisions were divergent between countries, with little effect for UK participants but a strong positive effect for Ugandan participants. Themes relating to this effect were \"contributor, not cause\" in the UK, and in Uganda were preparedness (wanting to contribute to vaccine development to prevent suffering and death from future epidemics), increased awareness (understanding the vaccine development process and seeing rapidly deployed COVID-19 vaccine trials gave them confidence), and personal protection (believing themselves to be protected by the novel plague vaccine). Participants in both studies expressed trust and confidence in the study vaccine which shares the same adenoviral-vectored platform technology used to elicit an immune response (ChAdOx1) with the COVID-19 vaccine ChAdOx1 nCoV-19 (Vaxzevria, AstraZeneca).</p><p><strong>Conclusions: </strong>For Ugandan participants, COVID-19 and mass vaccination increased knowledge about vaccines and trials and encouraged them to participate in research, but had little impact on UK volunteers. There was no evidence of a negative effect of perceptions of the related ChAdOx1 nCoV-19 vaccine on trial participants' confidence in the novel plague vaccine's safety.</p><p><strong>Trial registrations: </strong>Current controlled trial: ISRCTN41077863, prospective registration date: 19/03/2021, and current controlled trial: ISRCTN79243381, prospective registration date 05/08/2022.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of humidex on other infectious diarrhea: a study of seasonal heterogeneity and lagged effects using a distributed lag non-linear model.","authors":"Ruoyu Gui, Wei Zhou, Jinsong Deng, Leiyu Shi, Guangli Hu, Gang Sun, Yingrong Lao","doi":"10.1186/s12889-026-27645-1","DOIUrl":"https://doi.org/10.1186/s12889-026-27645-1","url":null,"abstract":"<p><strong>Objective: </strong>Global climate changehas led to frequent extreme hot and humid events. The Humidex, as a comprehensive temperature and humidity indicator, is closely related to infectious diseases. Other infectious diarrhea is an important public health issue, but the expode-response relationship between it and Humidex, especially the seasonal effect modification and lag effect patterns, still lacks systematic research. This study aims to evaluate the impact of Humidex on the incidence of other infectious diarrhea and explore its seasonal heterogeneity and time lag effect.</p><p><strong>Methods: </strong>Using daily OID case and meteorological data from Guangdong Province (2014-2023), a Distributed Lag Non-linear Model was applied to assess the cumulative effects of Humidex, adjusting for season, day of the week, and holidays. Analyses included establishing the overall exposure-response relationship, stratifying by warm (May-October) and cold (November-April) seasons to examine effect modification, and conducting sensitivity analyses to verify robustness.</p><p><strong>Results: </strong>At the extreme Humidex exposure level (P95, 42.27), the cumulative relative risk (CRR) for OID was 1.183 (95% CI: 1.057-1.323), indicating a significant 18.3% increase in risk, with an attributable fraction (AF) of 15.4%. Conversely, a protective effect was observed at the low Humidex level (P5, 11.3) (RR = 0.832, 95% CI: 0.748-0.926). Lag analysis at high Humidex levels (e.g., P75, P90) showed that the highest risk occurred within 0-2 days after exposure, indicating a short-term lag effect. Seasonal stratification revealed significant effect modification: during the cold season, extreme Humidex showed a protective effect (RR = 0.523, 95% CI: 0.319-0.856), while the effect was non-significant in the warm season (RR = 0.957, 95% CI: 0.880-1.040), with a seasonal effect ratio of 1.83. Sensitivity analyses confirmed the robustness of the findings to variations in lag periods and degrees of freedom for splines.</p><p><strong>Conclusion: </strong>Humidex is significantly associated with OID incidence, showing a non-linear exposure-response relationship and clear seasonal effect modification. While extreme Humidex generally increases OID risk, anomalously high levels during the cold season exhibit a protective effect. These findings support the development of season-specific early warnings and targeted public health interventions based on the Humidex index.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myalgic Encephalomyelitis/Chronic Fatigue Syndrome diagnostic reporting in the 2021-2023 National Health Interview Survey.","authors":"Katherine Fleig, Richard Nahin, Barbara Stussman, Miciah Wilkerson, Elizabeth R Unger, Jin-Mann S Lin, Brian Walitt","doi":"10.1186/s12889-026-27598-5","DOIUrl":"https://doi.org/10.1186/s12889-026-27598-5","url":null,"abstract":"<p><strong>Background: </strong>Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic disabling illness characterized by activity limitations associated with fatigue, post-exertional malaise (PEM), unrefreshing sleep, memory and concentration problems, orthostatic intolerance and painful discomfort. While typically considered to be a chronic condition, some persons who have had ME/CFS report no longer having the disorder. Here, the prevalence and characteristics of adults in the United States who self-report having an ME/CFS diagnosis and those who self-report no longer having ME/CFS are presented.</p><p><strong>Methods: </strong>The current study utilized publicly available data from the 2021-2023 National Health Interview Survey, which interviewed 86,655 United States civilian non-institutionalized adults about their health. For this study, participants were categorized into three groups: Current ME/CFS (individuals currently diagnosed with ME/CFS), Past ME/CFS (individuals who were previously diagnosed but no longer report having the condition), and Never ME/CFS (individuals who have never been diagnosed with ME/CFS). These groups were characterized using descriptive statistics.</p><p><strong>Results: </strong>In the United States adult population, 20.7% of the estimated 1.5% adults who ever received an ME/CFS diagnosis report they no longer have the condition (Past ME/CFS). Overall the Past ME/CFS group reported experiencing symptoms less frequently, less difficulty with daily living, approximately equal prevalence of comorbidities, and better general health status than the Current ME/CFS group but remained significantly impaired compared to the Never ME/CFS group. However, 40-50% of adults with Past ME/CFS report symptoms and function similar to adults with Current ME/CFS and only approximately 25% had substantially less symptoms and better function compared to those with Current ME/CFS. Comorbidities did not differ significantly between the Current and Past ME/CFS groups.</p><p><strong>Conclusion: </strong>Further study to better understand the reasons why those in the Past ME/CFS group report no longer having the disorder is important for understanding the natural history and disease burden of ME/CFS. Studying symptomatic remissions, and the underlying physiology of improvement, could lead to identification of new disease modifying therapeutic approaches.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the dynamics between homelessness and healthcare access for Aboriginal and Torres Strait Islander women with traumatic brain injury from family violence: a qualitative study.","authors":"Michelle Fitts, Karen Soldatic","doi":"10.1186/s12889-026-26458-6","DOIUrl":"https://doi.org/10.1186/s12889-026-26458-6","url":null,"abstract":"<p><strong>Background: </strong>Homelessness is a significant issue in the context of violence, particularly for Indigenous women in settler colonial countries, as are the long-lasting impacts of violence such as traumatic brain injury (TBI) including concussion. Understanding of the relationship between homelessness and healthcare access for TBI from violence among Indigenous women is critical for informing service delivery; however, research in this area remains limited. Situated within the broader experiences of accessing healthcare following violence-related TBI, this study aimed to explore the relational dynamics between violence, homelessness, healthcare access, and the implications for long term recovery and wellbeing.</p><p><strong>Methods: </strong>Using purposive and snowball sampling, semi-structured interviews and focus groups were completed with 18 Indigenous women who have experienced TBI from violence, 28 community members, and 90 community-based frontline workers to gather insights into the experiences of living with TBI family violence or supporting someone with this injury. All data were transcribed verbatim and analyzed using thematic analysis.</p><p><strong>Results: </strong>Two themes were identified regarding how responses to family violence-related homelessness created barriers for Indigenous women to access healthcare for TBI: (1) Housing service barriers affect access to healthcare and TBI management, and (2) The (in)visibility of TBI within crisis accommodation and housing services. The dominant experience for Indigenous women who had experienced violence and homelessness was characterized by complexity, uncertainty, and distress, largely due to service delays and barriers encountered across housing pathways. Some Indigenous women were required to relocate away from their home region to secure temporary accommodation. While crisis accommodation services were widely viewed as places of safety, many did not consider TBI in environmental design or service delivery. Multi-agency case management and outreach were identified as valuable approaches for improving healthcare access.</p><p><strong>Conclusions: </strong>The findings illustrate the importance of TBI-informed policy and practice within housing and homelessness services, especially for Indigenous women in rural and remote regions, alongside strengthened workforce training. Stronger linkages between women's shelters, housing services, and healthcare systems - including concussion clinics - are critical for supporting both immediate and long-term care. Needs-based funding is required to ensure regional and remote housing systems can support women-led responses, including more streamlined transitions from crisis or short-term accommodation to secure housing.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masticatory function and frailty: insights from NHANES and CHARLS.","authors":"Ronghui Xiang, Jiaqi Wu, Yunan Zhang, Gongwei Wen, Haiyan Zhao, Xuan Zhang, Ziyang Zheng","doi":"10.1186/s12889-026-27510-1","DOIUrl":"https://doi.org/10.1186/s12889-026-27510-1","url":null,"abstract":"<p><strong>Background: </strong>The association between oral health and frailty has been established. This study aimed to examine the association between masticatory function (assessed by functional tooth units (FTU) and edentulism), and frailty status with mortality risk among frail individuals.</p><p><strong>Methods: </strong>Data from National Health and Nutrition Examination Survey (NHANES) and China Health and Retirement Longitudinal Study (CHARLS) were analyzed. Masticatory function was assessed using FTU and edentulism. Frailty was defined using a 49-item and 32-item index in NHANES and CHARLS respectively. Multivariate logistic regression and Cox proportional hazards models, and restricted cubic spline analyses were used to examine associations between mastication, frailty, and mortality. Sensitivity analyses were conducted.</p><p><strong>Results: </strong>The prevalence of frailty was 29.97% and 10.66% in NHANES and CHARLS respectively. Individuals having FTU of 10-12 showed a 24% lower risk of frailty compared to those with FTU of 0-3 in NHANES, and edentulism had 88% higher risk in CHARLS. Among frail participants, higher FTU scores were linked to lower all-cause (HR = 0.73, 95% CI: 0.60-0.89) and cancer-related mortality (HR = 0.51, 95% CI: 0.33-0.80), but not cardiovascular mortality in NHANES, and edentulism had 56% higher mortality in CHARLS. The association between FTU and frailty was linear, subgroups and sensitivity analyses confirmed robustness.</p><p><strong>Conclusions: </strong>Better masticatory function, as indicated by higher FTU, is associated with lower frailty prevalence and improved survival among frail individuals, while edentulism linked to higher prevalence and mortality. These findings emphasize the importance of maintaining functional dentition and oral rehabilitation in geriatric care.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Policy challenges in the provision of COVID-19 border screening: evidence from eight countries.","authors":"James Bates, Joshua R Moon, Sibylle Gaisser, Anne Nikiforov, James G Ryan, Choon Key Chekar, Robyn Meurant, Etienne Vignola-Gagné, Collins Iwuji, Erofili Grapsa, David Barbéra-Tomás, Enrique Meseguer, Gail Davey, Michael M Hopkins","doi":"10.1186/s12889-026-27355-8","DOIUrl":"https://doi.org/10.1186/s12889-026-27355-8","url":null,"abstract":"<p><strong>Background: </strong>While border screening measures were widely adopted by countries during the COVID-19 pandemic, a lack of consensus on the utility of border screening created a gap in best practice for its implementation. As such, countries adopted a diversity of approaches, providing an opportunity to evaluate the configuration and evolution of border screening systems. The article addresses three questions: (i) how did countries configure their border screening systems for COVID-19? (ii) In what contexts did countries rely on public or private providers of these services? (iii) what do policies and narratives reveal about the perceived role of border screening in global public health? The article contributes to long-standing debates over the private sector's role in public health and the perceived value of border screening measures.</p><p><strong>Methods: </strong>This article presents results from an international comparative study based on tracking the organisation of border screening in eight countries. Secondary data was collected between July 2021 - June 2022 from official government websites and policy publications, private sector sources where relevant, and trusted media sources in each study country. The countries included are Australia, Canada, Germany, Ireland, South Africa, South Korea, Spain, and the United Kingdom.</p><p><strong>Results: </strong>All study countries used private provision for pre-departure diagnostic testing for international travellers. In contrast, screening of arriving travellers was more diverse. Countries that opted for private sector post-arrival screening saw governance challenges around accreditation and monitoring of providers, while public service provision saw challenges in capacity and high resource costs. Travel was often framed as a 'luxury,' allowing states to shift responsibility for obtaining tests onto individuals; especially in the context of individuals travelling from low income to high income countries.</p><p><strong>Conclusions: </strong>The different approaches countries followed for screening of departing and incoming travellers suggests wealthy countries were more oriented towards defending their populations against disease importation, rather protecting the international community from disease exportation. These findings provide an opportunity to reflect on the purpose and implementation of border screening. We emphasise a need for further discussion on the efficacy of border screening from both perspectives, given the tendency for countries to rely on these measures.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimated burden of acute gastroenteritis and foodborne gastroenteritis caused by non-typhoidal Salmonella enterica, Shigella and norovirus in Gansu Province, Northwest China.","authors":"Xiang-Lai Sang, Yu-Fang Fan, Xiao-Cheng Liang, Jian-Dong Li, Yan Chen","doi":"10.1186/s12889-026-27563-2","DOIUrl":"https://doi.org/10.1186/s12889-026-27563-2","url":null,"abstract":"<p><strong>Background: </strong>Information on the burden of disease caused by foodborne pathogens in Northwest China is limited. This study aims to estimate the burden of acute gastroenteritis (AGE) and foodborne salmonellosis, shigellosis and norovirus gastroenteritis in Gansu Province.</p><p><strong>Methods: </strong>Using data from population surveys conducted during 2011-2015, the burden of AGE was estimated in Gansu Province. By determining the number of pathogen-specific cases from sentinel hospital surveillance conducted during 2014-2019, with adjustments applied for healthcare-seeking behavior and stool specimen submission based on data from population surveys, the burden of foodborne gastroenteritis caused by non-typhoidal Salmonella enterica, Shigella and norovirus in Gansu Province was calculated. A multiplier calculation model was developed, using Monte Carlo simulation to perform uncertainty estimation.</p><p><strong>Results: </strong>The adjusted monthly prevalence of AGE was 4.0%, equivalent to an average of 0.53 episodes of AGE per person-year in the region. The multiplier for salmonellosis was estimated at 1,739, for shigellosis at 1,646, and for norovirus gastroenteritis at 2,787. The estimated annual incidence of foodborne salmonellosis, shigellosis and norovirus gastroenteritis were 242, 36, and 567 cases per 100,000 population, respectively, which substantially exceeded the incidence of reported foodborne disease.</p><p><strong>Conclusions: </strong>We concluded that AGE and foodborne gastroenteritis caused by non-typhoidal S. enterica, Shigella and norovirus constitute a significant health burden in Gansu Province. By continuously implementing population survey and enhanced sentinel hospital surveillance, with constructing a multiplier calculation model to estimate the burden of disease, we may gain a better understanding of the food safety situation in Northwest China.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of trimester-specific nutrition counseling on maternal vitamin D status, and perinatal outcomes in India: a quasi-experimental cohort study.","authors":"Mohd Faisal Khan, Mohammed Al-Zharani, Ashok Khurana, K Aparna Sharma, Aruna Nigam, Sana Alam, Fahd A Nasr, Wajhul Qamar, Md Ghaznavi Idris, Shakilur Rahman, Kapil Dev","doi":"10.1186/s12889-026-27315-2","DOIUrl":"https://doi.org/10.1186/s12889-026-27315-2","url":null,"abstract":"<p><strong>Background: </strong>Vitamin D deficiency affects more than 90% of Indian pregnant women, yet its isolated impact on perinatal outcomes remains unclear amid multifactorial nutritional challenges. These pose a challenge to achieving SDG 3.2 targets for reducing neonatal mortality. This study evaluated the effects of trimester-specific nutritional counseling on maternal vitamin D status, nutritional practices, and perinatal outcomes in an Indian cohort.​ METHODS: A quasi-experimental prospective cohort study was conducted among 173 (88 intervention, 85 control) pregnant women (8-14 weeks of gestation) at a tertiary hospital in New Delhi between October 2023 and May 2025. The intervention included individualized counseling on vitamin D-rich foods, protein, lipids, and weight management at 8-14, 24-28, and 32-36 weeks, along with supplementation. Controls received standard care. Outcomes included serum 25(OH)D, nutrient intake, gestational weight gain, birth weight, and mode of delivery. Analyses used t-tests, correlations, and multivariate regression (p < 0.05, FDR-adjusted).​ RESULTS: A total of 173 participants completed the study. Baseline severe vitamin D deficiency improved significantly more in the intervention group than in the control group, with a large effect size (Cohen's d = 0.97). Protein intake increased, and nutrition knowledge scores improved substantially following the intervention (p < 0.05). Birth weights were comparable between groups, and no significant association was observed between maternal vitamin D levels and birth weight. Instead, gestational weight gain, protein intake, and caloric intake emerged as significant predictors of low birth weight (OR 0.73-0.995), while vitamin D was not a significant factor. Higher maternal BMI was associated with an increased likelihood of cesarean delivery (OR 0.87, p < 0.05).</p><p><strong>Conclusion: </strong>Trimester-specific nutritional counseling improved maternal vitamin D status and dietary practices but was not significantly associated with birthweight. Overall nutritional adequacy, particularly protein intake and gestational weight gain, appeared more closely related to fetal growth. These findings should be interpreted in light of the study design and warrant confirmation in larger studies.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The quality of video information related to smoking cessation on mainstream short-video platforms in China: a cross-sectional study.","authors":"Xingwang Qiu, Yuancen Shi, Xia Luo, Shixuan Yuan, Jin Zhang, Hua Guan","doi":"10.1186/s12889-026-27667-9","DOIUrl":"https://doi.org/10.1186/s12889-026-27667-9","url":null,"abstract":"<p><strong>Background: </strong>Tobacco use remains one of the greatest public health challenges worldwide. Social short-video platforms have become the primary channel through which the public obtains smoking-cessation information. Grounded in the Health Belief Model and the Theory of Planned Behavior, this study evaluates the information quality of smoking-cessation short videos on Chinese short-video platforms.</p><p><strong>Methods: </strong>We analyzed 262 video samples from four major platforms-TikTok, Kwai, Bilibili, and BuzzVideo. Two researchers who received standardized training independently evaluated each video using the Medical Quality Video Evaluation Tool (MQ-VET), the Global Quality Scale (GQS), and the mDISCERN score. Finally, we performed multiple linear regression to identify factors influencing video quality and user interaction.</p><p><strong>Results: </strong>Of the 262 videos included, only 17.6% were produced by medical experts. Overall information quality was low: median MQ-VET was 44 (41-47), median GQS was 2 (2-3), and median mDISCERN was 2 (1-2). In multivariable regression, videos produced by Medical experts (β = 0.586, p < 0.001) and by Public welfare organizations (β = 0.130, p = 0.001) had significantly higher quality than those produced by Individual users. For user engagement, measured by number of likes, information quality (MQ-VET) (β = 0.215, p = 0.009), TikTok as the platform (β = 0.358, p < 0.001), and Bilibili as the platform (β = 0.485, p < 0.001) were significant positive predictors. Quality scores correlated positively with user interaction (ρ = 0.14-0.35, p < 0.005), whereas video duration correlated negatively with interaction (ρ = -0.14 to -0.29, p < 0.01).</p><p><strong>Conclusion: </strong>Content about smoking cessation on mainstream Chinese short-video platforms is predominantly user-generated, and it is often fragmented, scientifically weak, and lacking elements of behavior-change psychology. Despite these shortcomings, high-quality videos still attract substantial user engagement. To harness the broad reach of these platforms, we propose constructing a four-party cooperation framework among government, platforms, experts, and users grounded in the \"Healthy China 2030\" initiative, establishing a quality-certification system, and incentivizing medical experts to produce rigorous, high-quality content.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between digestive diseases and symptomatic knee osteoarthritis in Chinese participants: a prospective cohort study.","authors":"Shile Chen, Youdi Liu, Daocheng Zhu, Wei Xu, Mingxuan Zheng, Aiwu Liu, Bing Wang, Suipeng Chen, Lin Jiao","doi":"10.1186/s12889-026-27690-w","DOIUrl":"https://doi.org/10.1186/s12889-026-27690-w","url":null,"abstract":"<p><strong>Background: </strong>Digestive diseases and symptomatic knee osteoarthritis (OA) frequently occur in older adults, yet prospective evidence clarifying their temporal relationship remains limited, particularly in Asian populations. This study examined the relationship between digestive diseases and the risk of incident symptomatic knee OA in a nationally representative cohort of middle‑aged and older Chinese adults.</p><p><strong>Methods: </strong>Data were obtained from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2018. A total of 6,281 adults without symptomatic knee OA at baseline were included. Digestive diseases were defined as exposure, and incident symptomatic knee osteoarthritis was the outcome of interest. Kaplan-Meier survival curves with log‑rank tests were used to compare cumulative incidence, and multivariable Cox proportional hazards models were applied to estimate hazard ratios. Sensitivity analyses included propensity score matching (PSM), prespecified subgroup analyses presented as forest plots, and E-value calculations.</p><p><strong>Results: </strong>A total of 6,281 participants were included in the analytical cohort (mean age, 58.6 ± 8.8 years; 53.5% women), with a median follow‑up of 84 months. Over the observation period, participants reporting digestive diseases experienced a markedly higher cumulative incidence of symptomatic knee OA compared with those without digestive conditions (31.4% versus 20.9%; log‑rank p < 0.01). After adjustment for potential confounders, multivariable Cox models indicated a higher risk of symptomatic knee OA among participants with digestive diseases (adjusted HR = 1.40; 95% CI: 1.25-1.57; p < 0.001). Similar effect estimates were obtained in the PSM (HR = 1.42; 95% CI: 1.23-1.64; p < 0.001). Subgroup analyses showed similar associations, with no statistically significant interactions detected. E‑value was 2.17.</p><p><strong>Conclusion: </strong>Digestive diseases are linked to a higher likelihood of symptomatic knee OA in this prospective cohort, supporting a temporal relationship between digestive disorders and the development of symptomatic knee OA.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}