BMC Public Health最新文献

{"title":"Publisher Correction: User-centered design to enhance university students' sex and menstrual education in South Korea: randomized controlled trial.","authors":"Hana Kim, Ji Woon Ko, Doyon Kim, Nagyeom Yoon, Jisan Lee","doi":"10.1186/s12889-025-22332-z","DOIUrl":"https://doi.org/10.1186/s12889-025-22332-z","url":null,"abstract":"","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"1218"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring experiences and perceptions of early withdrawal from a height-adjustable sit-to-stand desk intervention among South African office workers.","authors":"Merling Phaswana, Sunday O Onagbiye, Philippe Jean-Luc Gradidge","doi":"10.1186/s12889-025-22415-x","DOIUrl":"https://doi.org/10.1186/s12889-025-22415-x","url":null,"abstract":"<p><strong>Background: </strong>The increasing sedentary behaviour and burden of non-communicable diseases among office workers raise significant concerns. Height-adjustable sit-to-stand desks offer a potential solution, yet uptake remains challenging, limiting their effectiveness and long-term adoption. The experiences of office workers who withdrew from a height-adjustable sit-to-stand desk intervention need to be explored to inform program refinement.</p><p><strong>Methods: </strong>A qualitative approach was used, with pre-identified themes guiding data collection, while subthemes emerged inductively from transcripts and field notes. Twelve participants with a mean age of 46.0 years were conveniently sampled. These office workers withdrew from a height-adjustable standing desk randomised controlled trial and did not form any part of other studies. One-on-one semi-structured interviews guided data collection about the participants' experiences and reasons for early withdrawal from the intervention. Data were thematically analysed using Atlas.ti 23.</p><p><strong>Results: </strong>Most participants were female (n = 10, 83.3%). All participants completed high school, while 41.7% completed a postgraduate degree from a university and credit bureau company. Despite the participants' understanding of the benefits of height-adjustable sit-to-stand workstations, most of the participants discontinued the intervention due to perceived barriers that aligned with the themes: \"discomforts and dislikes\", \"applicability and practicality\", \"people's perception-i.e., what other people will say\" and \"transitioning to electronic sit-to-stand desks\".</p><p><strong>Conclusions: </strong>The findings of this study may assist in formulating a policy to improve compliance with height-adjustable sit-to-stand workstations in the workplace. Future studies should consider individual preferences, design, functionality, knowledge, and motivation to ensure effective implementation, utilisation, and compliance with height-adjustable sit-to-stand workstations.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"1209"},"PeriodicalIF":3.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The odds of developing asthma and wheeze among children and adolescents exposed to particulate matter: asystematic review and meta-analysis.","authors":"Awoke Keleb, Eyob Tilahun Abeje, Chala Daba, Abel Endawkie, Yawkal Tsega, Giziew Abere, Yimer Mamaye, Anmut Endalkachew Bezie","doi":"10.1186/s12889-025-22382-3","DOIUrl":"https://doi.org/10.1186/s12889-025-22382-3","url":null,"abstract":"<p><strong>Background: </strong>Exposure to air pollution specifically particulate matter causes significant health risk to children which increases their susceptibility to respiratory diseases.</p><p><strong>Objectives: </strong>This review aimed to pool the association between particulate matter exposure and childhood asthma and wheeze among children and adolescents.</p><p><strong>Methods: </strong>This review included observational study articles retrieved from electronic data bases such as PubMed, Google Scholar, Hinari, Science Direct, and Semantic Scholar from 1996 to June 17, 2024. Data were extracted and analyzed using Microsoft Excel 16 and STATA version 17, respectively. Joanna Briggs Institute evaluation criteria and I² test statistics were used for quality and heterogeneity assessment, respectively.</p><p><strong>Results: </strong>Fourty seven studies with a total of 417,874 of children and adolescents met the inclusion criteria. The pooled odd ratio (OR) of the association between Particulate Matter with a diameter of 10 micrometers or less (PM10) and Particulate Matter with a diameter of 2.5 micrometers or less (PM2.5) with asthma were 1.04 (95% CI: 1.03-1.06, p < 0.001) with significant extreme heterogeneity (I² = 82.7%, p < 0.001) and 1.05 (95% CI 1.04-1.07, p < 0.001) with high heterogeneity (I² = 80.6%, p < 0.001) among the included studies, respectively. The overall pooled estimate indicates a statistically significant association between PM10 and wheeze, with OR of 1.06 (95% CI: 1.05, 1.07) and moderate heterogeneity among included studies (I²=57.5%, p < 0.007) where as more association was observed between PM2.5 and wheeze with OR of 1.15. (95% CI: 1.10, 1.20) with an (I² =72.8%, p < 0.001).</p><p><strong>Conclusion: </strong>The findings of this systematic review and meta-analysis demonstrated a statistically significant association between exposure to both PM10 and PM2.5 and the occurrence of asthma and wheezing in children and adolescents. Both PM10 and PM2.5 are associated with increased odds of asthma and wheezing, with PM2.5 showing a stronger relationship. The significant levels of heterogeneity observed suggest variations across studies, which may be due to differences in study designs, exposure level and outcome measurement types. These findings indicate the need for strategies to reduce particle air pollution to mitigate its adverse effects on children's respiratory health.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"1225"},"PeriodicalIF":3.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using human-centered design to advance health literacy in local health department programming: a case study.","authors":"Adriane Ackerman, Brittany Nigon, Alexis Wait, Elham Ali, Ada M Wilkinson-Lee, Alexia Cohen, Meredith Jones, Imelda G Cortez, Katrina Kelly, Robert Fabricant, Jenitza Serrano-Feliciano, Jennifer Stanowski, Theresa Cullen","doi":"10.1186/s12889-025-22491-z","DOIUrl":"https://doi.org/10.1186/s12889-025-22491-z","url":null,"abstract":"<p><strong>Background: </strong>Human-centered design (HCD) and behavioral science are structured, evidence-based methodologies used to develop and evaluate community-driven interventions. While HCD focuses on deeply understanding user needs and co-designing solutions, behavioral science applies empirically tested principles to drive behavior change. Together, these methodologies enable the development of interventions that are both user-centered and behaviorally informed. The Pima County Health Department and project partners leveraged these collaborative methodologies to assemble a Community of Practice to improve health literacy and adherence to COVID-19 public health practices among Hispanic/Latine individuals of childbearing age and ability in Pima County.</p><p><strong>Methods: </strong>Human-centered design processes identified and evaluated barriers facing the target population. On the basis of these findings, two pilot interventions were implemented between July 2023 and November 2023: one in a clinical setting with 92 participants and another in a community setting with 207 participants. A mixed-methods approach was used to evaluate the impact of these pilots. Quantitatively, a pre-post evaluation and survey design estimated the effect of an intervention by comparing outcomes before and after implementation using paired t-test and chi-square tests. Qualitatively, structured post intervention interviews were conducted with participants who were randomly selected based upon their initial consent and willingness to participate.</p><p><strong>Results: </strong>Participants in the clinical and community pilots perceived fewer barriers to health-seeking behaviors after the intervention. Both pilots increased participants' confidence in health-seeking behaviors (p < 0.01). Only the clinical pilot resulted in an increase in health literacy. In the clinical pilot, the number of unvaccinated participants decreased, and the number of participants who reported needing a booster increased. The community pilot did not find a statistically significant difference in COVID-19 vaccine uptake.</p><p><strong>Conclusions: </strong>Integrating human-centered design and behavioral science into public health interventions can improve health literacy and confidence in health-seeking behaviors among historically and contemporarily excluded populations. Local health departments can use these methods to develop multicomponent interventions that foster mutual co-invention with communities and improve population health outcomes. Future research should focus on long-term impacts and explore broader applications of these approaches in different contexts.</p><p><strong>Trial registration: </strong>This project received University of Arizona IRB review and approval. This study was not considered a randomized controlled trial and did not require registration.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"1207"},"PeriodicalIF":3.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of introvert and extrovert personalities in perception of COVID-19's impact, psychological state, knowledge, infection, and preparedness preferences.","authors":"Jiaying Li, Daniel Yee Tak Fong, Mandy Man Ho, Edmond Pui Hang Choi, Kris Yuet Wan Lok, Jung Jae Lee, WenJie Duan, Janet Yuen Ha Wong, Chia-Chin Lin","doi":"10.1186/s12889-025-22293-3","DOIUrl":"https://doi.org/10.1186/s12889-025-22293-3","url":null,"abstract":"<p><strong>Background: </strong>The role of introversion and extraversion in shaping pandemic responses remains understudied in the field of public health. This study aimed to comprehensively investigate differences in perceptions of COVID-19's impact, psychological status, knowledge of COVID-19, infection rate, and preferred preparations among introverts and extroverts.</p><p><strong>Methods: </strong>This study utilized a cross-sectional design. From May to June 2022, an online survey was conducted, involving 1,990 adults in Hong Kong. Regression analyses were employed to identify personality differences across 58 outcomes of interest. To account for multiplicity, adjustments were made using the Holm-Bonferroni method.</p><p><strong>Results: </strong>Extroverts reported a greater increase in having a meal at home (adjusted p [adj.p] < 0.001), while introverts' sleep quality decreased more (adj.p < 0.001). Although no statistical difference was detected between the decrease they showed in emotional stress (adj.p = 1.000) and mental burden (adj.p = 1.000), introverts had higher levels of anxiety (adj.p = 0.006), depression (adj.p < 0.001), and fear (adj.p = 0.026), whereas extroverts had stronger out of control feelings (adj.p = 0.010). Besides, extroverts had higher self-rated knowledge on COVID-19 knowledge (adj.p = 0.016) and prevention (adj.p < 0.001). Moreover, extroverts perceived higher importance in online consultation with doctors, instant personalized health by online chatbot, online courses, instant streaming courses, medicine delivery, online shopping, and food delivery (all adj.p < 0.05).</p><p><strong>Conclusions: </strong>Introverts could benefit most from interventions addressing sleep quality, anxiety, depression, fear, and knowledge promotion about COVID-19, while extroverts could benefit most from approaches that address feeling out of control. Extroverts had higher preferences for online consultations, instant personalized health via online chatbots, streaming courses, online courses, and medicine delivery, emphasizing the importance of considering personality in field of telemedicine, e-health, and remote medicine practice. These findings have important implications for pandemic response and preparedness, highlighting the role of personality in public health emergencies.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"1203"},"PeriodicalIF":3.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating fragmented services: a gender-based violence (GBV) critical feminist analysis of women's experiences engaging with health and social supports in three Canadian cities.","authors":"Katherine Rudzinski, Lara F Hudspith, Adrian Guta, Scott Comber, Linda Dewar, Wendy Leiper, Kim Hawkins, Lady Laforet, Rajwant Raji Mangat, Phoebe M Long, Ingrid Handlovsky, Vicky Bungay","doi":"10.1186/s12889-025-21919-w","DOIUrl":"https://doi.org/10.1186/s12889-025-21919-w","url":null,"abstract":"<p><strong>Background: </strong>Gender-based violence (GBV) remains a pervasive public health crisis with devastating impacts on women's health and well-being. Women experiencing GBV face considerable barriers accessing appropriate and timely health and social services. This study explored women's experiences with health and social services in three Canadian cities to understand critical challenges and strengths in service provision for women experiencing GBV.</p><p><strong>Methods: </strong>In-depth interviews were conducted with self-identifying women (n = 21) who had accessed health or social care services and with service providers (n = 25) in three Canadian cities between February 2021 and November 2022. Women's interviews focused on experiences engaging with services including what worked well, the challenges they faced, and their recommendations to enhance service delivery to women experiencing violence. Staff interviews focused on their experiences of providing services within their organization, and the strengths and challenges in providing services to women within their community. Data were analyzed using reflexive thematic analysis with a gender-based violence critical feminist lens.</p><p><strong>Results: </strong>We organized the findings into three interrelated themes. First our results show how the systems within which health and social services are organized, are not designed to meet women's complex needs, with rigid structures, siloed services, and stigmatizing cultures creating significant barriers. Second, the data illustrate how service providers support and empower women through practices such as providing key information, assisting with administrative tasks, offering material resources, and addressing discrimination through advocacy and accompaniment. Third, our findings demonstrate how building an effective working relationship characterized by trust, non-judgment, and collaboration is crucial for service engagement and women's overall well-being.</p><p><strong>Conclusions: </strong>Findings illuminate critical public health challenges as women navigate fragmented services across multiple and siloed systems not designed to meet their complex needs. There is an urgent need for systemic change to create more integrated, responsive support systems for women experiencing GBV. This includes addressing underlying structures perpetuating gender inequities and violence. Facilitating safe access to holistic services that consider women's preferences is crucial. Effective working relationships built on trust, respect, and power-sharing are key to supporting women's agency and addressing their interconnected needs.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"1213"},"PeriodicalIF":3.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Sepsis brought him to his knees\": exploring the lived experiences and perspectives of sepsis survivors and family members to inform a sepsis public education campaign in Canada.","authors":"Jeanna Parsons Leigh, Rebecca Brundin-Mather, Deirdre Walsh, Sara J Mizen, Cynthia Sriskandarajah, Marie-Maxime Bergeron, Denise E Werner, Kirsten M Fiest","doi":"10.1186/s12889-025-22344-9","DOIUrl":"https://doi.org/10.1186/s12889-025-22344-9","url":null,"abstract":"<p><strong>Background: </strong>Sepsis is a life-threatening complication of the body's response to fighting an infection. The global burden of sepsis is incredibly high, accounting for an estimated 20% percent of all global deaths as well as high hospitalization costs and long-term multifaceted sequelae. As most sepsis starts in the community, public knowledge of sepsis is essential to rapid identification and medical intervention. The current study is part of multi-study collaborative research program. Following a scoping review and national survey to assess public knowledge of sepsis, we conducted focus groups to explore the lived experiences and perspectives of sepsis survivors and family members with the goal to inform development of a sepsis public education campaign.</p><p><strong>Methods: </strong>We co-designed a focus group guide covering three broad discussion topics: circumstances leading to sepsis, impacts of sepsis, and interactions with healthcare providers. Participants were purposively recruited through the previous national survey and through Sepsis Canada communications. We used a hybrid deductive-inductive approach to code transcripts and generate themes related to developing a sepsis public education campaign.</p><p><strong>Results: </strong>We conducted 11 focus groups with 32 participants. Participants' median age was 53 years (Interquartile Range = 48, 64). Three-quarters (n = 23/32; 72%) self-identified as women, and all participants reported having some post-secondary education. All but one sepsis survivor were adults at the time of their diagnosis. We synthesized three overarching campaign messages from participant's accounts of profound physical and mental impacts of sepsis and perceptions of health system failures: (1) sepsis is serious and common, (2) know the signs of sepsis, and (3) be health attentive and advocate health needs. Potential barriers to message uptake were: (1) sepsis is not well-known or easily understood, (2) perceptions that sepsis is not personally relevant, and (3) health messaging fatigue. Suggestions to effectively hook and draw public attention to sepsis centered on using personal stories and partnering with other health campaigns.</p><p><strong>Conclusions: </strong>Our analysis of participant's lived experiences with sepsis suggest that public communications should aim to (1) improve sepsis symptom recognition, (2) foster perceptions that sepsis is personally relevant, and (3) cultivate and support health advocacy.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"1211"},"PeriodicalIF":3.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health seeking behaviour of caregivers of children under five and its determinants in Ho West and Adaklu districts, Volta Region, Ghana: a community-based cross-sectional study.","authors":"Joseph Osarfo, Gifty Dufie Ampofo, Harry Kwami Tagbor","doi":"10.1186/s12889-025-22393-0","DOIUrl":"https://doi.org/10.1186/s12889-025-22393-0","url":null,"abstract":"<p><strong>Background: </strong>Despite gains made in child survival, morbidity and mortality remain high in sub-Saharan Africa. Seeking healthcare at health facilities for sick children under-five within 24 h of onset of symptoms is key to mitigating severe morbidity and mortality. However, literature on this outcome is limited and poses challenges for monitoring caregivers' adherence to prompt health seeking behaviour. This study assessed the prevalence and determinants of prompt caregiver health seeking behaviour (HSB) for sick under-fives in two districts in the Volta Region of Ghana.</p><p><strong>Methods: </strong>The study was conducted among 770 caregivers/children in the Ho West and Adaklu districts of the Volta Region. Data on caregiver and child characteristics and knowledge of childhood illness symptoms/ signs among others were obtained. Summary statistics were presented as frequencies and percentages. Logistic regression was used to assess for association between prompt HSB and independent variables including caregiver and child socio-demographics. Odds ratios were presented with 95% confidence intervals at a statistical significance of p < 0.05 in the final model.</p><p><strong>Results: </strong>Almost 93% (714/770) of the caregivers were females while about three-quarters (559/767) were aged 20-39 years. The mean age of the study children was 24.1 months. Of caregivers who sought formal health care the last time their children fell ill, only about 59% (337/573) did so within 24 h of symptoms onset. Less than 10% (52/770) of caregivers had adequate knowledge of childhood danger signs while about 64% (492/770) had decision-making capacity regarding sending a sick child to a health facility. Male children had twice the odds of caregivers' prompt HSB compared to females [AOR 2.02 95% CI: 1.24, 3.27; p = 0.004]. Fourth-born or higher birth order children had 56% reduced odds of prompt HSB [AOR 0.44 95% CI: 0.26, 0.75; p = 0.003].</p><p><strong>Conclusion: </strong>About 60% of those who sought formal care for their sick children did so promptly and this was influenced by the sex and birth order of the child. Public health managers in the study area must promote interventions to improve prompt caregiver HSB, especially for children of higher birth orders. Community education is needed to minimize 'discrimination' against the girl child as far as prompt HSB is concerned.</p>","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"1219"},"PeriodicalIF":3.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Publisher Correction: Navigating menstrual stigma and norms: a qualitative study on young people's menstrual experiences and strategies for improving menstrual health.","authors":"Eva Åkerman, Anna Wängborg, Maria Persson, Renita Sörensdotter, Marie Klingberg-Allvin","doi":"10.1186/s12889-025-22328-9","DOIUrl":"https://doi.org/10.1186/s12889-025-22328-9","url":null,"abstract":"","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"1212"},"PeriodicalIF":3.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for progression to type 2 diabetes in prediabetes: a systematic review and meta-analysis.","authors":"Shengying Hu, Wenting Ji, Yizhu Zhang, Wendi Zhu, Hongyu Sun, Yumei Sun","doi":"10.1186/s12889-025-21404-4","DOIUrl":"https://doi.org/10.1186/s12889-025-21404-4","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Prediabetes is the earliest identifiable stage of glycemic dysregulation, and its progression can be delayed by effective control of risk factors. Currently, various risk factors for the progression from prediabetes to type 2 diabetes mellitus (T2DM) need to be further summarized.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This systematic evaluation of the risk factors for the progression of prediabetes to type 2 diabetes mellitus provides a theoretical basis for early recognition and intervention. The meta-analysis identifies the Fatty Liver Index as a significant risk factor [OR = 6.14, 95% CI (5.22, 7.22)] for the progression from prediabetes to type 2 diabetes, highlighting its predictive value.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;PubMed, Web of Science, Embase, The Cochrane Library, CNKI, WANFANG, and VIP databases were searched to collect cohort studies on risk factors for progressing to type 2 diabetes in prediabetes from inception to February 15, 2024. STATA 17.0 was used for Meta-analysis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 59 studies were included, all of which were of medium to high quality. The factors were categorized into four major groups: sociodemographic factors, lifestyle factors, psychosocial factors, and comorbidities and clinical indicators. Meta-analysis results showed that sociodemographic factors [age [OR = 1.03, 95% CI (1.01, 1.04)], family history [OR = 1.48, 95% CI (1.36, 1.61)], male sex [OR = 1.13, 95% CI (1.08, 1.19)], high BMI [OR = 1.21, 95% CI (1.15, 1.27)], high waist circumference [OR = 1.49, 95% CI (1.23, 1.79)], and high waist-to-hip ratio [OR = 2.44, 95% CI (2.17, 2.74)]]. Lifestyle factors included a lack of physical exercise [OR = 1.86, 95% CI (1.19, 2.88)], smoking [OR = 1.31, 95% CI (1.22, 1.41)], and moderate physical activity [OR = 0.24, 95% CI (0.09, 0.67)]. Psychosocial factors included anxiety [OR = 2.61, 95% CI (1.36, 5.00)], depression [OR = 1.88, 95% CI (1.35, 2.61)], and social deprivation level 4 [OR = 1.15, 95% CI (1.13, 1.18)]. Comorbidities and clinical indicators included hypertension [OR = 1.41, 95% CI (1.33, 1.50)], high triglycerides [OR = 1.25, 95% CI (1.10, 1.43)], high cholesterol [OR = 1.09, 95% CI (1.06, 1.12)], fatty liver index [OR = 6.14, 95% CI (5.22, 7.22)], low HDL-C [OR = 1.13, 95% CI (1.09, 1.36)], and high blood glucose levels [OR = 1.01, 95% CI (1.01, 1.02)].&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;This study found that age, male sex, positive family history of type 2 diabetes, high BMI, unhealthy lifestyle, anxiety, depression, high blood pressure, high triglycerides, and a high fatty liver index are risk factors for the progression from prediabetes to type 2 diabetes and should be given sufficient attention. Moderate physical activity and Low HDL-C are protective factors. Future studies should also increase follow-up, explore the best diagnostic criteria for prediabetes, and fully consider the definitions of various factors. The study was registered","PeriodicalId":9039,"journal":{"name":"BMC Public Health","volume":"25 1","pages":"1220"},"PeriodicalIF":3.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}