Biointerface Research in Applied Chemistry最新文献_第5页

Extracellular Expression of Recombinant Kex2 Protease in Pichia pastoris BG10 重组Kex2蛋白酶在毕赤酵母BG10中的胞外表达

Biointerface Research in Applied Chemistry Pub Date : 2022-09-24 DOI: 10.33263/briac134.360

引用次数: 0

One-pot Hydrothermal Synthesis of Vanadium Dioxide Nanoparticles 二氧化钒纳米粒子的一锅水热合成

Biointerface Research in Applied Chemistry Pub Date : 2022-09-24 DOI: 10.33263/briac134.361

引用次数: 0

The Efficiency of Saccharomyces Cerevisiae as an Antifungal and Antimycotoxigenic Agent 酿酒酵母菌的抑菌抑毒作用研究

Biointerface Research in Applied Chemistry Pub Date : 2022-09-17 DOI: 10.33263/briac134.354

{"title":"The Efficiency of Saccharomyces Cerevisiae as an Antifungal and Antimycotoxigenic Agent","authors":"","doi":"10.33263/briac134.354","DOIUrl":"https://doi.org/10.33263/briac134.354","url":null,"abstract":"Aflatoxins (AFs) and zearalenone (ZEN) are the most predominant mycotoxins in various food and feed. Therefore, this study aimed to estimate the antifungal activity of Saccharomyces cerevisiae strains and to study their ability to remove aflatoxin B1 (AFB1) and zearalenone (ZEN) in vitro. Data revealed that S. cerevisiae NRLL Y-12633 showed higher antifungal activity compared to S. cerevisiae NRRL Y-1089. On the other hand, S. cerevisiae suspension exhibited higher antifungal activity than S. cerevisiae supernatant. Concerning the removal of AFB1, results indicated that after 30 min. S. cerevisiae NRRL Y-1089 displayed a higher ability to remove AFB1 at a concentration of 5.0 µg/mL with a percentage of reduction reaching 87.20% than S. cerevisiae NRRL Y-12633, which removed 21.00%. As for the removal of ZEN, results showed that after 30 min. S. cerevisiae NRRL Y-12633 successfully removed ZEN at a concentration of 5.0 µg/mL by 94.80%, whereas S. cerevisiae NRRL Y-1089 removed ZEN by 91.80%. Results also indicated that the removal of AFB1 increased by increasing the incubation time, whereas the removal of ZEN decreased by increasing the incubation time. Therefore, it could be concluded that S. cerevisiae strains could be applied as an additive to decrease the concentration of mycotoxins in food and feed.","PeriodicalId":9026,"journal":{"name":"Biointerface Research in Applied Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45354577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Uncovering the Anticancer Potential of Phytomedicine and Polyherbal’s Synergism against Cancer – A Review 揭示植物药和多药抗癌协同作用的潜力——综述

Biointerface Research in Applied Chemistry Pub Date : 2022-09-17 DOI: 10.33263/briac134.356

{"title":"Uncovering the Anticancer Potential of Phytomedicine and Polyherbal’s Synergism against Cancer – A Review","authors":"","doi":"10.33263/briac134.356","DOIUrl":"https://doi.org/10.33263/briac134.356","url":null,"abstract":"Cancer is a dreadful disease; many researchers successfully aimed to find a strategy to successfully eliminate cancer with minimal side effects. Herbal medicine allows us to attain sickness relief while avoiding side effects. Several herbal compounds have been discovered to have an anti-cancer effect by inducing apoptosis, antioxidant activity, and inhibiting, activating cancer-causing, and suppressing genes and proteins. The existence of active phytochemicals that treat a variety of ailments contributes to medicinal plants' pharmacological efficacy. Since commonly used modern chemical treatments for cancer possess severe side effects, identifying an alternative treatment with fewer side effects and effective illness relief is critical. This review reveals that aromatic phytocompounds account for 90 percent of anti-cancer action with most terpenoids and phenolics. Each anti-cancer phytocompound works in a distinct way to stop cancer from spreading. Polyherbal formulations are more effective than single herbs at expressing anti-cancer and other activities because they can act on multiple targets simultaneously, have multiple mechanisms for a single ailment, inhibit disease resistance development and enhance treatment activity through synergism. When using synergic herbal substances in the right ratio, a polyherbal formulated medicine can be used as a commercial drug following successful clinical trials for cancer therapy.","PeriodicalId":9026,"journal":{"name":"Biointerface Research in Applied Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43285453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Impact of Mutations in the SARS-CoV-2 Spike RBD Region of BA.1 and BA.2 Variants on its Interaction with ACE2 Receptor Protein SARS-CoV-2 ba1和ba2变异体刺突RBD区突变对ACE2受体蛋白相互作用的影响

Biointerface Research in Applied Chemistry Pub Date : 2022-09-17 DOI: 10.33263/briac134.358

C. Das, V. S. Mattaparthi

引用次数: 0

Study of Thermodynamic Parameters for Nano Zinc Sulfate in the Presence of Proline (amino acid) in Mixed MeOH-H2O Solvents at Different Temperatures 不同温度下脯氨酸(氨基酸)存在下纳米硫酸锌在甲醇-水混合溶剂中的热力学参数研究

Biointerface Research in Applied Chemistry Pub Date : 2022-09-17 DOI: 10.33263/briac134.359

引用次数: 0

Computational Insights in the Spectrophotometrically Analyzed Niobium (V)- 3-Hydroxy-2-(4-methylphenyl)-4H-chromen-4-one Complex using DFT Method DFT法分光光度法分析铌（V）-3-羟基-2-（4-甲基苯基）-4H-甲烯-4-酮配合物的计算见解

Biointerface Research in Applied Chemistry Pub Date : 2022-09-17 DOI: 10.33263/briac134.357

{"title":"Computational Insights in the Spectrophotometrically Analyzed Niobium (V)- 3-Hydroxy-2-(4-methylphenyl)-4H-chromen-4-one Complex using DFT Method","authors":"","doi":"10.33263/briac134.357","DOIUrl":"https://doi.org/10.33263/briac134.357","url":null,"abstract":"Using 3-hydroxy-2-(4-methylphenyl)-4H-chromen-4-one (HMC) as a complexing agent in an acidic medium, a simple, quick, highly sensitive, and selective approach for the extractive spectrophotometric measurement of micro quantities of niobium (V) is developed. The yellowish 1:3 complex can be extracted 100 % in dichloromethane (DCM), attaining maximum absorbance in the wavelength range 388-407 nm. At 400 nm, the selected wavelength, the approach follows a linear calibration curve up to 2.2 g Nb (V) ml-1 and 0.395-1.78 ppm Nb (V) as identified from the Ringbom Plot with molar absorptivity, specific absorptivity, and Sandell's sensitivity of 4.926 × 104 l mol-1 cm-1, 0.5302 ml g-1 cm-1 and 0.0019 µg Nb cm-2, respectively. With a correlation coefficient of 0.9994, the linear regression equation is Y = 0.514 X + 0.016. The method's detection limit is 0.0698 µg ml-1. The presented determination of pentavalent niobium is unaffected by 33 cations and 22 anions/complexing agents. The approach has good reproducibility and can be used to determine niobium in a satisfactory manner. The analytical study has been correlated well with the theoretical approach of Density Functional Theory (DFT) for quantum chemical calculations. DFT effectively helped determine and interpret the chemical behavior of the obtained Nb(V)-HMC complex, explaining its stability and reactivity pattern.","PeriodicalId":9026,"journal":{"name":"Biointerface Research in Applied Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44987108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, Characterization and Electrochemical Detection of Glucose and H2O2, Molecular Docking and Biological Inspection of Transition Metal Complexes of Novel Ligand 2-[(5-methyl-1,3-benzoxazol-2-yl)sulfanyl]acetohydrazide 2-[(5-甲基-1,3-苯并恶唑-2-酰基)磺酰]乙酰肼过渡金属配合物的合成、表征及电化学检测

Biointerface Research in Applied Chemistry Pub Date : 2022-09-17 DOI: 10.33263/briac134.353

{"title":"Synthesis, Characterization and Electrochemical Detection of Glucose and H2O2, Molecular Docking and Biological Inspection of Transition Metal Complexes of Novel Ligand 2-[(5-methyl-1,3-benzoxazol-2-yl)sulfanyl]acetohydrazide","authors":"","doi":"10.33263/briac134.353","DOIUrl":"https://doi.org/10.33263/briac134.353","url":null,"abstract":"A renowned pharmacophore and structure of great relevance to various fields, benzoxazole is a prominent member of the heterocyclic family. Aside from that, metal complexes can enhance the drug action and efficacy of the organic therapeutic agent. These insights led us to conduct research, including synthesizing and characterizing benzoxazole-derived ligand and metal complexes, assessing their pharmacological properties, and the potential use of the metal complex as a biosensor for sensing glucose and H2O2. The novel ligand MBA and its transition metal complexes are synthesized and characterized for their geometrical composition by varied physical and spectroscopic procedures. Antimicrobial potency was measured by the well diffusion method and antioxidant levels by the DPPH technique. A molecular docking study and MTTtest were carried out to assess anticancer activity for MCF-7 and Hela cell lines. The study results show that MBA bear bidentate coordination and octahedral geometry are ideal for the coordination of metals. The Co(II)MBA/GCE sensor demonstrated astounding electrochemical activity for glucose, and H2O2 and Ni(II) and Cu(II) compounds had impressive antimicrobial and cytotoxic potency, whereas Co(II) and Ni(II) complex were stronger antioxidant agents.","PeriodicalId":9026,"journal":{"name":"Biointerface Research in Applied Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48458877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Investigating a Boron Nitride Plate for the Formaldehyde Adsorption: Density Functional Theory Calculations 氮化硼吸附甲醛板的密度泛函理论计算

Biointerface Research in Applied Chemistry Pub Date : 2022-09-17 DOI: 10.33263/briac134.346

{"title":"Investigating a Boron Nitride Plate for the Formaldehyde Adsorption: Density Functional Theory Calculations","authors":"","doi":"10.33263/briac134.346","DOIUrl":"https://doi.org/10.33263/briac134.346","url":null,"abstract":"A boron nitride (BN) plate was investigated in this work for adsorbing the formaldehyde (Frm) substance by performing the density functional theory (DFT) calculations. The singular models of BN and Frm were optimized first, and their combinations were re-optimized next to obtain Frm@BN complexes; F1 and F2 were found. To manage the interaction processes, an iron (Fe) atom was inserted in the center of a small plate. The results showed the benefits of such atomic insertion for approaching the goal of this work. Details of interactions were analyzed, and the results show the existence of two interactions for each of obtained Frm@BN bimolecular models. The model with O…Fe, and H…N interactions (F1) was placed at a higher level of strength than the model with the existence of H…Fe and H…N interactions (F2). Accordingly, energy levels of characteristic frontier molecular orbitals and their related features affirmed the impacts of complex formations leading to the possibility of running diagnostic processes. Additionally, the role of the Fe-doped region was dominant in conducting the adsorption processes, and the results of both F1 and F2 complexes revealed such importance. Consequently, the stabilized models regarding the energies and interactions details affirmed this achievement for proposing the formations of Frm@BN complexes for environmental applications.","PeriodicalId":9026,"journal":{"name":"Biointerface Research in Applied Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44912223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Recent Development of Synthetic Strategies Towards the Synthesis of Azomethine Analogues: A Brief Review 甲亚胺类似物合成策略的最新进展——综述

Biointerface Research in Applied Chemistry Pub Date : 2022-09-17 DOI: 10.33263/briac134.350

引用次数: 0