Uncovering the Anticancer Potential of Phytomedicine and Polyherbal’s Synergism against Cancer – A Review

Abstract

Cancer is a dreadful disease; many researchers successfully aimed to find a strategy to successfully eliminate cancer with minimal side effects. Herbal medicine allows us to attain sickness relief while avoiding side effects. Several herbal compounds have been discovered to have an anti-cancer effect by inducing apoptosis, antioxidant activity, and inhibiting, activating cancer-causing, and suppressing genes and proteins. The existence of active phytochemicals that treat a variety of ailments contributes to medicinal plants' pharmacological efficacy. Since commonly used modern chemical treatments for cancer possess severe side effects, identifying an alternative treatment with fewer side effects and effective illness relief is critical. This review reveals that aromatic phytocompounds account for 90 percent of anti-cancer action with most terpenoids and phenolics. Each anti-cancer phytocompound works in a distinct way to stop cancer from spreading. Polyherbal formulations are more effective than single herbs at expressing anti-cancer and other activities because they can act on multiple targets simultaneously, have multiple mechanisms for a single ailment, inhibit disease resistance development and enhance treatment activity through synergism. When using synergic herbal substances in the right ratio, a polyherbal formulated medicine can be used as a commercial drug following successful clinical trials for cancer therapy.