Biopolymers最新文献_第5页

Starch-based films affected by the addition of collagen from Prochilodus magdalenae residues and HPMC: Application in Andean blackberry (Rubus glaucus Benth) coatings 淀粉基薄膜在添加了来自大肠杆菌（Prochilodus magdalenae）残留物的胶原蛋白和 HPMC 后的影响：在安第斯黑莓（Rubus glaucus Benth）涂层中的应用。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-23 DOI: 10.1002/bip.23601

Vanessa Acevedo-Puello, Paula Gómez-Contreras, Rodrigo Ortega-Toro

{"title":"Starch-based films affected by the addition of collagen from Prochilodus magdalenae residues and HPMC: Application in Andean blackberry (Rubus glaucus Benth) coatings","authors":"Vanessa Acevedo-Puello, Paula Gómez-Contreras, Rodrigo Ortega-Toro","doi":"10.1002/bip.23601","DOIUrl":"10.1002/bip.23601","url":null,"abstract":"Starch-based films offer the advantages of biodegradability, edibility, barrier properties, flexibility, and adaptability. This study compared the physicochemical properties of starch-based films by adding raw fish collagen and hydroxypropylmethylcellulose (HPMC). The tensile properties were evaluated, and the interaction with water was analyzed. Barrier properties, such as water vapor and oxygen permeability, were examined, and optical properties, such as gloss and good internal transmittance, were evaluated. The films were evaluated as coatings on Andean blackberries (Rubus glaucus Benth) for 2 weeks at 85% RH and 25°C. The results showed that the inclusion of collagen caused a reduction in the tensile strength and elastic modulus of the films. Also, the formulation with the highest collagen concentration (F7) exhibited the lowest weight loss and water vapor permeability, also it had the highest collagen concentration and showed the highest reduction in Xw and WAC, with values of 0.048 and 0.65 g water/g dry film, respectively. According to analyzing the optical properties, F1 presented the highest bright-ness and transmittance values, with 18GU and 82 nm values, respectively. In general, the films and coatings are alternatives to traditional packaging materials to prolong the shelf life of these fruits.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 5","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of porous poly(L-lactide-co-ε-caprolactone) micropowder for microbubble effect and ultrasound-mediated drug delivery 制备多孔聚（L-乳酸-共ε-己内酯）微粉，用于微泡效应和超声介导的药物输送

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-16 DOI: 10.1002/bip.23587

Jin Ik Lim

{"title":"Fabrication of porous poly(L-lactide-co-ε-caprolactone) micropowder for microbubble effect and ultrasound-mediated drug delivery","authors":"Jin Ik Lim","doi":"10.1002/bip.23587","DOIUrl":"10.1002/bip.23587","url":null,"abstract":"Biodegradable elastic poly(L-lactide-co-ε-caprolactone) (PLCL) copolymer (50:50, lactide:caprolactone molar ratio) was synthesized and porous PLCL micropowders was fabricated by a simple method involving rapid cooling of 0.1, 0.5, and 1% (wt/vol) PLCL/dioxane spray into liquid nitrogen. The physicochemical properties of the porous PLCL micropowders were examined by measuring their pore size, pore morphology, and microbead size using a scanning electron microscopy (SEM) and dye and temozolomide (TMZ)-release testing under ultrasound. Human U-87MG, glioblastoma (GBM) cell culture tests were performed to evaluate cell cytotoxicity by released drug from PLCL micropowders. In this study, the porous PLCL micropowders prepared from 1 wt%/vol% PLCL solutions showed a highly porous structure, satisfactory mechanical properties, and optimal drug release efficiency compared with those produced from 0.1 or 0.5 wt%/vol% solutions. The results of the accumulated release test with the results of the absorbance of the dye initially applied, it was confirmed that more than 80% of the added dye was trapped inside the micropowder, and clearly GBM cytotoxicity effect could be observed by the released TMZ. The drug release system using micropowders and ultrasound can be applied as a drug supply system for various diseases such as brain tumors with low drug permeability.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 5","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140943885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extraction of cellulose from halophytic plants for the synthesis of a novel biocomposite 从盐生植物中提取纤维素，用于合成新型生物复合材料。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-15 DOI: 10.1002/bip.23586

Uroosa Ejaz, Yusra Shafquat, Muhammad Sohail, Aizaz Ahmed Shaikh, Muhammad Daniyal Arain, Tehmees Ahmed, Abdullah K. Alanazi

{"title":"Extraction of cellulose from halophytic plants for the synthesis of a novel biocomposite","authors":"Uroosa Ejaz, Yusra Shafquat, Muhammad Sohail, Aizaz Ahmed Shaikh, Muhammad Daniyal Arain, Tehmees Ahmed, Abdullah K. Alanazi","doi":"10.1002/bip.23586","DOIUrl":"10.1002/bip.23586","url":null,"abstract":"Cellulose nanofibers, a sustainable and promising material with widespread applications, exhibit appreciable strength and excellent mechanical and physicochemical properties. The preparation of cellulosic nanofibers from food or agricultural residue is not sustainable. Therefore, this study was designed to use three halophytic plants (Cressa cretica, Phragmites karka, and Suaeda fruticosa) to extract cellulose for the subsequent conversion to cellulosic nanofibers composites. The other extracted biomass components including lignin, hemicellulose, and pectin were also utilized to obtain industrially valuable enzymes. The maximum pectinase (31.56 IU mL−1), xylanase (35.21 IU mL−1), and laccase (15.89 IU mL−1) were produced after the fermentation of extracted pectin, hemicellulose, and lignin from S. fruticosa, P. karka, and C. cretica, respectively. Cellulose was methylated (with a degree of substitution of 2.4) and subsequently converted into a composite using polyvinyl alcohol. Scanning electron microscopy and Fourier-transform infrared spectroscopy confirmed the successful synthesis of the composites. The composites made up of cellulose from C. cretica and S. fruticosa had a high tensile strength (21.5 and 15.2 MPa) and low biodegradability (47.58% and 44.56%, respectively) after dumping for 3 months in soil, as compared with the composite from P. karka (98.79% biodegradability and 4.9 MPa tensile strength). Moreover, all the composites exhibited antibacterial activity against gram-negative bacteria (Escherichia coli and Klebsiella pneumoniae) and gram-positive bacteria (Staphylococcus aureus). Hence, this study emphasizes the possibility for various industrial applications of biomass from halophytic plants.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140921067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A facile and scalable method to synthesize PEGylated PDMAEMA for gene delivery 用于基因递送的 PEG 化 PDMAEMA 的简便、可扩展合成方法

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-02 DOI: 10.1002/bip.23584

Jie Dou, Shupei Yu, Yuanwei Zhang

引用次数: 0

Synthesis of PEGylated amphiphilic block copolymers with pendant linoleic moieties by combining ring-opening polymerization and click chemistry 结合开环聚合和点击化学，合成具有亚油酸悬垂分子的 PEG 化两亲嵌段共聚物

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-04-29 DOI: 10.1002/bip.23582

Julian D. Porras, Ivonne L. Diaz, Leon D. Perez

{"title":"Synthesis of PEGylated amphiphilic block copolymers with pendant linoleic moieties by combining ring-opening polymerization and click chemistry","authors":"Julian D. Porras, Ivonne L. Diaz, Leon D. Perez","doi":"10.1002/bip.23582","DOIUrl":"10.1002/bip.23582","url":null,"abstract":"This study focused on synthesizing and characterizing PEGylated amphiphilic block copolymers with pendant linoleic acid (Lin) moieties as an alternative to enhance their potential in drug delivery applications. The synthesis involved a two-step process, starting with ring-opening polymerization of ε-caprolactone (CL) and propargylated cyclic carbonate (MCP) to obtain PEG-b-P(CL-co-MCP) copolymers, which were subsequently modified via click chemistry. Various reaction conditions were explored to improve the yield and efficiency of the click chemistry step. The use of anisole as a solvent, N-(3-azidopropyl)linoleamide as a substrate, and a reaction temperature of 60°C proved to be highly efficient, achieving nearly 100% conversion at a low catalyst concentration. The resulting copolymers exhibited controlled molecular weights and low polydispersity, confirming the successful synthesis. Furthermore, click chemistry allows for the attachment of Lin moieties to the copolymer, enhancing its hydrophobic character, as deduced from their significantly lower critical micelle concentration than that of traditional PEG-b-PCL systems, which is indicative of enhanced stability against dilution. The modified copolymers exhibited improved thermal stability, making them suitable for applications that require high processing temperatures. Dynamic light scattering and transmission electron microscopy confirmed the formation of micellar structures with sizes below 100 nm and minimal aggregate formation. Additionally, 1H NMR spectroscopy in deuterated water revealed the presence of core-shell micelles, which provided higher kinetic stability against dilution.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140810105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustainable strategies towards better utilization of synthetic polymers 更好地利用合成聚合物的可持续战略。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-04-26 DOI: 10.1002/bip.23581

G. Shanthi, J. Beula Isabel, Rosbin Thankachan, M. Premalatha

{"title":"Sustainable strategies towards better utilization of synthetic polymers","authors":"G. Shanthi, J. Beula Isabel, Rosbin Thankachan, M. Premalatha","doi":"10.1002/bip.23581","DOIUrl":"10.1002/bip.23581","url":null,"abstract":"The abstract provides an overview of a study focused on analyzing diverse strategies to achieve sustainable utilization of synthetic polymers through effective waste management. The escalating global consumption of synthetic polymers has precipitated a concerning increase in plastic waste and environmental degradation. To address this challenge, novel materials with specified application goals, such as engineered plastic, have been developed and are intended for recycling and reuse. Despite the reuse and recycling, when plastic gets disposed into the environment, the degradation properties of plastics render a direct disposal hazard, posing a significant environmental threat. To mitigate these issues, the concept of replacing specific monomers of engineered synthetic plastics with bio-alternatives or blending them with other polymers to enhance sustainability and environmental compatibility has emerged. In this study, Acrylonitrile Butadiene Styrene (ABS) plastic is the focal material, and three distinct investigations were conducted. First, replacing ABS plastic's butadiene monomer with natural rubber was explored for its properties and environmental impact. Second, ABS plastic was blended with virgin, recycled, and bio-alternatives of PET (polyethylene terephthalate) and PVC (polyvinyl chloride) polymers. Lastly, recycled ABS blended with recycled PET and PVC was analyzed for mechanical properties. Comparative assessments of these blends were made based on mechanical properties, carbon emissions, and cost-effectiveness. The study determined that the r-ABS/r-PVC (recycled) blend exhibited the most favorable characteristics for practical application.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140652219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydroxyapatite-loaded macroporous calcium alginate hydrogels: Preparation, characterization, and in vitro evaluation 负载羟基磷灰石的大孔海藻酸钙水凝胶：制备、表征和体外评估。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-04-25 DOI: 10.1002/bip.23583

Maria Drozdova, Alika Makhonina, Daria Gladkikh, Alexander Artyukhov, Leonid Bryukhanov, Yaroslav Mezhuev, Vladimir Lozinsky, Elena Markvicheva

引用次数: 0

State diagrams of green peas (Pisum sativum L.) powders with different maltodextrin additions 添加不同麦芽糊精的青豌豆（Pisum sativum L.）粉末的状态图

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-04-15 DOI: 10.1002/bip.23580

Anna Stępień, Mariusz Witczak

{"title":"State diagrams of green peas (Pisum sativum L.) powders with different maltodextrin additions","authors":"Anna Stępień, Mariusz Witczak","doi":"10.1002/bip.23580","DOIUrl":"10.1002/bip.23580","url":null,"abstract":"The purpose of this study was to examine the effect of maltodextrin addition on the physical stability of powdered green peas. The evaluation of the physical state of the material was based on the equilibrium water content of the monolayer (Xm) and the glass transition temperatures of the powders at room temperature (Tg) and in the frozen state (Tg'). Graphical sorption characteristic at 25°C was determined using static—gravimetric method while capacity of the monolayer values was calculated from the mathematical GAB model. Differential scanning calorimetry was carried out in order to determine glass transition lines and freezing curves which combine together were used to plot state diagrams. Relationship between Tg and solid content were shown by using Gordon–Taylor model. Freezing data were modeled employing the Clausius–Clapeyron equation and its development—Chen model. Sorption isotherms showed sigmoidal shape characteristic for high-molecular weight materials. Monolayer moisture content varied between 0.047 and 0.106 g water/g solids. The glass transition temperature of anhydrous green peas increased in from 89.9 to 175.6°C while Tg′ value changed from −43.4 to −26.6°C to as a result of 75% polysaccharide addition. The ultimate maximum-freeze-concentration conditions of the powders were observed in range from 0.783 to 0.814 g solids/g sample. Monolayer capacity, Tg and Tg′ values increased with increasing maltodextrin amount in the sample which indicates that the addition of starch hydrolysate has a beneficial effect on the stability of powders stored frozen and at room temperature.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140582782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial wound dressing with cross-linked electrospun surface from reduced graphene oxide doped polyvinyl alcohol/sodium caseinate blends 掺杂还原氧化石墨烯的聚乙烯醇/酪蛋白酸钠混合物交联电纺表面的抗菌伤口敷料

IF 2.9 4区生物学

Biopolymers Pub Date : 2024-04-05 DOI: 10.1002/bip.23579

Sema Samatya Yilmaz, Ayse Aytac

{"title":"Antibacterial wound dressing with cross-linked electrospun surface from reduced graphene oxide doped polyvinyl alcohol/sodium caseinate blends","authors":"Sema Samatya Yilmaz, Ayse Aytac","doi":"10.1002/bip.23579","DOIUrl":"10.1002/bip.23579","url":null,"abstract":"In this study, a new biomaterial with polyvinyl alcohol (PVA)/sodium caseinate (SodCa)/reduced graphene oxide (rGO) structure was developed. Antibacterial effective nanofibers were successfully produced by electrospinning method from 1%, 3%, 5%, and 7% rGO added PVA/SodCa (60:40, w:w) solution mixtures prepared for use as modern wound dressings. To create a usage area, especially in exuding wounds, hydrophilic PVA/SodCa/rGO electrospun mats were cross-linked by dipping them in a glutaraldehyde (GLA) bath. The surface micrographs of all nanofibers were homogeneous and smooth. rGO-doped biomaterials were obtained as thin nanofibers in the range of 301–348 nm. Nanofibers, which were completely soluble in water, after cross-linking preserved their existence in the range of 87%–81% at the end of the 24th hour in distilled water. It was reported that these biomaterials that persist in an aqueous environment show swelling behavior in the range of 275%–608%. The porosity of uncross-linked pure PVA/SodCa nanofibers increased by 46.75% after cross-linking. Moreover, the tensile strength of cross-linked PVA/SodCa electrospun mats increased in the presence of rGO. Provided that wound dressing is done every 24 h with 3% rGO-doped PVA/SodCa nanofiber and provided that wound dressing is done every 48 h with 5% rGO-doped PVA/SodCa nanofiber showed antibacterial activity against S. aureus as 99.38% and 99.55%, respectively.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140582657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polymers and their engineered analogues for ocular drug delivery: Enhancing therapeutic precision 用于眼部给药的聚合物及其工程类似物：提高治疗精度

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-04-05 DOI: 10.1002/bip.23578

Arpon Biswas, Shivansh Kumar, Abhijit Deb Choudhury, Amol Chhatrapati Bisen, Sachin Nashik Sanap, Sristi Agrawal, Anjali Mishra, Sarvesh Kumar Verma, Mukesh Kumar, Rabi Sankar Bhatta

{"title":"Polymers and their engineered analogues for ocular drug delivery: Enhancing therapeutic precision","authors":"Arpon Biswas, Shivansh Kumar, Abhijit Deb Choudhury, Amol Chhatrapati Bisen, Sachin Nashik Sanap, Sristi Agrawal, Anjali Mishra, Sarvesh Kumar Verma, Mukesh Kumar, Rabi Sankar Bhatta","doi":"10.1002/bip.23578","DOIUrl":"10.1002/bip.23578","url":null,"abstract":"Ocular drug delivery is constrained by anatomical and physiological barriers, necessitating innovative solutions for effective therapy. Natural polymers like hyaluronic acid, chitosan, and gelatin, alongside synthetic counterparts such as PLGA and PEG, have gained prominence for their biocompatibility and controlled release profiles. Recent strides in polymer conjugation strategies have enabled targeted delivery through ligand integration, facilitating tissue specificity and cellular uptake. This versatility accommodates combined drug delivery, addressing diverse anterior (e.g., glaucoma, dry eye) and posterior segment (e.g., macular degeneration, diabetic retinopathy) afflictions. The review encompasses an in-depth exploration of each natural and synthetic polymer, detailing their individual advantages and disadvantages for ocular drug delivery. By transcending ocular barriers and refining therapeutic precision, these innovations promise to reshape the management of anterior and posterior segment eye diseases.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140582789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0