Harnessing Nature's Power: Plant and Polymeric-Based Antibacterials as Potential Therapeutics for Infectious Skin Wound Healing

IF 3.2 4区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biopolymers Pub Date : 2025-03-03 DOI:10.1002/bip.70007

Rasoul Kheradmandi, Sepehr Zamani, Mohammad Kamalabadi Farahani, Arian Ehterami, Majid Salehi

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引用次数: 0

Abstract

This comprehensive review explores the potential of plant- and biopolymeric-based antibacterials as innovative therapeutic agents for infectious skin wound healing. By researching the antibacterial properties of various plants, the review highlights their application in skin tissue engineering. Beyond reviewing antibacterial plant extracts, the article delves into the limitations these natural compounds face, such as hydrophilicity, drug release rates, cell attachment, and scaffold stability when integrated into tissue engineering constructs. The review also emphasizes the role of biopolymeric materials, hydrogel optimization, and crosslinkers to improve scaffold performance. This review provides a roadmap for future research by addressing critical factors in scaffold construction. In the end, it aims to guide the development of more effective wound dressings and tissue scaffolds, combining the natural power of plants with advanced biopolymeric materials for enhanced wound healing therapies.

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来源期刊

Biopolymers 生物-生化与分子生物学

CiteScore

5.30

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： Founded in 1963, Biopolymers publishes strictly peer-reviewed papers examining naturally occurring and synthetic biological macromolecules. By including experimental and theoretical studies on the fundamental behaviour as well as applications of biopolymers, the journal serves the interdisciplinary biochemical, biophysical, biomaterials and biomedical research communities.