Beilstein Journal of Nanotechnology最新文献_第8页

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis. 应用纳米药物治疗肝纤维化的最新进展。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-08-23 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.89

Damai Ria Setyawati, Fransiska Christydira Sekaringtyas, Riyona Desvy Pratiwi, A'liyatur Rosyidah, Rohimmahtunnissa Azhar, Nunik Gustini, Gita Syahputra, Idah Rosidah, Etik Mardliyati, Tarwadi, Sjaikhurrizal El Muttaqien

{"title":"Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis.","authors":"Damai Ria Setyawati, Fransiska Christydira Sekaringtyas, Riyona Desvy Pratiwi, A'liyatur Rosyidah, Rohimmahtunnissa Azhar, Nunik Gustini, Gita Syahputra, Idah Rosidah, Etik Mardliyati, Tarwadi, Sjaikhurrizal El Muttaqien","doi":"10.3762/bjnano.15.89","DOIUrl":"10.3762/bjnano.15.89","url":null,"abstract":"Over recent decades, nanomedicine has played an important role in the enhancement of therapeutic outcomes compared to those of conventional therapy. At the same time, nanoparticle drug delivery systems offer a significant reduction in side effects of treatments by lowering the off-target biodistribution of the active pharmaceutical ingredients. Cancer nanomedicine represents the most extensively studied nanotechnology application in the field of pharmaceutics and pharmacology since the first nanodrug for cancer treatment, liposomal doxorubicin (Doxil®), has been approved by the FDA. The advancement of cancer nanomedicine and its enormous technological success also included various other target diseases, including hepatic fibrosis. This confirms the versatility of nanomedicine for improving therapeutic activity. In this review, we summarize recent updates of nanomedicine platforms for improving therapeutic efficacy regarding liver fibrosis. We first emphasize the challenges of conventional drugs for penetrating the biological barriers of the liver. After that, we highlight design principles of nanocarriers for achieving improved drug delivery of antifibrosis drugs through passive and active targeting strategies.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1105-1116"},"PeriodicalIF":2.6,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11346304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications. 揭示海藻酸盐纳米材料在传感技术和智能传输应用中的潜力。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-08-22 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.88

Shakhzodjon Uzokboev, Khojimukhammad Akhmadbekov, Ra'no Nuritdinova, Salah M Tawfik, Yong-Ill Lee

{"title":"Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications.","authors":"Shakhzodjon Uzokboev, Khojimukhammad Akhmadbekov, Ra'no Nuritdinova, Salah M Tawfik, Yong-Ill Lee","doi":"10.3762/bjnano.15.88","DOIUrl":"10.3762/bjnano.15.88","url":null,"abstract":"Sensors are applied to many fields nowadays because of their high sensitivity, low cost, time-saving, user-friendly, and excellent selectivity. Current biomedical and pharmaceutical science has one focus on developing nanoparticle-based sensors, especially biopolymeric nanoparticles. Alginate is a widely used biopolymer in a variety of applications. The hydrogel-forming characteristic, the chemical structure with hydroxy and carboxylate moieties, biocompatibility, biodegradability, and water solubility of alginate have expanded opportunities in material and biomedical sciences. Recently, research on alginate-based nanoparticles and their applications has begun. These materials are gaining popularity because of their wide usage potential in the biomedical and pharmaceutical fields. Many review papers describe applications of alginate in the drug delivery field. The current study covers the structural and physicochemical properties of alginate-based nanoparticles. The prospective applications of alginate-based nanomaterials in various domains are discussed, including drug delivery and environmental sensing applications for humidity, heavy metals, and hydrogen peroxide. Moreover, biomedical sensing applications of alginate-based nanoparticles regarding various analytes such as glucose, cancer cells, pharmaceutical drugs, and human motion will also be reviewed in this paper. Future research scopes highlight existing challenges and solutions.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1077-1104"},"PeriodicalIF":2.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11346306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Signal generation in dynamic interferometric displacement detection. 动态干涉位移检测中的信号生成。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-08-20 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.87

Knarik Khachatryan, Simon Anter, Michael Reichling, Alexander von Schmidsfeld

引用次数: 0

Effect of wavelength and liquid on formation of Ag, Au, Ag/Au nanoparticles via picosecond laser ablation and SERS-based detection of DMMP. 波长和液体对通过皮秒激光烧蚀形成银、金、银/金纳米粒子的影响以及基于 SERS 的 DMMP 检测。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-08-19 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.86

Sree Satya Bharati Moram, Chandu Byram, Venugopal Rao Soma

{"title":"Effect of wavelength and liquid on formation of Ag, Au, Ag/Au nanoparticles via picosecond laser ablation and SERS-based detection of DMMP.","authors":"Sree Satya Bharati Moram, Chandu Byram, Venugopal Rao Soma","doi":"10.3762/bjnano.15.86","DOIUrl":"10.3762/bjnano.15.86","url":null,"abstract":"The present study investigates the effects of input wavelength (1064, 532, and 355 nm) and surrounding liquid environment (distilled water and aqueous NaCl solution) on the picosecond laser ablation on silver (Ag), gold (Au), and Ag/Au alloy targets. The efficacy of the laser ablation technique was meticulously evaluated by analyzing the ablation rates, surface plasmon resonance peak positions, and particle size distributions of the obtained colloids. The nanoparticles (NPs) were characterized using the techniques of UV-visible absorption, transmission electron microscopy, and energy-dispersive X-ray spectroscopy. Furthermore, NPs of various sizes ranging from 6 to 35 nm were loaded onto a filter paper by a simple and effective drop-casting approach to achieve flexible surface-enhanced Raman spectroscopy (SERS) substrates/sensors. These substrates were tested using a simple, portable Raman device to identify various hazardous chemicals (malachite green, methyl salicylate, and thiram). The stability of the substrates was also systematically investigated by determining the decay percentages in the SERS signals over 60 days. The optimized SERS substrate was subsequently employed to detect chemical warfare agent (CWA) simulants such as methyl salicylate (a CWA simulant for sulfur mustard) and dimethyl methyl phosphonate (has some structural similarities to the G-series nerve agents) at different laser excitations (325, 532, and 633 nm). A notably higher SERS efficiency for CWA simulants was observed at a 325 nm Raman excitation. Our findings reveal that a higher ablation yield was observed at IR irradiation than those obtained at the other wavelengths. A size decrease of the NPs was noticed by changing the liquid environment to an electrolyte. These findings have significant implications for developing more efficient and stable SERS substrates for chemical detection applications.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1054-1069"},"PeriodicalIF":2.6,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11346305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interface properties of nanostructured carbon-coated biological implants: an overview. 纳米结构碳涂层生物植入物的界面特性：综述。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.85

Mattia Bartoli, Francesca Cardano, Erik Piatti, Stefania Lettieri, Andrea Fin, Alberto Tagliaferro

引用次数: 0

Bolometric IR photoresponse based on a 3D micro-nano integrated CNT architecture. 基于三维微纳集成碳纳米管结构的波长红外光响应。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-08-15 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.84

Yasameen Al-Mafrachi, Sandeep Yadav, Sascha Preu, Jörg J Schneider, Oktay Yilmazoglu

{"title":"Bolometric IR photoresponse based on a 3D micro-nano integrated CNT architecture.","authors":"Yasameen Al-Mafrachi, Sandeep Yadav, Sascha Preu, Jörg J Schneider, Oktay Yilmazoglu","doi":"10.3762/bjnano.15.84","DOIUrl":"10.3762/bjnano.15.84","url":null,"abstract":"A new 3D micro-nano integrated M-shaped carbon nanotube (CNT) architecture was designed and fabricated. It is based on vertically aligned carbon nanotube arrays composed of low-density, mainly double-walled CNTs with simple lateral external contacts to the surroundings. Standard optical lithography techniques were used to locally tailor the width of the vertical block structure. The complete sensor system, based on a broadband blackbody absorber region and a high-resistance thermistor region, can be fabricated in a single chemical vapor deposition process step. The thermistor resistance is mainly determined by the high junction resistances of the adjacent aligned CNTs. This configuration also provides low lateral thermal conductivity and a high temperature coefficient of resistance (TCR). These properties are advantageous for new bolometric sensors with high voltage responsivity and broadband absorption from the infrared (IR) to the terahertz spectrum. Preliminary performance evaluations have shown current and voltage responsivities of 2 mA/W and 30 V/W, respectively, in response to IR (980 nm) absorption for a 20 × 20 μm2 device. The device exhibits an exceptionally fast response time of ≈0.15 ms, coupled with a TCR of -0.91 %/K. These attributes underscore its high operating speed and responsivity, respectively. In particular, the device maintains excellent thermal stability and reliable operation at elevated temperatures in excess of 200 °C, extending its potential utility in challenging environmental conditions. This design allows for further device miniaturization using optical lithography techniques. Its unique properties for mass production through large-scale integration techniques make it important for real-time broadband imaging systems.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1030-1040"},"PeriodicalIF":2.6,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11331537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Entry of nanoparticles into cells and tissues: status and challenges. 纳米颗粒进入细胞和组织：现状与挑战。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-08-12 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.83

Kirsten Sandvig, Tore Geir Iversen, Tore Skotland

引用次数: 0

Atomistic insights into the morphological dynamics of gold and platinum nanoparticles: MD simulations in vacuum and aqueous media. 对金和铂纳米粒子形态动力学的原子洞察：真空和水介质中的 MD 模拟。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-08-07 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.81

Evangelos Voyiatzis, Eugenia Valsami-Jones, Antreas Afantitis

{"title":"Atomistic insights into the morphological dynamics of gold and platinum nanoparticles: MD simulations in vacuum and aqueous media.","authors":"Evangelos Voyiatzis, Eugenia Valsami-Jones, Antreas Afantitis","doi":"10.3762/bjnano.15.81","DOIUrl":"10.3762/bjnano.15.81","url":null,"abstract":"The thermal response of gold and platinum spherical nanoparticles (NPs) upon cooling is studied through atomistic molecular dynamics simulations. The goal is to identify the morphological transformations occurring in the nanomaterials as well as to quantify their dependence on temperature, chemistry, and NP size. For diameters smaller than 3 nm, the transition temperature from a melted/amorphous to a highly crystalline state varies considerably with NP size. For larger NPs, the transition temperature is almost diameter-independent, yet it differs considerably from the transition temperature of the respective bulk materials. The platinum NPs possess a higher level of crystallinity than the gold counterparts under the same conditions because of the stronger cohesive forces that drive the crystallization process. This observation is also supported by the simulated X-ray powder diffraction patterns of the nanomaterials. The larger NPs have a multifaceted crystal surface, and their shape remains almost constant regardless of temperature variations. The smaller NPs have a smoother and more spherical surface, and their shape varies greatly with temperature. By studying the variation of nano-descriptors commonly employed in QSAR models, a qualitative picture of the NPs' toxicity and reactivity emerges: Small/hot NPs are likely more toxic than their large/cold counterparts. Because of the small size of the NPs considered, the observed structural modifications are challenging to be studied by experimental techniques. The present approach can be readily employed to study other metallic and metal oxide nanomaterials.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"995-1009"},"PeriodicalIF":2.6,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141970539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent progress on field-effect transistor-based biosensors: device perspective. 基于场效应晶体管的生物传感器的最新进展：器件视角。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-08-06 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.80

Billel Smaani, Fares Nafa, Mohamed Salah Benlatrech, Ismahan Mahdi, Hamza Akroum, Mohamed Walid Azizi, Khaled Harrar, Sayan Kanungo

{"title":"Recent progress on field-effect transistor-based biosensors: device perspective.","authors":"Billel Smaani, Fares Nafa, Mohamed Salah Benlatrech, Ismahan Mahdi, Hamza Akroum, Mohamed Walid Azizi, Khaled Harrar, Sayan Kanungo","doi":"10.3762/bjnano.15.80","DOIUrl":"10.3762/bjnano.15.80","url":null,"abstract":"Over the last few decades, field-effect transistor (FET)-based biosensors have demonstrated great potential across various industries, including medical, food, agriculture, environmental, and military sectors. These biosensors leverage the electrical properties of transistors to detect a wide range of biomolecules, such as proteins, DNA, and antibodies. This article presents a comprehensive review of advancements in the architectures of FET-based biosensors aiming to enhance device performance in terms of sensitivity, detection time, and selectivity. The review encompasses an overview of emerging FET-based biosensors and useful guidelines to reach the best device dimensions, favorable design, and realization of FET-based biosensors. Consequently, it furnishes researchers with a detailed perspective on design considerations and applications for future generations of FET-based biosensors. Finally, this article proposes intriguing avenues for further research on the topology of FET-based biosensors.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"977-994"},"PeriodicalIF":2.6,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141970541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond biomimicry - next generation applications of bioinspired adhesives from microfluidics to composites. 超越仿生学--从微流控技术到复合材料，生物启发粘合剂的下一代应用。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.79

Dan Sameoto

引用次数: 0