Beilstein Journal of Nanotechnology最新文献

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Nanoscale capacitance spectroscopy based on multifrequency electrostatic force microscopy. 基于多频静电力显微镜的纳米级电容光谱。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-05-08 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.49
Pascal N Rohrbeck, Lukas D Cavar, Franjo Weber, Peter G Reichel, Mara Niebling, Stefan A L Weber
{"title":"Nanoscale capacitance spectroscopy based on multifrequency electrostatic force microscopy.","authors":"Pascal N Rohrbeck, Lukas D Cavar, Franjo Weber, Peter G Reichel, Mara Niebling, Stefan A L Weber","doi":"10.3762/bjnano.16.49","DOIUrl":"https://doi.org/10.3762/bjnano.16.49","url":null,"abstract":"<p><p>We present multifrequency heterodyne electrostatic force microscopy (MFH-EFM) as a novel electrostatic force microscopy method for nanoscale capacitance characterization at arbitrary frequencies above the second cantilever resonance. Besides a high spatial resolution, the key advantage of the multifrequency approach of MFH-EFM is that it measures the second-order capacitance gradient at almost arbitrary frequencies, enabling the measurement of the local dielectric function over a wide range of frequencies. We demonstrate the reliable operation of MFH-EFM using standard atomic force microscopy equipment plus an external lock-in amplifier up to a frequency of 5 MHz, which can in principle be extended to gigahertz frequencies and beyond. Our results show a significant reduction of signal background from long-range electrostatic interactions, resulting in highly localized measurements. Combined with refined tip-sample capacitance models, MFH-EFM will enhance the precision of quantitative studies on dielectric effects in nanoscale systems across materials science, biology, and nanotechnology, complementing established methods in the field.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"637-651"},"PeriodicalIF":2.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12067100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A formulation containing Cymbopogon flexuosus essential oil: improvement of biochemical parameters and oxidative stress in diabetic rats. 香蒲精油配方对糖尿病大鼠生化指标及氧化应激的改善。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-05-07 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.48
Ailton Santos Sena-Júnior, Cleverton Nascimento Santana Andrade, Pedro Henrique Macedo Moura, Jocsã Hémany Cândido Dos Santos, Cauãn Torres Trancoso, Eloia Emanuelly Dias Silva, Deise Maria Rego Rodrigues Silva, Ênio Pereira Telles, Luiz André Santos Silva, Isabella Lima Dantas Teles, Sara Fernanda Mota de Almeida, Daniel Alves de Souza, Jileno Ferreira Santos, Felipe José Aidar Martins, Ana Mara de Oliveira E Silva, Sandra Lauton-Santos, Guilherme Rodolfo Souza de Araujo, Cristiane Bani Correa, Rogéria De Souza Nunes, Lysandro Pinto Borges, Ana Amélia Moreira Lira
{"title":"A formulation containing <i>Cymbopogon flexuosus</i> essential oil: improvement of biochemical parameters and oxidative stress in diabetic rats.","authors":"Ailton Santos Sena-Júnior, Cleverton Nascimento Santana Andrade, Pedro Henrique Macedo Moura, Jocsã Hémany Cândido Dos Santos, Cauãn Torres Trancoso, Eloia Emanuelly Dias Silva, Deise Maria Rego Rodrigues Silva, Ênio Pereira Telles, Luiz André Santos Silva, Isabella Lima Dantas Teles, Sara Fernanda Mota de Almeida, Daniel Alves de Souza, Jileno Ferreira Santos, Felipe José Aidar Martins, Ana Mara de Oliveira E Silva, Sandra Lauton-Santos, Guilherme Rodolfo Souza de Araujo, Cristiane Bani Correa, Rogéria De Souza Nunes, Lysandro Pinto Borges, Ana Amélia Moreira Lira","doi":"10.3762/bjnano.16.48","DOIUrl":"https://doi.org/10.3762/bjnano.16.48","url":null,"abstract":"<p><p>Diabetes mellitus (DM) is a highly prevalent public health problem characterized by hyperglycemia that causes complications due to the generation of reactive oxygen species and oxidative damage. Studies have shown that essential oils containing citral, such as lemongrass, have various biological activities, including bactericidal, antiviral, antifungal, antioxidant, and hypoglycemic effects. Therefore, this study aims to obtain a microemulsified formulation containing the essential oil of <i>Cymbopogon flexuosus</i> (EOCF) and to evaluate its antioxidant and antidiabetic activity in diabetic rats. The microemulsion (ME) was obtained after consulting the corresponding pseudoternary phase diagram and showed stability, isotropy, Newtonian behavior, nanometric size (15.2 nm), and pH 4.2. Both EOCF and the ME showed high antioxidant activity, but the ME resulted in greater antioxidant activity, potentiating the activity of isolated EOCF. Finally, male Wistar rats (3 months old, 200-250 g) with streptozotocin-induced type-1 DM were supplemented with EOCF and ME (32 mg/kg) for 21 days. Both EOCF and ME supplementation resulted in reduced blood glucose levels and improved lipid profiles when compared to the control group. Additionally, the ME was able to provide additional benefits, such as reduced liver damage, improved renal function, reduced systemic inflammation, and increased high-density lipoprotein levels. Overall, the results show that EOCF was efficiently incorporated into the microemulsion, improving its antioxidant activity and showing promising results for use in the treatment of DM via the oral route.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"617-636"},"PeriodicalIF":2.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12067095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Focused ion and electron beams for synthesis and characterization of nanomaterials. 聚焦离子束和电子束用于纳米材料的合成和表征。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.47
Aleksandra Szkudlarek
{"title":"Focused ion and electron beams for synthesis and characterization of nanomaterials.","authors":"Aleksandra Szkudlarek","doi":"10.3762/bjnano.16.47","DOIUrl":"https://doi.org/10.3762/bjnano.16.47","url":null,"abstract":"","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"613-616"},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polyurethane/silk fibroin-based electrospun membranes for wound healing and skin substitute applications. 用于伤口愈合和皮肤替代品的聚氨酯/丝素基静电纺丝膜。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-24 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.46
Iqra Zainab, Zohra Naseem, Syeda Rubab Batool, Muhammad Waqas, Ahsan Nazir, Muhammad Anwaar Nazeer
{"title":"Polyurethane/silk fibroin-based electrospun membranes for wound healing and skin substitute applications.","authors":"Iqra Zainab, Zohra Naseem, Syeda Rubab Batool, Muhammad Waqas, Ahsan Nazir, Muhammad Anwaar Nazeer","doi":"10.3762/bjnano.16.46","DOIUrl":"https://doi.org/10.3762/bjnano.16.46","url":null,"abstract":"<p><p>The importance of electrospun membranes for biomedical applications has increased, especially when it comes to skin regeneration and wound healing. This review presents the production and applications of electrospun membranes based on polyurethane (PU) and silk fibroin (SF) and highlights their benefits as a skin substitute. This review also highlights the electrospinning technique used to prepare nanofibers for these biomedical applications. Silk, well-known for its excellent biocompatibility, biodegradability, structural properties, and low immunogenic response, is extensively investigated by addressing its molecular structure, composition, and medical uses. PU is a candidate for potential biomedical applications because of its strength, flexibility, biocompatibility, cell-adhesive properties, and high resistance to biodegradation. PU combined with silk offers a number of enhanced properties. The study offers a comprehensive overview of the advanced developments and applications of PU/SF composites, highlighting their significant potential in wound healing. These composite membranes present promising advancements in wound healing and skin regeneration by combining the unique properties of silk and PU, opening up the possibilities for innovative treatments.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"591-612"},"PeriodicalIF":2.6,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility analysis of carbon nanofiber synthesis and morphology control using a LPG premixed flame. 液化石油气预混火焰合成纳米碳纤维的可行性分析及形貌控制。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-23 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.45
Iftikhar Rahman Bishal, Muhammad Hilmi Ibrahim, Norikhwan Hamzah, Mohd Zamri Mohd Yusop, Faizuan Bin Abdullah, I Putu Tedy Indrayana, Mohd Fairus Mohd Yasin
{"title":"Feasibility analysis of carbon nanofiber synthesis and morphology control using a LPG premixed flame.","authors":"Iftikhar Rahman Bishal, Muhammad Hilmi Ibrahim, Norikhwan Hamzah, Mohd Zamri Mohd Yusop, Faizuan Bin Abdullah, I Putu Tedy Indrayana, Mohd Fairus Mohd Yasin","doi":"10.3762/bjnano.16.45","DOIUrl":"https://doi.org/10.3762/bjnano.16.45","url":null,"abstract":"<p><p>Flame synthesis using liquefied petroleum gas (LPG) as the precursor gas to produce carbon nanofibers (CNFs) is an economical alternative to conventional chemical vapor deposition methods using single-component fuels such as methane and ethylene. Though LPG is a commercially viable source for carbon-based nanomaterials, the understanding of the effects of a LPG flame on CNF growth is very limited. Therefore, the present study is to analyze the feasibility of CNF growth in a premixed LPG flame using a one-dimensional flame at varying equivalence ratios. The effects of flame equivalence ratio on the CNF morphology and crystallinity are then analyzed systematically. In the present study, a diffusion flame was used to check the stability of the flame at different flow rates, followed by establishing a premixed flat flame of LPG. An optimum height above burner of 10 mm at which the temperature is around 650 °C was used in the synthesis process. Zirconia beads impregnated with nickel nitrate catalyst have been employed. Dense CNF growth with an average diameter of 77.9 nm was observed at an equivalence ratio of 1.8; as the equivalence ratio was reduced to 1.6, the average diameter of CNF increased by 46% to 114 nm, with amorphous carbon observed. The said observation is due to the effects of the increased flame temperature as the equivalence ratio approaches stoichiometry conditions from the rich side. This increases the nucleation rate, which in turn increases the catalyst particle size and the amount of free carbon atoms, producing CNFs with larger diameters and amorphous carbon. According to Raman analysis, the grown CNFs have a high number of defects, which may be good for applications where defective nanomaterials are desirable to improve the component performance. The work has proven that flame synthesis of CNFs using commercial LPG is feasible, paving the way for further exploration into cost-efficient CNF production with potential industrial applications.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"581-590"},"PeriodicalIF":2.6,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy. 靶向淀粉样蛋白-β低聚物的纳米材料:阿尔茨海默病诊断和治疗的最新进展和未来方向。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-22 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.44
Shiwani Randhawa, Trilok Chand Saini, Manik Bathla, Rahul Bhardwaj, Rubina Dhiman, Amitabha Acharya
{"title":"Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy.","authors":"Shiwani Randhawa, Trilok Chand Saini, Manik Bathla, Rahul Bhardwaj, Rubina Dhiman, Amitabha Acharya","doi":"10.3762/bjnano.16.44","DOIUrl":"https://doi.org/10.3762/bjnano.16.44","url":null,"abstract":"<p><p>The amyloid cascade hypothesis posits that amyloid-β oligomers (AβOs) are the most neurotoxic species in Alzheimer's disease (AD). These oligomers, characterized by their high β-sheet content, have been shown to significantly disrupt cell membranes, induce local inflammation, and impair autophagy processes, which collectively contribute to neuronal loss. As such, targeting AβOs specifically, rather than solely focusing on amyloid-β fibrils (AβFs), may offer a more effective therapeutic approach for AD. Recent advances in detection and diagnosis have emphasized the importance of accurately identifying AβOs in patient samples, enhancing the potential for timely intervention. In recent years, nanomaterials (NMs) have emerged as promising agents for addressing AβOs regarding their multivalent interactions, which can more effectively detect and inhibit AβO formation. This review provides an in-depth analysis of various nanochaperones developed to target AβOs, detailing their mechanisms of action and therapeutic potential via focusing on two main strategies, namely, disruption of AβOs through direct interaction and the inhibition of AβO nucleation by binding to intermediates of the oligomerization process. Evidence from in vivo studies indicate that NMs hold promise for ameliorating AD symptoms. Additionally, the review explores the different interaction mechanisms through which nanoparticles exhibit their inhibitory effects on AβOs, providing insights into their potential for clinical application. This comprehensive overview highlights the current advancements in NM-based therapies for AD and outlines future research directions aimed at optimizing these innovative treatments.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"561-580"},"PeriodicalIF":2.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrieval of B1 phase from high-pressure B2 phase for CdO nanoparticles by electronic excitations in Cd x Zn1- x O composite thin films. Cd x Zn1- x O复合薄膜中B1相从高压B2相中回收CdO纳米颗粒
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-17 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.43
Arkaprava Das, Marcin Zając, Carla Bittencourt
{"title":"Retrieval of B1 phase from high-pressure B2 phase for CdO nanoparticles by electronic excitations in Cd <i><sub>x</sub></i> Zn<sub>1-</sub> <i><sub>x</sub></i> O composite thin films.","authors":"Arkaprava Das, Marcin Zając, Carla Bittencourt","doi":"10.3762/bjnano.16.43","DOIUrl":"https://doi.org/10.3762/bjnano.16.43","url":null,"abstract":"<p><p>This study investigates the recovery of the B1 phase from the high-pressure B2 phase, at atmospheric pressure, in cadmium oxide (CdO) nanoparticles incorporated within sol-gel synthesized Cd <i><sub>x</sub></i> Zn<sub>1-</sub> <i><sub>x</sub></i> O (<i>x</i> = 0.40) composite thin films. The recovery process is investigated using electronic excitations as an effective tool. Exposure to 120 MeV silver ion irradiation results in the complete amorphization of the B2 phase in CdO nanoparticles, while the crystalline hexagonal wurtzite phase of zinc oxide (ZnO) remains intact. In contrast, 80 MeV oxygen ion irradiation preserves the B2 phase and facilitates the reemergence of the B1 phase. The partial damage caused by electronic energy loss during oxygen ion irradiation in the willemite Zn<sub>2</sub>SiO<sub>4</sub> phase is identified as a trigger for the B1 to B2 phase transformation in CdO nanoparticles, enabling the recovery of the B1 phase. The diminishing local pressure exerted by the Zn<sub>2</sub>SiO<sub>4</sub> phase on CdO nanoparticles during oxygen ion irradiation leads to the coexistence of both B1 and B2 phases. X-ray absorption near-edge spectra (XANES) reveal minimal changes in the intensity of the spike-like Zn <i>L</i> <sub>3,2</sub> pre-edge feature associated with the Zn<sub>2</sub>SiO<sub>4</sub> phase under oxygen ion irradiation, while it entirely disappears with silver ion irradiation, confirming the amorphization of the Zn<sub>2</sub>SiO<sub>4</sub> phase. Complementary observations from X-ray photoelectron spectroscopy (XPS), specifically O 1s and Si 2p peaks in XPS spectra, support these findings. Additionally, the track diameter in CdO subjected to 120 MeV silver ion irradiation is calculated to be approximately 8 nm using an inelastic thermal spike simulation code. This study elucidates the intriguing reappearance of the B1 phase under oxygen ion irradiation and highlights the radiation stability of the B2 phase through diverse characterization techniques, demonstrating the potential reversibility of the B1 to B2 phase transformation induced by ion irradiation.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"551-560"},"PeriodicalIF":2.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12018908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus. 碳丝网印刷电极上功能化金纳米花:一种生物感应甲型H1N1流感病毒血凝素蛋白的电化学平台。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-16 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.42
Carlos Enrique Torres-Méndez, Sharmilee Nandi, Klara Martinovic, Patrizia Kühne, Yifan Liu, Sam Taylor, Maria Lysandrou, Maria Ines Berrojo Romeyro Mascarenhas, Viktoria Langwallner, Javier Enrique Sebastián Alonso, Ivana Jovanovic, Maike Lüftner, Georgia-Vasiliki Gkountana, David Bern, Abdul-Raouf Atif, Ehsan Manouchehri Doulabi, Gemma Mestres, Masood Kamali-Moghaddam
{"title":"Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus.","authors":"Carlos Enrique Torres-Méndez, Sharmilee Nandi, Klara Martinovic, Patrizia Kühne, Yifan Liu, Sam Taylor, Maria Lysandrou, Maria Ines Berrojo Romeyro Mascarenhas, Viktoria Langwallner, Javier Enrique Sebastián Alonso, Ivana Jovanovic, Maike Lüftner, Georgia-Vasiliki Gkountana, David Bern, Abdul-Raouf Atif, Ehsan Manouchehri Doulabi, Gemma Mestres, Masood Kamali-Moghaddam","doi":"10.3762/bjnano.16.42","DOIUrl":"https://doi.org/10.3762/bjnano.16.42","url":null,"abstract":"<p><p>An electrochemical biosensor based on modified carbon screen-printed electrodes was developed for the detection of hemagglutinin of influenza A H1N1 virus (H1). Gold nanoflowers were electrodeposited on the electrode to increase conductivity and surface area. The electrochemical signal was amplified by functionalization of the gold nanoflowers with 4-aminothiophenol, which resulted in a 100-fold decrease of the charge transfer resistance due to a tunneling effect. Subsequently, monoclonal antibodies against H1 were immobilized on the surface via covalent amide bond formation, followed by blocking with bovine serum albumin to minimize nonspecific hydrophobic binding. The electrodes were characterized by cyclic voltammetry and electrochemical impedance spectroscopy experiments in the presence of [Fe(CN)<sub>6</sub>]<sup>3-/4-</sup>. Differential pulse voltammetry was used to measure the change in current across the electrode as a function of H1 concentration. This was performed on a series of samples of artificial saliva containing H1 protein in a clinically relevant concentration range. In these experiments, the biosensor showed a limit of detection of 19 pg/mL. Finally, the biosensor platform was coupled to an automated microfluidics system, and no significant decrease of the electrochemical signal was observed.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"540-550"},"PeriodicalIF":2.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12018907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electron beam-based direct writing of nanostructures using a palladium β-ketoesterate complex. 利用钯β-酮酯配合物的电子束直接写入纳米结构。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-15 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.41
Chinmai Sai Jureddy, Krzysztof Maćkosz, Aleksandra Butrymowicz-Kubiak, Iwona B Szymańska, Patrik Hoffmann, Ivo Utke
{"title":"Electron beam-based direct writing of nanostructures using a palladium β-ketoesterate complex.","authors":"Chinmai Sai Jureddy, Krzysztof Maćkosz, Aleksandra Butrymowicz-Kubiak, Iwona B Szymańska, Patrik Hoffmann, Ivo Utke","doi":"10.3762/bjnano.16.41","DOIUrl":"https://doi.org/10.3762/bjnano.16.41","url":null,"abstract":"<p><p>Gas-assisted focused electron beam-induced deposition (FEBID) as a direct, minimally invasive 3D nanopatterning tool offers many advantages in making nanostructures with complex shapes and novel compositions for evolving nanotechnological applications. In this work, structures were nanoprinted using a fluorine-free β-ketoesterate complex, bis(<i>tert</i>-butylacetoacetate)palladium(II), [Pd(tbaoac)<sub>2</sub>]. The internal nanostructure and composition of the deposits were determined, and possible volatile products produced under electron-induced dissociation, explaining the composition, are investigated. A method to eliminate the residual gas contamination during FEBID was implemented. [Pd(tbaoac)<sub>2</sub>] contains large organic ligands and only about 5 atom % palladium in the pristine molecule, yet the obtained palladium content in the deposits amounts to around 30 atom %. This translates to an exceptional removal efficiency of about 90% for the ligand-constituting elements carbon and oxygen through electron-induced dissociation and desorption mechanisms. Comparison with other precursors confirms that the β-ketoesterate family has the highest ligand removal percentage and constitutes thus an interesting model chemistry for further high-metal-content FEBID studies. The possibility of growing nanopillars makes this complex a promising precursor for nanoprinting 3D structures with finely focused electron beams.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"530-539"},"PeriodicalIF":2.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12018897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zeolite materials with Ni and Co: synthesis and catalytic potential in the selective hydrogenation of citral. 含镍、钴的沸石材料的合成及其在柠檬醛选择性加氢中的催化潜力。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-14 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.40
Inocente Rodríguez-Iznaga, Yailen Costa Marrero, Tania Farias Piñeira, Céline Fontaine, Lexane Paget, Beatriz Concepción Rosabal, Arbelio Penton Madrigal, Vitalii Petranovskii, Gwendoline Lafaye
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