Beilstein Journal of Nanotechnology最新文献

New design of operational MEMS bridges for measurements of properties of FEBID-based nanostructures. 用于测量基于 FEBID 的纳米结构特性的新型可操作 MEMS 桥。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.103

Bartosz Pruchnik, Krzysztof Kwoka, Ewelina Gacka, Dominik Badura, Piotr Kunicki, Andrzej Sierakowski, Paweł Janus, Tomasz Piasecki, Teodor Gotszalk

{"title":"New design of operational MEMS bridges for measurements of properties of FEBID-based nanostructures.","authors":"Bartosz Pruchnik, Krzysztof Kwoka, Ewelina Gacka, Dominik Badura, Piotr Kunicki, Andrzej Sierakowski, Paweł Janus, Tomasz Piasecki, Teodor Gotszalk","doi":"10.3762/bjnano.15.103","DOIUrl":"10.3762/bjnano.15.103","url":null,"abstract":"Focused electron beam-induced deposition (FEBID) is a novel technique for the development of multimaterial nanostructures. More importantly, it is applicable to the fabrication of free-standing nanostructures. Experimenting at the nanoscale requires instruments with sufficient resolution and sensitivity to measure various properties of nanostructures. Such measurements (regardless of the nature of the quantities being measured) are particularly problematic in the case of free-standing nanostructures, whose properties must be separated from the measurement system to avoid possible interference. In this paper, we propose novel devices, namely operational micro-electromechanical system (opMEMS) bridges. These are 3D substrates with nanometer-scale actuation capability and equipped with electrical contacts characterised by leakage resistances above 100 GΩ, which provide a platform for comprehensive measurements of properties (i.e., resistance) of free-standing FEBID structures. We also present a use case scenario in which an opMEMS bridge is used to measure the resistance of a free-standing FEBID nanostructure.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional morphology of cleaning devices in the damselfly Ischnura elegans (Odonata, Coenagrionidae). 豆娘 Ischnura elegans（蜻蜓目，鞘翅目）清洁装置的功能形态。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-16 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.102

Silvana Piersanti, Gianandrea Salerno, Wencke Krings, Stanislav Gorb, Manuela Rebora

{"title":"Functional morphology of cleaning devices in the damselfly Ischnura elegans (Odonata, Coenagrionidae).","authors":"Silvana Piersanti, Gianandrea Salerno, Wencke Krings, Stanislav Gorb, Manuela Rebora","doi":"10.3762/bjnano.15.102","DOIUrl":"https://doi.org/10.3762/bjnano.15.102","url":null,"abstract":"Among the different micro- and nanostructures located on cuticular surfaces, grooming devices represent fundamental tools for insect survival. The present study describes the grooming microstructures of the damselfly Ischnura elegans (Odonata, Coenagrionidae) at the adult stage. These structures, situated on the foreleg tibiae, were observed using scanning electron microscopy, and the presence and distribution of resilin, an elastomeric protein that enhances cuticle flexibility, were analyzed using confocal laser scanning microscopy. Eye and antennal grooming behavior were analyzed to evaluate the particle removal efficiency in intact insects and in insects with ablated grooming devices. The grooming devices are constituted of long setae from which a concave cuticular lamina develops towards the medial side of the leg. Each seta shows a material gradient of resilin from its basal to the distal portion and from the seta to the cuticular lamina. The removal of the grooming devices induces a strong increase in the contaminated areas on the eyes after grooming. Further studies on insect grooming can provide valuable data on the functional morphology of insect micro- and nanostructures and can represent a starting point to develop advanced biomimetic cleaning tools.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of a tantalum interlayer in enhancing the properties of Fe₃O₄ thin films. 钽中间层在增强 Fe3O4 薄膜性能方面的作用。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-14 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.101

Hai Dang Ngo, Vo Doan Thanh Truong, Van Qui Le, Hoai Phuong Pham, Thi Kim Hang Pham

{"title":"The role of a tantalum interlayer in enhancing the properties of Fe3O4 thin films.","authors":"Hai Dang Ngo, Vo Doan Thanh Truong, Van Qui Le, Hoai Phuong Pham, Thi Kim Hang Pham","doi":"10.3762/bjnano.15.101","DOIUrl":"https://doi.org/10.3762/bjnano.15.101","url":null,"abstract":"High spin polarization and low resistivity of Fe3O4 at room temperature have been an appealing topic in spintronics with various promising applications. High-quality Fe3O4 thin films are a must to achieve the goals. In this report, Fe3O4 films on different substrates (SiO2/Si(100), MgO(100), and MgO/Ta/SiO2/Si(100)) were fabricated at room temperature with radio-frequency (RF) sputtering and annealed at 450 °C for 2 h. The morphological, structural, and magnetic properties of the deposited samples were characterized with atomic force microscopy, X-ray diffractometry, and vibrating sample magnetometry. The polycrystalline Fe3O4 film grown on MgO/Ta/SiO2/Si(100) presented very interesting morphology and structure characteristics. More importantly, changes in grain size and structure due to the effect of the MgO/Ta buffering layers have a strong impact on saturation magnetization and coercivity of Fe3O4 thin films compared to cases of no or just a single buffering layer.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-functionalized architecture enables stable and tumor cell-specific SiO₂NPs in complex biological fluids. 双重功能化结构可使 SiO2NPs 在复杂的生物液体中保持稳定并具有肿瘤细胞特异性。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.100

Iris Renata Sousa Ribeiro, Raquel Frenedoso da Silva, Romênia Ramos Domingues, Adriana Franco Paes Leme, Mateus Borba Cardoso

{"title":"Dual-functionalized architecture enables stable and tumor cell-specific SiO2NPs in complex biological fluids.","authors":"Iris Renata Sousa Ribeiro, Raquel Frenedoso da Silva, Romênia Ramos Domingues, Adriana Franco Paes Leme, Mateus Borba Cardoso","doi":"10.3762/bjnano.15.100","DOIUrl":"https://doi.org/10.3762/bjnano.15.100","url":null,"abstract":"Most commercial anticancer nanomedicines are administered intravenously. This route is fast and precise as the drug enters directly into the systemic circulation, without undergoing absorption processes. When nanoparticles come into direct contact with the blood, however, they interact with physiological components that can induce colloidal destabilization and/or changes in their original biochemical identity, compromising their ability to selectively accumulate at target sites. In this way, these systems usually lack active targeting, offering limited therapeutic effectiveness. In the literature, there is a paucity of in-depth studies in complex environments to evaluate nanoparticle stability, protein corona formation, hemolytic activity, and targeting capabilities. To address this issue, fluorescent silica nanoparticles (SiO2NPs) are here functionalized with zwitterionic (kinetic stabilizer) and folate groups (targeting agent) to provide selective interaction with tumor cell lines in biological media. The stability of these dually functionalized SiO2NPs is preserved in unprocessed human plasma while yielding a decrease in the number of adsorbed proteins. Experiments in murine blood further proved that these nanoparticles are not hemolytic. Remarkably, the functionalized SiO2NPs are more internalized by tumor cells than their healthy counterparts. Investigations of this nature play a crucial role in garnering results with greater reliability, allowing the development of nanoparticle-based pharmaceutical drugs that exhibit heightened efficacy and reduced toxicity for medical purposes.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142457052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced catalytic reduction through in situ synthesized gold nanoparticles embedded in glucosamine/alginate nanocomposites. 通过嵌入氨基葡萄糖/精氨酸纳米复合材料的原位合成金纳米粒子增强催化还原。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-04 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.99

Chi-Hien Dang, Le-Kim-Thuy Nguyen, Minh-Trong Tran, Van-Dung Le, Nguyen Minh Ty, T Ngoc Han Pham, Hieu Vu-Quang, Tran Thi Kim Chi, Tran Thi Huong Giang, Nguyen Thi Thanh Tu, Thanh-Danh Nguyen

引用次数: 0

Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles. 利用超小型纳米粒子实现癌症纳米药物的主动靶向。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.98

André F Lima, Giselle Z Justo, Alioscka A Sousa

引用次数: 0

A low-kiloelectronvolt focused ion beam strategy for processing low-thermal-conductance materials with nanoampere currents. 用纳安培电流加工低热导材料的低千伏聚焦离子束策略。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-09-27 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.97

Annalena Wolff, Nico Klingner, William Thompson, Yinghong Zhou, Jinying Lin, Yin Xiao

{"title":"A low-kiloelectronvolt focused ion beam strategy for processing low-thermal-conductance materials with nanoampere currents.","authors":"Annalena Wolff, Nico Klingner, William Thompson, Yinghong Zhou, Jinying Lin, Yin Xiao","doi":"10.3762/bjnano.15.97","DOIUrl":"10.3762/bjnano.15.97","url":null,"abstract":"Ion beam-induced heat damage in thermally low conductive specimens such as biological samples is gaining increased interest within the scientific community. This is partly due to the increased use of FIB-SEMs in biology as well as the development of complex materials, such as polymers, which need to be analyzed. The work presented here looks at the physics behind the ion beam-sample interactions and the effect of the incident ion energy (set by the acceleration voltage) on inducing increases in sample temperature and potential heat damage in thermally low conductive materials such as polymers and biological samples. The ion beam-induced heat for different ion beam currents at low acceleration voltages is calculated using Fourier's law of heat transfer, finite element simulations, and numerical modelling results and compared to experiments. The results indicate that with lower accelerator voltages, higher ion beam currents in the nanoampere range can be used to pattern or image soft material and non-resin-embedded biological samples with increased milling speed but reduced heat damage.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11443649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142360969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers. 负载多柔比星的双刺激响应智能纳米聚合物的合成、表征和抗癌效果。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-09-26 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.96

Ömür Acet, Pavel Kirsanov, Burcu Önal Acet, Inessa Halets-Bui, Dzmitry Shcharbin, Şeyda Ceylan Cömert, Mehmet Odabaşı

{"title":"Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers.","authors":"Ömür Acet, Pavel Kirsanov, Burcu Önal Acet, Inessa Halets-Bui, Dzmitry Shcharbin, Şeyda Ceylan Cömert, Mehmet Odabaşı","doi":"10.3762/bjnano.15.96","DOIUrl":"10.3762/bjnano.15.96","url":null,"abstract":"Nanopolymers represent a significant group of delivery vehicles for hydrophobic drugs. In particular, dual stimuli-responsive smart polymer nanomaterials might be extremely useful for drug delivery and release. We analyzed the possibility to include the known antitumor drug doxorubicin (DOX), which has antimitotic and antiproliferative effects, in a nanopolymer complex. Thus, doxorubicin-loaded temperature- and pH-sensitive smart nanopolymers (DOX-SNPs) were produced. Characterizations of the synthesized nanostructures were carried out including zeta potential measurements, Fourier-transform infrared spectroscopy, and scanning electron microscopy. The loading capacity of the nanopolymers for DOX was investigated, and encapsulation and release studies were carried out. In a final step, the cytotoxicity of the DOX-nanopolymer complexes against the HeLa cancer cell line at different concentrations and incubation times was studied. The DOX release depended on temperature and pH value of the release medium, with the highest release at pH 6.0 and 41 °C. This effect was similar to that observed for the commercial liposomal formulation of doxorubicin Doxil. The obtained results demonstrated that smart nanopolymers can be efficiently used to create new types of doxorubicin-based drugs.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11443663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142360970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AI-assisted models to predict chemotherapy drugs modified with C₆₀ fullerene derivatives. 用人工智能辅助模型预测用 C60 富勒烯衍生物修饰的化疗药物。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-09-19 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.95

Jonathan-Siu-Loong Robles-Hernández, Dora Iliana Medina, Katerin Aguirre-Hurtado, Marlene Bosquez, Roberto Salcedo, Alan Miralrio

{"title":"AI-assisted models to predict chemotherapy drugs modified with C60 fullerene derivatives.","authors":"Jonathan-Siu-Loong Robles-Hernández, Dora Iliana Medina, Katerin Aguirre-Hurtado, Marlene Bosquez, Roberto Salcedo, Alan Miralrio","doi":"10.3762/bjnano.15.95","DOIUrl":"https://doi.org/10.3762/bjnano.15.95","url":null,"abstract":"Employing quantitative structure-activity relationship (QSAR)/ quantitative structure-property relationship (QSPR) models, this study explores the application of fullerene derivatives as nanocarriers for breast cancer chemotherapy drugs. Isolated drugs and two drug-fullerene complexes (i.e., drug-pristine C60 fullerene and drug-carboxyfullerene C60-COOH) were investigated with the protein CXCR7 as the molecular docking target. The research involved over 30 drugs and employed Pearson's hard-soft acid-base theory and common QSAR/QSPR descriptors to build predictive models for the docking scores. Energetic descriptors were computed using quantum chemistry at the density functional-based tight binding DFTB3 level. The results indicate that drug-fullerene complexes interact more with CXCR7 than isolated drugs. Specific binding sites were identified, with varying locations for each drug complex. Predictive models, developed using multiple linear regression and IBM Watson artificial intelligence (AI), achieved mean absolute percentage errors below 12%, driven by AI-identified key variables. The predictive models included mainly quantitative descriptors collected from datasets as well as computed ones. In addition, a water-soluble fullerene was used to compare results obtained by DFTB3 with a conventional density functional theory approach. These findings promise to enhance breast cancer chemotherapy by leveraging fullerene-based drug nanocarriers.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11420546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantum-to-classical modeling of monolayer Ge₂Se₂ and its application in photovoltaic devices. 单层 Ge2Se2 的量子到经典模型及其在光伏设备中的应用。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-09-11 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.94

Anup Shrivastava, Shivani Saini, Dolly Kumari, Sanjai Singh, Jost Adam

{"title":"Quantum-to-classical modeling of monolayer Ge2Se2 and its application in photovoltaic devices.","authors":"Anup Shrivastava, Shivani Saini, Dolly Kumari, Sanjai Singh, Jost Adam","doi":"10.3762/bjnano.15.94","DOIUrl":"https://doi.org/10.3762/bjnano.15.94","url":null,"abstract":"Since the discovery of graphene in 2004, the unique properties of two-dimensional materials have sparked intense research interest regarding their use as alternative materials in various photonic applications. Transition metal dichalcogenide monolayers have been proposed as transport layers in photovoltaic cells, but the promising characteristics of group IV-VI dichalcogenides are yet to be thoroughly investigated. This manuscript reports on monolayer Ge2Se2 (a group IV-VI dichalcogenide), its optoelectronic behavior, and its potential application in photovoltaics. When employed as a hole transport layer, the material fosters an astonishing device performance. We use ab initio modeling for the material prediction, while classical drift-diffusion drives the device simulations. Hybrid functionals calculate electronic and optical properties to maintain high accuracy. The structural stability has been verified using phonon spectra. The E-k dispersion reveals the investigated material's key electronic properties. The calculations reveal a direct bandgap of 1.12 eV for monolayer Ge2Se2. We further extract critical optical parameters using the Kubo-Greenwood formalism and Kramers-Kronig relations. A significantly large absorption coefficient and a high dielectric constant inspired the design of a monolayer Ge2Se2-based solar cell, exhibiting a high open circuit voltage of V oc = 1.11 V, a fill factor of 87.66%, and more than 28% power conversion efficiency at room temperature. Our findings advocate monolayer Ge2Se2 for various optoelectronic devices, including next-generation solar cells. The hybrid quantum-to-macroscopic methodology presented here applies to broader classes of 2D and 3D materials and structures, showing a path to the computational design of future photovoltaic materials.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11406054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0