Beilstein Journal of Nanotechnology最新文献_第7页

Interaction of graphene oxide with tannic acid: computational modeling and toxicity mitigation in C. elegans. 氧化石墨烯与单宁酸的相互作用：计算建模和减轻对优雅小鼠的毒性。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-30 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.105

Romana Petry, James M de Almeida, Francine Côa, Felipe Crasto de Lima, Diego Stéfani T Martinez, Adalberto Fazzio

{"title":"Interaction of graphene oxide with tannic acid: computational modeling and toxicity mitigation in C. elegans.","authors":"Romana Petry, James M de Almeida, Francine Côa, Felipe Crasto de Lima, Diego Stéfani T Martinez, Adalberto Fazzio","doi":"10.3762/bjnano.15.105","DOIUrl":"10.3762/bjnano.15.105","url":null,"abstract":"Graphene oxide (GO) undergoes multiple transformations when introduced to biological and environmental media. GO surface favors the adsorption of biomolecules through different types of interaction mechanisms, modulating the biological effects of the material. In this study, we investigated the interaction of GO with tannic acid (TA) and its consequences for GO toxicity. We focused on understanding how TA interacts with GO, its impact on the material surface chemistry, colloidal stability, as well as, toxicity and biodistribution using the Caenorhabditis elegans model. Employing computational modeling, including reactive classical molecular dynamics and ab initio calculations, we reveal that TA preferentially binds to the most reactive sites on GO surfaces via the oxygen-containing groups or the carbon matrix; van der Waals interaction forces dominate the binding energy. TA exhibits a dose-dependent mitigating effect on the toxicity of GO, which can be attributed not only to the surface interactions between the molecule and the material but also to the inherent biological properties of TA in C. elegans. Our findings contribute to a deeper understanding of GO's environmental behavior and toxicity and highlight the potential of tannic acid for the synthesis and surface functionalization of graphene-based nanomaterials, offering insights into safer nanotechnology development.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1297-1311"},"PeriodicalIF":2.6,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11533115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mn-doped ZnO nanopowders prepared by sol-gel and microwave-assisted sol-gel methods and their photocatalytic properties. 溶胶-凝胶法和微波辅助溶胶-凝胶法制备的掺锰氧化锌纳米粉体及其光催化性能。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-28 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.104

Cristina Maria Vlăduț, Crina Anastasescu, Silviu Preda, Oana Catalina Mocioiu, Simona Petrescu, Jeanina Pandele-Cusu, Dana Culita, Veronica Bratan, Ioan Balint, Maria Zaharescu

{"title":"Mn-doped ZnO nanopowders prepared by sol-gel and microwave-assisted sol-gel methods and their photocatalytic properties.","authors":"Cristina Maria Vlăduț, Crina Anastasescu, Silviu Preda, Oana Catalina Mocioiu, Simona Petrescu, Jeanina Pandele-Cusu, Dana Culita, Veronica Bratan, Ioan Balint, Maria Zaharescu","doi":"10.3762/bjnano.15.104","DOIUrl":"10.3762/bjnano.15.104","url":null,"abstract":"Although the microwave-assisted sol-gel method is quite frequently used for the preparation of oxide nanostructures, the synergism of the reaction pathways is not fully explained. However, state-of-the-art theoretical and practical results of high novelty can be achieved by continuously evaluating the as-synthesized materials. The present paper presents a comparative study of Mn-doped ZnO nanopowders prepared by both sol-gel and microwave-assisted sol-gel methods. The structural, morphological, and optical properties of the as-obtained powders were established and correlated with their newly proved functionality, namely, the ability to photogenerate distinct reactive oxygen species (·OH or O2 -) and to act as photoactive materials in aqueous media. The solar light-induced mineralization of oxalic acid by Mn-doped ZnO materials was clearly observed while similar amounts of generated CO2 were measured for both catalysts. These inexpensive semiconductor materials, which proved to be light-responsive, can be further used for developing water depollution technologies based on solar light energy.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1283-1296"},"PeriodicalIF":2.6,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11535566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New design of operational MEMS bridges for measurements of properties of FEBID-based nanostructures. 用于测量基于 FEBID 的纳米结构特性的新型可操作 MEMS 桥。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.103

Bartosz Pruchnik, Krzysztof Kwoka, Ewelina Gacka, Dominik Badura, Piotr Kunicki, Andrzej Sierakowski, Paweł Janus, Tomasz Piasecki, Teodor Gotszalk

{"title":"New design of operational MEMS bridges for measurements of properties of FEBID-based nanostructures.","authors":"Bartosz Pruchnik, Krzysztof Kwoka, Ewelina Gacka, Dominik Badura, Piotr Kunicki, Andrzej Sierakowski, Paweł Janus, Tomasz Piasecki, Teodor Gotszalk","doi":"10.3762/bjnano.15.103","DOIUrl":"10.3762/bjnano.15.103","url":null,"abstract":"Focused electron beam-induced deposition (FEBID) is a novel technique for the development of multimaterial nanostructures. More importantly, it is applicable to the fabrication of free-standing nanostructures. Experimenting at the nanoscale requires instruments with sufficient resolution and sensitivity to measure various properties of nanostructures. Such measurements (regardless of the nature of the quantities being measured) are particularly problematic in the case of free-standing nanostructures, whose properties must be separated from the measurement system to avoid possible interference. In this paper, we propose novel devices, namely operational micro-electromechanical system (opMEMS) bridges. These are 3D substrates with nanometer-scale actuation capability and equipped with electrical contacts characterised by leakage resistances above 100 GΩ, which provide a platform for comprehensive measurements of properties (i.e., resistance) of free-standing FEBID structures. We also present a use case scenario in which an opMEMS bridge is used to measure the resistance of a free-standing FEBID nanostructure.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1273-1282"},"PeriodicalIF":2.6,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional morphology of cleaning devices in the damselfly Ischnura elegans (Odonata, Coenagrionidae). 豆娘 Ischnura elegans（蜻蜓目，鞘翅目）清洁装置的功能形态。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-16 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.102

Silvana Piersanti, Gianandrea Salerno, Wencke Krings, Stanislav Gorb, Manuela Rebora

{"title":"Functional morphology of cleaning devices in the damselfly Ischnura elegans (Odonata, Coenagrionidae).","authors":"Silvana Piersanti, Gianandrea Salerno, Wencke Krings, Stanislav Gorb, Manuela Rebora","doi":"10.3762/bjnano.15.102","DOIUrl":"https://doi.org/10.3762/bjnano.15.102","url":null,"abstract":"Among the different micro- and nanostructures located on cuticular surfaces, grooming devices represent fundamental tools for insect survival. The present study describes the grooming microstructures of the damselfly Ischnura elegans (Odonata, Coenagrionidae) at the adult stage. These structures, situated on the foreleg tibiae, were observed using scanning electron microscopy, and the presence and distribution of resilin, an elastomeric protein that enhances cuticle flexibility, were analyzed using confocal laser scanning microscopy. Eye and antennal grooming behavior were analyzed to evaluate the particle removal efficiency in intact insects and in insects with ablated grooming devices. The grooming devices are constituted of long setae from which a concave cuticular lamina develops towards the medial side of the leg. Each seta shows a material gradient of resilin from its basal to the distal portion and from the seta to the cuticular lamina. The removal of the grooming devices induces a strong increase in the contaminated areas on the eyes after grooming. Further studies on insect grooming can provide valuable data on the functional morphology of insect micro- and nanostructures and can represent a starting point to develop advanced biomimetic cleaning tools.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1260-1272"},"PeriodicalIF":2.6,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of a tantalum interlayer in enhancing the properties of Fe₃O₄ thin films. 钽中间层在增强 Fe3O4 薄膜性能方面的作用。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-14 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.101

Hai Dang Ngo, Vo Doan Thanh Truong, Van Qui Le, Hoai Phuong Pham, Thi Kim Hang Pham

{"title":"The role of a tantalum interlayer in enhancing the properties of Fe3O4 thin films.","authors":"Hai Dang Ngo, Vo Doan Thanh Truong, Van Qui Le, Hoai Phuong Pham, Thi Kim Hang Pham","doi":"10.3762/bjnano.15.101","DOIUrl":"https://doi.org/10.3762/bjnano.15.101","url":null,"abstract":"High spin polarization and low resistivity of Fe3O4 at room temperature have been an appealing topic in spintronics with various promising applications. High-quality Fe3O4 thin films are a must to achieve the goals. In this report, Fe3O4 films on different substrates (SiO2/Si(100), MgO(100), and MgO/Ta/SiO2/Si(100)) were fabricated at room temperature with radio-frequency (RF) sputtering and annealed at 450 °C for 2 h. The morphological, structural, and magnetic properties of the deposited samples were characterized with atomic force microscopy, X-ray diffractometry, and vibrating sample magnetometry. The polycrystalline Fe3O4 film grown on MgO/Ta/SiO2/Si(100) presented very interesting morphology and structure characteristics. More importantly, changes in grain size and structure due to the effect of the MgO/Ta buffering layers have a strong impact on saturation magnetization and coercivity of Fe3O4 thin films compared to cases of no or just a single buffering layer.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1253-1259"},"PeriodicalIF":2.6,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-functionalized architecture enables stable and tumor cell-specific SiO₂NPs in complex biological fluids. 双重功能化结构可使 SiO2NPs 在复杂的生物液体中保持稳定并具有肿瘤细胞特异性。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.100

Iris Renata Sousa Ribeiro, Raquel Frenedoso da Silva, Romênia Ramos Domingues, Adriana Franco Paes Leme, Mateus Borba Cardoso

{"title":"Dual-functionalized architecture enables stable and tumor cell-specific SiO2NPs in complex biological fluids.","authors":"Iris Renata Sousa Ribeiro, Raquel Frenedoso da Silva, Romênia Ramos Domingues, Adriana Franco Paes Leme, Mateus Borba Cardoso","doi":"10.3762/bjnano.15.100","DOIUrl":"https://doi.org/10.3762/bjnano.15.100","url":null,"abstract":"Most commercial anticancer nanomedicines are administered intravenously. This route is fast and precise as the drug enters directly into the systemic circulation, without undergoing absorption processes. When nanoparticles come into direct contact with the blood, however, they interact with physiological components that can induce colloidal destabilization and/or changes in their original biochemical identity, compromising their ability to selectively accumulate at target sites. In this way, these systems usually lack active targeting, offering limited therapeutic effectiveness. In the literature, there is a paucity of in-depth studies in complex environments to evaluate nanoparticle stability, protein corona formation, hemolytic activity, and targeting capabilities. To address this issue, fluorescent silica nanoparticles (SiO2NPs) are here functionalized with zwitterionic (kinetic stabilizer) and folate groups (targeting agent) to provide selective interaction with tumor cell lines in biological media. The stability of these dually functionalized SiO2NPs is preserved in unprocessed human plasma while yielding a decrease in the number of adsorbed proteins. Experiments in murine blood further proved that these nanoparticles are not hemolytic. Remarkably, the functionalized SiO2NPs are more internalized by tumor cells than their healthy counterparts. Investigations of this nature play a crucial role in garnering results with greater reliability, allowing the development of nanoparticle-based pharmaceutical drugs that exhibit heightened efficacy and reduced toxicity for medical purposes.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1238-1252"},"PeriodicalIF":2.6,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142457052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced catalytic reduction through in situ synthesized gold nanoparticles embedded in glucosamine/alginate nanocomposites. 通过嵌入氨基葡萄糖/精氨酸纳米复合材料的原位合成金纳米粒子增强催化还原。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-10-04 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.99

Chi-Hien Dang, Le-Kim-Thuy Nguyen, Minh-Trong Tran, Van-Dung Le, Nguyen Minh Ty, T Ngoc Han Pham, Hieu Vu-Quang, Tran Thi Kim Chi, Tran Thi Huong Giang, Nguyen Thi Thanh Tu, Thanh-Danh Nguyen

引用次数: 0

Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles. 利用超小型纳米粒子实现癌症纳米药物的主动靶向。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.98

André F Lima, Giselle Z Justo, Alioscka A Sousa

引用次数: 0

A low-kiloelectronvolt focused ion beam strategy for processing low-thermal-conductance materials with nanoampere currents. 用纳安培电流加工低热导材料的低千伏聚焦离子束策略。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-09-27 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.97

Annalena Wolff, Nico Klingner, William Thompson, Yinghong Zhou, Jinying Lin, Yin Xiao

{"title":"A low-kiloelectronvolt focused ion beam strategy for processing low-thermal-conductance materials with nanoampere currents.","authors":"Annalena Wolff, Nico Klingner, William Thompson, Yinghong Zhou, Jinying Lin, Yin Xiao","doi":"10.3762/bjnano.15.97","DOIUrl":"10.3762/bjnano.15.97","url":null,"abstract":"Ion beam-induced heat damage in thermally low conductive specimens such as biological samples is gaining increased interest within the scientific community. This is partly due to the increased use of FIB-SEMs in biology as well as the development of complex materials, such as polymers, which need to be analyzed. The work presented here looks at the physics behind the ion beam-sample interactions and the effect of the incident ion energy (set by the acceleration voltage) on inducing increases in sample temperature and potential heat damage in thermally low conductive materials such as polymers and biological samples. The ion beam-induced heat for different ion beam currents at low acceleration voltages is calculated using Fourier's law of heat transfer, finite element simulations, and numerical modelling results and compared to experiments. The results indicate that with lower accelerator voltages, higher ion beam currents in the nanoampere range can be used to pattern or image soft material and non-resin-embedded biological samples with increased milling speed but reduced heat damage.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1197-1207"},"PeriodicalIF":2.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11443649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142360969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers. 负载多柔比星的双刺激响应智能纳米聚合物的合成、表征和抗癌效果。

IF 2.6 4区材料科学

Beilstein Journal of Nanotechnology Pub Date : 2024-09-26 eCollection Date: 2024-01-01 DOI: 10.3762/bjnano.15.96

Ömür Acet, Pavel Kirsanov, Burcu Önal Acet, Inessa Halets-Bui, Dzmitry Shcharbin, Şeyda Ceylan Cömert, Mehmet Odabaşı

{"title":"Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers.","authors":"Ömür Acet, Pavel Kirsanov, Burcu Önal Acet, Inessa Halets-Bui, Dzmitry Shcharbin, Şeyda Ceylan Cömert, Mehmet Odabaşı","doi":"10.3762/bjnano.15.96","DOIUrl":"10.3762/bjnano.15.96","url":null,"abstract":"Nanopolymers represent a significant group of delivery vehicles for hydrophobic drugs. In particular, dual stimuli-responsive smart polymer nanomaterials might be extremely useful for drug delivery and release. We analyzed the possibility to include the known antitumor drug doxorubicin (DOX), which has antimitotic and antiproliferative effects, in a nanopolymer complex. Thus, doxorubicin-loaded temperature- and pH-sensitive smart nanopolymers (DOX-SNPs) were produced. Characterizations of the synthesized nanostructures were carried out including zeta potential measurements, Fourier-transform infrared spectroscopy, and scanning electron microscopy. The loading capacity of the nanopolymers for DOX was investigated, and encapsulation and release studies were carried out. In a final step, the cytotoxicity of the DOX-nanopolymer complexes against the HeLa cancer cell line at different concentrations and incubation times was studied. The DOX release depended on temperature and pH value of the release medium, with the highest release at pH 6.0 and 41 °C. This effect was similar to that observed for the commercial liposomal formulation of doxorubicin Doxil. The obtained results demonstrated that smart nanopolymers can be efficiently used to create new types of doxorubicin-based drugs.","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"15 ","pages":"1189-1196"},"PeriodicalIF":2.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11443663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142360970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0