Artificial Cells, Nanomedicine, and Biotechnology最新文献_第4页

Artificial intelligence-driven design of next-generation nanomedicine: transforming precision healthcare. 人工智能驱动的新一代纳米医学设计：改变精准医疗。

IF 5.6 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2026-12-01 Epub Date: 2026-08-13 DOI: 10.1080/21691401.2026.2715934

R D K Misra

引用次数: 0

Network pharmacology, and molecular docking studies for two flavonoid compounds isolated from Dodonaea viscosa towards SARS-CoV-2 infection and loaded in lipid nanoparticles. 脂质纳米颗粒负载的粘家蚕分离的两种黄酮类化合物抗SARS-CoV-2感染的网络药理学和分子对接研究。

IF 5.6 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2026-12-01 Epub Date: 2026-09-06 DOI: 10.1080/21691401.2026.2726112

Marzough Aziz Albalawi, Sameera Al-Ghamdi, Mahmoud Fahmi Elsebai, Marwa Anwar Wagdi, Saadiya El-Nahas, Mohammad Y Alfaifi, Banan Al-Shagour, Fatma Alzahraa Mokhtar

{"title":"Network pharmacology, and molecular docking studies for two flavonoid compounds isolated from Dodonaea viscosa towards SARS-CoV-2 infection and loaded in lipid nanoparticles.","authors":"Marzough Aziz Albalawi, Sameera Al-Ghamdi, Mahmoud Fahmi Elsebai, Marwa Anwar Wagdi, Saadiya El-Nahas, Mohammad Y Alfaifi, Banan Al-Shagour, Fatma Alzahraa Mokhtar","doi":"10.1080/21691401.2026.2726112","DOIUrl":"https://doi.org/10.1080/21691401.2026.2726112","url":null,"abstract":"Dodonaea viscosa is one of the widely distributed ornamental plants. It is rich in many phytoconstituents. The present study aims to examine the activity of spanlastics formulations loaded with compounds isolated from Dodonaea viscosa leaves extract. The isolated compounds were identified and loaded into nanovesicles. The anti-SARS-CoV-2 activity of selected drug-loaded spanlastics was evaluated using MTT assay and the underlying mechanism of action was determined. The formulations showed high encapsulation efficiency with vesicle diameters in the nanometre range. The vesicles were spherical and exhibited large negative values of zeta potential, indicating good stability. Selected formulations of V and S (V1 and S1) exhibited high antiviral activity against SARS-CoV-2 with IC50 of 4.483 and 9.795 µg/ml for V1 and S1, respectively, through inhibition of virus adsorption for V1 and virucidal activity by 55.7 % for S1. The network pharmacology defined the EGFR as the top annotated gene with 7 edges, followed by PIK3CG, VEGFA, and MMP9 genes with 4 edges for each. Molecular docking simulations reveal favourable binding affinities and diverse interactions with critical amino acid residues. In silico ADMET profiling further indicated that both compounds are drug-like, with favourable absorption and core-safety signatures (non-mutagenic, non-carcinogenic, and non-cardiotoxic). Santin and viscosine formulated nanovesicles represent promising formulations with therapeutic potential against SARS-CoV-2.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"54 1","pages":"434-451"},"PeriodicalIF":5.6,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148899998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of anti-psoriatic activity, mechanistic insights, nanoformulation, and GC-MS profiling of Commiphora gileadensis essential oil. 抗银屑病活性的评价，机制的见解，纳米配方，和气相色谱-质谱分析的金缕草精油。

IF 5.6 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2026-12-01 Epub Date: 2026-10-17 DOI: 10.1080/21691401.2026.2742624

Fawaz K Alanazi, Nashwa Hashad, Asmaa A Ahmed, Elsayed K El-Sayed, Nadeem Ahmed, Mohamed I S Abdelhady, Fatma M Abdel Bar, Eman G Haggag

{"title":"Evaluation of anti-psoriatic activity, mechanistic insights, nanoformulation, and GC-MS profiling of Commiphora gileadensis essential oil.","authors":"Fawaz K Alanazi, Nashwa Hashad, Asmaa A Ahmed, Elsayed K El-Sayed, Nadeem Ahmed, Mohamed I S Abdelhady, Fatma M Abdel Bar, Eman G Haggag","doi":"10.1080/21691401.2026.2742624","DOIUrl":"https://doi.org/10.1080/21691401.2026.2742624","url":null,"abstract":"Psoriasis is a chronic inflammatory immune-mediated skin disease with complex pathophysiology, reflecting the need for effective treatment. Commiphora gileadensis (L.) C.Chr. has long been used traditionally for skin disorders; however, its anti-psoriatic potential remains unexplored. This study investigated the GC-MS chemical profile of C. gileadensis hydro-distilled essential oil from its aerial parts, revealing sabinene and viridiflorol as the major compounds. Nanoemulgel formulations of the oil (Eg: 0.25%, 0.5%, and 1% w/w) were evaluated in an imiquimod (IMQ)-induced psoriasis-like model in BALB/c mice. Treatment with Eg significantly decreased the psoriasis area and severity index and spleen index in a dose-dependent manner, with the highest efficacy at 1%. It exhibited antioxidant properties by increasing glutathione and decreasing malondialdehyde, and an anti-inflammatory effect by inhibiting the phosphorylated nuclear factor-κB and inflammatory interleukins IL-17, IL-23, IL-1β, and IL-18. It attenuated tissue pyroptosis and restored cellular autophagy, supported by histopathology and reduced Ki67 expression. These findings highlight nanoemulgel of C. gileadensis essential oil as a potential therapy to alleviate psoriasis.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"54 1","pages":"863-889"},"PeriodicalIF":5.6,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cross-talk between diabetic nephropathy and bone loss: PBMCs-guided discovery of NLRP3-inflammatory signalling. 糖尿病肾病与骨质流失之间的相互作用：pbmcs引导下nlrp3炎症信号的发现。

IF 4.5 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2026-12-01 Epub Date: 2025-12-26 DOI: 10.1080/21691401.2025.2603849

Qiang Zhang, Yue Wang, Xiao Ning Lin, Yong Cheng Xu, Miao Xu, Xuan Lin, Yue Lai, Huan Liu, Jian Lin Shen

{"title":"Cross-talk between diabetic nephropathy and bone loss: PBMCs-guided discovery of NLRP3-inflammatory signalling.","authors":"Qiang Zhang, Yue Wang, Xiao Ning Lin, Yong Cheng Xu, Miao Xu, Xuan Lin, Yue Lai, Huan Liu, Jian Lin Shen","doi":"10.1080/21691401.2025.2603849","DOIUrl":"https://doi.org/10.1080/21691401.2025.2603849","url":null,"abstract":"Diabetic nephropathy (DN), a major driver of end-stage kidney disease, elevates the risk for osteoporosis (OP) and its clinical precursor, low bone mineral density (low BMD), indicating broader systemic effects. While peripheral blood mononuclear cells (PBMCs) participate in both conditions, their common mechanisms remain poorly understood. This study aimed to identify common biomarkers and pathways linking DN to OP/low BMD by analyzing transcriptomic datasets from patients with these conditions. Using weighted gene co-expression network analysis (WGCNA), machine learning, and differential expression validation, we identified NLRP3 as a central hub gene. Functional analyses connected NLRP3 to pro-inflammatory pathways and immune cell activation. Single-cell data showed specific NLRP3 overexpression in DN patient macrophages, which exhibited heightened osteoclast differentiation capability. Protein analysis confirmed elevated NLRP3 levels in DN cases. In conclusion, PBMCs from DN patients with comorbid osteoporosis show upregulated NLRP3 expression and inflammasome activation, which may drive systemic inflammation and bone loss. These results clarify the pathological link between DN and OP/low BMD and highlight NLRP3 as a potential diagnostic marker and therapeutic target.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"54 1","pages":"19-36"},"PeriodicalIF":4.5,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hierarchical laminin-MgCO₃ gradient layers on Sr/ZnO ion-implanted titanium for multifunctional bone regeneration. Sr/ZnO离子植入钛上分层层粘胶蛋白- mgco3梯度层用于多功能骨再生。

IF 5.6 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2026-12-01 Epub Date: 2026-04-27 DOI: 10.1080/21691401.2026.2649072

Rojaleen Lenka, Subhasmita Swain, R D K Misra, Tapash R Rautray

{"title":"Hierarchical laminin-MgCO3 gradient layers on Sr/ZnO ion-implanted titanium for multifunctional bone regeneration.","authors":"Rojaleen Lenka, Subhasmita Swain, R D K Misra, Tapash R Rautray","doi":"10.1080/21691401.2026.2649072","DOIUrl":"10.1080/21691401.2026.2649072","url":null,"abstract":"Given that the bio-inert behaviour of the Ti surface presents a challenge under certain compromised conditions, it is necessary that the surface is tuned to ensure strong osseointegration between the implant and the adjacent bone. The present study is aimed at modifying Ti surface through ion implantation of Sr2+ and Zn2+ to form zinc oxide/strontium doped-Ti surface and incorporate magnesium carbonate (MgCO3, MC) in the coating via a low-temperature high-speed collision (LTHSC) technique. This was subsequently followed by a dip-coating of laminin (Lam) layer. This MC-ZnO/Sr-Lam coated (MC wt% = 10%, 20%, 30%) Ti substrate was subjected to physical and biological characterizations. The 10MC-ZnO/Sr-Lam coating showed the highest adhesion strength (27.1 ± 1.28 MPa) and lowest contact angle (∼38°±1.74), indicating superior coating stability and wettability. Mg2+ release was concentration-dependent, ranging from ∼6.5 to 588.6 ppm, with 20MC-ZnO/Sr-Lam delivering an optimal sustained release adhesion and proliferation, with the 30MC-ZnO/Sr-Lam coating demonstrating highest upregulation of osteogenic markers (RUNX2, COL1 and OCN) relative to Ti. Overall, the 20MC-ZnO/Sr-Lam coating provided the best balance between adhesion strength, controlled ion release, osteogenic enhancement and antibacterial efficacy, highlighting its potential as an optimized surface modification strategy for multifunctional bone implant applications.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"54 1","pages":"36-52"},"PeriodicalIF":5.6,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147760474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lactobacillus acidophilus membrane vesicles demonstrate antimicrobial and antibiofilm activity against Streptococcus mutans - an in vitro and in vivo study. 嗜酸乳杆菌膜囊泡对变形链球菌具有抗菌和抗生物膜活性-一项体外和体内研究。

IF 5.6 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2026-12-01 Epub Date: 2026-04-29 DOI: 10.1080/21691401.2026.2662204

Venkatramanan Mahendrarajan, Nalini Easwaran

{"title":"Lactobacillus acidophilus membrane vesicles demonstrate antimicrobial and antibiofilm activity against Streptococcus mutans - an in vitro and in vivo study.","authors":"Venkatramanan Mahendrarajan, Nalini Easwaran","doi":"10.1080/21691401.2026.2662204","DOIUrl":"10.1080/21691401.2026.2662204","url":null,"abstract":"Despite considerable research and various treatment approaches, dental decay remains a global health challenge. The use of synthetic antimicrobial agents can promote the development of resistance and may lead to adverse side effects. Streptococcus mutans is a key contributor to oral diseases, more so than other oral pathogens. Probiotics, however, play a beneficial role in maintaining oral health. Specifically, Lactobacillus acidophilus in the mouth can hinder harmful bacteria by competing for nutrients. Yet, evidence suggests they may also promote tooth decay. Our research focuses on membrane vesicles (MVs) isolation from L. acidophilus, and in vitro and in vivo antibacterial screening against S. mutans. The isolated MVs were consistent with previously reported vesicle size, zeta potential, and spherical morphology. They exhibit significant antimicrobial properties, prevent biofilm formation, hinder bacterial adhesion and invasion, and reduce the expression of virulence genes brpA, comDE, and spaP against S. mutans. In the in vivo model, they effectively eliminated S. mutans infection, strengthening the significance of our in vitro findings. Further proteomics study reveals the presence of possible antimicrobial peptides revealed by the DBAASP database. This study highlights the potential of MVs as a therapeutic strategy that could offer alternatives to traditional treatments and help tackle antibiotic resistance.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"54 1","pages":"17-35"},"PeriodicalIF":5.6,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147761045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of pathogenic novel intronic splicing variants in the KIDINS220 gene causes motor developmental delay. 检测致病的新的内含子剪接变异在KIDINS220基因导致运动发育迟缓。

IF 5.6 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2026-12-01 Epub Date: 2026-01-11 DOI: 10.1080/21691401.2026.2612914

Lu Bai, Yu Hei, Rujin Tian, Haozheng Zhang, Hongmei Xin, Yanan Yang, Lili Ge, Yuqiang Lv, Xiao Mu, Zhongtao Gai, Guohua Liu, Lifen Gao, Kaihui Zhang

{"title":"Detection of pathogenic novel intronic splicing variants in the KIDINS220 gene causes motor developmental delay.","authors":"Lu Bai, Yu Hei, Rujin Tian, Haozheng Zhang, Hongmei Xin, Yanan Yang, Lili Ge, Yuqiang Lv, Xiao Mu, Zhongtao Gai, Guohua Liu, Lifen Gao, Kaihui Zhang","doi":"10.1080/21691401.2026.2612914","DOIUrl":"10.1080/21691401.2026.2612914","url":null,"abstract":"Pathogenic variants in the KIDINS220 gene can cause SINO syndrome (OMIM #617296), VENARG syndrome (OMIM #619501), or other neurological and metabolic disorders such as obesity and nystagmus. We identified two novel intronic variants in intron 29 of KIDINS220 gene (NM_020738.4), c.4054-2A > G and c.4054-7T > C, in a female patient presenting with motor dysfunction and developmental delay. Brain MRI revealed delayed myelination. To investigate whether these intronic variants cause aberrant splicing and affect protein expression, we sequenced KIDINS220 cDNA from peripheral blood and concurrently performed a minigene splicing assay. The results indicated that KIDINS220 was not expressed in PBMCs. However, the minigene assay demonstrated that the c.4054-2A > G variant causes an in-frame 336-bp deletion in exon 30, resulting in a 112-amino acid deletion in the C-terminal region of KIDINS220 (p.(Ser1352_Ser1463del)). In contrast, the c.4054-7T > C variant did not disrupt normal splicing. Based on the patient's clinical features and functional validation of the genetic variants, our paediatricians established a diagnosis of mild motor dysfunction and developmental delay. Our findings broaden the spectrum of pathogenic variants underlying KIDINS220-related disorders and provide essential information for genetic counselling.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"54 1","pages":"74-84"},"PeriodicalIF":5.6,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective effect of Salvia Miltiorrhiza Injection on myocardial injury in rats with haemorrhagic shock resuscitated by HBOC-CHP01. 丹参注射液对HBOC-CHP01复苏失血性休克大鼠心肌损伤的保护作用。

IF 5.6 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2026-12-01 Epub Date: 2026-02-27 DOI: 10.1080/21691401.2026.2632551

Shasha Hao, Xintong Xie, Shen Li, Honghui Zhang, Hong Wang, Chengmin Yang, Wentao Zhou, Jiaxin Liu

{"title":"Protective effect of Salvia Miltiorrhiza Injection on myocardial injury in rats with haemorrhagic shock resuscitated by HBOC-CHP01.","authors":"Shasha Hao, Xintong Xie, Shen Li, Honghui Zhang, Hong Wang, Chengmin Yang, Wentao Zhou, Jiaxin Liu","doi":"10.1080/21691401.2026.2632551","DOIUrl":"10.1080/21691401.2026.2632551","url":null,"abstract":"This study investigated whether Salvia Miltiorrhiza Injection (SMI) could mitigate acute myocardial injury following resuscitation from severe haemorrhagic shock with the hemoglobin-based oxygen carrier HBOC-CHP01. Network pharmacology was first used to predict SMI's potential mechanisms. In vivo, a 50% severe haemorrhagic shock model was induced in rats, which were then resuscitated with either HBOC-CHP01 alone (n=12) or HBOC-CHP01 plus SMI (8.0 ml/kg, n=12). Subgroups were assessed for 72-hour survival, blood parameters, and myocardial tissue injury at 24 hours post-resuscitation. Network pharmacology identified 189 potential targets, with AKT1, CASP3, and HIF-1α among the core candidates. In vivo, while 72-hour survival was unchanged, SMI significantly reduced plasma cardiac injury markers (AST, LDH, CK, cTnI) at 24 hours post-resuscitation compared to HBOC-CHP01 alone. Histological analysis revealed markedly reduced myocardial inflammation and apoptosis in the SMI-treated group. This cardioprotection was associated with significant upregulation of myocardial Nrf2 and HO-1, alongside reduced reactive oxygen species and myeloperoxidase levels. In conclusion, SMI reduces myocardial injury after HBOC-CHP01 resuscitation in haemorrhagic shock rats, primarily by activating the Nrf2/HO-1 antioxidant pathway, suggesting its potential as an adjunctive therapy to improve the safety of hemoglobin-based oxygen carriers.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"54 1","pages":"193-208"},"PeriodicalIF":5.6,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147301441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immune regulatory mechanisms and potential microbiota-associated targets in Kawasaki disease: an integrative multi-omics and network pharmacology study. 川崎病的免疫调节机制和潜在的微生物相关靶点：一项综合多组学和网络药理学研究

IF 5.6 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2026-12-01 Epub Date: 2026-07-09 DOI: 10.1080/21691401.2026.2700919

Zhaojun Mei, Xiaoqin Xiong

{"title":"Immune regulatory mechanisms and potential microbiota-associated targets in Kawasaki disease: an integrative multi-omics and network pharmacology study.","authors":"Zhaojun Mei, Xiaoqin Xiong","doi":"10.1080/21691401.2026.2700919","DOIUrl":"https://doi.org/10.1080/21691401.2026.2700919","url":null,"abstract":"Kawasaki disease (KD) is a systemic vasculitis in children primarily affecting the coronary arteries, and studies suggest that the gut microbiota may be involved in KD pathogenesis, inflammatory responses, and immune regulation. This study employed an integrative multi-omics strategy to systematically investigate gut microbiota-metabolite interactions in KD. Key molecular targets were identified using network-based analyses and machine learning models, with Mendelian randomization providing causal validation. Single-cell transcriptomics and molecular docking further elucidated immune cell interactions and metabolite-protein binding, highlighting critical regulatory pathways. We identified SELP as a core molecular target in KD, predominantly expressed in platelets and involved in immune and inflammatory responses. Gut microbiota-derived metabolites, including palmitoylethanolamide, pantothenic acid, and 1-O-caffeoylglycerol, may regulate immune cell interactions via the RESISTIN signalling pathway. Altered abundances of microbial taxa such as Bacteroides, Parabacteroides, and Bifidobacterium suggest their potential role in inflammation modulation. Activation of IL-17, TNF, MAPK, and PI3K-Akt pathways further contributes to disease progression, highlighting the microbiota-metabolite-SELP axis as a potential therapeutic target in KD. These findings lay the groundwork for subsequent in vitro and in vivo studies, advancing the development of microbiome-based intervention strategies.","PeriodicalId":8736,"journal":{"name":"Artificial Cells, Nanomedicine, and Biotechnology","volume":"54 1","pages":"305-320"},"PeriodicalIF":5.6,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148410271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retraction Statement: Long non-coding RNA LINC00858 promotes cells proliferation, migration and invasion by acting as a ceRNA of miR-22-3p in colorectal cancer. 撤回声明：长链非编码RNA LINC00858在结直肠癌中作为miR-22-3p的ceRNA促进细胞增殖、迁移和侵袭。

IF 5.6 3区生物学

Artificial Cells, Nanomedicine, and Biotechnology Pub Date : 2026-12-01 Epub Date: 2026-07-28 DOI: 10.1080/21691401.2026.2708505

引用次数: 0