Avian DiseasesPub Date : 2023-01-26DOI: 10.1637/0005-2086-66.4.506
{"title":"Avian Pathology Volume 51 Number 5 October 2022 Table of Contents","authors":"","doi":"10.1637/0005-2086-66.4.506","DOIUrl":"https://doi.org/10.1637/0005-2086-66.4.506","url":null,"abstract":"","PeriodicalId":8667,"journal":{"name":"Avian Diseases","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45415296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avian DiseasesPub Date : 2023-01-26DOI: 10.1637/0005-2086-66.4.508
{"title":"Avian Pathology Volume 52 Number 1 February 2023 Table of Contents","authors":"","doi":"10.1637/0005-2086-66.4.508","DOIUrl":"https://doi.org/10.1637/0005-2086-66.4.508","url":null,"abstract":"","PeriodicalId":8667,"journal":{"name":"Avian Diseases","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43183979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avian DiseasesPub Date : 2022-12-01DOI: 10.1637/aviandiseases-D-22-00038
Giuseppe Giglia, Elvio Lepri, Margherita Orlandi, Ilaria Porcellato, Isabella Costantino, Elisa Rampacci, Fabrizio Passamonti, Maria Teresa Mandara, Valentina Stefanetti
{"title":"Inclusion Body Disease and Columbid Alphaherpesvirus 1 Infection in a Eurasian Eagle-Owl (<i>Bubo bubo</i>) of Central Italy.","authors":"Giuseppe Giglia, Elvio Lepri, Margherita Orlandi, Ilaria Porcellato, Isabella Costantino, Elisa Rampacci, Fabrizio Passamonti, Maria Teresa Mandara, Valentina Stefanetti","doi":"10.1637/aviandiseases-D-22-00038","DOIUrl":"https://doi.org/10.1637/aviandiseases-D-22-00038","url":null,"abstract":"<p><p>Hepatosplenitis or inclusion body disease is a fatal disease in owls caused by Columbid alphaherpesvirus 1 (CoHV-1). A few old case reports describe it worldwide. In Italy, knowledge regarding virus circulation and disease development is lacking. Four Eurasian eagle-owls (<i>Bubo bubo</i>), two adults and two juveniles, were submitted for postmortem examination showing aspecific clinical signs a few hours before death. Grossly disseminated petechial hemorrhages on serosal surfaces (<i>n</i> = 4), hepatic and splenic necrosis (<i>n</i> = 3), bilateral and symmetric necrosis of pharyngeal tonsils (<i>n</i> = 2), and diffuse and bilateral dark-red discoloration and firmness in lungs (<i>n</i> = 2) were seen. Tissues were sampled for histology, bacteriology, molecular testing, and transmission electron microscopy (TEM). On histology, disseminated petechial hemorrhages (<i>n</i> = 4) and necrosis of liver (<i>n</i> = 3) and spleen (<i>n</i> = 3) were seen, as well as lympho-histiocytic interstitial pneumonia and meningoencephalitis (<i>n</i> = 2). Intranuclear inclusion bodies (INIBs) were detected in one case. A panherpesviral PCR led to positive results in one case, identified in sequencing as CoHV-1. On TEM, intranuclear and intracytoplasmic virions with herpesviral morphology were seen in the same case. For the other three birds, the lack of PCR positivity, INIBs, and TEM detection could be linked to a possible reduction of the virus to undetectable levels. Death possibly occurred secondarily to bacterial infections, supposedly established during the acute phase of CoHV-1 infection. This paper reports the presence of CoHV-1in Italy and the development of a fatal form of the disease in a Eurasian eagle-owl.</p>","PeriodicalId":8667,"journal":{"name":"Avian Diseases","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10719567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avian DiseasesPub Date : 2022-12-01DOI: 10.1637/aviandiseases-D-22-99992
W H Dawe, D R Kapczynski, E G Linnemann, V R Gauthiersloan, H S Sellers
{"title":"Analysis of the Immune Response and Identification of Antibody Epitopes Against the Sigma C Protein of Avian Orthoreovirus Following Immunization with Live or Inactivated Vaccines.","authors":"W H Dawe, D R Kapczynski, E G Linnemann, V R Gauthiersloan, H S Sellers","doi":"10.1637/aviandiseases-D-22-99992","DOIUrl":"https://doi.org/10.1637/aviandiseases-D-22-99992","url":null,"abstract":"<p><p>Avian orthoreoviruses are causative agents of tenosynovitis and viral arthritis in both chickens and turkeys. Current commercial reovirus vaccines do not protect against disease caused by emerging variants. Custom-made inactivated reovirus vaccines are commonly utilized to help protect commercial poultry against disease. Antibody epitopes located on the viral attachment protein, σC, involved in virus neutralization, have not been clearly identified. In this study, the S1133 vaccine strain (Genetic Cluster 1 [GC1], a GC1 field isolate (117816), and a GC5 field isolate (94826) were determined to be genetically and serologically unrelated. In addition, chickens were vaccinated with either a commercial S1133 vaccine, 117816 GC1, or 94826 GC5, and sera were used in peptide microarrays to identify linear B-cell epitopes within the σC protein. Specific-pathogen-free (SPF) chickens were vaccinated twice with either: 1) live and live, 2) inactivated and inactivated, or 3) a combination of live and inactivated vaccines. Epitope mapping was performed on individual serum samples from birds in each group using S1133, 117816, and 94826 σC sequences translated into an overlapping peptides and spotted onto microarray chips. Vaccination with a combination of live and inactivated viruses resulted in a greater number of B-cell binding sites on the outer-capsid domains of σC for 117816 and 94826, but not for S1133. In contrast, the S1133-vaccinated birds demonstrated fewer epitopes, and those epitopes were located in the stalk region of the protein. However, within each of the vaccinated groups, the highest virus-neutralization titers were observed in the live/inactivated groups. This study demonstrates differences in antibody binding sites within σC between genetically and antigenically distinct reoviruses and provides initial antigenic characterization of avian orthoreoviruses and insight into the inability of vaccine-induced antibodies to provide adequate protection against variant reovirus-induced disease.</p>","PeriodicalId":8667,"journal":{"name":"Avian Diseases","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10731698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}