意大利中部欧亚鹰鸮(Bubo Bubo)包涵体病和柱状α疱疹病毒1型感染。

IF 1.3 4区 农林科学 Q2 VETERINARY SCIENCES
Giuseppe Giglia, Elvio Lepri, Margherita Orlandi, Ilaria Porcellato, Isabella Costantino, Elisa Rampacci, Fabrizio Passamonti, Maria Teresa Mandara, Valentina Stefanetti
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引用次数: 0

摘要

肝脾炎或包涵体病是由CoHV-1引起的猫头鹰致命性疾病。一些旧的病例报告在世界范围内描述了它。在意大利,缺乏关于病毒传播和疾病发展的知识。4只欧亚鹰鸮(Bubo Bubo), 2只成年猫头鹰和2只幼鹰猫头鹰,在死亡前几小时被送去验尸,表现出特定的临床症状。浆膜表面弥散性斑点性出血(n = 4),肝和脾坏死(n = 3),双侧和对称性咽扁桃体坏死(n = 2),肺弥漫性和双侧暗红色变色和硬化(n = 2)。组织取样进行组织学、细菌学、分子检测和透射电镜(TEM)检查。组织学上可见弥散性点状出血(n = 4),肝(n = 3)和脾(n = 3)坏死,以及淋巴组织细胞间质性肺炎和脑膜脑炎(n = 2)。1例检出核内包涵体(inib)。panherpesviral PCR在一个病例中导致阳性结果,测序鉴定为CoHV-1。在透射电镜下,在同一病例中可以看到具有疱疹病毒形态的核内和胞浆内病毒体。对于其他三只鸟,缺乏PCR阳性,inib和TEM检测可能与病毒可能降低到无法检测到的水平有关。死亡可能继发于细菌感染,据推测是在CoHV-1感染的急性期发生的。本文报道了cohv -1在意大利的存在,以及在欧亚鹰鸮中出现的一种致命形式的疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Inclusion Body Disease and Columbid Alphaherpesvirus 1 Infection in a Eurasian Eagle-Owl (Bubo bubo) of Central Italy.

Hepatosplenitis or inclusion body disease is a fatal disease in owls caused by Columbid alphaherpesvirus 1 (CoHV-1). A few old case reports describe it worldwide. In Italy, knowledge regarding virus circulation and disease development is lacking. Four Eurasian eagle-owls (Bubo bubo), two adults and two juveniles, were submitted for postmortem examination showing aspecific clinical signs a few hours before death. Grossly disseminated petechial hemorrhages on serosal surfaces (n = 4), hepatic and splenic necrosis (n = 3), bilateral and symmetric necrosis of pharyngeal tonsils (n = 2), and diffuse and bilateral dark-red discoloration and firmness in lungs (n = 2) were seen. Tissues were sampled for histology, bacteriology, molecular testing, and transmission electron microscopy (TEM). On histology, disseminated petechial hemorrhages (n = 4) and necrosis of liver (n = 3) and spleen (n = 3) were seen, as well as lympho-histiocytic interstitial pneumonia and meningoencephalitis (n = 2). Intranuclear inclusion bodies (INIBs) were detected in one case. A panherpesviral PCR led to positive results in one case, identified in sequencing as CoHV-1. On TEM, intranuclear and intracytoplasmic virions with herpesviral morphology were seen in the same case. For the other three birds, the lack of PCR positivity, INIBs, and TEM detection could be linked to a possible reduction of the virus to undetectable levels. Death possibly occurred secondarily to bacterial infections, supposedly established during the acute phase of CoHV-1 infection. This paper reports the presence of CoHV-1in Italy and the development of a fatal form of the disease in a Eurasian eagle-owl.

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来源期刊
Avian Diseases
Avian Diseases 农林科学-兽医学
CiteScore
2.40
自引率
7.10%
发文量
80
审稿时长
3 months
期刊介绍: Avian Diseases is an international journal dedicated to publishing original basic or clinical research of the highest quality from various disciplines including microbiology, immunology, pathology and epidemiology. Papers on avian diseases relevant to etiology, pathogenesis, diagnosis, treatment, and control are accepted. Manuscripts dealing with avian species other than poultry will be considered only if the subject is relevant to poultry health.
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