禽呼肠孤病毒在商品肉鸡生产中的现场控制。

IF 1.3 4区 农林科学 Q2 VETERINARY SCIENCES
Tyler C Gamble, Holly S Sellers
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引用次数: 1

摘要

由于目前市售疫苗缺乏保护作用,在商业肉鸡生产中预防由变异型禽呼肠孤病毒引起的腱鞘炎/病毒性关节炎变得越来越具有挑战性。近年来从腱鞘炎/病毒性关节炎临床病例中分离出的禽呼肠孤病毒在抗原性上与美国几乎所有经商业许可的改性活的和灭活的生物制剂不同。新变体的出现可能是由于缺乏同源保护加上选择压力的影响,导致禽呼肠孤病毒的抗原性多样化。家禽业可用的一种工具是使用自体(定制)疫苗。尽管这些方法可能是有效的,但从临床病例中分离、鉴定和筛选分离株对于选择将其纳入这些疫苗中至关重要。由于没有治疗选择,控制只能通过预防感染来实现。为实现这一目标,需要具有抗原性适用性的商业许可产品和广泛交叉保护的疫苗株。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Field Control of Avian Reoviruses in Commercial Broiler Production.

Prevention of tenosynovitis/viral arthritis caused by variant avian reoviruses within commercial broiler production has become increasingly more challenging because of the lack of protection afforded by the current commercially available vaccines. Avian reoviruses isolated from clinical cases of tenosynovitis/viral arthritis in recent years are antigenically distinct from nearly all of the commercially licensed modified live and inactivated biologics available in the United States. The emergence of new variants is likely shaped by a lack of homologous protection coupled with selection pressure influences and results in antigenically diverse populations of avian reoviruses. One tool available to the poultry industry is the use of autogenous (custom) vaccines. Although these can be effective, isolation, characterization, and screening of isolates from clinical cases is paramount for the selection of isolates to include in these vaccines. With no treatment options, control can only be attained via prevention of infection. To achieve this goal, commercially licensed products with antigenic applicability and broadly cross-protective vaccine strains are needed.

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来源期刊
Avian Diseases
Avian Diseases 农林科学-兽医学
CiteScore
2.40
自引率
7.10%
发文量
80
审稿时长
3 months
期刊介绍: Avian Diseases is an international journal dedicated to publishing original basic or clinical research of the highest quality from various disciplines including microbiology, immunology, pathology and epidemiology. Papers on avian diseases relevant to etiology, pathogenesis, diagnosis, treatment, and control are accepted. Manuscripts dealing with avian species other than poultry will be considered only if the subject is relevant to poultry health.
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