Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion最新文献_第2页

PRESTORAGE LEUKOCYTE REDUCTION WITH IN-LIN FILTRATION SYSTEM FOR WHOLE BLOOD (Sepacell Integra MAP): EVALUATION OF SYSTEM EFFICIENCY AND BLOOD PRODUCTS 用IN-LIN全血过滤系统减少储存前白细胞:系统效率和血液制品的评价

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2010-01-01 DOI: 10.3925/jjtc1958.46.521

M. Akino, S. Yamamoto, Satoshi Saikawa, Masako Satoh, Kimiko Segawa, K. Kobayashi, K. Ikebuchi, H. Ikeda

{"title":"PRESTORAGE LEUKOCYTE REDUCTION WITH IN-LIN FILTRATION SYSTEM FOR WHOLE BLOOD (Sepacell Integra MAP): EVALUATION OF SYSTEM EFFICIENCY AND BLOOD PRODUCTS","authors":"M. Akino, S. Yamamoto, Satoshi Saikawa, Masako Satoh, Kimiko Segawa, K. Kobayashi, K. Ikebuchi, H. Ikeda","doi":"10.3925/jjtc1958.46.521","DOIUrl":"https://doi.org/10.3925/jjtc1958.46.521","url":null,"abstract":"Anewly developed leukoreduction filter system for whole blood was evaluated. Whole blood was leukoreduced with the closed system(Sepacell Integra MAP), followed by centrifugation to obtain red cells and plasma(Leukocyte-reduced plasma: LR-FFP). Red cells were reconstituted with MAP solution(Leukocyte-reduced RCC: LR-RCC). Residual leukocyte counts were 1.8±1.3×105/bag after filtration and O.9±0.5×105/bag in LRRCC. These values are well below those indicated in the AABB standard and CE guideline. Erythrocyte recovery rate in Sepacell MAP was 89.1±2.3%, which was not different from that in red cell concentrate without filtration(buffy coat reduced RCC: BCR-RCC). There was no accumulation of IL-1β, IL-80r LDH in the supernatants of LR-RCC during storage. Further, there was no significant difference in electrolyte levels in the supernatant and red cell fractions during storage between LR-RCC and BCR-RCC. In LR-FFP, elevation of C3a was observed in 2 0f 6 samples, while elevation of LDH was not observed.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70331187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

PROSPECTIVE STUDY ON THE DEVELOPMENT OF ALLOIMMUNE THROMBOCYTOPENIA IN NEONATES BORN TO MOTHERS WITH ANTI-HPA-4B 抗hpa - 4b母亲所生新生儿同种免疫性血小板减少症发展的前瞻性研究

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2010-01-01 DOI: 10.3925/jjtc1958.46.463

Chikako Takeuchi, H. Ohto, T. Yamaguchi, Y. Tohyama, O. Yamaguchi, S. Morita, Takayuki, Enomoto, K. Hando, A. Ishijima, S. Imamura, K. Fujimori, Mitsuru Sugafuji, K. Takasaki, Kazuo Ohsugi, Nobuhiro Yosimatu, Eiji Sato, K. Nemoto, S. Kin, Takao Yosida, Tatsuro, Azuma, A. Sato

引用次数: 0

RE-EXAMINATION OF BERNSTEIN'S CORRECTIONS TO THE MULTI-ALLELOMORPHISM IN THE ABO BLOOD GROUPS 伯恩斯坦对abo血型多重同形性修正的再检验

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2010-01-01 DOI: 10.3925/jjtc1958.34.391

Miyoji Amemiya

{"title":"RE-EXAMINATION OF BERNSTEIN'S CORRECTIONS TO THE MULTI-ALLELOMORPHISM IN THE ABO BLOOD GROUPS","authors":"Miyoji Amemiya","doi":"10.3925/jjtc1958.34.391","DOIUrl":"https://doi.org/10.3925/jjtc1958.34.391","url":null,"abstract":"We propose a primarily algebraic equation (I) for Bernstein's corrections2, which was invented through the method of conversion of variables in 1930. He proved the following conditions: ai+c+al =a2+c+a2=2 pipi+2rpp+2r z2 which can be also obtained by differentiating the logarithm of Bernoulli's probability expression. Therefore, they may be said the conditions for the maximum likelihood methods. They may be logically correct, but pi(BO)=1-s, /1-ai-cij was alone adopted asa raw estimate, because of which the range of the least x2 solution was limited between pi(BO°) and pi(SO). It is the same in the case of the GC method, too. But there are some distributions which follow the AO method. The BE and GC methods neglected the AO raw estimates, so that such limitation was brought about. On the other hand, as the AO method also neglected the heterozygote, the precise answer cannot be obtained. But the SW corrected equation extends the range of the least x2 solution by using 2w1D or 4wiD in the equation (I), and gives the adequate answer to the AB-existentdistributions following the AO method. Therefore, the SW and SK corrected methods give the least x2 approximations superior to the BE and GC ones by the primarily algebraic idea only.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70303796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A NEW ADDITIVE SOLUTION CONTAINING PHOSPHOENOLPYRUVATE (PEP) FOR PLASMA AND LEUKOCYTE POOR RED CELL CONCENTRATES I. PEP for Red Cells Preservation as a Protein-Free-Medium 一种新的含磷酸烯醇丙酮酸(PEP)的血浆和白细胞差的红细胞浓缩物添加剂溶液

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2010-01-01 DOI: 10.3925/jjtc1958.34.64

M. Shiba, S. Sasakawa, N. Hamasaki, Shinichiro Uchiumi, M. Shimizu

{"title":"A NEW ADDITIVE SOLUTION CONTAINING PHOSPHOENOLPYRUVATE (PEP) FOR PLASMA AND LEUKOCYTE POOR RED CELL CONCENTRATES I. PEP for Red Cells Preservation as a Protein-Free-Medium","authors":"M. Shiba, S. Sasakawa, N. Hamasaki, Shinichiro Uchiumi, M. Shimizu","doi":"10.3925/jjtc1958.34.64","DOIUrl":"https://doi.org/10.3925/jjtc1958.34.64","url":null,"abstract":"A NEW ADDITIVE SOLUTION CONTAINING PHOSPHOENOLPYRUVATE (PEP) FOR PLASMA AND LEUKOCYTE POOR RED CELL CONCENTRATES I. PEP for Red Cells Preservation as a Protein-Free-Medium Masayuki Shiba1), Shigeru Sasakawa1), Naotaka Hamasaki2), Shinichirou Uchiumi3 and Masaru Shimizu4 1) Japanese Red Cross Central Blood Center 2) Department of Biochemistry, Fukuoka University, School of Medicine 3) Ube Industries, Co. Ltd. 4) Transfusion Service, Tokyo Women's Medical College In recent blood banking, a totally improved red cell product is required, such as, leukocyte depletion for decreasing of transfusion reaction and maintenance of both ATP, for posttransfusional viability, and 2, 3-diphosphoglycerate (2, 3-DPG), for oxygen-delivering, are necessary. Phosphoenolpyruvate (PEP) is known to increase both ATP and 2, 3-DPG levels in red cells. We applied it to the additive solution as a protein-free-medium for the preservation of plasma and leukocyte poor red cell concentrates. Plasma and leukocyte poor red cell concentrates were prepared by re-centrifugation (4,000G, 6 minutes). Over 80% of leukocytes were removed and 60ml of plasma was collected from 1 unit of concentrated red cells (400ml collection). During 6 weeks storage, ATP and 2, 3-DPG levels of stored red cells in the new additive solution containing maltose, citrate, phosphate, adenine and PEP, were kept very well. After 6 weeks storage, ATP and 2, 3-DPG levels were 80% and 50% of fresh ones, respectively, by incubation at 37C for 30 minutes. Furthermore, the stored red cell shapes were retained discoid and hemolysis decreased. This additive solution enabled red cell preparations to be stored at least for up to 42 days and to provide an excellent red cell product, which was advantageous for patients to receive red cells with a normal oxygen affinity, a long shelf life in vivo and decreasing of transfusion reaction.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70305611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HEMATOLOGICAL, METABOLIC AND RHEOLOGICAL CHARACTERISTICS OF ERYTHROCYTES IN RECOMBINANT HUMAN ERYTHROPOIETIN-ADMINISTERED RAT II. Rheological Properties 重组人促红细胞生成素大鼠红细胞的血液学、代谢和流变学特性研究ii。流变特性

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2010-01-01 DOI: 10.3925/jjtc1958.35.633

N. Maeda

引用次数: 0

CROSS REACTING METERIAL POSITIVE TYPE FACTOR VII ABNORMALITY 交叉反应物质阳性型因子vii异常

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2010-01-01 DOI: 10.3925/jjtc1958.38.463

Shinya, Kimural, Kazuo, Ochil, Shogo, Yamamotol, Naoyuki, Maruo, Motoharu, Kondo, Sadaaki, Mikami, Osamu, Takamiya

引用次数: 0

EVALUATION OF COMMERCIAL KIT, ANTI-PLT-OLYBIO-MPHA FOR THE DETECTABILITY OF ANTI-HLA ANTIBODIES: Comparison with the Lymphocyte Cytotoxicity Test and Flow Cytometry ANTI-PLT-OLYBIO-MPHA商用试剂盒对hla抗体检测能力的评价:与淋巴细胞毒性试验和流式细胞术的比较

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2010-01-01 DOI: 10.3925/jjtc1958.39.703

Keisuke, Nagamine, Satoru, Hayashi, Yoshiyuki, Kurata

引用次数: 0

PREVENTION OF RECOMBINANT HUMAN GRANULOCYTE COLONY STIMULATING FACTOR (rhG-CSF; FILGRASTIM) ADSORPTION BY ADDITION OF MULTI-VITAMIN MIXTURE 重组人粒细胞集落刺激因子(rhG-CSF)的预防复合维生素混合物的吸附

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2010-01-01 DOI: 10.3925/jjtc1958.42.162

Mami, Ohtsuka, Noriko, Usui, Yumi, Arai, Saho, Harada, Kaoru, Iwagami, Yumiko, Kurata, Kiyoko, Maeda, Michio, Matsuzaki, Hiroshi, Mohri, Takao, Okubo

{"title":"PREVENTION OF RECOMBINANT HUMAN GRANULOCYTE COLONY STIMULATING FACTOR (rhG-CSF; FILGRASTIM) ADSORPTION BY ADDITION OF MULTI-VITAMIN MIXTURE","authors":"Mami, Ohtsuka, Noriko, Usui, Yumi, Arai, Saho, Harada, Kaoru, Iwagami, Yumiko, Kurata, Kiyoko, Maeda, Michio, Matsuzaki, Hiroshi, Mohri, Takao, Okubo","doi":"10.3925/jjtc1958.42.162","DOIUrl":"https://doi.org/10.3925/jjtc1958.42.162","url":null,"abstract":"Using a system which simulates actual conditions in continuous intravenous infusion, we evaluated the adsorption of recombinant human granulocyte colony stimulating factor (rhG-CSF; filgrastim) in an intravenous administration system and investigated potential adsorption inhibitors. Filgrastim concentration in the infusion solution was determinated by ELISA. Multiple vitamin mixtures used as potential adsorption inhibitors were effective in inhibiting adsorption with varying degrees of efficacy.Polysorbate 80, surface active substance and human serum albumin also prevented adsorption.Comparison of effects among multiple vitamin mixtures suggested that the major determinate of inhibition of adsorption was polysorbate 80 concentration. With regard to infusion system, filter type and container size both shown to influence filgrastim adsorption, whereas tube length did not. Filgrastim adsorption was remarkably decreased by combination with multiple vitamin mixtures containing polysorbate 80.This method is recommended as a mean of reducing filgrastim adsorption in intravenous infusion systems.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70324837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

LEUKOREDUCED PLATELET CONCENTRATES BY THE COBE SPECTRA LEUKOREDUCTION SYSTEM PREVENT SEVERE ANAPHYLACTIC REACTIONS ASSOCIATED WITH PLATELET TRANSFUSION THROUGH LEUKOCYTE REMOVAL FILTERS: TWO CASE REPORTS cobe光谱白细胞诱导系统的白细胞诱导血小板浓缩物通过白细胞去除过滤器防止与血小板输注相关的严重过敏反应:两例报告

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2010-01-01 DOI: 10.3925/jjtc1958.45.379

Yasuhiko Fujiil, Y. Azuno, Masasi Ookubo, Y. Ooba, Y. Oka

引用次数: 0

THE EFFECT OF GLYCEROL-3-PHOSPHATE ON STORAGE OF CPD PRESERVED WHOLE BLOOD 甘油-3-磷酸对CPD全血保存的影响

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2010-01-01 DOI: 10.3925/jjtc1958.33.349

Michio Kawashima, M. Tsubokura

{"title":"THE EFFECT OF GLYCEROL-3-PHOSPHATE ON STORAGE OF CPD PRESERVED WHOLE BLOOD","authors":"Michio Kawashima, M. Tsubokura","doi":"10.3925/jjtc1958.33.349","DOIUrl":"https://doi.org/10.3925/jjtc1958.33.349","url":null,"abstract":"Michio Kawashima and Michio Tsubokura Japanese Red Cross Tokyo Metropolitan Blood Center Adenosine triphosphate (ATP) and 2,3-diphosphoglycerate (2,3-DPG) are closely related to the functions of erythrocytes. We studied the effect of glycerol-3-phosphate on the levels of ATP and 2,3-DPG in erythrocyte. A single bag of donor blood was equally divided into two parts and glycerol-3-phosphate was added to one part. The other part was used as a control. We measured ATP, 2,3-DPG, plasma glucose, plasma lactate and the osmotic resistance levels of erythrocyte to evaluate the function of erythrocytes. As the results of these analyses, in the part to which glycerol-3-phosphate was added, ATP level showed 78.7% after three weeks and it maintained high level of 74.4% after five weeks. 2,3-DPG level showed 33.2% after three weeks, showing high value as compared with that of the control. And plasma glucose reduced rapidly while plasma lactate raised correspondingly, indicating that high activity was maintained in glucose metabolism. The osmotic resistance of erythrocytes also maintained good condition even after five weeks. These data suggest that the addition of glycerol-3-phosphate for storage of CPD preserved whole blood is effective to maintaine the function of erythrocyte.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70301859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0