Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion最新文献_第10页

PERIOPERATIVE USE OF BLOOD COMPONENTS DURING HEART, LUNG AND PANCREAS-KIDNEY TRANSPLANTATION FROM BRAIN-DEAD DONORS 脑死亡供体心脏、肺和胰脏肾移植围手术期血液成分的使用

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2004-01-01 DOI: 10.3925/JJTC1958.50.699

T. Kiyokawa, M. Oshida, K. Nagamine, S. Hayashi, Y. Kurata

引用次数: 1

VISUAL IDENTIFICATION OF Serratia liquefaciens -CONTAMINATED RED BLOOD CELLS 液化沙雷菌污染红细胞的目视鉴别

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2004-01-01 DOI: 10.3925/jjtc1958.50.613

Sayoko Sugiura, Takayoshi Yamada, C. Inoue, Syozo Nakashima, K. Ozawa, and Tadashi Kamiya

{"title":"VISUAL IDENTIFICATION OF Serratia liquefaciens -CONTAMINATED RED BLOOD CELLS","authors":"Sayoko Sugiura, Takayoshi Yamada, C. Inoue, Syozo Nakashima, K. Ozawa, and Tadashi Kamiya","doi":"10.3925/jjtc1958.50.613","DOIUrl":"https://doi.org/10.3925/jjtc1958.50.613","url":null,"abstract":"Lethal transfusion reactions due to Serratia liquefaciens have been reported. To study the growth of this organism, 4 RBCs were inoculated with 1 or 10 colony forming units (cfu) /bag of Serratia liquefaciens (each concentration, 11=2) and stored at 5.6C . Each of the inoculated RBCs showed an apparent darkening in color on day 10 (10 cfu/bag) or 11 (1 cfu/bag). At that time, the number of Serratia liquefaciens had increased to 8.3 X 10 and 2.7 X 108 cfu/m 1, respectively. We then used a chroma meter to evaluate the change in RBC color more objectively and also photographed the samples for the three-week storage period. Supernatant Hb levels increased rapidly after day 7 and were 14.3 g/dl on day 10 (1 cfu/bag). Endotoxin was detected after day 9. These findings indicate that Serratia liquefaciens showed strong growth in RBCs stored at 5.6t, and that this proliferation of bacteria was associated with an increase in supernatant Hb and endotoxin level followed by darkening in color of RBCs. Although discoloration is not an early index of Serratia liquefaciens contamination of RBCs, pretransfusion visual inspection may contribute to reducing the risk of transfusion-related sepsis.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3925/jjtc1958.50.613","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70335708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COMPATIBILITY TEST OF HEMATOPOIETIC STEM CELL BANK IN JAPAN 日本造血干细胞库相容性试验

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2004-01-01 DOI: 10.3925/jjtc1958.50.93

Y. Ishikawa

引用次数: 0

PRACTICAL BLOOD TRANSFUSION MEDICINE EDUCATION OF MEDICAL STUDENTS AT A REGIONAL BLOOD CENTER 某地区血站医学生实用输血医学教育

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2004-01-01 DOI: 10.3925/jjtc1958.50.68

K. Nibu, Y. Maeda

{"title":"PRACTICAL BLOOD TRANSFUSION MEDICINE EDUCATION OF MEDICAL STUDENTS AT A REGIONAL BLOOD CENTER","authors":"K. Nibu, Y. Maeda","doi":"10.3925/jjtc1958.50.68","DOIUrl":"https://doi.org/10.3925/jjtc1958.50.68","url":null,"abstract":"We evaluated the practical education of 5th grader medical students at a regional blood center concerning various aspects of blood transfusion.Practical education consisted of observation of voluntary blood donation, assistance in publicity of blood donation center, learning how to collect and prepare various blood products free of contami nation with infectious agents, contamination, performing blood typing as well as cross-matching and viewing short video lectures to avoid blood transfusion mismatches. The program has begun from 1987. Fifth grader students were surveyed to determine the effectiveness of this program at the end of the school year. Most students responded that they had improved their understanding of blood transfusion; in particular, they realized that blood products are obtained through the combined big efforts of volunteer donors and blood center workers. They also recognized that, as future doctors, they must minimize the use of blood products to avoid possible adverse side effects and also to ensure self-sufficiency of blood products in Japan. The level of understanding achieved through this practical program in the 5th grader was markedly better than that achieved by lectures to students in the first 3rd grader of medical school.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"50 1","pages":"68-72"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70335514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SUCCESSFUL CHEMOTHERAPY AND ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN A CASE OF ACUTE MYELOID LEUKEMIA WITH IgA DEFICIENCY 急性髓系白血病伴IgA缺乏症1例化疗及异基因造血干细胞移植成功

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2004-01-01 DOI: 10.3925/jjtc1958.50.714

K. Nagai, E. Matsuo, J. Inoue, M. Fujii, E. Shimada, S. Mitsunaga, Yoshihisa Watanabe, T. Fukushima, Y. Miyazaki, Y. Fukahori, S. Nakashima, S. Chiyoda, M. Tomonaga, S. Kamihira

{"title":"SUCCESSFUL CHEMOTHERAPY AND ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN A CASE OF ACUTE MYELOID LEUKEMIA WITH IgA DEFICIENCY","authors":"K. Nagai, E. Matsuo, J. Inoue, M. Fujii, E. Shimada, S. Mitsunaga, Yoshihisa Watanabe, T. Fukushima, Y. Miyazaki, Y. Fukahori, S. Nakashima, S. Chiyoda, M. Tomonaga, S. Kamihira","doi":"10.3925/jjtc1958.50.714","DOIUrl":"https://doi.org/10.3925/jjtc1958.50.714","url":null,"abstract":"Deficiency of IgA with circulating class-specific anti-IgA antibodies is one of the major causes of anaphylactic reaction in transfusion medicine. This problem is more serious in the management of patients with hematological malignancies or other types of bone marrow failure. Here we report a case of acute myeloid leukemia with IgA deficiency who underwent intensive chemotherapy and allogeneic bone marrow transplantation. To avoid the production of anti-IgA antibody, platelet concentrates were collected from donors who were IgA-deficient. Additional support with platelets and RBC components from donors who had circulating IgA was provided using products washed and replaced with 0.9% normal saline. Complete remission was achieved after a single course of remission induction therapy. After one course of consolidation chemotherapy, allogeneic bone marrow transplantation from an HLA-matched sibling was performed. No anaphylactic reaction was observed after any transfusion. No circulating anti-IgA antibodies were detectable after the full recovery of hematopoiesis in this patient. These findings indicate that allogeneic blood component products collected from donors with IgA deficiency are useful in myeloablative therapy in patients with hematological disorders. By washing with normal saline, products from donors with normal IgA levels are also acceptable. Further studies to elucidate the clinical usefulness of precise genomic and expressional analysis of IgA gene are required to ensure the safety of transfusion medicine in patients with IgA deficiency. Furthermore, the establishment of blood bank registry systems for IgA-deficient blood donors is important to the maintenance of a stable supply of blood components for IgA-deficient patients who require transfusion therapy.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"50 1","pages":"714-719"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70335896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EVALUATION OF QUALITIES ON A CLOSED SYSTEM USING THE WHOLE BLOOD LEUKOCYTE DEPLETION FILTER (WBF) FOR PRE-STORAGE 使用全血白细胞滤清器(wbf)进行预储存的封闭系统的质量评价

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2004-01-01 DOI: 10.3925/JJTC1958.50.56

R. Yasunaga, T. Yuasa, Ken-ichi Horiuchi, Yasuyuki Suzuki, M. Nohara, S. Takashima, Masanori Tanaka, A. Tanaka, Yukie Higa, Yuko Marudaka, K. Nakata, H. Sakamoto

{"title":"EVALUATION OF QUALITIES ON A CLOSED SYSTEM USING THE WHOLE BLOOD LEUKOCYTE DEPLETION FILTER (WBF) FOR PRE-STORAGE","authors":"R. Yasunaga, T. Yuasa, Ken-ichi Horiuchi, Yasuyuki Suzuki, M. Nohara, S. Takashima, Masanori Tanaka, A. Tanaka, Yukie Higa, Yuko Marudaka, K. Nakata, H. Sakamoto","doi":"10.3925/JJTC1958.50.56","DOIUrl":"https://doi.org/10.3925/JJTC1958.50.56","url":null,"abstract":"To prevent the post-transfusion reactions in transfusion therapy such as HLA alloimmunization, non-hemolytic febrile transfusion reaction (NHFTR) and Cytomegalovirus transmission, bedside leukocyte reduction has been performed. However, it has become clear that prestorage leukocyte reduction has greater efficiency than poststorage, and prestorage leukocyte reduction is now being considered for implementation. We developed a prestorage leukocyte reduction system that contains CPD anticoagulant solution (PLD-C system). In this study, the performance of the PLD-C system was examined with regard to the leukocyte filtration efficacy and the characteristics of blood during storage by comparison with a pre-storage leukocyte reduction system which uses ACD-A solution (PLD-A system) and blood components collected using CPD solution and prepared by the buffy-coat depleted method (BCPD).It was confirmed that the leukocyte reduction ratio of the PLD-C system (more than-4log) was higher than that of the BCPD (less than-0.4log). Platelet depletion rates of the PLD-C group (average more than 99%) was also higher than in the BCPD group, but the red cell recovery ratio was the same between groups (average 88%). Prestorage filtration showed no adverse effects such as hemolysis, whereas various good effects were observed, such as inhibition of macroaggregate formation and hemolysis during storage. Collecting blood into CPD solution improved red cell quality during storage and increased plasma volume compared to the ACD-A solution.It was confirmed that the PLD-C system has advantages in the production of blood components over the present system. Use of this system can be expected to prevent post transfusion reactions.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"50 1","pages":"56-67"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70335113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro におけるヘモグロビン小胞体の血小板活性化に対する影響对体外血红蛋白内质网血小板活化的影响

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2003-11-01 DOI: 10.3925/JJTC1958.49.653

若本志乃舞, 満博藤原, 英樹阿部, 美樹山口, 真司武岡, 英俊土田, 久實池田

{"title":"In vitro におけるヘモグロビン小胞体の血小板活性化に対する影響","authors":"若本志乃舞, 満博藤原, 英樹阿部, 美樹山口, 真司武岡, 英俊土田, 久實池田","doi":"10.3925/JJTC1958.49.653","DOIUrl":"https://doi.org/10.3925/JJTC1958.49.653","url":null,"abstract":"Hemoglobin vesicles (HbV), a type of liposome-encapsulated hemoglobin (LEH), have been recently developed as an artificial oxygen carrier. The efficacy of HbV has been demonstrated in the transfusion of HbV into rodent models of hemorrhagic shock. It is important to evaluate the compatibility of HbV with human blood cells. We examined the effects of HbV on human platelet activation in vitro by estimating the platelet release reaction and expression of platelet surface activation markers in the presence or absence of agonists. HbV concentration in the reaction volume was prepared at 20% or 40%. Preincubation of platelet-rich plasma (PRP) with HbV had no adverse effects on RANTES or serotonin release from platelets. Preincubation of whole blood with HbV also had no effects on exposure of P-selectin on platelets. However, binding of PAC-1, a monoclonal antibody that detects the activation-dependent conformational change of αIIbβ3 to platelets, was amplified by preincubation of whole blood with HbV in the presence of relatively low concentration of ADP. These results suggest that HbV enhances the binding of PAC-1 to platelets. The clinical meaning of this increased binding of PAC-1 needs to be addressed.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"49 1","pages":"653-659"},"PeriodicalIF":0.0,"publicationDate":"2003-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70334247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

LEUKOCYTE REDUCTION FILTERS AND INFUSION DEVICE FOR RED BLOOD CELL TRANSFUSION 红细胞输注用白细胞减少过滤器及输注装置

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2003-07-01 DOI: 10.3925/JJTC1958.49.449

Yuuji Buseki, Sakiko Morino, J. Henmi, S. Fujino, Shojiro Takagi

引用次数: 0

Escherchia coli 敗血症に合併した Acquired Bおよび Tk-polyagglutination の1例 Acquired B和Tk-polyagglutination合并Escherchia coli败血症的1例

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2003-03-01 DOI: 10.3925/JJTC1958.49.50

Makiko Ozaki, S. Matsuda, Masataka Nishiyama, Toshimi Iura, K. Matsuzaki

{"title":"Escherchia coli 敗血症に合併した Acquired Bおよび Tk-polyagglutination の1例","authors":"Makiko Ozaki, S. Matsuda, Masataka Nishiyama, Toshimi Iura, K. Matsuzaki","doi":"10.3925/JJTC1958.49.50","DOIUrl":"https://doi.org/10.3925/JJTC1958.49.50","url":null,"abstract":"We report on a patient who developed acquired B antigen and Tk polyagglutination in Escherichia coli（ Ec oli）septicaemia during the course of ulcerative colitis. In vitro analysis showed that Ec oliwas the cause of the acquired B phenomenon. The level of intensity of both Tk and acquired B antigen changed simultaneously and both disappeared at the same time. Both antigens were also abolished by acetylation of the patient’ s red blood cells. These findings indicate that the Tk polyagglutination was closely related to the acquired B antigen. H activity decreased during the course of hospitalization. From the results of acetylation of the patient’ s red blood cells the decrease in H activity was explained by the fact that acquired B‑and Tk‑expressing red blood cells showed stronger than H activity of A1 red blood cells. The antigenic modification appeared prior to the onset of Ec olisepticaemia. This finding sug‑ gests that the early detection of blood abnormalities is helpful in the early diagnosis and proper treat‑ ment of these patients.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"98 1","pages":"50-56"},"PeriodicalIF":0.0,"publicationDate":"2003-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70333805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

豊橋市民病院新生児医療センターにおける交換輸血の実態 -交換輸血の問題点・注意点に関する考察- 丰桥市民医院新生儿医疗中心交换输血的实态-关于交换输血的问题点·注意点的考察-

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2003-03-01 DOI: 10.3925/JJTC1958.49.63

典久小山, 理香長崎, 崇浩杉浦, 直樹安藤, 里美河合, 朋子石黒, 幸子山口, 幹尚大林, 賀巳鈴木

{"title":"豊橋市民病院新生児医療センターにおける交換輸血の実態 -交換輸血の問題点・注意点に関する考察-","authors":"典久小山, 理香長崎, 崇浩杉浦, 直樹安藤, 里美河合, 朋子石黒, 幸子山口, 幹尚大林, 賀巳鈴木","doi":"10.3925/JJTC1958.49.63","DOIUrl":"https://doi.org/10.3925/JJTC1958.49.63","url":null,"abstract":"We conducted a survey of exchange transfusions performed in our neonatal medical center during the last 5 years.From January 1, 1996 to December 31, 2000, 2296 neonates were admitted to our neonatal nursery. Sixteen exchange transfusions were performed upon 10 infants whose birth weights ranged from 512g to 3610g. The incidence of exchange transfusion was 0.44%. The indication for each exchange transfusion was hyperbilirubinemia (eight instances), sepsis with DIC (four instances), shock with massive hemorrhage (three instances) and hydrops fetalis. Hyperkalemia was a complication in one case. Adequate blood was difficult to get in emergency situations.Exchange transfusion is one of the essential techniques in the neonatal care, although it may involve some complications including hyperkalemia, bleeding, hypocalcemia, hypoglycemia, graftversus-host disease, infections, etc., especially in very low birth weight infants. In our nursery, the incidence of exchange transfusion was very low in comparison with that of previous reports. This may represent a difference in the indication of this therapy.We propose that we should discuss the appropriate indications and safe procedures concerning exchange transfusion. We note that adequate blood supplies should be available immediately in the event of an emergency.","PeriodicalId":86521,"journal":{"name":"Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion","volume":"49 1","pages":"63-67"},"PeriodicalIF":0.0,"publicationDate":"2003-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70334131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0