Archives of Razi InstitutePub Date : 2024-06-30eCollection Date: 2024-06-01DOI: 10.32592/ARI.2024.79.3.549
C Kona, S P Kirasani, B D Kamble, R Kundapur, K Yadav, N Agarwal, V Bhatia
{"title":"Morbidity profile of the patients attending Mobile Medical Unit camps in Telangana: A record-based study.","authors":"C Kona, S P Kirasani, B D Kamble, R Kundapur, K Yadav, N Agarwal, V Bhatia","doi":"10.32592/ARI.2024.79.3.549","DOIUrl":"10.32592/ARI.2024.79.3.549","url":null,"abstract":"<p><p>Mobile Medical Units (MMUs) are one of the major initiatives under the National Rural Health Mission. These MMUs help people in remote, underserved areas access healthcare at affordable prices on their doorstep. The present record-based study aimed to assess the morbidity profile of the patients attending Mobile Medical Unit camps in the Yadadri-Bhuvanagiri district between April 2022 and December 2022. The MMU is run by the Department of Community and Family Medicine, AIIMS, Bibinagar, in six selected villages of the Yadadri-Bhuvanagiri district. A register is maintained to record the details of patients visiting the MMU camp. Patient's name, age, gender, place, mobile number, height, weight, blood pressure (BP), glucometer Random Blood Sugar, diagnosis, and details of medication dispensed were entered in the register. Diabetes, hypertension, and obesity were diagnosed using the World Health Organization (WHO) criteria, the Eighth Joint National Committee guidelines, and WHO Asia Pacific guidelines, respectively. Mobile Medical Unit Camp data are entered into the Excel database at the end of every month. Since it is a record-based analysis, we used data for analysis between April 7, 2022, and December 31, 2022. A total of 1494 patients were treated in the MMU camps during this period. Among them, 89.4% were adults, and 10.6% were children (less than 18 years). Among 1,336 adult patients, the majority of participants suffered from osteoarthritis, followed by non-communicable diseases (NCDs). The mean scores of systolic and diastolic BP of the adult population were obtained at 131±21 and 77±13 mm Hg, respectively. The mean random blood glucose level of the adult population was 150±74 mg/dl. A total of 158 children were younger than 18 years old, out of whom 78 and 80 participants were males and females, respectively. Moreover, 23.1% and 25% of males and females suffered from upper respiratory tract infections, respectively. The study further suggests that the NCD epidemic is spreading to rural areas where necessary health infrastructure is insufficient. MMUs can bring a significant change to the public health system, which needs to re-orient its priorities.</p>","PeriodicalId":8311,"journal":{"name":"Archives of Razi Institute","volume":"79 3","pages":"549-554"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archives of Razi InstitutePub Date : 2024-06-30eCollection Date: 2024-06-01DOI: 10.32592/ARI.2024.79.3.645
A Jadgalradeh, M Iqbal
{"title":"Antinociceptive and anti-inflammatory activities of the methanol extract of <i>Ferula elaeochytris</i> Korovin in a rat model.","authors":"A Jadgalradeh, M Iqbal","doi":"10.32592/ARI.2024.79.3.645","DOIUrl":"10.32592/ARI.2024.79.3.645","url":null,"abstract":"<p><p>Today, the current chemical agents used for the management of pain cause numerous complications. They are associated with the occurrence of disorders in the digestive system, damage to the kidney, or addiction, which has prompted individuals to seek novel drugs that, apart from removing the side effects, are cost-effective and available. The present <i>in vivo</i> survey aimed to assess the antinociceptive and anti-inflammatory activity of <i>Ferula elaeochytris</i> Korovin methanolic extract (FEME) in male Swiss mice. After obtaining the methanolic extract through the maceration process, the antinociceptive efficacy of FEME at doses of 25 to 100 mg/kg was assessed by the tail-flick, hot-plate, and formalin tests. Moreover, anti-inflammatory evaluation was performed using the Carrageenan-induced paw edema model. It was found that in the tail-flick and hot plate test, FEME, mainly at the dose of 100 mg/kg, significantly reduced the latency time and increased the time of the observance of licking or jumping, in comparison to normal saline (<i>P</i><0.001). We reported that FEME at 50 and 100 mg/kg significantly decreased pain behaviors in acute and chronic phases in comparison to normal saline (<i>P</i><0.001). FEME significantly declined paw edema in a dose- and time-dependent response (<i>P</i><0.05); therefore, a significant difference was observed in paw edema, followed by treatment with FEME at 50 and 100 mg/kg (<i>P</i><0.001). To conclude, this study reported the potent analgesic and inflammatory effects of FEME in controlling peripheral and central pain. Nonetheless, additional experiments are mandatory to clarify the accurate mechanisms of action of this plant.</p>","PeriodicalId":8311,"journal":{"name":"Archives of Razi Institute","volume":"79 3","pages":"645-650"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archives of Razi InstitutePub Date : 2024-06-30eCollection Date: 2024-06-01DOI: 10.32592/ARI.2024.79.3.541
S A Ghafouri, A Ghaniei, M Moghani, N Lotfalizadeh
{"title":"Newcastle Disease Vaccination Program in Broilers Using an Apathogenic Heat-Resistant Vaccine.","authors":"S A Ghafouri, A Ghaniei, M Moghani, N Lotfalizadeh","doi":"10.32592/ARI.2024.79.3.541","DOIUrl":"10.32592/ARI.2024.79.3.541","url":null,"abstract":"<p><p>Newcastle disease (ND) is among the most common and deadliest poultry diseases worldwide. Thermostable Newcastle disease virus (NDV) vaccines have been widely used to protect village chickens against ND due to their decreased dependence on cold chains for transport and storage. The NDV4 Heat-Resistant (NDV4HR) vaccine is an apathogenic, heat-resistant, live vaccine that can induce immunity in chickens. In this study, 60 one-day-old Arain local hybrid broilers were divided into three groups of 20. Group A had the usual vaccination program in broiler flocks (seven days old: B1 type by eye drop and ND killed vaccine intramuscularly; 18 and 28 days old: LaSota strain orally). Group B did not receive any vaccine, and group C received the NDV4HR vaccine orally, six times from the first day to the 35<sup>th</sup> day of rearing. All groups were nasally challenged with acute Newcastle virus (genotype VIId) on the 35<sup>th</sup> rearing day. Regarding the hemagglutination inhibition serum antibody titer of the birds after the challenge, group B had the highest (7.12±1.05), and group C (6.37±1.31) had a higher titer than group A (6±1.22). After the challenge with the Newcastle virus, the necropsy findings and clinical symptoms of the disease were almost similar in groups A and C. Group B showed the most signs, with higher casualties than other groups. Regarding weight gain, group C had the highest weight at the end of the study (2204±106). On the second day after the challenge, groups A and B had virus shedding through the trachea and cloaca, while group B shed the virus only through the trachea. Furthermore, on the seventh day after the challenge, group A shed the virus through the cloaca, whereas group B did it through the trachea and the cloaca. On the other hand, there was no virus shedding in group C. This study showed that the NDV4HR vaccine provokes an antibody response that protects the birds against a virulent virus challenge.</p>","PeriodicalId":8311,"journal":{"name":"Archives of Razi Institute","volume":"79 3","pages":"541-548"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archives of Razi InstitutePub Date : 2024-06-30eCollection Date: 2024-06-01DOI: 10.32592/ARI.2024.79.3.669
H M Al Tmimi, S A Al Dulaimi, B A Ali, H A Ghanim, Z K Alani
{"title":"Seroprevalence and detection of <i>Toxoplasma gondii</i> and <i>Echinococcus granulosus</i> in humans by indirect immunoglobulin G enzyme-linked immunosorbent assays in Baghdad.","authors":"H M Al Tmimi, S A Al Dulaimi, B A Ali, H A Ghanim, Z K Alani","doi":"10.32592/ARI.2024.79.3.669","DOIUrl":"10.32592/ARI.2024.79.3.669","url":null,"abstract":"<p><p>The present study was conducted from December 2021 to April 2023 at the College of Health and Medical Technologies, Al-Bayan University, in Baghdad province, Iraq, to detect <i>Toxoplasma gondii</i> infection in humans by serological methods. Field studies were conducted using 1,500 sera samples from hospitals and private medical laboratories. The sera samples were separated and examined by indirect immunoglobulin G enzyme-linked immunosorbent assays to serologically detect <i>T. gondii</i> infection. The serological results demonstrated that 62% of cases were positive. The present study recorded a high rate of infection in both pregnant (70.4%) and non-pregnant women (53.6%). The serological results in males illustrated a rate of 57%, while the females showed an infection rate of 65.1%, demonstrating a non-significant difference. The highest and lowest rates of infection pertained to the 30-39 (90.2%) and < 20 (25.1%) age groups, respectively. Nevertheless, 7.8% of the 192 serologically tested sera samples were positive for <i>Echinococcus granuloses</i>. Regarding the age group, the rates of infection were 10.2%, 6.6%, and 14% in the 20-29, 30-39, and > 40 age groups, respectively, with a highly significant difference with <i>E. granuloses</i>. In terms of gender, the infection rate in males was 5.7%, while it was 10.2% in females, with a highly significant difference (<i>P</i>≤0.01). Finally, regarding the months, the peak infection rate was recorded in March.</p>","PeriodicalId":8311,"journal":{"name":"Archives of Razi Institute","volume":"79 3","pages":"669-674"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archives of Razi InstitutePub Date : 2024-06-30eCollection Date: 2024-06-01DOI: 10.32592/ARI.2024.79.3.519
H Kalvandi, A Rahchamani, J Abbasi
{"title":"Interpretive Structural Modeling of the Role of the Organizational Nature on Brand Identity in the Biological Industry (A Case Study of the Razi Institute).","authors":"H Kalvandi, A Rahchamani, J Abbasi","doi":"10.32592/ARI.2024.79.3.519","DOIUrl":"https://doi.org/10.32592/ARI.2024.79.3.519","url":null,"abstract":"<p><p>This research seeks to investigate the factors related to the nature of the organization and its role in brand identity. The research was conducted in the field of biological industry. Razi Institute is the leader of the vaccine industry in terms of a variety of products and production of more than 70% of the country's market needs and is a propitious case for studying this industry. The model from the results of the qualitative method was examined using the structural equation modeling method. Because of the exploratory nature of the model and the non-normal distribution of the variables, variance-based methods were employed to predict the results of the hypotheses. The statistical population comprised 1,870 individuals, including sales representatives, inoculation centers, and veterinarians. A 40-item questionnaire was distributed among 251 participants, with an 80% response rate. The adequacy of this tool was confirmed using Bartlett's sphericity test. The variables of the model included eight exogenous latent (independent) variables, two endogenous latent (dependent) variables, two moderating variables, and one mediating variable. A total of 15 hypotheses related to relationships between variables were examined in various internal and external model analysis tests. In the end, the hypotheses were checked through factor loadings and impact factors. The variables of the model with a coefficient of determination of 0.731 could predict the model at a close-to-strong level. The obtained fit (goodness-of-fit=0.593) showed that the model had high reliability and tested the hypotheses with 97% precision.</p>","PeriodicalId":8311,"journal":{"name":"Archives of Razi Institute","volume":"79 3","pages":"519-528"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archives of Razi InstitutePub Date : 2024-06-30eCollection Date: 2024-06-01DOI: 10.32592/ARI.2024.79.3.491
F Zakikhani, S Afshar, H Fattahi, J Taghinejad
{"title":"Isolation and Molecular Identification of <i>Deoxynivalenol</i>- and <i>Fumonisin</i>-producing Genes from Maize Feed Contaminated with <i>Fusarium</i> Fungus in Silos of Dairy Farms in Fars province, Iran.","authors":"F Zakikhani, S Afshar, H Fattahi, J Taghinejad","doi":"10.32592/ARI.2024.79.3.491","DOIUrl":"10.32592/ARI.2024.79.3.491","url":null,"abstract":"<p><p>Mycotoxins are toxins produced by various types of fungi, including <i>Fusarium</i>, which can produce different types of mycotoxins, such as Deoxynivalenol (DON), Zearalenone, T-2 toxin, and Fumonisins (FUM). Mycotoxins have the potential to reduce the quality of crops and pose health risks to both humans and animals. This can result in reduced animal production and substantial economic consequences on a global scale. Extensive research has been carried out to investigate the high incidence of contamination in grains by <i>Fusarium</i> fungi. In this study, 80 samples of maize from silos of dairy farms in Fars province, Iran were collected and examined for fungal contamination by <i>Fusarium</i> and potential production of DON and FUM. For this purpose, identification using specific primers for different genes was carried out by polymerase chain reaction test and gel electrophoresis with agarose (1%). Among different counties, the silos in Kharameh with 47.05% and Jahrom with 46.15% had the highest contamination rates, and the lowest contamination rate belonged to Kazeroon with 27.27%. Out of the 30 positive samples contaminated by <i>Fusarium</i>, 21 produced FUM, 4 produced DON, and 5 produced both toxins. <i>Fusarium</i> species that contaminated the maize samples were also identified, including 13, 10, and 7 samples contaminated by <i>F. proliferatum</i>, <i>F. verticillioides</i>, and <i>F. graminearum</i>, respectively. As a conclusion, the findings of the study indicated that 37.5% of the corn samples from dairy farm silos in Fars province were contaminated with the <i>Fusarium</i> fungus, which had the potential to produce the toxic mycotoxins, deoxynivalenol, and fumonisins.</p>","PeriodicalId":8311,"journal":{"name":"Archives of Razi Institute","volume":"79 3","pages":"491-498"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archives of Razi InstitutePub Date : 2024-06-30eCollection Date: 2024-06-01DOI: 10.32592/ARI.2024.79.3.445
A Ebrahimi Ahmadabad, N Taeifi Nasrabadi, Z Momeni, B Shemshadi
{"title":"Prevalence of <i>Trichomonas gallinae</i> in Birds of Iran and its Pathological Findings: A Review study.","authors":"A Ebrahimi Ahmadabad, N Taeifi Nasrabadi, Z Momeni, B Shemshadi","doi":"10.32592/ARI.2024.79.3.445","DOIUrl":"10.32592/ARI.2024.79.3.445","url":null,"abstract":"<p><p><i>Trichomonas gallinae</i> is a flagellated protozoan parasite that affects numerous avian species worldwide, causing a range of diseases collectively termed trichomonosis. This review study aimed to present a comprehensive analysis of the prevalence of <i>T. gallinae</i> in birds of Iran, along with an exploration of its associated pathological findings. Through an extensive search of published studies, scientific databases, and relevant literature, we identified several studies conducted in Iran that focused on the prevalence of <i>T. gallinae</i> in different bird populations and their pathological effect. These studies utilized a variety of techniques, including direct microscopic examination, culture methods, and molecular tools to detect and identify the presence of this parasite. This review study indicates that <i>T. gallinae</i> infections are prevalent among various bird species in Iran, including Domestic pigeons, Zebra Finches, and Turkey. The reported prevalence rates showed significant differences among various regions and bird species, ranging from as low as 2.5% in zebra finches to as high as 70% in pigeons. The clinical signs of infected birds varied from no clinical signs to visible yellowish-white masses of caseous necrotic material, hyperplasia of mucous cells, and significant congestion of the lung. These findings underline the importance of <i>T. gallinae</i> as a significant pathogen affecting avian populations in Iran. Using at least two techniques, such as culture or PCR, in addition to direct smear is recommended for better diagnosis of infection. The present study highlights the need for further epidemiological studies to better understand the risk factors associated with <i>T. gallinae</i> transmission and to develop effective prevention and control strategies.</p>","PeriodicalId":8311,"journal":{"name":"Archives of Razi Institute","volume":"79 3","pages":"445-448"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archives of Razi InstitutePub Date : 2024-06-30eCollection Date: 2024-06-01DOI: 10.32592/ARI.2024.79.3.601
H Saberi, N Mehranfard, H Rezazadeh, M Ghasemi
{"title":"Involvement of γ-Aminobutyric Acid and N-methyl-D-aspartate Receptors in Diabetic Gastropathy in Rats: Possible Beneficial Effect of Prolonged Treatment with Insulin and Magnesium Supplement.","authors":"H Saberi, N Mehranfard, H Rezazadeh, M Ghasemi","doi":"10.32592/ARI.2024.79.3.601","DOIUrl":"10.32592/ARI.2024.79.3.601","url":null,"abstract":"<p><p>Gastrointestinal dysfunction is a severe and common complication in diabetic patients. Some evidence shows that gamma-aminobutyric acid (GABA) and glutamate contribute to diabetic gastrointestinal abnormalities. Therefore, we examined the impact of prolonged treatment with insulin and magnesium supplements on the expression pattern of GABA type A (GABA-A), GABA-B, and N-methyl-D-aspartate (NMDA) glutamate receptors as well as nitric oxide synthase 1 (NOS-1) in the stomach of type 2 diabetic rats. Twenty-four male Wistar rats were randomized to four groups (six rats each): 1) control, 2) type 2 diabetes: rats fed with a high-fat diet for three months + a low dose of streptozotocin (35 mg/kg), 3) type 2 diabetes + magnesium, and 4) type 2 diabetes + insulin. The expression of NOS-1, GABA-A, GABA-B, and NMDA receptors was detected using western blotting. The NOS-1 expression was substantially diminished (P<0.01), while the expression of GABA-A (P<0.001), GABA-B (P<0.001), and NMDA (P<0.001) receptors was enhanced in the stomach of diabetic rats relative to control. Treatment with magnesium and insulin improved NOS-1 expression in diabetic rats, although this effect was greater in magnesium treatment alone. Magnesium also restored the expression of GABA-A and GABA-B receptors in diabetic rats to control values. Moreover, insulin treatment improved GABA-A receptor expression in diabetic rats (P<0.05). No considerable alterations were detected in NMDA receptor levels in the treatment groups. The results suggest a significant role of magnesium and insulin in improving gastric motility and secretory disorders associated with diabetes through modifying the expression of GABAergic receptors.</p>","PeriodicalId":8311,"journal":{"name":"Archives of Razi Institute","volume":"79 3","pages":"601-608"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archives of Razi InstitutePub Date : 2024-06-30eCollection Date: 2024-06-01DOI: 10.32592/ARI.2024.79.3.459
M Chandela, A K Saxena, R K Mehta, S Mohanty, P Singla, A Solanki, S Jethani, B D Kamble
{"title":"Use of Tranexamic Acid in SARS-COV-2: Boon or Bane?","authors":"M Chandela, A K Saxena, R K Mehta, S Mohanty, P Singla, A Solanki, S Jethani, B D Kamble","doi":"10.32592/ARI.2024.79.3.459","DOIUrl":"10.32592/ARI.2024.79.3.459","url":null,"abstract":"<p><p>The devastating pandemic of SARS-CoV-2 (COVID-19) began in Wuhan, China, and spread rapidly through most parts of the world in the second half of 2020. The air droplet spread of SARS-CoV-2 is of great global health concern as it is potentially fatal. Various drugs and treatment modalities have been tried to date, but none have been found to be definitive. Tranexamic acid (TXA) is commonly used in pigmentary disorders in dermatology due to its ability to reduce melanocyte tyrosinase activity. It also possesses anti-fibrinolytic and anti-inflammatory properties, which have been observed to suppress the cytokine storm and modulate coagulopathy in patients suffering from COVID-19. TXA, when administered early, has been effective in decreasing the severity of symptoms in COVID-19 patients, but on the contrary, it has also been associated with life-threatening thrombosis when given as a single drug.</p>","PeriodicalId":8311,"journal":{"name":"Archives of Razi Institute","volume":"79 3","pages":"459-464"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archives of Razi InstitutePub Date : 2024-06-30eCollection Date: 2024-06-01DOI: 10.32592/ARI.2024.79.3.465
K Y Hiremath, D K Veeranagoudar, K S Bojja
{"title":"<i>Butea monosperma</i> as a collective phytomedicine and environmentally sustainable, conservative, and beneficial plant.","authors":"K Y Hiremath, D K Veeranagoudar, K S Bojja","doi":"10.32592/ARI.2024.79.3.465","DOIUrl":"10.32592/ARI.2024.79.3.465","url":null,"abstract":"<p><p>Nature is a valuable resource, supplying remedies for the treatment of all diseases. Plant kingdom stands for a plethora of natural compounds that are well known for their utilization in therapeutic applications. They may pave the way for the development of new mediators with appropriate efficacy in many pathological disorders in the future. In India and throughout the world, herbs have become a principle and popular medicine. Recognized green medicines are better than synthetic ones and have fewer side effects. Since ancient times, plants have been intended for their medicinal properties for treating various diseases owing to their fewer side effects, availability of the agent, cost-efficiency, and potential effectiveness. The medicinal value of plants stems from various vegetative parts of the plant, including flowers, fruit, bark, roots, leaves, seeds, and its modified parts. The Indian forests are the major repository of remedial and aromatic medicinal plants, which can be used for the production of a plethora of remedies against various diseases. <i>Butea monosperma</i> is one of the traditional Ayurvedic medicinal plants considered a rich source of ingredients that can be used in drug development as home remedies to treat various diseases, such as diarrhea, constipation, hypertension, dehydration, bronchial asthma, leucorrhea, cancer, infection, as well as liver and stomach disorders. The seed powder is known for its notable medicinal, pharmaceutical, and insecticidal activities. This study highlights the traditional Ayurvedic importance of an eminent medicinal plant, <i>B. monosperma</i>, with its active chemical constituents, as well as pharmacological, environmental, ecological, economical, and agricultural significance. This plant can be planted everywhere to take advantage of its versatile applications.</p>","PeriodicalId":8311,"journal":{"name":"Archives of Razi Institute","volume":"79 3","pages":"465-474"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}