American journal of veterinary research最新文献

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Customized 3-D-printed drill guide casts enable accurate wire placement for external skeletal fixation in the canine antebrachium. 定制的3d打印钻头导向铸件可以精确地放置金属丝,用于犬前臂的外部骨骼固定。
IF 1.4 3区 农林科学
American journal of veterinary research Pub Date : 2025-09-05 DOI: 10.2460/ajvr.25.06.0198
Elaina L Peterson, Mu Young Kim, Stanley E Kim
{"title":"Customized 3-D-printed drill guide casts enable accurate wire placement for external skeletal fixation in the canine antebrachium.","authors":"Elaina L Peterson, Mu Young Kim, Stanley E Kim","doi":"10.2460/ajvr.25.06.0198","DOIUrl":"https://doi.org/10.2460/ajvr.25.06.0198","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the feasibility and accuracy of customized 3-D-printed casts, created using virtual surgical planning, to guide wire placement for external skeletal fixation in the canine radius.</p><p><strong>Methods: </strong>This experimental cadaver study used normal forelimbs from medium-sized canine cadavers (19 to 23 kg). Computed tomography scans were performed to generate 3-D bone and soft tissue models. Customized 3-D-printed casts with cylindrical drill guides were designed and applied to each forelimb. Wires were drilled through the casts at distal, middle, and proximal locations along the radius and subsequently removed. Postprocedural CT scans were obtained. Pre- and postdrilling bone models were superimposed to calculate wire angle errors in the frontal and transverse planes and the distance between the planned and actual points of wire intersection (wire intersection error).</p><p><strong>Results: </strong>Both forelimbs of 6 cadavers were used. Of 72 planned wires, 70 were successfully placed. Median wire error angles were 1° in the frontal plane and 2° in the transverse plane. The median wire intersection error was 1 mm (range, 0 to 5 mm). Wire placements at proximal locations had greater error than those at middle and distal sites. No procedural complications were identified.</p><p><strong>Conclusions: </strong>Customized 3-D-printed drill guide casts enabled accurate wire placement in the canine radius with minimal deviation from planned trajectories. Proximal locations showed slightly reduced accuracy.</p><p><strong>Clinical relevance: </strong>This technique may facilitate precise and repeatable application of external skeletal fixator wires in dogs, potentially improving outcomes for limb deformity correction.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-6"},"PeriodicalIF":1.4,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histoplasma capsulatum seroprevalence in free-roaming cats from 2 endemic regions. 2个流行地区流浪猫荚膜组织浆体血清阳性率。
IF 1.4 3区 农林科学
American journal of veterinary research Pub Date : 2025-09-05 DOI: 10.2460/ajvr.25.06.0222
Jillian Myers Smith, Andrew Hanzlicek, Jennifer Weisent, Sarah Schmid, Xiaojuan Zhu, Lauren Courtney
{"title":"Histoplasma capsulatum seroprevalence in free-roaming cats from 2 endemic regions.","authors":"Jillian Myers Smith, Andrew Hanzlicek, Jennifer Weisent, Sarah Schmid, Xiaojuan Zhu, Lauren Courtney","doi":"10.2460/ajvr.25.06.0222","DOIUrl":"https://doi.org/10.2460/ajvr.25.06.0222","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate Histoplasma seroprevalence and associated risk factors in free-roaming cats from 2 endemic regions: north central Oklahoma and eastern Tennessee.</p><p><strong>Methods: </strong>Seroprevalence was determined using frozen serum samples from trap, neuter, release programs in Tennessee (n = 426) and Oklahoma (200) from 2013 to 2024. For Tennessee samples, those with complete signalment information were included. For Oklahoma samples, no demographic information was available. An anti-Histoplasma immunoglobulin G antibody enzyme immunoassay was used to evaluate for the presence of anti-Histoplasma immunoglobulin G, and results were categorized as positive, intermediate, or negative. The Fisher exact test was used to assess risk factor associations.</p><p><strong>Results: </strong>In total, 51 of 626 (8.1%) tested positive or intermediate, and 575 of 626 (91.9%) were negative. Of the samples from Tennessee, 24 of 403 (6.0%) were seropositive. From Oklahoma, 4 of 200 (2.0%) were seropositive. Of 47 Tennessee samples with positive or intermediate results, the median was 10.3 ELISA units/mL (EU; range, 8 to 31.1; positive, ≥ 10.0 EU), and of 4 Oklahoma samples with positive or intermediate results, the median was 20.3 EU (range, 18.8 to 22.6). There was no association between retrovirus infection, sex, pregnancy status, or presence of injury/disease and Histoplasma seropositivity.</p><p><strong>Conclusions: </strong>Our study is the first to document seropositivity of this regionally endemic fungus in free-roaming cats. Additional studies are encouraged to evaluate if similar seroprevalence is seen in indoor cats and if seropositivity is associated with clinical infection.</p><p><strong>Clinical relevance: </strong>Given the reported seroprevalence of histoplasmosis in felines, continued monitoring for Histoplasma infection by veterinary practitioners is warranted.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-5"},"PeriodicalIF":1.4,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commercial cytokine assay on equine cerebrospinal fluid does not distinguish equine degenerative myeloencephalopathy from cervical vertebral stenotic myelopathy. 商业细胞因子测定马脑脊液不能区分马退行性髓脑病和颈椎狭窄性脊髓病。
IF 1.4 3区 农林科学
American journal of veterinary research Pub Date : 2025-09-05 DOI: 10.2460/ajvr.25.06.0212
Flavie Payette, Jeaneen C Kulp, Amy Graves, Jennifer Janes, Jennifer Morrow, Kindra Orr, Stephen Reed, Rebecca Ruby, Darko Stefanovski, Amy L Johnson
{"title":"Commercial cytokine assay on equine cerebrospinal fluid does not distinguish equine degenerative myeloencephalopathy from cervical vertebral stenotic myelopathy.","authors":"Flavie Payette, Jeaneen C Kulp, Amy Graves, Jennifer Janes, Jennifer Morrow, Kindra Orr, Stephen Reed, Rebecca Ruby, Darko Stefanovski, Amy L Johnson","doi":"10.2460/ajvr.25.06.0212","DOIUrl":"https://doi.org/10.2460/ajvr.25.06.0212","url":null,"abstract":"<p><strong>Objective: </strong>To measure and compare CSF cytokine concentrations among horses with equine neuroaxonal dystrophy (eNAD)/equine degenerative myeloencephalopathy (EDM), horses with cervical vertebral stenotic myelopathy (CVSM), and control horses and to evaluate for associations with clinical parameters.</p><p><strong>Methods: </strong>Banked equine CSF samples from horses with neurologic disease that underwent a complete neurologic examination and postmortem diagnosis confirmation of CVSM or eNAD/EDM or from control horses were included. Cytokines were measured with an equine-specific cytokine/chemokine magnetic bead multiplex panel (23-cytokine multiplex). Results were compared between groups, and correlations with clinical parameters were evaluated.</p><p><strong>Results: </strong>Cerebrospinal fluid samples from 35 horses with CVSM, 35 horses with eNAD/EDM, and 8 control horses were analyzed. Most cytokines analyzed were below the lower limit of detection in the majority of samples. Eotaxin, IL-10, interferon-γ-induced protein 10, granulocyte colony-stimulating factor, and tumor necrosis factor-α were detectable in 5 or more samples; however, concentrations were not different between groups. Increasing sample volume or using a commercial protein-concentrating column did not enhance cytokine recovery. In horses with eNAD/EDM, IL-10 concentrations correlated with CSF phosphorylated neurofilament heavy concentrations.</p><p><strong>Conclusions: </strong>This commercial cytokine assay was unable to distinguish between CVSM and eNAD/EDM based on CSF cytokine profiles in this population.</p><p><strong>Clinical relevance: </strong>Optimization of a more sensitive assay is warranted as CSF cytokine concentrations have high potential to be used as biomarkers to characterize neuroinflammation in equine neurological diseases.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-10"},"PeriodicalIF":1.4,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interdisciplinary research seeks treatments and cures for diseases of animals and humans. 跨学科研究寻求动物和人类疾病的治疗方法。
IF 1.4 3区 农林科学
American journal of veterinary research Pub Date : 2025-09-04 DOI: 10.2460/ajvr.25.07.0274
Lisa K Nolan, Karin Allenspach, Jon P Mochel, Yana Zavros, Amy H Carter
{"title":"Interdisciplinary research seeks treatments and cures for diseases of animals and humans.","authors":"Lisa K Nolan, Karin Allenspach, Jon P Mochel, Yana Zavros, Amy H Carter","doi":"10.2460/ajvr.25.07.0274","DOIUrl":"10.2460/ajvr.25.07.0274","url":null,"abstract":"","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pradofloxacin pharmacokinetics after oral and intravenous administration in dogs reveal plasma concentrations sufficient to treat infections caused by susceptible bacteria. 口服和静脉给药后狗的药代动力学显示血浆浓度足以治疗敏感细菌引起的感染。
IF 1.4 3区 农林科学
American journal of veterinary research Pub Date : 2025-09-03 DOI: 10.2460/ajvr.25.07.0242
Mark G Papich
{"title":"Pradofloxacin pharmacokinetics after oral and intravenous administration in dogs reveal plasma concentrations sufficient to treat infections caused by susceptible bacteria.","authors":"Mark G Papich","doi":"10.2460/ajvr.25.07.0242","DOIUrl":"https://doi.org/10.2460/ajvr.25.07.0242","url":null,"abstract":"<p><strong>Objective: </strong>To determine the pharmacokinetics of pradofloxacin following oral and IV administration of a concentrated solution available in the US and whether the plasma pradofloxacin concentration would be sufficient to treat susceptible bacterial infections.</p><p><strong>Methods: </strong>Pradofloxacin was administered orally and IV as a 200-mg/mL solution at a dose of 10 mg/kg to 6 healthy dogs in a crossover study design, with treatments separated by a minimum 2-day washout period. Blood samples were collected for the measurement of plasma pradofloxacin concentration via HPLC. Pharmacokinetic analysis was performed with nonlinear mixed-effects modeling.</p><p><strong>Results: </strong>After oral administration of pradofloxacin, the peak plasma concentration was 3.4 μg/mL, and the elimination half-life was 5.42 hours, with oral bioavailability of 69%. After IV administration, the elimination half-life was 8.1 hours, systemic clearance was 0.20 L/kg/h, and volume of distribution was 2.06 L/kg.</p><p><strong>Conclusions: </strong>There were no adverse effects from direct IV injection of pradofloxacin, and the drug was well absorbed when administered orally as the solution.</p><p><strong>Clinical relevance: </strong>The concentrations from each route were sufficient to reach the free drug concentration area-under-the-curve/MIC ratio (fAUC/MIC) pharmacokinetic-pharmacodynamic targets for treating infections caused by gram-positive and gram-negative bacteria in the susceptible category of ≤ 0.25 μg/mL according to clinical breakpoints approved by the Clinical and Laboratory Standards Institute.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A combination of clinical and laboratory markers can be used as a tool to differentiate between primary and secondary immune thrombocytopenia in dogs. 临床和实验室标记的结合可以作为区分犬原发性和继发性免疫性血小板减少症的工具。
IF 1.4 3区 农林科学
American journal of veterinary research Pub Date : 2025-09-02 DOI: 10.2460/ajvr.25.06.0226
Nanna Bak-Jacobsen, Lisbeth R Jessen, Cecilie M Grønlund, Anne H Sørensen, Anne K H Krogh, Lise N Nielsen, Rebecca Langhorn
{"title":"A combination of clinical and laboratory markers can be used as a tool to differentiate between primary and secondary immune thrombocytopenia in dogs.","authors":"Nanna Bak-Jacobsen, Lisbeth R Jessen, Cecilie M Grønlund, Anne H Sørensen, Anne K H Krogh, Lise N Nielsen, Rebecca Langhorn","doi":"10.2460/ajvr.25.06.0226","DOIUrl":"https://doi.org/10.2460/ajvr.25.06.0226","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the discriminatory potential of selected clinical and routine laboratory markers to differentiate primary immune thrombocytopenia (pITP) and secondary immune thrombocytopenia (sITP) in dogs.</p><p><strong>Methods: </strong>A retrospective diagnostic accuracy study including dogs with severe immune thrombocytopenia (platelet count [PLT] < 50 X 109/L) presenting between 2014 and 2024 to a single university veterinary hospital, which were identified by laboratory database search and subsequent review of medical records.</p><p><strong>Results: </strong>The study included 17 dogs with pITP and 36 with sITP. Dogs with pITP had significantly lower PLT (median, 8 X 109/L [IQR, 3 to 21]) and C-reactive protein (CRP; median, 20.5 mg/L [IQR, 6.4 to 76.6]) compared to dogs with sITP (PLT median, 25 X 109/L [IQR, 13 to 35] and CRP median, 72.7 mg/L [IQR, 37.3 to 137.3]) and were significantly more likely to present with bleeding diathesis. The combination of bleeding diathesis, PLT < 8.5 X 109/L, and CRP < 25 mg/L had a positive likelihood ratio of 8.8 for pITP.</p><p><strong>Conclusions: </strong>The combination of bleeding diathesis, PLT, and CRP concentration shows potential for differentiating between dogs with pITP and sITP.</p><p><strong>Clinical relevance: </strong>Differentiating between pITP and sITP is imperative, as treatment is widely different. The results of the current study could potentially be used to help guide clinical decision-making.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-6"},"PeriodicalIF":1.4,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Should the canine weight-loss drug dirlotapide be resurrected? 犬类减肥药地洛他得应该复活吗?
IF 1.4 3区 农林科学
American journal of veterinary research Pub Date : 2025-08-29 DOI: 10.2460/ajvr.25.05.0175
Matthew R Krecic
{"title":"Should the canine weight-loss drug dirlotapide be resurrected?","authors":"Matthew R Krecic","doi":"10.2460/ajvr.25.05.0175","DOIUrl":"https://doi.org/10.2460/ajvr.25.05.0175","url":null,"abstract":"<p><p>The antiobesity canine drug dirlotapide, a selective microsomal triglyceride transfer protein inhibitor, was available from 2007 through 2010. Managing dogs on dirlotapide was labor intensive, and gastrointestinal side effects were unacceptable to dog owners. However, given the current popularity of glucagon-like peptide-1 agonists and increasing familiarity with their dosing and associated gastrointestinal side effects, dog owners may now be more accepting of dirlotapide.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-3"},"PeriodicalIF":1.4,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Findings from the Dog Aging Project: home-prepared diets for companion dogs feature diverse ingredients, and few are nutritionally complete. 来自狗狗衰老项目的研究结果:为伴侣狗准备的家庭饮食含有多种成分,很少有营养完整的。
IF 1.4 3区 农林科学
American journal of veterinary research Pub Date : 2025-08-27 DOI: 10.2460/ajvr.25.06.0216
Janice S O'Brien, Ellyott Lawson, M Katherine Tolbert, Audrey Ruple
{"title":"Findings from the Dog Aging Project: home-prepared diets for companion dogs feature diverse ingredients, and few are nutritionally complete.","authors":"Janice S O'Brien, Ellyott Lawson, M Katherine Tolbert, Audrey Ruple","doi":"10.2460/ajvr.25.06.0216","DOIUrl":"https://doi.org/10.2460/ajvr.25.06.0216","url":null,"abstract":"<p><strong>Objective: </strong>To qualitatively describe the home-prepared diets of dogs enrolled within the Dog Aging Project cohort and to evaluate the overall potential for the diet to be complete when possible.</p><p><strong>Methods: </strong>Free-text responses provided from January 1, 2023, through December 31, 2023, by dog owners were evaluated by 2 independent coders to describe dietary ingredients in this observational study. Five independent coders input ingredients into a website for pet owners that was designed by veterinary nutritionists to determine the overall completeness of diets.</p><p><strong>Results: </strong>Overall, 1,726 home-prepared diets were composed of a range of ingredients, which may include meat and organs, vegetables, fruits, grains, nuts and seeds, and added oils. The most common dietary ingredients were meat (90%) and vegetables (65%). Nearly half (45%) of owners added some form of commercially prepared diet or base/topper to supplement the home-prepared ingredients. Only 6% of these diets were potentially nutritionally complete according to the Association of American Feed Control Officials adult dog maintenance standards.</p><p><strong>Conclusions: </strong>The composition of home-prepared diets varied substantially in terms of ingredients, and few are likely to be nutritionally complete.</p><p><strong>Clinical relevance: </strong>Veterinarians collecting diet history information should take care to fully examine the home-prepared diets reported by owners and use a variety of tools, including consultation with board-certified veterinary nutritionists (diplomate of American College of Veterinary Internal Medicine-Nutrition), to assist owners in the selection of a maintenance diet.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-9"},"PeriodicalIF":1.4,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intra-articular injections of polynucleotides show promise in improving clinical outcomes compared to hyaluronic acid in small-breed dogs with osteoarthritis. 与透明质酸相比,关节内注射多核苷酸有望改善患有骨关节炎的小型犬的临床结果。
IF 1.4 3区 农林科学
American journal of veterinary research Pub Date : 2025-08-25 DOI: 10.2460/ajvr.25.07.0243
Chae-Lim Lee, Yongsun Kim, Jong-In Kim, Changsu Jung, Sumin Kim, Kyu-Won Kang, Byung-Jae Kang
{"title":"Intra-articular injections of polynucleotides show promise in improving clinical outcomes compared to hyaluronic acid in small-breed dogs with osteoarthritis.","authors":"Chae-Lim Lee, Yongsun Kim, Jong-In Kim, Changsu Jung, Sumin Kim, Kyu-Won Kang, Byung-Jae Kang","doi":"10.2460/ajvr.25.07.0243","DOIUrl":"https://doi.org/10.2460/ajvr.25.07.0243","url":null,"abstract":"<p><strong>Objective: </strong>To compare the therapeutic effects of IA polynucleotide (PN) and hyaluronic acid (HA) injections in small-breed dogs with osteoarthritis.</p><p><strong>Methods: </strong>A multicenter, prospective, comparative, randomized, blinded clinical study was conducted from February 2024 to January 2025 at a university veterinary hospital and 3 veterinary clinics. Client-owned small-breed dogs (< 15 kg) with hindlimb osteoarthritis, confirmed by clinical signs and radiographic findings, were assigned to receive 2 IA injections of either HA or PN at a 1:2 ratio, with a 2-week interval. Clinical outcomes were evaluated at weeks 0, 2, 4, 8, and 12 using 2 validated clinical metrology instruments, the Canine Orthopedic Index (COI; function, gait, stiffness, and quality of life) and Canine Brief Pain Inventory (CBPI; pain severity score [PSS] and pain interference score [PIS]).</p><p><strong>Results: </strong>Of the 34 enrolled dogs, 27 completed the study (HA, n = 9; PN, 18). The mean age was 6.3 years, with a median weight of 4.8 kg. The PN group showed significantly greater improvements in COI, stiffness, CBPI, and PIS compared with the HA group at week 12. The PN-treated dogs also experienced earlier or more sustained improvements in COI, stiffness, gait, CBPI, PSS, and PIS. The COI-defined success was observed from weeks 4 to 12 in the PN group and at week 8 in the HA group.</p><p><strong>Conclusions: </strong>The IA PN injections resulted in earlier, greater, and more sustained clinical improvements than HA in dogs with osteoarthritis.</p><p><strong>Clinical relevance: </strong>Injections of PN may offer a more effective alternative to HA for managing canine osteoarthritis.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of an electronic cognitive aid compared to traditional poster cognitive aids does not impact cardiopulmonary resuscitation technical nor nontechnical skills of veterinary students in a high-fidelity simulation of canine cardiopulmonary arrest. 在犬类心肺骤停高保真模拟实验中,与传统的海报认知辅助设备相比,电子认知辅助设备的使用不影响兽医学生心肺复苏的技术和非技术技能。
IF 1.4 3区 农林科学
American journal of veterinary research Pub Date : 2025-08-25 DOI: 10.2460/ajvr.25.06.0197
Maria P Vasquez, Sabrina N Hoehne, Linda Martin, Julie Cary
{"title":"The use of an electronic cognitive aid compared to traditional poster cognitive aids does not impact cardiopulmonary resuscitation technical nor nontechnical skills of veterinary students in a high-fidelity simulation of canine cardiopulmonary arrest.","authors":"Maria P Vasquez, Sabrina N Hoehne, Linda Martin, Julie Cary","doi":"10.2460/ajvr.25.06.0197","DOIUrl":"https://doi.org/10.2460/ajvr.25.06.0197","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate differences in CPR performance and user comfort with the use of traditional cognitive aids (TCAs) versus electronic cognitive aids (ECAs) in a simulation of canine cardiopulmonary arrest in veterinary student who are Reassessment Campaign on Veterinary Resuscitation-certified rescuers (CRs).</p><p><strong>Methods: </strong>This prospective study was performed in the university simulation laboratory. Two identical simulations of canine cardiopulmonary arrest were performed using TCAs or an ECA in a crossover design, and video recordings were assessed for technical and nontechnical CPR skills. Participants completed a system usability scale survey.</p><p><strong>Results: </strong>18 CRs performed simulations in groups of 6. There were no significant differences between cognitive aids in critical CPR technical skills, such as chest compression rates per minute (TCA, 110 ± 6; ECA, 108 ± 6), basic life support cycle length (seconds; TCA, 121 [range, 50]; ECA, 120 [range, 92]), time to vasopressor administration (seconds; TCA, 199 [range, 59]; ECA, 185 [range, 95]), or time to electrical defibrillation (seconds; TCA, 434 [range, 55]; ECA, 543 [range, 234]). There were no significant differences in CPR nontechnical skills (trauma nontechnical skills score: TCA, 20 [range, 6]; ECA, 23 [range, 7]) or system usability scale scores (TCA, 86 [± 9]; ECA, 78 [± 12.8]).</p><p><strong>Conclusions: </strong>The cognitive aid did not alter technical nor nontechnical skills in CPR in CRs. Certified rescuers did not prefer the use of one cognitive aid over the other based on system usability scores.</p><p><strong>Clinical relevance: </strong>The results of this study suggest that the format of the cognitive aid may not significantly influence CPR performance or user experience in certified rescuers.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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